Abstract: A laser system for creating patterns on clothing includes a laser source; a phased array acousto-optic deflector (AOD) configured to control the direction and intensity of the laser beam; a computer comprising software for reading input files containing pattern designs and controlling the AOD to direct the laser beam according to the pattern designs; a fabric preparation station for washing and preparing fabric before laser treatment; a post-laser wash station for removing debris from the fabric after laser treatment; and a clothing finishing station for applying finishing touches to the fabric. The AOD includes an optical element having a surface with one or more steps formed thereon; a conductive layer formed on the surface with the steps; one or more crystals secured to each step; and electrodes positioned on each surface of each crystal.

Abstract: A tunable filter for microscope includes an optical element having a surface with one or more steps formed thereon; a conductive layer formed on the surface with the steps; one or more crystals secured to each step; and electrodes positioned on each surface of each crystal.

Abstract: A cylindrical solid-state battery and methods of making the same are disclosed. The battery includes a solid-state battery cell wound, wrapped or rolled around a core or itself, first and second terminals on opposite ends of the battery, and packaging between the first and second terminals, sealing the cell therein. The cell comprises a cathode current collector (CCC), a cathode on the CCC, a solid-state electrolyte on the cathode, an anode current collector (ACC) on the electrolyte, an insulation film on the ACC with an opening therein exposing the ACC, and a conductive redistribution layer in the opening and on the insulation film and a first sidewall of the cell. One of the terminals is electrically connected to the ACC through the redistribution layer, and the other terminal is electrically connected to the cathode or CCC on the opposite end of the battery.

Abstract: An acousto-optic deflector includes an optical element having a surface with one or more steps formed thereon; a conductive layer formed on the surface with the steps; one or more crystals secured to each step; and electrodes positioned on each surface of each crystal.

Abstract: Systems and methods are disclosed to perform isotope identification by applying an acoustic wave to an acousto-optic device to induce a frequency shift in the optical beam; adjusting the frequency of the acoustic wave to match the energy level transition of an isotope; exciting the isotope to a higher energy level through absorption of the frequency-shifted optical beam; and detecting the resulting energy level transition of the isotope.

Abstract: A solid-state battery and methods of making the same are disclosed. The battery includes a plurality of cells and first and second terminals on opposite sides/edges of the battery. Each cell includes a cathode current collector (CCC), a cathode thereon, a solid-state electrolyte, an anode current collector (ACC), a barrier/insulation film, a via/opening in the barrier/insulation film exposing the ACC, and a conductive redistribution layer on the ACC in the via/opening, on the barrier/insulation film, and on a first sidewall of each cell. The barrier/insulation film encapsulates the CCC, the cathode, the solid-state electrolyte and the ACC. The first sidewall of each cell is on one of the sides/edges of the battery. One terminal is electrically connected to each ACC through the redistribution layer, and the other is electrically connected to each cathode or CCC.

Abstract: A method for asset routing including receiving a digital asset, determining a set of print partners for the digital asset, determining a set of candidate batches for the digital asset, selecting a print partner for the digital asset, optionally determining a print partner for an unmatched digital asset, and routing the digital asset to the print partner.

Abstract: A solid-state battery and methods of making the same are disclosed. The battery includes a plurality of cells and first and second terminals on opposite sides/edges of the battery. Each cell includes a cathode current collector (CCC), a cathode thereon, a solid-state electrolyte, an anode current collector (ACC), a moat in the cathode and the electrolyte and around the ACC, a barrier/insulation film, a via/opening in the barrier/insulation film exposing the ACC, and a conductive redistribution layer in the via/opening, in the moat, on the barrier/insulation film, and on a first sidewall of each cell. The barrier/insulation film encapsulates the CCC, the cathode, the solid-state electrolyte and the ACC. One terminal is electrically connected to each ACC through the redistribution layer, and the other is electrically connected to each cathode or CCC.

Abstract: Described herein are compositions and methods for stabilizing RNA and protein antigens for long-term storage and use in transdermal microneedle patches, methods for filling microneedles, and methods of use. A stabilized RNA vaccine composition comprises: a complex of RNA with one or more cationic polymers; and one or more cationic lipid entities. A method for stabilizing RNA comprises: forming a complex comprising the RNA with one or more cationic polymers; mixing the complex with one or more cationic lipid entities comprising liposomes or lipid nanoparticles to form a lipid mixture; and drying the lipid mixture under vacuum. The compositions and methods may be employed in the preparation of vaccine medicaments.

Abstract: A method for asset routing including receiving a digital asset, determining a set of print partners for the digital asset, determining a set of candidate batches for the digital asset, selecting a print partner for the digital asset, optionally determining a print partner for an unmatched digital asset, and routing the digital asset to the print partner.

Abstract: Devices and methods provided for joint arthroscopy contemplate and enable the provision of patient specific instruments (PSI). The devices and anatomical features of a patient are rendered adjustable by the provision of conforming surfaces and support elements to account for and enable repositioning of the anatomical features during surgery. Where the joint arthroscopy involves shoulder arthroplasty, a PSI system includes at least one shoulder PSI operable to be positioned on a bone in a shoulder in the patient. The at least one shoulder PSI allow for the transfer of preoperative planning to intra-operative procedures. The at least one shoulder PSI may be virtually designed as a model based on scan data of the bone in the shoulder of the patient. The at least one shoulder PSI may be fabricated based on the virtually-designed at least one shoulder PSI model.

Abstract: A system for and a method of regulating the data interconnections between applications running on an infrastructure are provided. The system/method records access permission data into metadata embedded in the source code of each such application that regulates the data that can be received or transmitted by that application. In addition to regulating the receipt or transmission of data, the metadata can serve to provide instruction to firewalls and other regulating systems in order to configure those systems to allow the applications to receive and transmit data for which permissions have been recorded.

Abstract: A core-shell microneedle system and a method of manufacturing the microneedle system provides a pulsatile drug delivery system which is programmed to release drugs/vaccines at predictable times using biodegradable polymers and with controllable dosages. This microneedle system can be fully embedded into the skin and then release drugs/vaccines as sharp bursts in a timely manner, similar to multiple bolus injections.

Abstract: A core-shell microneedle system and a method of manufacturing the microneedle system provides a pulsatile drug delivery system which is programmed to release drugs/vaccines at predictable times using biodegradable polymers and with controllable dosages. This microneedle system can be fully embedded into the skin and then release drugs/vaccines as sharp bursts in a timely manner, similar to multiple bolus injections.

Abstract: Devices and methods provided for joint arthroscopy contemplate and enable the provision of patient specific instruments (PSI). The devices and anatomical features of a patient are rendered adjustable by the provision of guide elements and feature to account for and enable repositioning of the anatomical features during surgery. Where the joint arthroscopy involves ankle arthroplasty, a PSI system includes a tibial PSI operable to be coupled to a tibia and a talar PSI operable to be coupled to a talus. Pins pass through the tibial PSI into the tibia and through the talar PSI into the talus. The tibia and talus are aligned based on the tibial PSI, the talar PSI, the pins, and optionally a connection guide operable to receive, or be coupled to, the pins. The tibial PSI and the talar PSI allow for the transfer of pre-operative planning to intra-operative procedures.

Abstract: A method for asset routing including receiving a digital asset, determining a set of print partners for the digital asset, determining a set of candidate batches for the digital asset, selecting a print partner for the digital asset, optionally determining a print partner for an unmatched digital asset, and routing the digital asset to the print partner.

Abstract: Methods, systems, and computer-readable media for automatically detecting root causes of anomalies occurring in information technology (IT) systems are disclosed. In some embodiments, data of a service graph depicting dependencies between nodes or services of the IT infrastructure is traversed to determine propagation patterns of anomaly symptoms/alarms through the IT infrastructure. Also, a causal inference model is used to determine probabilities that an observed propagation pattern corresponds to a stored propagation pattern, wherein a close correspondence indicates that the current anomaly is likely caused by a similar root cause as a past anomaly that caused the stored propagation pattern.

Abstract: A method for asset routing including receiving a digital asset, determining a set of print partners for the digital asset, determining a set of candidate batches for the digital asset, selecting a print partner for the digital asset, optionally determining a print partner for an unmatched digital asset, and routing the digital asset to the print partner.

Abstract: A system for and a method of regulating the data interconnections between applications running on an infrastructure are provided. The system/method records access permission data into metadata embedded in the source code of each such application that regulates the data that can be received or transmitted by that application. In addition to regulating the receipt or transmission of data, the metadata can serve to provide instruction to firewalls and other regulating systems in order to configure those systems to allow the applications to receive and transmit data for which permissions have been recorded.

Abstract: A system for and a method of regulating the data interconnections between applications running on an infrastructure are provided. The system/method records access permission data into metadata embedded in the source code of each such application that regulates the data that can be received or transmitted by that application. In addition to regulating the receipt or transmission of data, the metadata can serve to provide instruction to firewalls and other regulating systems in order to configure those systems to allow the applications to receive and transmit data for which permissions have been recorded.