Patents by Inventor Kirk M. Ririe

Kirk M. Ririe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10413905
    Abstract: A temperature cycling system (10, 110) is provided for repeatedly heating and cooling a reaction mixture (16). The system (10, 110) includes a first heater (27) and a second heater (28) each movable between a first orientation in which the first or second heater (27, 28) affects the temperature of the reaction mixture (16) and a second orientation in which the first or second heater (27, 28) does not substantially affect the temperature of the reaction mixture (16). During temperature cycling, the second heater (28) is in the second orientation when the first heater (27) is in the first orientation, and the second heater (28) is in the first orientation when the first heater (27) is in the second orientation.
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: September 17, 2019
    Assignee: BioFire Defense, LLC
    Inventor: Kirk M. Ririe
  • Publication number: 20180326424
    Abstract: Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyses include nucleic acid amplification and detection and immuno-PCR.
    Type: Application
    Filed: July 25, 2018
    Publication date: November 15, 2018
    Inventors: Kirk M. Ririe, Cynthia L. Phillips
  • Patent number: 10058868
    Abstract: Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyses include nucleic acid amplification and detection and immuno-PCR.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: August 28, 2018
    Assignee: BioFire Diagnostics, LLC
    Inventors: Kirk M. Ririe, Michael R. Newswander, Randy P. Rasmussen, Mark Aaron Poritz, Stewart Benjamin Smith, David E. Jones, Gary Clark Kessler
  • Patent number: 10053728
    Abstract: Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyzes include high density nucleic acid amplification and detection and immune-PCR.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: August 21, 2018
    Assignee: BioFire Diagnostics, LLC
    Inventors: Kirk M. Ririe, Mark Aaron Poritz
  • Publication number: 20180216164
    Abstract: Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyses include high density nucleic acid amplification and detection and immune-PCR.
    Type: Application
    Filed: March 19, 2018
    Publication date: August 2, 2018
    Inventors: Kirk M. Ririe, Mark Aaron Poritz, Randy P. Rasmussen
  • Publication number: 20170165672
    Abstract: A temperature cycling system (10, 110) is provided for repeatedly heating and cooling a reaction mixture (16). The system (10, 110) includes a first heater (27) and a second heater (28) each movable between a first orientation in which the first or second heater (27, 28) affects the temperature of the reaction mixture (16) and a second orientation in which the first or second heater (27, 28) does not substantially affect the temperature of the reaction mixture (16). During temperature cycling, the second heater (28) is in the second orientation when the first heater (27) is in the first orientation, and the second heater (28) is in the first orientation when the first heater (27) is in the second orientation.
    Type: Application
    Filed: January 18, 2017
    Publication date: June 15, 2017
    Inventor: Kirk M. Ririe
  • Patent number: 9586208
    Abstract: A temperature cycling system (10, 110) is provided for repeatedly heating and cooling a reaction mixture (16). The system (10, 110) includes a first heater (27) and a second heater (28) each movable between a first orientation in which the first or second heater (27, 28) affects the temperature of the reaction mixture (16) and a second orientation in which the first or second heater (27, 28) does not substantially affect the temperature of the reaction mixture (16). During temperature cycling, the second heater (28) is in the second orientation when the first heater (27) is in the first orientation, and the second heater (28) is in the first orientation when the first heater (27) is in the second orientation.
    Type: Grant
    Filed: July 5, 2013
    Date of Patent: March 7, 2017
    Assignee: BioFire Defense, LLC
    Inventor: Kirk M. Ririe
  • Publication number: 20150322491
    Abstract: Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyses include high density nucleic acid amplification and detection and immune-PCR.
    Type: Application
    Filed: July 16, 2015
    Publication date: November 12, 2015
    Inventors: Kirk M. Ririe, Gary Clark Kessler, Dave E. Jones, Mark Aaron Poritz
  • Patent number: 9102911
    Abstract: Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyses include high density nucleic acid amplification and detection and immuno-PCR.
    Type: Grant
    Filed: January 28, 2013
    Date of Patent: August 11, 2015
    Assignee: BioFire Diagnostics, LLC
    Inventors: Kirk M. Ririe, Gary Clark Kessler, Dave E. Jones, Mark Aaron Poritz
  • Publication number: 20150099291
    Abstract: Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyses include nucleic acid amplification and detection and immuno-PCR.
    Type: Application
    Filed: December 12, 2014
    Publication date: April 9, 2015
    Inventors: Kirk M. Ririe, Michael R. Newswander, Randy P. Rasmussen, Mark Aaron Poritz, Stewart Benjamin Smith, David E. Jones, Gary Clark Kessler
  • Patent number: 8940526
    Abstract: Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyzes include nucleic acid amplification and detection and immuno-PCR.
    Type: Grant
    Filed: February 12, 2013
    Date of Patent: January 27, 2015
    Assignee: BioFire Diagnostics, LLC
    Inventors: Kirk M. Ririe, Michael R. Newswander, Randy P. Rasmussen, Mark Aaron Poritz, Stewart Benjamin Smith, David E. Jones, Gary Clark Kessler
  • Patent number: 8895295
    Abstract: Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyses include high density nucleic acid amplification and detection and immuno-PCR.
    Type: Grant
    Filed: November 14, 2007
    Date of Patent: November 25, 2014
    Assignee: Biofire Diagnostics, LLC
    Inventors: Kirk M. Ririe, Gary Clark Kessler, David E. Jones, Mark Aaron Poritz
  • Patent number: 8394608
    Abstract: Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analysis include nucleic acid amplification and detection and immuno-PCR.
    Type: Grant
    Filed: May 8, 2006
    Date of Patent: March 12, 2013
    Assignee: BioFire Diagnostics, Inc.
    Inventors: Kirk M. Ririe, Michael R. Newswander, Randy P. Rasmussen, Mark Aaron Poritz, Stewart Benjamin Smith, David E. Jones, Gary Clark Kessler
  • Patent number: 8343754
    Abstract: The present invention is directed to devices for performing PCR and monitoring the reaction of a sample comprising a nucleic acid and a fluorescent dye. Illustrative devices comprise a heat exchange component for heating and cooling the sample, a control device for repeatedly operating the heat exchange component to subject the sample to thermal cycling, an excitation source for optically exciting the sample to cause the sample to fluoresce, a photodetector for detecting temperature-dependent fluorescence levels from the sample, and a processor configured to record and process emissions from the fluorescent dye.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: January 1, 2013
    Assignees: University of Utah Research Foundation, BioFire Diagnostics, Inc.
    Inventors: Carl T. Wittwer, Kirk M. Ririe, Randy P. Rasmussen
  • Publication number: 20120258524
    Abstract: The present invention is directed to devices for performing PCR and monitoring the reaction of a sample comprising a nucleic acid and a fluorescent dye. Illustrative devices comprise a heat exchange component for heating and cooling the sample, a control device for repeatedly operating the heat exchange component to subject the sample to thermal cycling, an excitation source for optically exciting the sample to cause the sample to fluoresce, a photodetector for detecting temperature-dependent fluorescence levels from the sample, and a processor configured to record and process emissions from the fluorescent dye.
    Type: Application
    Filed: May 7, 2012
    Publication date: October 11, 2012
    Inventors: Carl T. Wittwer, Kirk M. Ririe, Randy P. Rasmussen
  • Patent number: 7745205
    Abstract: A thermal cycling method and device is disclosed. The device comprises a sample chamber whose temperature can be rapidly and accurately modulated over a range of temperatures needed to carry out a number of biological procedures, such as the DNA polymerase chain reaction. Biological samples are placed in containers each comprising a reservoir and a reaction portion, wherein the reaction portion has a small volume. The small volume reaction portion permits the rapid and accurate temperature modulation. With an optically transmissible reaction portion, DNA amplification may be monitored by fluorescence during PCR.
    Type: Grant
    Filed: August 9, 2004
    Date of Patent: June 29, 2010
    Assignee: University of Utah Research Foundation
    Inventors: Carl T. Wittwer, Kirk M. Ririe
  • Publication number: 20100105029
    Abstract: Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyses include nucleic acid amplification and detection and immuno-PCR.
    Type: Application
    Filed: May 8, 2006
    Publication date: April 29, 2010
    Inventors: Kirk M. Ririe, Michael R. Newswander, Randy P. Rasmussen, Mark Aaron Poritz, Stewart Benjamin Smith, David E. Jones, Gary Clark Kessler
  • Publication number: 20100056383
    Abstract: Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyses include high density nucleic acid amplification and detection and immuno-PCR.
    Type: Application
    Filed: November 14, 2007
    Publication date: March 4, 2010
    Inventors: Kirk M. Ririe, Gary Clark Kessler, David E. Jones, Mark Aaron` Poritz
  • Patent number: 7670832
    Abstract: The present invention is directed to devices for performing PCR and monitoring the reaction of a sample comprising a nucleic acid and a fluorescent dye. Illustrative devices comprise a heat exchange component for heating and cooling the sample, a control device for repeatedly operating the heat exchange component to subject the sample to thermal cycling, an excitation source for optically exciting the sample to cause the sample to fluoresce, a photodetector for detecting temperature-dependent fluorescence levels from the sample, and a processor configured to record and process emissions from the fluorescent dye.
    Type: Grant
    Filed: August 15, 2005
    Date of Patent: March 2, 2010
    Assignees: University of Utah Research Foundation, Idaho Technology, Inc.
    Inventors: Carl T. Wittwer, Kirk M. Ririe
  • Publication number: 20090311673
    Abstract: The present invention is directed to devices for performing PCR and monitoring the reaction of a sample comprising a nucleic acid and a fluorescent dye. Illustrative devices comprise a heat exchange component for heating and cooling the sample, a control device for repeatedly operating the heat exchange component to subject the sample to thermal cycling, an excitation source for optically exciting the sample to cause the sample to fluoresce, a photodetector for detecting temperature-dependent fluorescence levels from the sample, and a processor configured to record and process emissions from the fluorescent dye.
    Type: Application
    Filed: October 31, 2007
    Publication date: December 17, 2009
    Inventors: Carl T. Wittwer, Kirk M. Ririe, Randy P. Rasmussen