Abstract: A flexible multi-path RF adaptive tuning network switch architecture that counteracts impedance mismatch conditions arising from various combinations of coupled RF band filters, particularly in a Carrier Aggregation-based (CA) radio system. In one version, a digitally-controlled tunable matching network is coupled to a multi-path RF switch in order to provide adaptive impedance matching for various combinations of RF band filters. Optionally, some or all RF band filters include an associated digitally-controlled filter pre-match network to further improve impedance matching. In a second version, some or all RF band filters coupled to a multi-path RF switch include a digitally-controlled phase matching network to provide necessary per-band impedance matching. Optionally, a digitally-controlled tunable matching network may be included on the common port of the multi-path RF switch to provide additional impedance matching capability.

Abstract: A component for a turbine engine includes a body with an exterior surface abutting a combustion flowpath for a combustion gas flow through the turbine engine, a cooling passage defined within the body, and a trench on the exterior surface. The trench includes a plurality of outlets, and a plurality of cooling holes extending from the cooling passage to the corresponding plurality of outlets.

Abstract: A speech recognition platform configured to receive an audio signal that includes speech from a user and perform automatic speech recognition (ASR) on the audio signal to identify ASR results. The platform may identify: (i) a domain of a voice command within the speech based on the ASR results and based on context information associated with the speech or the user, and (ii) an intent of the voice command. In response to identifying the intent, the platform may perform multiple actions corresponding to this intent. The platform may select a target action to perform, and may engage in a back-and-forth dialog to obtain information for completing the target action. The action may include streaming audio to the device, setting a reminder for the user, purchasing an item on behalf of the user, making a reservation for the user or launching an application for the user.

Abstract: There are provided inter alia polypeptides capable of inhibiting IL-7 and/or L-TSLP binding to IL-7R (IL-7R), as well as to constructs and pharmaceutical compositions comprising these polypeptides.

Abstract: Provided herein are pharmaceutically acceptable sodium nitrite and pharmaceutical compositions thereof. Also provided herein are methods for determining the total non-volatile organic carbon in a sodium nitrite-containing sample. Further provided herein are methods for producing pharmaceutically acceptable sodium nitrite. Still further provided herein are methods of treatment comprising the administration of pharmaceutically acceptable sodium nitrite.

Abstract: Provided herein are pharmaceutically acceptable sodium thiosulfate and pharmaceutical compositions thereof. Also provided herein are methods for determining the total non-purgeable organic carbon in a sodium thiosulfate-containing sample. Further provided herein are methods for producing pharmaceutically acceptable sodium thiosulfate. Still further provided herein are methods of treatment comprising the administration of pharmaceutically acceptable sodium thiosulfate.

Abstract: Adaptable manufacturing systems, methods, and apparatuses are disclosed. An apparatus for manufacturing a product in accordance with the present disclosure may include a design apparatus, an assembly apparatus, and a control apparatus, coupled to the design apparatus and the assembly apparatus. The control apparatus receives input information from the design apparatus and the assembly apparatus. The control apparatus provides output information for altering at least one parameter used by at least one of the design apparatus and the assembly apparatus in the manufacture of the product.

Abstract: A flexible multi-path RF adaptive tuning network switch architecture that counteracts impedance mismatch conditions arising from various combinations of coupled RF band filters, particularly in a Carrier Aggregation-based (CA) radio system. In one version, a digitally-controlled tunable matching network is coupled to a multi-path RF switch in order to provide adaptive impedance matching for various combinations of RF band filters. Optionally, some or all RF band filters include an associated digitally-controlled filter pre-match network to further improve impedance matching. In a second version, some or all RF band filters coupled to a multi-path RF switch include a digitally-controlled phase matching network to provide necessary per-band impedance matching. Optionally, a digitally-controlled tunable matching network may be included on the common port of the multi-path RF switch to provide additional impedance matching capability.

Abstract: There is provided inter alia a construct suitable for oral administration comprising a first polypeptide and a second polypeptide connected by a labile peptide linker, wherein the labile peptide linker is labile to one or more proteases present in the intestinal tract and wherein the first and second polypeptides are substantially resistant to said one or more proteases.

Abstract: Provided herein are pharmaceutically acceptable sodium thiosulfate and pharmaceutical compositions thereof. Also provided herein are methods for determining the total non-purgeable organic carbon in a sodium thiosulfate-containing sample. Further provided herein are methods for producing pharmaceutically acceptable sodium thiosulfate. Still further provided herein are methods of treatment comprising the administration of pharmaceutically acceptable sodium thiosulfate.

Abstract: A multifunctional exercise platform comprising two elevated support platforms separated by a central deficit space. The platform includes a horizontal cross member with vertical extensions at each end, which are adjustably secured within attachment brackets mounted on the support platforms. A securing mechanism allows the horizontal cross member to be positioned at different heights. The platform features multiple band hooks for resistance training and removable platform tops that provide access to internal storage compartments within the support platforms. The platform tops can also be positioned in the central deficit space to create an inclined surface for specific exercises. The horizontal cross member is configured to support a foam pad for cushioning during exercises such as hip thrusts. The entire platform is designed to consolidate various fitness functions into a single, versatile unit, enabling users to perform a wide range of upper and lower body exercises.

Abstract: A turbine engine includes an engine core extending along an engine centerline and includes a compressor section, a combustor, and a turbine section in serial flow arrangement. A temperature sensor is provided within the engine and configured to detect a gas temperature within the engine core. A set of blades is circumferentially arranged in the turbine section. A blade in the set of blades includes an outer wall bounding an interior, a cooling conduit within the interior, and a plurality of film holes fluidly coupled to the cooling conduit.

Abstract: Methods and compositions for processing a gas produced from an oil and gas well are provided. In some embodiments, the compositions include a wellbore penetrating at least a portion of a subterranean formation. The compositions further include one or more fluid flow paths in fluid communication with the wellbore, the one or more fluid flow paths having at least a first segment and a second segment. The compositions further include at least one heat exchanger. The compositions further include an expander coupled to a generator in fluid communication with the gas in the second segment. The gas in the first segment flows through the at least one heat exchanger wherein it is cooled to the point of forming CNG, and the gas in the second segment flows through the expander to generate electricity.

Abstract: Provided herein are pharmaceutically acceptable sodium nitrite and pharmaceutical compositions thereof. Also provided herein are methods for determining the total non-volatile organic carbon in a sodium nitrite-containing sample. Further provided herein are methods for producing pharmaceutically acceptable sodium nitrite. Still further provided herein are methods of treatment comprising the administration of pharmaceutically acceptable sodium nitrite.

Abstract: A computer system receives a plurality of signals corresponding to first time-series magnetic data generated from a plurality of unshielded magnetometers proximate to the human subject. The first time-series magnetic data corresponds to magnetic fields generated from the human subject. The plurality of signals includes contributions from a biomagnetic field from at least a portion of the subject's organ and a background magnetic field. The computer system synchronizes the first time-series magnetic data to a common clock to generate synchronized time-series magnetic data. The computer system applies one or more filters to the synchronized time-series magnetic data to obtain filtered data. The computer system applies one or more noise reduction techniques to the filtered data to generate updated time-series magnetic data.

Abstract: A vehicle head unit comprising a memory configured to store an operating system, and one or more processors may be configured to perform various aspects of the techniques. The one or more processors may obtain an indication of one or more vehicle networks, and execute the operating system that presents a single application programming interface that provides function calls by which to configure the one or more vehicle networks within the operating system. The one or more processors may also configure, via the single application programming interface, one or more network interfaces for the one or more vehicle networks in the operating system by which one or more applications, executing in an application space presented by the operating system, interface with the one or more vehicle networks.

Abstract: Described herein is a polypeptide comprising an immunoglobulin chain variable domain comprising three complementarity determining regions (CDR1-CDR3) and four framework regions, wherein: (a) at least one lysine residue in CDR1, CDR2 and/or CDR3 has been substituted with at least one histidine residue, and/or (b) at least one arginine residue in CDR1, CDR2 and/or CDR3 has been substituted with at least one histidine residue. The polypeptides of this disclosure possess increased intestinal stability relative to a corresponding polypeptide not having the histidine substitutions.

Abstract: Coated articles can comprise a coating disposed over a first major surface of a substrate. The coating comprises a plurality of functionalized oligomeric silsesquioxanes and a pencil hardness of about 5H or more. In aspects, the coating comprises a linker terminated with a first functional group and a second functional group. In aspects, the coating comprises a silane coupling agent attaching the coating to the first major surface. Methods of making a coated article comprise depositing a layer comprise a plurality of functionalized oligomeric silsesquioxanes over a first major surface of a substrate and curing the layer to form the coating. Methods of forming a composition comprise reacting a plurality of functionalized oligomeric silsesquioxanes with a linker terminated with a first functional group at a first end of the linker and a second functional group at a second end of the linker opposite the first end of the linker.

Abstract: Laminates can comprise a substrate and a film. The film can comprise a film thickness from about 5 micrometers to about 400 micrometers and a tri-block copolymer comprising a first block positioned between two second blocks. The first block can be grafted with a first functional group. The first block can comprise a first glass transition temperature of about 0° C. or less. The two second blocks can each comprise a glass transition temperature of about 50° C. or more. A combined weight of the two second blocks can be from about 10 wt % to about 50 wt % of the tri-block copolymer. The film can comprise a refractive index from about 1.48 to about 1.55. Methods of forming a laminate can comprise disposing a film over a substrate. Methods can further comprise heating the film and the substrate to a first temperature and then a second temperature.