Abstract: An electrically active electrode element for an implantable electrode lead, having an electrode, which includes an electrically active electrode surface facing toward the outside, and an elongated electric feed line, which is capable of establishing an electric connection to an electrically active implant at the proximal end thereof, and which is embodied as an electrically conducting cable end-to-end, wherein the cable forms the electrode at the distal end thereof. A related electrode lead having such an electrode element is provided, and a method for the production of said electrode line utilizing the electrode element is also provided.

Abstract: A terminal part for an electrode line for connection to an implantable heart stimulator, the terminal part having multiple annular, electrically conductive contacts of equal external diameter having insulation sections of the same external diameter situated between them in the longitudinal direction, of which the electrically conductive contacts are each electrically connected to an electrically conductive terminal line, the terminal part being formed by multiple insulating adapters and by electrical contacts held thereby having terminal lines fastened thereon, which are plugged together and connected using a thermoplastic injection molding compound after being plugged together, the terminal part otherwise being implemented in such a way that it is to be connected as an independent unit to a remaining electrode line.

Abstract: A device for the in vivo determination of the blood flow rate in a patient's blood vessel includes a microelectrode arrangement provided for placement in the blood vessel, an electrical power source which provides excitation energy having physiologically harmless parameters for obtaining a measured signal, a signal detector for detecting an electrical measured signal resulting from the blood flow in the presence of the excitation energy at measuring electrodes of the microelectrode arrangement, and a signal evaluation device, connected to the signal detector, for determining the blood flow rate on the basis of the measured signal.

Abstract: The invention relates to a connecting piece for connecting to an electrode line and to an electric implant, whereby the connecting piece has an electrically conducting plug module, multiple ring-shaped electrically conducting contacts with insulation sections having the same outside diameter arranged in the longitudinal direction therebetween, multiple electric connecting lines, and a supporting element which supports the insulation sections and secures them in the radial direction. A through-bore situated within the supporting element receives the plug module and/or a feeder line of an electrode body. The supporting element has grooves spaced along the longitudinal direction, and recesses extending from the proximal end to the distal end and running parallel to the longitudinal axis wherein the electric connecting lines are fit.

Abstract: Implantable shock electrode line having a proximal end for connection to an implantable device which generates shock pulses, and a distal segment which has a shock electrode, wherein an area ratio of the shock electrode area to the surface area of the shock electrode line is not constant over the longitudinal extent of the shock electrode.

Abstract: Implantable electrode lead for stimulation in or on the heart, comprising a body having an insulating and sealing outer surface, at least one electrical connection between an outwardly electrically active region having a connecting unit for the electrical connection to a cardiac pacemaker, cardioverter/defibrillator or other suitable electrically active implantable device, and an active or passive fixation. To reduce the electrical resistance while, at the same time, providing for a long life, the outwardly electrically active regions are manufactured with a component of high bioresistance, biocompatibility and non-toxicity, and a component with low electrical resistance.

Abstract: The invention relates to a connecting piece for connecting to an electrode line and to an electric implant, whereby the connecting piece has an electrically conducting plug module, multiple ring-shaped electrically conducting contacts with insulation sections having the same outside diameter arranged in the longitudinal direction therebetween, multiple electric connecting lines, and a supporting element which supports the insulation sections and secures them in the radial direction. A through-bore situated within the supporting element receives the plug module and/or a feeder line of an electrode body. The supporting element has grooves spaced along the longitudinal direction, and recesses extending from the proximal end to the distal end and running parallel to the longitudinal axis wherein the electric connecting lines are fit.

Abstract: This invention is directed to a crystalline acid of a lipoxin A4 analog of Formula (II): wherein: R1 is —O—, —S(O)t— (where t is 0, 1 or 2), or a straight or branched alkylene chain; and R2 is aryl (optionally substituted by one or more substituents selected from alkyl, alkoxy, halo, haloalkyl and haloalkoxy) or aralkyl (optionally substituted by one or more substituents selected from f alkyl, alkoxy, halo, haloalkyl and haloalkoxy); and wherein the compound of Formula (II) is a single stereoisomer or any mixture of stereoisomers. This crystalline acid is useful in treating disease-states characterized by inflammation, such as inflammatory and autoimmune disorders or pulmonary or respiratory tract inflammations in humans. Methods of preparing the crystalline acid are also described.

Abstract: A terminal part for an electrode line for connection to an implantable heart stimulator, the terminal part having multiple annular, electrically conductive contacts of equal external diameter having insulation sections of the same external diameter situated between them in the longitudinal direction, of which the electrically conductive contacts are each electrically connected to an electrically conductive terminal line, the terminal part being formed by multiple insulating adapters and by electrical contacts held thereby having terminal lines fastened thereon, which are plugged together and connected using a thermoplastic injection molding compound after being plugged together, the terminal part otherwise being implemented in such a way that it is to be connected as an independent unit to a remaining electrode line.

Abstract: This invention is directed to the crystalline potassium salt of a lipoxin A4 analog of Formula (I): processes for preparing the crystalline potassium salts, methods for using them to treat disease-states characterized by inflammation, and pharmaceutical compositions comprising such crystalline potassium salts.

Abstract: This invention is directed to a crystalline acid of a lipoxin A4 analog of Formula (II): wherein: R1 is —O—, —S(O)t— (where t is 0, 1 or 2), or a straight or branched alkylene chain; and R2 is aryl (optionally substituted by one or more substituents selected from alkyl, alkoxy, halo, haloalkyl and haloalkoxy) or aralkyl (optionally substituted by one or more substituents selected from f alkyl, alkoxy, halo, haloalkyl and haloalkoxy); and wherein the compound of Formula (II) is a single stereoisomer or any mixture of stereoisomers. This crystalline acid is useful in treating disease-states characterized by inflammation, such as inflammatory and autoimmune disorders or pulmonary or respiratory tract inflammations in humans. Methods of preparing the crystalline acid are also described.

Abstract: An implantable electrode device, in particular an ICD electrode device, comprises an electrode main body and at least one electrode situated thereon, the electrode including a wire material forming undercuts and/or intermediate spaces between its wires, such as a wire braid or an open wire coil. A medication depot filling is introduced into the under-cuts and/or intermediate spaces.

Abstract: Implantable electrode lead for stimulation in or on the heart, comprising a body having an insulating and sealing outer surface, at least one electrical connection between an outwardly electrically active region having a connecting unit for the electrical connection to a cardiac pacemaker, cardioverter/defibrillator or other suitable electrically active implantable device, and an active or passive fixation. To reduce the electrical resistance while, at the same time, providing for a long life, the outwardly electrically active regions are manufactured with a component of high bioresistance, biocompatibility and non-toxicity, and a component with low electrical resistance.

Abstract: Electrostimulator (2), comprising an interface for connecting a working electrode (2), as well as a pulse generator that is connected on the output side to the interface for transmitting electrical pulses to the working electrode (10), with a first measuring instrument (10) that is connected to the interface for measuring the electrical voltage present at the interface and/or the electrical current flowing over the interface, as well as an arithmetic unit, connected on the input side to the first measuring instrument, for computing an output signal reflecting the capacity of the working electrode in dependence on the current and/or voltage at the interface.

Abstract: An implantable apparatus for the early diagnosis of tachycardia in the heart is provided witha microelectrode array, which is in contact with the cardiac muscle tissue, for detecting stimulus conduction potentials in the cardiac muscle tissue,a measuring device, which is in connection with the microelectrode array, for determining the refractory time of the cardiac muscle cells in the monitored cardiac region,a measuring device, which is in connection with the microelectrode array, for determining the stimulus conduction velocity in the monitored cardiac muscle region,a computing device for determining the product value of the refractory time and the stimulus conduction velocity,a comparator for comparing the product value with a tachycardia threshold, any falling short of the tachycardia threshold signaling a condition of the heart in risk of tachycardia,a stimulation arrangement for generating antitachycardia stimulation upon detection of a condition of risk of tachycardia in particular via the microelectro

Abstract: A method and apparatus for forming slabs and shaped bars of food material such as fish or meat. The material is extruded at a very high pressure while deep frozen and via an extrusion nozzle which is shaped to build up back pressure to improve uniformity of extrusion.