Patents by Inventor Kenta Imai
Kenta Imai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11959914Abstract: The automatic analyzer includes: a sample dispensing unit that dispenses a sample into a reaction vessel; a reagent dispensing unit that dispenses a reagent into the reaction vessel; a control unit that controls the sample dispensing unit and the reagent dispensing unit; and a measurement unit that measures a mixed solution of the sample and the reagent mixed in the reaction vessel. The reagent includes three types of reagents of: a first reagent that specifically binds to an antigen in the sample; a second reagent that specifically binds to a site different from that to which the first reagent binds with respect to the antigen and has a label to be detected by the measurement unit; and a third reagent that specifically binds to a site different from the binding site of the first reagent and the antigen and contains insoluble carriers.Type: GrantFiled: January 29, 2019Date of Patent: April 16, 2024Assignees: HITACHI HIGH-TECH CORPORATION, ROCHE DIAGNOSTICS OPERATIONS, INC.Inventors: Tatsuki Takakura, Kenta Imai, Takaaki Hagiwara, Yoshihiro Yamashita, Taku Sakazume, Beatus Ofenloch-Haehnle, Michaela Windfuhr, Ursula Pauselius-Fuchs, Rita Haerteis
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Publication number: 20240085405Abstract: An image processing device includes a determination unit configured to determine a type of autophagy induced in a cell, based on information indicative of autophagic activity in the cell present in a cell image in which the cell is image captured and based on information indicative of congestion of molecules in the cell present in the cell image.Type: ApplicationFiled: November 22, 2023Publication date: March 14, 2024Applicants: NIKON CORPORATION, THE UNIVERSITY OF TOKYOInventors: Kenta IMAI, Mamiko Masutani, Masayuki Murata, Fumi Kano, Yoshiyuki Noguchi
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Publication number: 20240027485Abstract: There is provided an automatic analysis system that freely sets length or width dimensions to a traveling surface and that affects no influence on the layout of an automatic analyzer. In front of the automatic analyzer, a rail line is installed, and a transfer robot moves on the rail line. The rail line restrains roll, pitch, and yaw rotation directions, and thus the transfer robot does not fall. The rail line is fixed to a first jack and a second jack, each jack is in contact with the automatic analyzer and a body with no gap, and thus the roll, pitch, and yaw rotation directions of the rail line that is fixed to the jack are restrained. As a result, the length or width dimensions of a moving mechanism to the traveling surface are freely settable.Type: ApplicationFiled: October 14, 2021Publication date: January 25, 2024Inventors: Nobuya FUKUDA, Kenta IMAI
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Patent number: 11867691Abstract: An image processing device includes a determination unit configured to determine a type of autophagy induced in a cell, based on information indicative of autophagic activity in the cell present in a cell image in which the cell is image captured and based on information indicative of congestion of molecules in the cell present in the cell image.Type: GrantFiled: February 3, 2017Date of Patent: January 9, 2024Assignees: NIKON CORPORATION, THE UNIVERSITY OF TOKYOInventors: Kenta Imai, Mamiko Masutani, Masayuki Murata, Fumi Kano, Yoshiyuki Noguchi
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Publication number: 20230375580Abstract: The present invention provides a system that makes a recommendation, to an operator, of a countermeasure method considered appropriate from a precursory stage of abnormality. This recommended action notification system comprises: a plurality of automatic analyzers 51 that include a first automatic analyzer; and a learning device 52 that is connected to a network 53. The recommended action notification system is for making a recommendation to an operator for an action to be executed on the first automatic analyzer.Type: ApplicationFiled: February 17, 2021Publication date: November 23, 2023Inventors: Aika NAKAJIMA, Masahiko IIJIMA, Kenta IMAI, Shunsuke SASAKI
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Publication number: 20230341426Abstract: An automatic analyzer is capable of reducing the time required for a series of maintenance operations in that the user’s maintenance work is linked to the device driving so that the maintenance work proceeds in the order of the maintenance work tools. An automatic analyzer includes a plurality of processing units for processing a specimen: an agitation mechanism, a reagent dispensing mechanism, a mixer, an incubator, and a specimen dispensing mechanism. A control unit controls a processing unit, an analysis unit, and a display unit and causes the display unit to display a plurality of maintenance work tools used for maintenance work performed by the operator on the plurality of processing units and to display the maintenance work contents of the plurality of processing units that continuously use one of the plurality of maintenance work tools, selected by the operator via the display unit.Type: ApplicationFiled: December 14, 2020Publication date: October 26, 2023Inventors: Yusuke MIZUKI, Marina NAKAI, Shunsuke SASAKI, Kenta IMAI, Alexander SEILER, Gertraud EHRLICH-WEINREICH
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Publication number: 20230228777Abstract: An operator can perform exchange work of a reagent container without including a mechanism for reagent exchange and interrupting an analysis operation. An automatic analyzer includes: an analysis unit including a plurality of operation units for performing analysis of a specimen; and a control unit for controlling the analysis unit. The control unit allows the analysis unit to set to at least (a) an analysis operation mode in which a first and a second operation unit are operated for the analysis of the specimen, (b) a partial operation mode in which only the first operation unit is continuously operated after the analysis of the specimen is completed in the analysis operation mode, and (c) a reagent exchange mode in which consumables containing a reagent are exchangeable in the analysis unit. The control unit allows the analysis unit to shift from the partial operation mode to the reagent exchange mode.Type: ApplicationFiled: February 16, 2021Publication date: July 20, 2023Applicant: HITACH HIGH-TECH CORPORATIONInventors: Shunsuke Sasaki, Kenta Imai, Masashi Akutsu, Osamu Watabe, Satoshi Shibuya
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Patent number: 11639943Abstract: There is provided an automatic analysis device that can easily realize introduction and replacement of additional reagents in operation even in a small-scale configuration. The automatic analysis device includes a reagent dispensing mechanism 107 that dispenses a reagent from a reagent container 113 containing a reagent, and a normal reagent storage portion 130 that stores a reagent container and an additional reagent storage portion 111. The normal reagent storage portion 130 is positioned in a normal movable area 132, which is a portion of a movable area 131 of the reagent dispensing mechanism 107 and the additional reagent storage portion 111 is positioned in an area excluding the normal movable area 132 in the movable area 131 of the reagent dispensing mechanism 107.Type: GrantFiled: June 21, 2018Date of Patent: May 2, 2023Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Kenta Imai, Hiroya Umeki, Shunsuke Sasaki, Yoshihiro Yamashita, Taku Sakazume
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Publication number: 20230123687Abstract: The purpose of the present invention is to provide an automatic analysis system which, even when a large number of quality control samples is necessary, reduces the time necessary for quality control. To this end, this automatic analysis system is provided with multiple analysis devices (190), a conveyance unit (120) to which the analysis devices (190) are connected, and an operation unit (101) which operates the conveyance unit (120) to convey samples to the analysis device (190), wherein the automatic analysis system has a common storage cabinet (210) for storing the quality control samples that can be supplied to the multiple analysis devices (190), and in accordance with a rule registered in advance for each of the multiple analysis devices (190), the operation unit (101) operates the storage cabinet (210) to automatically convey a quality control sample to an analysis device (190).Type: ApplicationFiled: December 10, 2020Publication date: April 20, 2023Inventors: Shigeru YANO, Kenta IMAI, Hideto TAMEZANE, Saori CHIDA
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Publication number: 20230067353Abstract: The purpose of this invention is to provide an automated analyzer that is capable of photographing operations at a plurality of processing units while suppressing manufacturing cost growth. This automated analyzer comprises a plurality of processing units for carrying out operations related to analysis, a plurality of measurement instrument mounting parts that are disposed in each of the plurality of processing units and upon which a measuring instrument for measuring the operations of the plurality of processing units can be mounted, and a control unit for controlling the plurality of processing units. The plurality of measurement instrument mounting parts are configured such that the measuring instrument can be removed from each of the measurement instrument mounting parts and such that after being removed from one measurement instrument mounting part, the measuring instrument can be mounted on another measurement instrument mounting part.Type: ApplicationFiled: December 9, 2020Publication date: March 2, 2023Inventors: Yuki YOKOTA, Shunsuke SASAKI, Kenta IMAI, Takenori OKUSA
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Publication number: 20230010798Abstract: The invention has an object to provide an automatic analyzer and a control program that can shorten total analysis time. The automatic analyzer comprises: a sample rack that houses a sample; a sample dispensing mechanism that aspirates the sample from the sample rack and dispenses the sample into a reaction container; a plurality of detection units that detect a reaction liquid in the reaction container; and a control unit that controls the sample dispensing mechanism and the detection units. The control unit checks the measurement item specified for the sample and checks one of the detection units that is specified by the measurement item. When measurements specifying the same detection unit among the detection units are specified consecutively, the order of dispensing by the sample dispensing mechanism is changed so that measurements specifying different detection units are made consecutively.Type: ApplicationFiled: October 27, 2020Publication date: January 12, 2023Inventors: Yuichiro OTA, Kenta IMAI, Shunsuke SASAKI, Hidekazu TEZUKA, Hiroya UMEKI
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Patent number: 11549957Abstract: An automated analyzer includes an analysis operation part that causes a sample and a reagent to react and based on the reaction result performs analysis of the sample, wherein: the automated analyzer includes a plurality of units constituting the analysis operation part, a temperature adjustment mechanism that heats or cools the units, a temperature sensor that measures the temperature of the units, and a control part that controls the temperature adjustment mechanism. The control part sets the measurement startable temperature range of each unit, which is the temperature range of the operation specification thereof, and the operable temperature range, which is a temperature range that is wider than the measurement startable temperature range, and starts the analysis process of the sample when the temperature of each unit has entered the operable temperature range.Type: GrantFiled: July 25, 2016Date of Patent: January 10, 2023Assignee: Hitachi High-Tech CorporationInventors: Shunsuke Sasaki, Kenta Imai, Toshiharu Suzuki, Katsuhiko Sakamoto
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Patent number: 11519924Abstract: In order to aspire to higher sensitivity in an automatic analysis device, it is important to prevent the mixing of dust and the like in a reaction part in which a sample and a reagent react. The present invention presents an automatic analysis device that is provided with a configuration for making the pressure inside a specific block in the device such as a reaction part, or inside the device become positive. By making the pressure become positive and forming an air flow that flows out from the inside of the reaction part or the device, it is possible to limit, to a certain amount or less, the amount of dust penetrating into the reaction part.Type: GrantFiled: August 4, 2017Date of Patent: December 6, 2022Assignee: Hitachi High-Tech CorporationInventors: Daisuke Ebihara, Kenta Imai, Yoshihiro Yamashita, Shigeki Matsubara, Taku Sakazume
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Patent number: 11486890Abstract: To provide an automated analyzer capable of shortening analysis time. The automated analyzer includes a vessel which contains a mixed solution of a specimen and a reagent; and a control unit which controls a first operation performed on the vessel, a second operation performed on the vessel after the first operation, and a third operation performed on a predetermined mechanism of the automated analyzer before the second operation, in which the control unit performs the first operation and the third operation in parallel. Alternatively, the automated analyzer includes a control unit which controls a first operation performed on the vessel, a second operation performed on the vessel after the first operation, and a third operation performed on a predetermined mechanism of the automated analyzer after the first operation, in which the control unit performs the second operation and the third operation in parallel.Type: GrantFiled: November 15, 2018Date of Patent: November 1, 2022Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Kenta Imai, Shunsuke Sasaki, Hiroya Umeki, Tatsuki Takakura, Takenori Okusa, Hiroki Fujita, Taku Sakazume
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Patent number: 11340241Abstract: An automated analyzer capable of continuously performing supply of consumables is realized while continuing measurement is performed, by a simple and small amount of mechanism. An automated analyzer includes a unit that executes processing necessary for sample analysis; a consumable supply unit that supplies consumables necessary for the sample analysis to the unit; and a control device that controls operations of the unit and the consumable supply unit, in which the consumable supply unit includes a consumable container holding portion that holds a consumable storage container in which consumables is aligned and accommodated, a preliminary storage portion that temporarily holds the consumables taken out from the consumable storage container, and a transport mechanism that transports the consumables to the unit, and in which the control device transports and stores at least a portion of the consumables taken out from the consumable storage container in the preliminary storage portion.Type: GrantFiled: January 24, 2018Date of Patent: May 24, 2022Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Shunsuke Sasaki, Takenori Okusa, Yoshihiro Yamashita, Hiroki Fujita, Kenta Imai, Toshiharu Suzuki
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Publication number: 20220146540Abstract: Provided is an automatic analysis device capable of detecting a pipetting condition with high accuracy even when pressure pulsation occurs due to a pipetting syringe operation or a probe operation before and after pipetting.Type: ApplicationFiled: December 2, 2019Publication date: May 12, 2022Applicant: Hitachi High-Tech CorporationInventors: Kazuhiro NODA, Kenta IMAI, Tatsuki TAKAKURA, Nobuhiro TSUKADA
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Patent number: 11321836Abstract: An image-processing device including: a determination unit that determines a captured image on the basis of a ratio of cells and a distribution of the cells in the captured image acquired by imaging a sample including cells; and an area setting unit that sets an area used for analyzing the cells of the sample on the basis of a result of the determination acquired by the determination unit.Type: GrantFiled: April 2, 2020Date of Patent: May 3, 2022Assignees: NIKON CORPORATION, THE UNIVERSITY OF TOKYOInventors: Mamiko Masutani, Kenta Imai, Wataru Tomosugi, Takuro Saigo, Chisako Iwamoto, Masafumi Yamashita, Kenichi Ohba, Masayuki Murata, Fumi Kano, Yoshiyuki Noguchi
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Patent number: 11320443Abstract: An automatic analysis device includes a probe that performs a dispensing operation including a suction process and a discharge process with respect to liquid; a syringe that generates a pressure change for dispensing liquid at the probe; a flow path that connects the probe and the syringe with each other; a pressure sensor that measures the pressure change in the flow path at the time of liquid dispensing; a storage portion that stores a pressure change of time-series when reference fluid is discharged as a reference discharge pressure waveform; and a determination portion that determines whether or not there is an abnormality in the suction process of the sample from a relationship between a value of difference or a ratio between the reference discharge pressure waveform and the pressure waveform of a determination target at the time of discharge of liquid and normal range.Type: GrantFiled: February 15, 2018Date of Patent: May 3, 2022Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Hiroya Umeki, Kenta Imai, Yoshihiro Yamashita, Shunsuke Sasaki, Akihiro Endou
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Patent number: 11215627Abstract: In conventional automatic analyzers, there have been instances where, when a plurality of associated items are analyzed as a set item, there is high variation in the analysis data obtained using the set item, leading to a need for improvement of analysis precision. The present invention comprises performing, in mutual association, a set of preparation steps to carry out until it is time to analyze an unknown sample, the set of preparation steps including a pre-preparation step in which stirring, etc., is performed when an analysis reagent kit is mounted on the analyzer, and a step for correcting a standard curve in which correction samples that correspond to analysis items are used. This makes it possible to perform analysis after the preparation states of a plurality of analysis reagent kits are collected as needed, enabling high-precision analysis of a set item.Type: GrantFiled: July 1, 2016Date of Patent: January 4, 2022Assignees: HITACHI HIGH-TECH CORPORATION, ROCHE DIAGNOSTICS OPERATIONS, INC.Inventors: Kenta Imai, Toshiharu Suzuki, Shigeki Matsubara, Takayuki Sugime, Shunsuke Sasaki, Elke Faatz, Beatus Ofenloch-Haehnle
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Publication number: 20210341503Abstract: Provided is an automatic analyzer in which user work is in conjunction with apparatus driving and operation of a user even in complicated maintenance work is simplified. The automatic analyzer includes a measurement device 2 and a control device 3. The control device controls the measurement device. The control device includes an input unit 32 that receives a start instruction of maintenance work by a user, a control unit 31 that controls an apparatus to perform a predetermined first processing in accordance with input, a driving unit that performs driving in accordance with processing of the control unit, a display unit 33 that displays a second processing to be performed by the user in conjunction with the first processing after the first processing is terminated by the driving unit. The control device sequentially guides maintenance work of the user by performing the first processing or the second processing after the displayed second processing is executed by the user.Type: ApplicationFiled: November 13, 2019Publication date: November 4, 2021Inventors: Marina NAKAI, Tatsuki TAKAKURA, Shunsuke SASAKI, Kenta IMAI