Patents by Inventor Klaus Jelich
Klaus Jelich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5756752Abstract: Substituted oxadiazolones of the formula (I) ##STR1## in which R represents optionally substituted alkyl, are obtained in good yields and high purity on reacting in a first step carboxylic acids of the general formula (II)R--COOH (II)with hydrazine hydrate in the presence of a catalyst and an inert diluent at temperatures between 0.degree. C. and 150.degree. C. with elimination of water and removal of said catalyst and reacting the resulting carboxylic hydrazides of the general formula (III)R--CO--NH--NH.sub.2 (III)in a second step with phosgene (COCl.sub.2) at temperatures between 20.degree. C. and 120.degree. C.Type: GrantFiled: April 15, 1997Date of Patent: May 26, 1998Assignees: Bayer Corporation, Bayer AktiengesellschaftInventors: Hans Joachim Diehr, Reinhard Lantzsch, Jacqueline M. Applegate, Klaus Jelich
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Patent number: 5675010Abstract: The present invention relates to new chloropyridinium chlorides of the general formula (I) ##STR1## in which R.sup.1 represents in each case optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkylalkyl, arylalkyl or heteroarylalkyl,R.sup.2 represents optionally substituted alkyl, andR.sup.3 represents hydrogen, halogen or optionally substituted alkyl,to a process for their preparation and to their use for the preparation of chloropyridines.Type: GrantFiled: May 8, 1996Date of Patent: October 7, 1997Assignee: Bayer AktiengesellschaftInventors: Reinhard Lantzsch, Klaus Jelich, Carl Casser, Christoph Mannheims, Knud Lawrenz
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Patent number: 5648495Abstract: The present invention relates to a process for the preparation of 5-substituted 2-chloropyridines of the formula (I) ##STR1## by reaction of acetenamides of the formula (II) ##STR2## with Vilsmeier reagent, which is prepared by reaction of dialkylformamides of the formula (III) ##STR3## with a chlorinating agent, the excess of which is removed from the reaction mixture by distillation or by addition of dialkylformamide after completion of the reaction of the Vilsmeier reagent with the acetenamide of the formula (II), wherein in the formulae (I)-(III):R represents optionally substituted alkyl or aralkyl,R.sup.1 represents C.sub.1 -C.sub.4 -alkyl or aryl-C.sub.1 -C.sub.4 -alkyl,R.sup.2 and R.sup.3 represent straight-chain, branched or cyclic C.sub.4 -C.sub.8 -alkyl.Type: GrantFiled: January 11, 1996Date of Patent: July 15, 1997Assignee: Bayer AktiengesellschaftInventors: Klaus Jelich, Hans Lindel, Christoph Mannheims, Reinhard Lantzsch, Walter Merz
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Patent number: 5541332Abstract: A process for the preparation of a chloropyridine of the formula ##STR1## which comprises reacting an enamide of the formula ##STR2## with a chlorinating agent in the presence of a di-substituted formamide ##STR3## in which R.sup.4 and R.sup.5 each individually is alkyl or cycloalkyl or together are alkanediyl, at a temperature between about -30.degree. C. and 100.degree. C., thereby to produce a compound of the formula ##STR4## and subjecting said compound to thermal cleavage. Compounds I are novel. Compounds IV are known intermediates for agrochemicals and pharmaceuticals.Type: GrantFiled: January 4, 1995Date of Patent: July 30, 1996Assignee: Bayer AktiengesellschaftInventors: Reinhard Lantzsch, Klaus Jelich, Carl Casser, Christoph Mannheims, Knud Lawrenz
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Patent number: 5502194Abstract: A process for the preparation of a 2-halogeno-pyridine of the formula ##STR1## in which X represents halogen andY represents halogen, nitro, formyl, cyano, carboxyl, carbamoyl, alkyl, halogenoalkyl, alkoxyalkyl, dialkoxyalkyl, alkoxycarbonyl, alkylaminocarbonyl or dialkylaminocarbonyl,which comprises in a first stage reacting a pyridine 1-oxide of the formula ##STR2## with an organic nitrogen base A and an electrophilic compound, optionally in the presence of a diluent, to produce a compound of the formula ##STR3## in which A represents the radical of an organic nitrogen base, andZ.sup.- represents an anion formed from an electrophilic compound,optionally isolating and optionally purifying the compound of the formula (III).Type: GrantFiled: March 31, 1994Date of Patent: March 26, 1996Assignee: Bayer AktiengesellschaftInventors: Eric Rivadeneira, Klaus Jelich
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Patent number: 5463065Abstract: A 2-dialkylamino-5-methyl-pyridine of the formula ##STR1## in which R is C.sub.1 -C.sub.4 -alkyl.Type: GrantFiled: April 18, 1994Date of Patent: October 31, 1995Assignee: Bayer AktiengesellschaftInventors: Eric Rivadeneira, Klaus Jelich
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Patent number: 5440051Abstract: Aryl ethers are chlorinated in the .alpha.-position by a process in which they are metered into a reaction vessel at the same time as chlorine, the reaction being carried out at temperatures in the range from 60.degree. to 150.degree. C.Type: GrantFiled: March 22, 1994Date of Patent: August 8, 1995Assignee: Bayer AktiengesellschaftInventors: Albrecht Marhold, Klaus Jelich
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Patent number: 5334724Abstract: A process for the preparation of a substituted 2-chloropyridine derivatives of the formula ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 represent hydrogen or various other radicals, which comprises reacting a pyridine-1-oxide of the formula ##STR2## with an aromatic carbonyl chloride in the presence of an inert organic solvent and in the presence of an acid acceptor at a temperature between about -20.degree. C. and 200.degree. C.Type: GrantFiled: June 24, 1992Date of Patent: August 2, 1994Assignee: Bayer AktiengesellschaftInventors: Dieter Kaufmann, Klaus Jelich, Rudolf Braden, Winfried Rosen
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Patent number: 5332824Abstract: The invention relates to a novel process and novel intermediates for the preparation of 2-amino-5-methylpyridine (I) ##STR1## The process is characterized in that in a first step 3-methyl-pyridine 1-oxide of the formula (II) ##STR2## is reacted with a trialkylamine of the general formula (III)R.sub.3 N (III)in whichR represents alkyl,and with an electrophilic compound, in the presence or absence of a diluent, to give the ammonium salt of the general formula (IV) ##STR3## in which R has the abovementioned meaning andZ.sup..crclbar. represents an anion formed from an electrophilic compound, the compound (IV)is, possibly, isolated as a crude intermediate and, possibly, further purified and then in a second step the ammonium salt of the formula (IV) is reacted with hydrogen bromide, in the presence or absence of a diluent, at temperatures between 150.degree. C. and 300.degree. C.The compound (I) is an intermediate for the preparation of agrochemicals, for example of herbicides.Type: GrantFiled: April 6, 1993Date of Patent: July 26, 1994Assignee: Bayer AktiengesellschaftInventors: Eric Rivadeneira, Klaus Jelich
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Patent number: 5329011Abstract: A process for the preparation of a 2-chloro-5-chloro-methyl-pyridine, of the formula (I) ##STR1## comprising reacting a 2-alkoxy-5-alkoxymethylpyridine derivative of the formula (II) ##STR2## in which R.sup.1 represents alkyl, with a chlorinating agent, if appropriate, in the presence of a diluent and if appropriate, in the presence of a reaction auxiliary, at a temperature between 0.degree.C. and 200.degree.C.Type: GrantFiled: June 7, 1993Date of Patent: July 12, 1994Assignee: Bayer AktiengesellschaftInventor: Klaus Jelich
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Patent number: 5288732Abstract: Novel fungicides of the formula ##STR1## in which R.sup.1 represents optionally substituted hydroxyalkyl, optionally substituted hydroxyalkoxyalkyl, optionally substituted heteroarylalkyl or optionally substituted heteroaryl, andR.sup.2 represents optionally substituted alkyl, optionally substituted alkenyl, or alkinyl.Intermediates therefor, wherein R.sup.2 is hydrogen or an alkali metal cation, are also new.Type: GrantFiled: March 31, 1993Date of Patent: February 22, 1994Assignee: Bayer AktiengesellschaftInventors: Herbert Gayer, Klaus Jelich, Winfried Lunkenheimer, Wilhelm Brandes, Gerd Hanssler
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Patent number: 5258526Abstract: A process for the preparation of 3-substituted 4-cyanopyrrole compounds of the formula (I) ##STR1## in which Ar has the meaning given in the description, by reaction in a 1st stage of bromides (II)Ar--Br (II)with acrylonitrile in the presence of a solvent and a suitable reaction auxiliary to give acrylonitrile derivatives (III)Ar--CH.dbd.CH--CN (III)and in a 2nd stage with a phenylsulphonylmethyl isocyanide (IV)Ph--SO.sub.2 --CH.sub.2 --CN (IV)in the presence of a solvent and optionally in the presence of a suitable reaction auxiliary, characterised in that the 1st stage is carried out in the presence of a palladium catalyst and the 2nd stage in the presence of a 1.2- to 1.8-fold molar excess of alkali metal alcoholate or alkali metal hydroxide.Type: GrantFiled: February 28, 1992Date of Patent: November 2, 1993Assignee: Bayer AktiengesellschaftInventors: Peter C. Knuppel, Reinhard Lantzsch, Klaus Jelich, Peter Andres, Albrecht Marhold
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Patent number: 5250498Abstract: A method of combating unwanted vegetation which comprises applying to such vegetation or to a locus from which it is desired to exclude such vegetation, a herbicidally effective amount of a 2-iminopyridine of the formula ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 independently of one another represent hydrogen, halogen, alkyl, halogenoalkyl, alkoxy, halogenoalkoxy, alkylthio or halogenalkylthio,R.sup.Type: GrantFiled: December 7, 1990Date of Patent: October 5, 1993Assignee: Bayer AktiengesellschaftInventors: Roland Andree, Hauke Furstenwerth, Klaus Jelich, Gunther Beck, Peter Babczinski, Klaus Lurssen, Hans-Joachim Santel, Robert R. Schmidt
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Patent number: 5233043Abstract: A process for the preparation of a 2-alkoxy-5-alkoxymethylpyridine derivative of the formula (II) ##STR1## in which R.sup.1 represents alkyl, comprising reacting a 3-dichloromethylpyridine, of the formula III, ##STR2## with an alcohol of the formula R.sup.1 --OH (IV) and with the corresponding alkali metal alkoxide of this alcohol, at a temperature between 0.degree. C. and 150.degree. C.Type: GrantFiled: December 2, 1991Date of Patent: August 3, 1993Assignee: Bayer AktiengesellschaftInventor: Klaus Jelich
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Patent number: 5116993Abstract: A process for the preparation of a 2-chloro-5-chloromethyl-pyridine, of the formula (I) ##STR1## comprising reacting a 2-alkoxy-5-alkoxymethylpyridine derivative of the formula (II) ##STR2## in which R.sup.1 represents alkyl,with a chlorinating agent, is appropriate, in the presence of a diluent and if appropriate, in the presence of a reaction auxiliary, at a temperature between 0.degree. C. and 200.degree. C.Type: GrantFiled: September 11, 1991Date of Patent: May 26, 1992Assignee: Bayer AktiengesellschaftInventor: Klaus Jelich
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Patent number: 5103011Abstract: In the preparation of 2-chloro-5-methyl-pyridine of the formula ##STR1## by reacting 3-methyl-pyridine-1-oxide of the formula ##STR2## with a chlorinating agent, the improvement which comprises effecting the reaction in the presence of a chlorinating agent of the formula ##STR3## in which A represents oxygen or the grouping ##STR4## in which R.sup.2 and R.sup.3 individually represent alkyl, cycloalkyl or aryl or together represent alkanediyl or oxaalkanediyl andR.sup.1 represents hydrogen, chlorine, alkyl, cycloalkyl, aryl or the grouping ##STR5## in which R.sup.2 and R.sup.3 have the abovementioned meanings,and where, if R.sup.1 represents aryl, A must represent the grouping ##STR6## in the presence of a basic organic nitrogen compound and in the presence of a diluent at a temperature between about -20.degree. C. and +120.degree. C. The product is known to be useful in the systhesis of pharmaceuticals and insecticides.Type: GrantFiled: January 23, 1991Date of Patent: April 7, 1992Assignee: Bayer AktiengesellschaftInventors: Klaus Jelich, Dieter Kaufmann, Bernd Gallenkamp, Reinhard Lantzsch
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Patent number: 5099025Abstract: A process for the preparation of 2-chloro-5-methylpyridine of the formula ##STR1## which comprises reacting 3-methyl-pyridine-1-oxide of the formula ##STR2## with a chlorinating agent of the formula ##STR3## in which R.sup.1 represents alkyl, halogenoalkyl, cycloalkyl, optionally substituted aryl, NR.sup.2 R.sup.3 or OR.sup.4 in whichR.sup.2 and R.sup.3 individually represent alkyl, cycloalkyl or aryl or together represent alkanediyl or oxaalkanediyl andR.sup.4 represents alkyl, cycloalkyl or optionally substituted aryl,in the presence of a basic organic nitrogen compound and in the presence of a diluent at a temperature between about -20.degree. C. and +150.degree. C.Type: GrantFiled: June 14, 1991Date of Patent: March 24, 1992Assignee: Bayer AktiengesellschaftInventors: Dieter Kaufmann, Klaus Jelich
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Patent number: 5091068Abstract: A process for the preparation of 3-trichloromethylpyridine of the formula ##STR1## which comprises reacting 3-methyl-pyridine hydrogen sulphate of the formula ##STR2## with elemental chlorine which exposure to at least one of visible and ultraviolet light at a temperature between about 70.degree. C. and 150.degree. C.Type: GrantFiled: September 28, 1990Date of Patent: February 25, 1992Assignee: Bayer AktiengesellschaftInventors: Klaus Jelich, Hans Lindel
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Patent number: 5051513Abstract: A process for the preparation of a chlorinated nicotinaldehyde of the formula ##STR1## in which X is hydrogen or chlorine, which comprises in a first step reacting a 6-alkoxynicotinaldehyde of the formula ##STR2## in which R is alkyl, with a chlorinating agent at a temperature from about 0.degree. C. to 200.degree. C. to form a dichloromethylpyridine of the formula ##STR3## and then in a second step reacting the dichloromethylpyridine with water at a temperature from about 0.degree. C. to 110.degree. C. The products are known intermediates for pharmaceuticals and plant protection agents.Type: GrantFiled: July 10, 1990Date of Patent: September 24, 1991Assignee: Bayer AktiengesellschaftInventor: Klaus Jelich
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Patent number: 5013351Abstract: Novel herbicides of the formula ##STR1## in which R.sup.1 represents --CH.sub.2 --O--R.sup.5 and at the same time R.sup.2 represents alkyl, orR.sup.2 represents --CH.sub.2 --O--R.sup.5 and at the same time R.sup.1 represents alkyl,R.sup.3 represents hydrogen, alkyl, alkylcarbonyl, alkoxycarbonyl, alkylsulphonyl, alkenyl or alkinyl, or represents optionally substituted aralkyl,R.sup.4 represents aryl or heteroaryl, in each case optionally substituted, andR.sup.5 represents alkyl.Type: GrantFiled: April 7, 1989Date of Patent: May 7, 1991Assignee: Bayer AktiengesellschaftInventors: Klaus Jelich, Wolfgang Kramer, Hans-Joachim Santel, Robert R. Schmidt, Harry Strang