Patents by Inventor Kiyozo Asada

Kiyozo Asada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hyperthermostable protease gene
    Patent number: 5756339
    Abstract: There is disclosed a hyperthermostable protease gene originating in Pyrococcus furiosus, in particular, a hyperthermostable protease gene encoding the amino acid sequence represented by the SEQ ID NO 1 in the Sequence Listing or a part thereof which retains the activity of the hyperthermostable protease. There is also disclosed a process for producing the protease by culturing a transformant transformed with a plasmid into which the above gene has been inserted.
    Type: Grant
    Filed: December 13, 1996
    Date of Patent: May 26, 1998
    Assignee: Takara Shuzo Co., Ltd.
    Inventors: Masanori Mitta, Katsuhiko Yamamoto, Mio Morishita, Kiyozo Asada, Susumu Tsunasawa, Ikunoshin Kato
  • Hyperthermostable .beta.-galactosidase gene, enzyme encoded thereby, and process for production
    Patent number: 5744345
    Abstract: An isolated hyperthermostable .beta.-galactosidase gene derived from Pyrococcus furiosus is described. Examples include DNA sequences shown in SEQ ID NO. 2 and SEQ ID NO. 4 and DNAs hybridizable with these DNAs. A method of cloning the hyperthermostable .beta.-galactosidase gene in which each of the above sequences or portions thereof is used as a probe or primer is described. A process for producing a hyperthermostable .beta.-galactosidase by culturing a transformant into which a plasmid containing each of the above genes has been introduced is described. A particularly preferred gene encodes an SDS-resistant hyperthermostable .beta.-galactosidase.
    Type: Grant
    Filed: June 14, 1995
    Date of Patent: April 28, 1998
    Assignee: Takara Shuzo Co., Ltd.
    Inventors: Atsushi Shimada, Miki Odate, Nobuto Koyama, Kimikazu Hashino, Kiyozo Asada, Ikunoshin Kato
  • DNA encoding a protein comprising calmodulin-and actin-binding human caldesmon peptide fragment
    Patent number: 5739008
    Abstract: Provided are functional peptide fragments of human caldesmon having calmodulin and actin-binding activity, the amino acid sequences and nucleic acid sequences therefor.
    Type: Grant
    Filed: April 10, 1996
    Date of Patent: April 14, 1998
    Assignees: Kenji Sobue, Takara Shuzo Co., Ltd.
    Inventors: Ken'ichiro Hayashi, Takashi Hashida, Kiyozo Asada, Hirokazu Kotani, Ikunoshin Kato, Kenji Sobue
  • Proteins comprising calmodulin- and actin-binding human caldesmon polypeptide fragments
    Patent number: 5532337
    Abstract: Provided are functional peptide fragments of human caldesmon having calmodulin and actin-binding activity, the amino acid sequences and nucleic acid sequences therefor.
    Type: Grant
    Filed: August 4, 1994
    Date of Patent: July 2, 1996
    Assignees: Kenji Sobue, Takara Shuzo Co., Ltd.
    Inventors: Ken'ichiro Hayashi, Takashi Hashida, Kiyozo Asada, Hirokazu Kotani, Ikunoshin Kato, Kenji Sobue
  • Endo-xyloglucan transferase
    Patent number: 5516694
    Abstract: Endo-xyloglucan transferases responsible for growth of plant cell wall, genes coding for the enzymes, a method of transferring xyloglucan molecules by using the enzyme, and methods of using the gene are described.
    Type: Grant
    Filed: January 31, 1995
    Date of Patent: May 14, 1996
    Assignee: Takara Shuzo Co., Ltd.
    Inventors: Kazuhiko Nishitani, Kazuhide Okazawa, Kiyozo Asada, Ikunoshin Kato
  • .alpha.-amylase gene
    Patent number: 5366883
    Abstract: The present invention relates, in general, to a cloned .alpha.-amylase gene, and, in particular, to a cloned hyperthermophilic .alpha.-amylase gene and to methods of producing .alpha.-amylase using same.
    Type: Grant
    Filed: June 9, 1992
    Date of Patent: November 22, 1994
    Assignees: Takara Shuzo Co., Ltd., The Johns Hopkins University
    Inventors: Kiyozo Asada, Takashi Uemori, Hiroyuki Mukai, Ikunoshin Kato, Kenneth Laderman, Christian B. Anfinsen
  • Gene encoding aspartic acid secretory proteinase of Candida albicans and a method of using the gene for the detection of Candida albicans
    Patent number: 5332660
    Abstract: This invention is directed to a gene sequence for secretory aspartic proteinase (SEQ ID No. 1) which is specific to pathogenic Candida yeast, to a highly sensitive method for detection of said gene in a sample solution and a kit used therefor.
    Type: Grant
    Filed: March 15, 1993
    Date of Patent: July 26, 1994
    Assignee: Takara Shuzo Co., Ltd.
    Inventors: Osamu Takeda, Hiroyuki Mukai, Kiyozo Asada, Hideyo Yamaguchi, Ikunoshin Kato
  • Human calpastatin-like polypeptide
    Patent number: 5189144
    Abstract: Polypeptides are provided which have a calpain inhibitory activity. The polypeptides have an activity like that of natural human calpastatin but are significantly shorter in length than natural human calpastatin. The polypeptides are suited for synthetic manufacture.
    Type: Grant
    Filed: March 17, 1992
    Date of Patent: February 23, 1993
    Assignee: Takara Shuzo Co., Ltd.
    Inventors: Kiyozo Asada, Takashi Uemori, Masahiro Endo, Fusao Kimizuka, Ikunoshin Kato