Patents by Inventor Kirk Mykytyn

Kirk Mykytyn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification of a gene causing the most common form of Bardet-Biedl syndrome and uses thereof
    Publication number: 20060110761
    Abstract: The present invention relates to the identification of a gene, mutated at the most common locus now designated BBS1, that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypogonadism, mental retardation, renal cancer and other renal abnormalities, retinopathy and polydactyly or limb deformities. The human BBS1 protein disclosed herein is composed of 17 exons and spans approximately 23 kb. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described.
    Type: Application
    Filed: November 8, 2005
    Publication date: May 25, 2006
    Inventors: Val Sheffield, Kirk Mykytyn, Darryl Nishimura, Edwin Stone, Charles Searby
  • Bardet-biedl susceptibility gene and uses thereof
    Patent number: 7045317
    Abstract: The present invention relates to the identification of a gene, now designated BBS4, that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypertension, mental retardation, renal cancer and other abnormalities, retinopathy and hypogonadism. The human BBS4 protein disclosed herein is 519 amino acids in length and is coded for by a gene spanning 16 exons. Homologs have been identified in mouse, rat, zebrafish. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described.
    Type: Grant
    Filed: April 2, 2002
    Date of Patent: May 16, 2006
    Assignee: University of Iowa Research Foundation
    Inventors: Val C. Sheffield, Kirk Mykytyn, Edwin M. Stone
  • Identification of a gene causing the most common form of bardet-biedl syndrome and uses thereof
    Patent number: 6962788
    Abstract: The present invention relates to the identification of a gene, mutated at the most common locus now designated BBS1, that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypogonadism, mental retardation, renal cancer and other renal abnormalities, retinopathy and polydactyly or limb deformities. The human BBS1 protein disclosed herein is composed of 17 exons and spans approximately 23 kb. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described.
    Type: Grant
    Filed: May 28, 2003
    Date of Patent: November 8, 2005
    Assignee: University of Iowa Research Foundation
    Inventors: Val C. Sheffield, Kirk Mykytyn, Darryl Y. Nishimura, Edwin M. Stone, Charles C. Searby
  • Identification of a gene causing the most common form of Bardet-Biedl Syndrome and uses thereof
    Publication number: 20030232375
    Abstract: The present invention relates to the identification of a gene, mutated at the most common locus now designated BBS1, that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypogonadism, mental retardation, renal cancer and other renal abnormalities, retinopathy and polydactyly or limb deformities. The human BBS1 protein disclosed herein is composed of 17 exons and spans approximately 23 kb. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described.
    Type: Application
    Filed: May 28, 2003
    Publication date: December 18, 2003
    Applicant: The University of Iowa Research Foundation
    Inventors: Val C. Sheffield, Kirk Mykytyn, Darryl Y. Nishimura, Edwin M. Stone, Charles C. Searby
  • Bardet-biedl susceptibility gene and uses thereof
    Publication number: 20030170645
    Abstract: The present invention relates to the identification of a gene, now designated BBS4, that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypertension, mental retardation, renal cancer and other abnormalities, retinopathy and hypogonadism. The human BBS4 protein disclosed herein is 519 amino acids in length and is coded for by a gene spanning 16 exons. Homologs have been identified in mouse, rat, zebrafish. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described.
    Type: Application
    Filed: April 2, 2002
    Publication date: September 11, 2003
    Inventors: Val C. Sheffield, Kirk Mykytyn, Edwin M. Stone