Patents by Inventor Klaus Stockhaus

Klaus Stockhaus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions containing a 1-(thienyl-methyl)-2-anilino-2-imidazoline and method of use
    Patent number: 3998956
    Abstract: Pharmaceutical compositions containing as an active ingredient a compound of the formula ##STR1## wherein R, R.sub.1 and R.sub.2 are each hydrogen, fluorine, chlorine, bromine, methyl, ethyl, methoxy, trifluoromethyl or cyano, andR.sub.5 is hydrogen, methyl or ethyl, or a non-toxic, pharmaceutically acceptable acid addition salt thereof; and a method of using the same as analgesics and hypotensives.
    Type: Grant
    Filed: December 10, 1975
    Date of Patent: December 21, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Helmut Stahle, Herbert Koppe, Werner Kummer, Klaus Stockhaus
  • Pharmaceutical compositions containing an N-[1-(.omega.-phenyl-alkyl) -piperidyl-4]-N- (.alpha.-pyridyl)-carboxylic acid amide and method of use
    Patent number: 3993762
    Abstract: Pharmaceutical compositions containing as an active ingredient a compound of the formula ##SPC1##WhereinR is straight or branched alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 2 carbon atoms or phenyl, andn is an integer from 2 to 4, inclusive,Or a non-toxic, pharmacologically acceptable acid addition salt thereof; and a method of using the same as non-narcotic analgesics.
    Type: Grant
    Filed: November 18, 1975
    Date of Patent: November 23, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Adolf Langbein, Herbert Merz, Gerhard Walther, Klaus Stockhaus
  • Pharmaceutical compositions containing an N-(furyl-methyl)-6,14-(endoethano or endoetheno)-7.alpha.-hydroxyalkyl-tetrahydro-noroipavine or -northebaine and method of use
    Patent number: 3992542
    Abstract: Pharmaceutical compositions containing as an active ingredient a compound of the formula ##SPC1##WhereinR.sub.1 is hydrogen, methyl or acetyl,R.sub.2 is hydrogen or methyl,R.sub.3 is hydrogen, methyl, n-propyl, phenethyl, or phenyl,R.sub.4 is hydrogen or methyl, andZ is --CH=CH-- or --CH.sub.2 --CH.sub.2 --,or a non-toxic, pharmacologically acceptable acid addition salt thereof; and a method of using the same as analgesics and antitussives.
    Type: Grant
    Filed: October 30, 1975
    Date of Patent: November 16, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Adolf Langbein, Herbert Merz, Gerhard Walther, Klaus Stockhaus
  • 2-Tetrahydrofurfuryl-5-(methyl or phenyl)-9.beta.-methyl-2'-oxy-6,7-benzomorphans and salts thereof
    Patent number: 3982005
    Abstract: Compounds of the formula ##SPC1##Wherein R.sub.1 is methyl or phenyl, andR.sub.2 is hydrogen, methyl or acetyl, and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful as analgesics.
    Type: Grant
    Filed: July 30, 1975
    Date of Patent: September 21, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Herbert Merz, Adolf Langbein, Gerhard Walther, Klaus Stockhaus
  • N-[(Methoxymethyl-furyl)-methyl]-morphinans or -6,7-benzomorphans and salts thereof
    Patent number: 3981874
    Abstract: Compound of the formula ##SPC1##WhereinR.sub.1 and R.sub.2, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 3 carbon atoms,R.sub.3 is hydrogen or methyl,R.sub.4 is ##SPC2##R.sub.5 is hydrogen, methyl or acetyl,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as analgesics.
    Type: Grant
    Filed: October 15, 1974
    Date of Patent: September 21, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Herbert Merz, Adolf Langbein, Gerhard Walther, Klaus Stockhaus
  • Pharmaceutical compositions containing an N-(furyl- or thienyl-methyl)-desoxy-normorphine or norcodeine and method of use
    Patent number: 3975368
    Abstract: Pharmaceutical compositions containing as an active ingredient a compound of the formula ##SPC1##WhereinR is hydrogen, methyl or acetyl,R' is hydrogen or methyl, andX is oxygen or sulfur,Or a non-toxic, pharmacologically acceptable acid addition salt thereof; and a method of using the same as opiate antagonists, analgesics and antitussives.
    Type: Grant
    Filed: October 8, 1975
    Date of Patent: August 17, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Gerhard Walther, Herbert Merz, Adolf Langbein, Klaus Stockhaus
  • 2-Phenylamino-imidazolines-(2)
    Patent number: 3937717
    Abstract: 2-Phenylamino-imidazolines-(2) of the formula ##SPC1##Wherein R, R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, fluorine, chlorine, bromine, methyl, ethyl, methoxy, trifluoromethyl and cyano and one of R.sub.3 and R.sub.4 being hydrogen while the other is ##EQU1## and R.sub.5 is selected from the group consisting of hydrogen, methyl and ethyl and their non-toxic, pharmaceutically acceptable acid addition salts which have analgesic and blood pressure reducing properties and their preparation.
    Type: Grant
    Filed: February 11, 1974
    Date of Patent: February 10, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Helmut Stahle, Herbert Koppe, Werner Kummer, Klaus Stockhaus
  • N-(1-(.omega.-phenyl-alkyl)-piperidyl-4)-N-(.alpha.-pyridyl)-carboxylic acid amides and salts thereof
    Patent number: 3933832
    Abstract: Compounds of the formula ##SPC1##WhereinR is straight or branched alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 2 carbon atoms or phenyl, andn is an integer from 2 to 4, inclusive,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful as non-narcotic analgesics.
    Type: Grant
    Filed: August 14, 1974
    Date of Patent: January 20, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Adolf Langbein, Herbert Merz, Gerhard Walther, Klaus Stockhaus
  • 2-Heteroaryl-methyl)-5,9.beta.-dialkyl-6,7-benzomorphans and salts thereof
    Patent number: 3931194
    Abstract: Compounds of the formula ##SPC1##Wherein R is hydrogen, methyl or acetyl,R.sub.1 and R.sub.2, which may be identical to or different from each other, are each alkyl of 1 to 3 carbon atoms,R.sub.3 is hydrogen or methyl, andY is oxygen or sulfur,And non-toxic, pharmacologically acceptable acid addition salts thereof; these compounds as well as the salts are useful as analgesics and antitussives, and opiate antagonists.
    Type: Grant
    Filed: June 5, 1973
    Date of Patent: January 6, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Herbert Merz, Adolf Langbein, Klaus Stockhaus, Helmut Wick
  • N-(heteroaryl-methyl)-7.alpha.-acyl-6,14-(endoetheno or endoethano)-tetrahydro-nororipavines or-thebaines and salts thereof
    Patent number: 3931187
    Abstract: Compounds of the formula ##SPC1##WhereinR is hydrogen, methyl or acetyl,R.sub.1 is methyl, phenyl, or hydrogen,Z is --CH=CH-- or --CH.sub.2 --CH.sub.2 --,Y is oxygen or sulfur, andR.sub.3 is hydrogen or methyl,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as analgesics and antitussives.
    Type: Grant
    Filed: June 13, 1973
    Date of Patent: January 6, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Adolf Langbein, Herbert Merz, Gerhard Walther, Klaus Stockhaus