Abstract: In a piezoelectric sensor, a method for the manufacture thereof, and an implantable lead embodying such a piezoelectric sensor, a layer of piezoelectric material, having aligned, polarized dipoles, is applied to a tubular supporting substrate, the layer of piezoelectric material having at least one electrode at an outer surface thereof and at least one electrode at an inner surface thereof. The piezoelectric material is applied on the inner circumference of the tubular supporting substrate.

Abstract: A medical system has an implantable heart stimulator with sensing and stimulating pairs of electrodes, with an electric field through the heart being generated by the respective pairs by the application of alternating voltages at a preset frequency to the respective pairs. A signal receiver receives a signal representing the voltage potential difference between the voltage potential at one of the electrodes in the pair, and a reference electrode. The detected voltage is related to the generated electric field, and the signal receiver generates a potential different signal that is supplied to a control unit to determine parameters therefrom representing cardiac activity.

Abstract: An implantable heart stimulating device has a stimulation pulse generator that emits stimulation pulses at an adjustable stimulation rate, an activity sensor that emits an activity signal in response to detected activity of the patient, and a physiological parameter sensor that generates a physiological sensor signal in response to a detected physiological parameter. The activity and physiological sensor signals are supplied to a control arrangement that sets the stimulation rate for the stimulation pulse generator by executing a stimulation rate algorithm dependent on those signals. In the stimulation rate algorithm, if the physiological signal indicates an emotional stress on the part of the patient, the stimulation rate is increased to an adjustable emotional stress rate level, and if no increase in the activity signal occurs during a predetermined time period following the stimulation rate increase, the stimulation rate is decreased.

Abstract: A method for producing a biocompatible material of the formula NaxKyNbO3, 0?x?0.8, 0.2?y?1, x+y=1 includes the steps of a) providing a Na-precursor and a K-precursor for NaxKyNbO3, b) mixing the precursors in solution wherein said precursors first react to form a sol and thereafter a gel, c) heat treating the gel to obtain an oxide of the material NaxKyNbO3, 0?x?0.8, 0.2?y?1, x+y=1. The material can be produced as a film, and the material or film can be provided on the exterior surface of a medical implant that will come into contact with body tissue and/or body fluids upon implantation thereof.

Abstract: A method, an implantable medical device, and a computer-readable medium encoded with programming instructions allow monitoring of a hematocrit value and an SvO2 level of a patient, making use of at least one medical lead connected to an implantable medical device that carries an optical sensor module that measures at least one hematocrit value and at least one SvO2 value using at least first, second and third light radiation wavelengths, by determining a present hematocrit value from at least one of the measured hematocrit values and determining a present SvO2 value from at least one of the measured SvO2 values, and determining a patient status by evaluating the present hematocrit value and the present SvO2 value, to allow a change in the patient status to be identified.

Abstract: A vessel tracking device for use with a pressure source has an elongate introduction element configured for introduction into a vessel of a human body, the introduction element having a proximal end and a distal end, and the distal end having a flexible distal end portion containing an internal cavity that is closed at the distal end. A pressure adjuster is configured for communication with said pressure source. The introduction element has a connection channel connected to the pressure adjuster at the proximal end of the introduction element, the connection channel being connected with the internal cavity and placing the internal cavity in communication with the pressure source, with the pressure adjuster controlling an internal pressure in the internal cavity. The distal end portion has different wall portions that are differently deformed as the internal pressure is adjusted, to produce a change in direction of the distal end controlled by the pressure controller.

Abstract: An implantable lead for sensing mechanical activity of a human heart has an insulating polymeric tube extending from a proximal end to a distal end of the lead, an electrical conductor provided in the lumen of the polymeric tube, and a sensor connected to the conductor at the distal end thereof. The polymeric tube is provided with a conductive surface layer along the inner face between the polymeric tube and the electrical conductor, the conductive surface layer being in electrical contact with this conductor. Accumulation of electrical charges between the electric conductor and the polymeric tube is thereby prevented.

Abstract: In a system and method for monitoring cardiac synchrony in a human heart, a first sensor is positioned at a first cardiac wall location of a heart that is subject to movements related to longitudinal valve plane movements along the longitudinal axis of the heart, and the first sensor measures said cardiac wall movements at the first cardiac wall location and emits a first sensor output signal corresponding thereto, a second sensor is positioned at a second cardiac wall location of the heart that is subject to movements related to longitudinal valve plane movements along the longitudinal axis of the heart, and the second sensor measures the cardiac wall movements at the second cardiac wall location and emits a second sensor output signal corresponding thereto.

Abstract: An implantable heart monitoring system has a control circuit that operates an implanted vibrator to emit a vibration signal that interacts with tissue in vivo. A vibration sensor detects vibrations after interaction with the tissue, and supplies a detection signal to the control circuit. The control circuit analyzes the vibrations in the detected signal relative to the vibration signal, and derives information concerning at least one mechanical property of the heart therefrom, such as stiffness and/or thickness of at least a part of the heart.

Abstract: A jetting device and a method of jetting droplets of viscous medium onto a substrate. The jetting device includes a jetting outlet through which the droplets are jetted. The jetting device further includes a wall located at the jetting outlet, downstream of the jetting outlet seen in the jetting direction. The wall is provided with an orifice through which jetted droplets are permitted to pass through. A gaseous flow is provided within the space past the jetting outlet such that an adverse effect on the performance of the jetting device is prevented, the adverse effect resulting from the accumulation of viscous medium residue at the jetting outlet.

Abstract: This invention relates to a device for jetting droplets of a particle filled viscous medium. The device has a nozzle, an eject mechanism connected to the nozzle, a medium feeding mechanism connected to the eject mechanism, a particle filled viscous medium container connected to the medium feeding mechanism, and a filter arranged between an outlet of the particle filled viscous medium container and the medium feeding mechanism.

Abstract: In a cardiac assist device and method, a microphone is placed in contact with the epicardium of the heart of a patient, and heart and lung sounds are simultaneously detected at the placement location of the microphone. The heart and lung sounds are automatically analyzed to set an appropriate cardiac therapy for the patient.

Abstract: An accelerometer has a cantilever beam supported at one end and having an opposite free end with a longitudinal direction between the supported end and the free end, the beam being formed of a piezoelectric layer and a supporting layer. An inertial, sensing mass is mounted at the free end of the beam, and is located eccentrically relative to the longitudinal direction of the beam. The accelerometer has a primary direction of sensitivity to acceleration forces, and a secondary direction of sensitivity, which is orthogonal to the primary direction and in which the sensitivity is negligible. The secondary direction forms an angle relative to the longitudinal direction of the beam such that a line coinciding with a force proceeding through the center of gravity of the inertial mass, and which is directed in the secondary direction, also intersects the beam.

Abstract: A method and a system for jetting droplets of viscous medium, such as solder paste, onto a substrate, such as an electronic circuit board. The volume of the droplets are adjusted by regulating the amount of viscous medium that is fed into a jetting nozzle for subsequent jetting of the viscous medium droplets therefrom. The exit velocity of the jetted droplets is adjusted or maintained substantially constant by regulating the velocity with which the viscous medium is impacted. Furthermore, the rate at which viscous medium is fed, for instance by a feed screw, into the nozzle is adjusted in order to regulate the feeding time required for feeding the viscous medium into the jetting nozzle, for instance in order to maintain a constant feeding time.

Abstract: An implantable medical device has a pressure sensing arrangement to measure right ventricular pressure of a heart including a pressure sensor adapted to be positioned in the right ventricle of the heart, to measure the pressure and to generate a pressure signal in response to the measured pressure. The pressure sensing arrangement also has a pressure signal processor and a timing unit. The processor determines from the pressure signal, using diastolic timing signals from the timing unit based on the pressure signal identifying the diastolic phase, a diastolic pressure signal representing the ventricular pressure only during the diastolic phase of the heart cycle.

Abstract: This invention relates to a viscous medium feeder, which has an inlet, an outlet, a tubular portion, a routable cylindrical shaft arranged in and extending coaxial with said tubular portion, and a drive motor connected to the shaft. The tubular portion has an internal thread, which is connected, at one end thereof, to the inlet, and, at the other end thereof, to the outlet. Further, the tubular portion is elastic, and the shaft abuts inner wall portions of the tubular portion. The invention also relates to a feeder tube, and a jetting device.

Abstract: A fluid pressure sensor for a lead or catheter intended for placement in a living organism, such as a human heart, includes a rigid annular or tubular supporting structure and a piezoelectric element disposed on at least a portion of the outer surface thereof. The piezoelectric element delivers an electrical signal when subjected to a pressure variation, and exhibits circumferential sensitivity. The rigidity of the sensor is defined to satisfy predetermined criteria to ensure that the sensor, when sensing pressure transferred to the sensor through an on-growth of tissue on the sensor, which is at least 90% of the signal which the sensor would emit without the on-growth.

Abstract: In an implantable intravascular pressure determining device and method, a pressure sensor generates a raw pressure signal and an acceleration sensor measures acceleration in a patient. Time intervals are identified wherein the raw pressure signal accurately represents the intravascular pressure, these intervals being identified as the time intervals wherein the measured acceleration is below a predetermined threshold. The raw pressure signal is processed, to generate a processed signal which is used as an intravascular pressure signal, only in the aforementioned time intervals.

Abstract: In an apparatus for determining the actual status of a piezoelectric sensor in a medical implant, electrical charges generated in the sensor, in response to changes in acceleration and/or gravitational force or other loads acting on the sensor, are continuously detected and the charges are then removed from the sensor, thereby maintaining the voltage across the sensor at a substantial constant zero level. The detected charges, both negative and positive, are integrated, thereby providing a resulting integrated signal representing the actual status of the sensor. The integrated signal is then evaluated for determining the physical activity and/or the posture of a patient in whom the medical implant is implanted.

Abstract: A jetting device and a method of jetting droplets of viscous medium onto a substrate. The jetting device includes a jetting outlet through which the droplets are jetted. The jetting device further includes a wall located at the jetting outlet, downstream of the jetting outlet seen in the jetting direction. The wall is provided with an orifice through which jetted droplets are permitted to pass through. A gaseous flow is provided within the space past the jetting outlet such that an adverse effect on the performance of the jetting device is prevented, the adverse effect resulting from the accumulation of viscous medium residue at the jetting outlet.