Abstract: An injection device comprising a housing in which can be mounted a syringe comprising a barrel for holding a volume of medicament, a needle at one end of the barrel and a plunger axially-moveable in the barrel to a forwardmost position, the injection device further comprising a syringe support means for supporting the barrel at an axial location at or forward of the forwardmost position of the plunger and having a reaction surface for the syringe, whereby in use said reaction surface provides an axial compressive force on said barrel when a forward axial force is applied to the plunger.

Abstract: An apparatus for replacing a human ankle joint, the apparatus comprising: a tool positioning jig for setting a position of a tool holder relative to a part of a person's anatomy; a cyclical saw removably mountable to the tool holder for making a distal tibial cut though the person's tibia bone; a talus positioning guide removably mountable to the tool holder for setting a position of location holes to be drilled in the person's talus bone; a talus re-section guide, alignable with the location holes to be drilled in the person's talus bone, for providing a cutting face for making a superior talar cut through the person's talus bone; an ankle alignment jig for setting the position of one or more slots in the person's tibia bone, the said one or more slots being configured to receive a first portion of an artificial ankle joint, and for setting the position of one or more guide holes to be drilled in the person's talus bone in order to facilitate medial, lateral, posterior and anterior alignment of the first por

Abstract: An injection device comprising a housing in which can be mounted a syringe comprising a barrel for holding a volume of medicament, a needle at one end of the barrel and a plunger axially-moveable in the barrel to a forwardmost position, the injection device further comprising a syringe support means for supporting the barrel at an axial location at or forward of the forwardmost position of the plunger and having a reaction surface for the syringe, whereby in use said reaction surface provides an axial compressive force on said barrel when a forward axial force is applied to the plunger.

Abstract: An orthopaedic surgical instrument comprising an internal support about which a plastic substrate is disposed, and which includes exposed cutting surfaces relative to the plastic substrate. The surgical instrument may have a generally hemispherical shape and the internal support may comprise a non-planar shim. In particular embodiments the shim includes multiple interconnected limbs with multiple holes or slots disposed in the limbs and with the holes or slots including the cutting surfaces.

Abstract: A locking mechanism for a polyaxial locking screwis provided, together with a polyaxial locking assembly for locking a receiving member to a substrate. Also provided is a plating system for pelvic reconstruction.

Abstract: An autoinjector comprising an outer housing in which can be mounted a syringe for holding a volume of medicament, the syringe for holding medicament having a needle at one end thereof, a syringe holder for supporting the syringe in an axial position relative to the outer housing, and an intermediate housing at least part of which is located within said outer housing, characterised in that said intermediate housing is provided with a blocking means capable of abutting the syringe or the syringe holder so as to be capable of preventing forward axial movement of the syringe when a forward axial force is applied to said needle before actuation of the autoinjector to deliver an injection, but incapable of preventing forward axial movement of the syringe during actuation of the autoinjector to deliver an injection.

Abstract: An injection device including a syringe having a needle, a barrel and a plunger. The device is configured to provide an automatic injection cycle and includes a drive coupling arrangement between a driving spring and the syringe. In operation, a drive force can be selectively transmitted between the respective first and second parts of the drive coupling arrangement depending upon their relative rotational positions such that, when the first and second parts are in a first relative rotational position during the dispensing stage, a driving force is transmitted to the plunger to drive the plunger into the barrel, and, when the first and second parts are in a second relative rotational position during the retraction stage, no force is transmitted to the plunger to allow the plunger and the syringe to retract.

Abstract: An autoinjector comprising a housing in which can be mounted a syringe comprising a barrel for holding a volume of medicament, a needle at one end of the barrel in fluid communication with the medicament and a plunger axially-moveable in the barrel to a forwardmost position, the autoinjector further comprising a syringe support means for supporting the barrel at an axial location at or forward of the forwardmost position of the plunger and having a reaction surface for the syringe, whereby in use said reaction surface (109) provides an axial compressive force on said barrel when a forward axial force is applied to the plunger.

Abstract: An orthopaedic surgical instrument comprising an internal support about which a plastic substrate is disposed, and which includes exposed cutting surfaces relative to the plastic substrate. The surgical instrument may have a generally hemispherical shape and the internal support may comprise a non-planar shim. In particular embodiments the shim includes multiple interconnected limbs with multiple holes or slots disposed in the limbs and with the holes or slots including the cutting surfaces.

Abstract: A method of manufacturing an orthopaedic surgical instrument comprising the steps of forming a generally planar shim having a predetermined shape; creating a plurality of holes or slots in the plane of the shim; temporarily shielding said holes or slots. from a plastic molding process; overmolding said shim with a plastic substrate using said plastic molding process; and creating a cutting surface at each of said holes or slots.

Abstract: An autoinjector comprising an outer housing in which is mounted a syringe comprising a barrel for holding a volume of medicament, a needle at one end of the barrel and a plunger axially-moveable in the barrel, the autoinjector further comprising an inner housing intermediate the outer housing and the syringe and an energy source in communication with said inner housing, wherein the inner housing is moveable by the energy source between three positions, namely a first position in which the inner housing is in communication with the barrel such that, in use, the plunger and barrel are moveable axially so as to move at least part of said needle out of the outer housing; a second position in which the inner housing is in communication with the plunger but not the barrel such that, in use, said plunger is moveable axially into said barrel so as to expel medicament through the needle; and a third position in which the inner housing is in communication with neither the plunger nor the barrel such that, in use,

Abstract: An autoinjector comprising an outer housing in which is mounted a syringe, the autoinjector further comprising an inner housing intermediate the outer housing and the syringe and an energy source in communication with said inner housing, wherein the inner housing is moveable by the energy source between three positions, namely a first position in.

Abstract: An autoinjector comprising an outer housing in which is mounted a syringe comprising a barrel for holding a volume of medicament, a needle at one end of the barrel and a plunger axially-moveable in the barrel, the autoinjector further comprising an inner housing intermediate the outer housing and the syringe and an energy source in communication with said inner housing, wherein the inner housing is moveable by the energy source between three positions, namely a first position in which the inner housing is in communication with the barrel such that, in use, the plunger and barrel are moveable axially so as to move at least part of said needle out of the outer housing; a second position in which the inner housing is in communication with the plunger but not the barrel such that, in use, said plunger is moveable axially into said barrel so as to expel medicament through the needle; and a third position in which the inner housing is in communication with neither the plunger nor the barrel such that, in use,

Abstract: An autoinjector comprising an outer housing in which can be mounted a syringe for holding a volume of medicament, the syringe for holding medicament having a needle at one end thereof, a syringe holder for supporting the syringe in an axial position relative to the outer housing, and an intermediate housing at least part of which is located within said outer housing, characterised in that said intermediate housing is provided with a blocking means capable of abutting the syringe or the syringe holder so as to be capable of preventing forward axial movement of the syringe when a forward axial force is applied to said needle before actuation of the autoinjector to deliver an injection, but incapable of preventing forward axial movement of the syringe during actuation of the autoinjector to deliver an injection.

Abstract: An injection device including a syringe having a needle, a barrel and a plunger. The device is configured to provide an automatic injection cycle and includes a drive coupling arrangement between a driving spring and the syringe. In operation, a drive force can be selectively transmitted between the respective first and second parts of the drive coupling arrangement depending upon their relative rotational positions such that, when the first and second parts are in a first relative rotational position during the dispensing stage, a driving force is transmitted to the plunger to drive the plunger into the barrel, and, when the first and second parts are in a second relative rotational position during the retraction stage, no force is transmitted to the plunger to allow the plunger and the syringe to retract.

Abstract: A needleless injection device comprising a cylinder for medicine having an injection nozzle at a forward end thereof and an opening at its rearward end; a piston sliding in the cylinder through said open end, in use, to drive the medicine through the nozzle; a ram to drive the piston into the cylinder and having a longitudinal axis; and a mechanical energy accumulator to drive the ram when discharged and disposed between the ram and a discharge assembly, a rear end of the ram extending into said discharge assembly; wherein the discharge assembly comprises a retention member fixed in the assembly, said retention member having a plurality of retention elements spaced around and adapted to locate on the ram when in a charged position of the ram, and a release ring surrounding said retention elements to prevent radial outward displacement thereof and discharge of the ram; and wherein axial displacement of said release ring releases said retention elements and causes discharge of the ram by said accumulator; chara

Abstract: An autoinjector comprising a housing in which can be mounted a syringe comprising a barrel for holding a volume of medicament, a needle at one end of the barrel in fluid communication with the medicament and a plunger axially-moveable in the barrel to a forwardmost position, the autoinjector further comprising a syringe support means for supporting the barrel at an axial location at or forward of the forwardmost position of the plunger and having a reaction surface for the syringe, whereby in use said reaction surface (109) provides an axial compressive force on said barrel when a forward axial force is applied to the plunger.

Abstract: An autoinjector comprising an outer housing in which is mounted a syringe, the autoinjector further comprising an inner housing intermediate the outer housing and the syringe and an energy source in communication with said inner housing, wherein the inner housing is moveable by the energy source between three positions, namely a first position in.

Abstract: An injection device comprising an outer housing inside which is located a medicament-holding barrel with a needle at one end thereof, at least part of the needle being moveable in and out of the outer housing, a plunger moveable within the barrel, an inner housing intermediate the outer housing and the barrel and plunger and an energy source in communication with said inner housing. The inner housing is moveable by the energy source between a first position in which the plunger and barrel are movable axially so as to move at least part of said needle out of the outer housing; a second position in which the plunger is movable axially into said barrel so as to expel medicament through the needle; and a third position in which the plunger and barrel are able to retract in order to retract the needle into the outer housing.