Abstract: A system and method for operating an ICE by (a) generating a running history of one or more-cylinder events per cylinder, and (b) using the running history to select a least-used non-rotating firing pattern, among a plurality of non-rotating firing patterns, provided for each firing fraction less than one (1). By making the least used selection based on the running history, unequal usage among cylinders of the ICE can be mitigated.

Abstract: The present disclosure provides chimeric antigen receptors, compostions, and methods thereof. In one embodiment the present disclosure provides a method of treating autoimmune diseases, asthma, and preventing or mediating organ rejection in a subject.

Abstract: A method for controlling a qubit encoded in an atom-like defect in a solid-state host may comprise applying an electrical signal to a piezoelectric cantilever that is mechanically coupled to a photonic waveguide comprising one or more embedded point defect sites. The photonic waveguide may be optically coupled to a photonic chip. Applying the electrical signal to the piezoelectric cantilever may induce movement in the piezoelectric cantilever, which may induce a strain in the photonic waveguide. The applied electrical signal may be determined by a defect site with excitation light, measuring a frequency of a photon emitted by the excited defect site, determining a frequency shift based on the measured frequency of the emitted photon, and determining the electrical signal to be applied to the piezoelectric cantilever based on the frequency shift.

Abstract: The present disclosure relates to compositions and methods relating to chimeric antigen receptor (CAR) polypeptides and methods relating thereto. In one embodiment, the present disclosure relates to engineered cells having chimeric antigen receptor polypeptides directed to at least two targets. In another embodiment, the present disclosure relates to engineered cells having chimeric antigen receptor polypeptides and an enhancer moiety.

Abstract: Antibody-based binding agents derived from human and camelid immunoglobulins are described, as well as strains of yeast engineered to secrete the binding agents, and methods of treating and preventing Clostridium difficile infections using the engineered strains of yeast. These binding agents recognize and bind with specificity to Clostridium difficile toxin A and/or toxin B and in some cases exhibit toxin neutralizing activity. The binding agents include camelid VHH peptide monomers, linked groups of VHH peptide monomers, VHH peptide monomers joined to antibody Fc domains, and VHH peptide monomers joined to IgG antibodies.

Abstract: Features are described for efficiently and accurately identifying a user of an electronic device with limited user interaction. The features include receiving a mobile device identifier from the mobile device. The features include transmitting the mobile device identifier to a service provider associated with the mobile device. The features include receiving information identifying the user from the service provider. The features include identifying a set of candidates associated with at least a portion of the information. The features include generating a metric for the candidates included in the set of candidates. An individual metric indicates a degree of relatedness between a value for the user for the at least one data field and a value for a candidate for the at least one data field. The features include identifying the user as a specific candidate included in the set of candidates based on the metric corresponding to a threshold.

Abstract: We disclose optical entanglement distribution in quantum networks based on a quasi-deterministic entangled photon pair source. Combining heralded photonic Bell pair generation with spectral mode conversion to interface with quantum memories eliminates switching losses due to multiplexing in the source. This zero-added-loss multiplexing (ZALM) Bell pair source is especially useful for the particularly challenging problem of long-baseline entanglement distribution via satellites and ground-based memories, where it unlocks additional advantages: (i) the substantially higher channel efficiency ? of downlinks versus uplinks with realistic adaptive optics, and (ii) photon loss occurring before interaction with the quantum memory—i.e., Alice and Bob receiving rather than transmitting—improve entanglement generation rate scaling by (?{square root over (?)}).

Abstract: Techniques for performing an emissions demand response event are described. In an example, a cloud-based HVAC control server system receives an emissions rate forecast for a predefined future time period. Using the emissions rate forecast, a plurality of emissions differential values are created for a plurality of points in time during the predefined future time period. The emissions differential values represent a change in predicted emissions over time. Based on the plurality of emissions differential values and a predefined maximum number of emissions demand response events, an emissions demand response event is generated during the predefined future time period. The cloud-based HVAC control server system then causes a thermostat to control an HVAC system in accordance with the generated emissions demand response event.

Abstract: Compositions, systems, and methods are disclosed for preparing and utilizing arrays, such as single-analyte arrays containing a plurality of fiducial elements with random spatial distributions. Arrays may be prepared with pluralities of fiducial elements comprising optically active or passive moieties. Arrays containing random spatial distributions of fiducial elements may be utilized for various array-based processes that require spatial information.

Abstract: A computer system is disclosed that provides classification-based access controls at the dataset row-level. The system may perform operations including: ingesting a dataset, wherein the dataset comprises a table of rows and columns; determining a column of the table that includes permissions information; applying parsing rules to the column to determine, for each row of the table, a list of permissions markings; receiving, from a user, a request to access the dataset; and in response to receiving the request: determining a permissions policy associated with the user; determining an evaluated policy associated with the user based on the permissions policy; filtering the table based on applying the evaluated policy associated with the user to the permissions markings of each row of the table; and providing the user access to the filtered table.

Abstract: Techniques for performing an emissions demand response event are described. In an example, a cloud-based HVAC control server system obtains an emissions rate forecast for a predefined future time period. Using the emissions rate forecast, a future emissions rate event during the predefined future time period is identified. The future emissions rate event comprises an indication of predicted magnitude and a time period when a predicted emissions rate will be at an increased or decreased level. A confidence value indicating a certainty of the future emissions rate event occurring as predicted is determined. Based on the identified future emissions rate event and the confidence value, an emissions demand response event having a start time and an end time during the future emissions rate event is generated. The cloud-based HVAC control server system then causes a thermostat to control an HVAC system in accordance with the generated emissions demand response event.

Abstract: Methods and systems are disclosed for correlating synthetic LiDAR data to a real-world domain for use in training an model for use by autonomous vehicle when operating in an environment. To do this, the system will obtain a data set of synthetic LiDAR data, along with images of a real-world environment. The system will transfer the synthetic LiDAR data to a two-dimensional representation, use the two-dimensional representation and the images to train a model that a vehicle can use to operate in a real-world environment.

Abstract: A method of operating an engine is provided. An exhaust valve actuation fault is detected for a first exhaust valve associated with a first cylinder during a first working cycle. In response to the detection of the exhaust valve actuation fault, fueling to at least the first cylinder is cut off. Actuation of the first exhaust valve is attempted in second working cycles that follow the first working cycle, wherein the second working cycles are not fueled. Whether or not the first exhaust valve actuated properly during the second working cycles is determined. Operation of the first cylinder is resumed when it is determined that the first exhaust valve actuated properly. Operation of the first cylinder is not resumed when it is determined that the first exhaust valve did not actuate properly.

Abstract: A skip fire engine controller and method of control is described wherein during transitions from a first firing density to a second firing density, a firing density and a pumping density are separately set so as to balance the conflicting demands of (a) torque control, (b) Noise, Vibration and Harshness (NVH), (c) air flow through the engine and (d) air-fuel ratio.

Abstract: A computer-implemented method comprises obtaining a first build task for building first source code in a first programming language of a plurality of programming languages; retrieving, by the processor, the first source code based on the first build task; building the first source code into one or more artifacts and one or more job specifications; storing the one or more artifacts in a cache shared across a cluster; and initializing an application module on the cluster based on the first programming language, the application module configured to receive a job specification of the one or more job specifications and execute a data transformation job using a reference to a location in the cache.

Abstract: Embodiments are directed to systems and techniques to provide smart access control devices with legacy access control systems.

Abstract: System and methods are described for optimizing exhaust flow rate and temperature during specified operational periods warm-up and keep-warm conditions, by minimizing or maximizing heat flux during those specified operational periods.

Abstract: The present invention relates to compositions and methods relating to chimeric antigen receptor (CAR) polypeptides and methods relating thereto. In one embodiment, the present invention relates to engineered cells having chimeric antigen receptor polypeptides directed to at least two targets. In another embodiment, the present invention relates to engineered cells having chimeric antigen receptor polypeptides and an enhancer moiety.

Abstract: Embodiments are directed to systems and techniques to provide smart access control devices with legacy access control systems.

Abstract: A diagnostic system and method that (a) that uses models indicative of both successful firing and skips to determine if cylinders of a skip fire controlled internal combustion engine have successfully fired or successfully skipped and (b) uses filtered exhaust gas pressure readings for detecting faults associated with EGR systems and/or turbocharger systems.