Abstract: Provided are a method and apparatus for determining specificity of a candidate probe.

Abstract: Provided herein is a surface acoustic wave (SAW) sensor device including a surface acoustic wave sensor and an oscillator corresponding to the surface acoustic wave sensor. A horizontal plane defined by the oscillator is inclined at a predetermined angle with respect to a horizontal plane defined by the surface acoustic wave sensor. The predetermined angle is greater than zero degrees.

Abstract: A genetic polymorphism associated with myocardial infarction is provided. More particularly, provided are a polynucleotide including a single nucleotide polymorphism (SNP) or a haplotype associated with myocardial infarction, a polynucleotide hybridized with the polynucleotide, a polypeptide encoded by one of the polynucleotides, an antibody bound to the polypeptide, a microarray and a kit including one of the polynucleotides, a myocardial infarction diagnosis method, a SNP detecting method and a method of screening pharmaceutical compositions for myocardial infarction.

Abstract: An apparatus introducing a fluid using a centrifugal force includes an introduction member including a chip receiver and a fluid introduction reservoir, the chip receiver receiving a first part of a microfluidic chip, the first part including an inlet, the fluid introduction reservoir storing a fluid to be introduced to the microfluidic chip, the fluid introduction reservoir having an exit formed to correspond to the inlet of the microfluidic chip received in the chip receiver, and a support member supporting a second part of the microfluidic chip, wherein the microfluidic chip is disposed between the introduction member and the support member, the apparatus is rotatable in a state where the introduction member is closer to a center of rotation than the microfluidic chip, and the fluid is introducible from the fluid introduction reservoir through the inlet into the microfluidic chip due to a centrifugal force generated by rotation.

Abstract: Provided is a method of storing a reagent in a microfluidic device. The reagent, in a liquid form, is loaded into reaction chambers arranged on the microfluidic device; followed by lyophilization as being contained in the microfluidic device.

Abstract: An apparatus introducing a fluid using a centrifugal force includes an introduction member including a chip receiver and a fluid introduction reservoir, the chip receiver receiving a first part of a microfluidic chip, the first part including an inlet, the fluid introduction reservoir storing a fluid to be introduced to the microfluidic chip, the fluid introduction reservoir having an exit formed to correspond to the inlet of the microfluidic chip received in the chip receiver, and a support member supporting a second part of the microfluidic chip, wherein the microfluidic chip is disposed between the introduction member and the support member, the apparatus is rotatable in a state where the introduction member is closer to a center of rotation than the microfluidic chip, and the fluid is introducible from the fluid introduction reservoir through the inlet into the microfluidic chip due to a centrifugal force generated by rotation.

Abstract: A method of positively detecting toxic materials within a sample, the method including contacting sub-mitochondrial particles having competent mitochondrial enzymes formed from inner membranes of mitochondria, an electron donor which transmits electrons to an electron transfer system of the sub-mitochondrial particles and the sample, and forming reaction resultants, adjusting a pH of a pH indicator which change color according to a change in pH, adding the pH indicators to each reaction resultant and identifying color changes of the pH indicator. Also provided is a kit for positively detecting toxic materials within a sample.

Abstract: A method and apparatus for searching a gene sequence. The gene sequence search method includes receiving the gene sequence from a user, generating extended sequences including the received gene sequence, partial sequences included in the gene sequence and an inverse sequence complementary to the gene sequence, storing the gene sequence, the extended sequences, the partial sequences, the inverse sequence and input-related record information in a database, integrated-searching the gene sequence using a gene sequence search server, estimating a gene sequence search ranking for a predetermined period using the database and outputting an integrated and searched result of the gene sequence and a gene sequence search ranking result to the user.

Abstract: A genetic polymorphism associated with myocardial infarction is provided. More particularly, a polynucleotide including a single nucleotide polymorphism (SNP) associated with myocardial infarction, a complementary polynucleotide of the nucleotide sequences, a polynucleotide hybridized with one of the polynucleotides, a polypeptide encoded by one of the polynucleotides, an antibody bound to the polypeptide, a microarray and a kit including the polynucleotides, a myocardial infarction diagnosis method, a SNP detecting method and a method of screening pharmaceutical compositions for myocardial infarction are provided.

Abstract: A genetic polymorphism associated with myocardial infarction is provided. More particularly, provided are a polynucleotide including a single nucleotide polymorphism (SNP) associated with myocardial infarction, a polynucleotide hybridized with the polynucleotide, a polypeptide encoded by one of the polynucleotides, an antibody bound to the polypeptide, a microarray and a kit including one of the polynucleotides, a myocardial infarction diagnosis method, a SNP detecting method and a method of screening pharmaceutical compositions for myocardial infarction.

Abstract: Provided are a method and apparatus for analyzing genotype data plotted in a two-dimensional space. The method includes: connecting points representing the genotype data to a predetermined point to form straight lines and obtaining angles between adjacent straight lines; extracting the two largest angles from the obtained angles; and analyzing the plotted genotype data using three groups of the genotype data separated by the two extracted largest angles. According to the present invention, when the experimental results of classifying genotype are to be analyzed, the two largest angles from the angles obtained by connecting straight lines between points representing each of the genotype data and a predetermined point plotted in a two-dimensional space are detected, and three data regions separated by the detected two largest angles are used to analyze the genotype data. Thus, a large amount of the experimental data for classifying the genotype can be analyzed rapidly and conveniently.

Abstract: Provided is a system for searching for patent documents by using a DNA fragment number. The system includes a DNA fragment sequence database storing information about DNA fragment sequences; a patent sequence database storing information about patent DNA fragment sequences of patent documents; a patent database storing information about patent documents; an interface receiving a DNA fragment number from a client; a sequence extracting unit extracting a DNA fragment sequence corresponding to the DNA fragment number from the DNA fragment sequence database; a matching sequence search unit searching for patent DNA fragment sequences matching the extracted DNA fragment sequence in the patent sequence database; a patent number extracting unit searching for patent numbers of patent documents including the patent DNA fragment sequences from the patent sequence database; and a patent search unit searching for patent documents from the patent database by inputting the extracted patent numbers.

Abstract: A sequence indexing method includes: parsing a patent document having a sequence number and a sequence list on the basis of a typical expression of a country to which the patent document was registered; first extracting the sequence number and the sequence list from the parsed patent document; and second extracting a sequence, which corresponds to the extracted sequence number, from the extracted sequence list.

Abstract: Pure 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one or a pharmaceutically acceptable salt thereof is prepared in a high yield by a simple process which reacts 1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one with a 2-methylimidazole derivative in an organic solvent or in a mixture of an organic solvent and water in the presence of a halosilane compound.

Abstract: Pure -1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one or a pharmaceutically acceptable salt thereof is prepared in a high yield by a simple process which reacts 1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one with a 2-methylimidazole derivative in an organic solvent or in a mixture of an organic solvent and water in the presence of a halosilane compound.