Abstract: In order to provide a variable folder which allows smearing-free operation, the cutting blade of an upstream cross-cutting arrangement is provided with recesses, which leave behind residual crosspieces in the strand which is to be cut, and arranged in the product-directing region, between the cross-cutting arrangement and a collecting cylinder, are accelerating and tearing-off cams which grip the incoming product and tear it off from the strand at the residual crosspieces.

Abstract: Compounds of the formula I 1

Abstract: The invention relates to a method for detecting inhibitors or ligands of binding domains, which comprises using a protein which contains at least one catalytic domain and at least one binding domain, incubating said protein with a marker substrate which binds to the catalytic domain of the protein and is converted, with a substrate which can reversibly bind to the catalytic domain and to the binding domain, and with the inhibitor and determining whether the marker substrate is converted by the protein.

Abstract: Compounds of the formula I are suitable for the production of pharmaceuticals for the prophylaxis and therapy of conditions whose course involves an increased activity of matrix-degrading enzymes, in particular stromelysin.

Abstract: Compounds of the formula (I): 1

Abstract: Compounds of the formula I 1

Abstract: Cyclic and heterocyclic N-substituted &agr;-iminohydroxamic and -carboxylic acids

Abstract: A process for producing stainless steels, particularly special steels containing chromium and chromium-nickel, in a smelting arrangement having at least two vessels, for supplying a steel foundry. A charge having mostly iron-containing raw scrap materials and partially carbon-containing alloy carriers is melted in a first vessel. At a temperature of 1460° C., the melt is decarburized by the injection of oxygen so as to reduce the carbon content to less than 0.3%. The melt is heated to a tapping temperature of between 1620° C. to 1720° C. and the carbon content is subsequently reduced to 0.1%. A second charge is melted in a second vessel simultaneously with the decarburizing of the first charge in the first vessel.

Abstract: Compounds of the formula I are suitable for the production of pharmaceuticals for the prophylaxis and therapy of disorders in the course of which an increased activity of matrix-degrading enzymes is involved.

Abstract: Compounds of the formula (I): are suitable for the preparation of pharmaceuticals for prophylaxis and treatment of all those diseases where an increased concentration of interleukin-1&bgr; participates in their course, for example septic shock, leukemia, hepatitis, muscular degeneration, HIV infections or degenerative joint diseases (such as osteoarthrosis, spondylosis, chondrolysis following joint trauma or prolonged immobilization of joints following meniscus or patella injuries, or torn ligaments), diseases of the connective tissue (such as collagenosis, periodontal diseases, or wound-healing disturbances), and chronic diseases of the locomotor system (such as inflammatory or immunologically or metabolism-related acute and chronic arthritis, arthropathies, rheumatoid arthritis, myalgias and disturbances in bone metabolism).

Abstract: Compounds of the formula I are suitable for preparing pharmaceuticals for the treatment of disorders in the course of which is involved an increased activity of matrix-degrading metalloproteinases.

Abstract: Compounds of formula I, ##STR1## and the physiologically tolerable salts thereof, wherein the substituents R.sub.1 -R.sub.4 have the meanings given in the specifications and show an activity against inflammatory conditions.

Abstract: A gripper cylinder for a folding apparatus, the gripper cylinder having a cylinder shaft on which a cylinder body is mounted and at least two gripper stations mounted to the cylinder body. The gripper stations include grippers and corresponding gripper bases. An adjustment mechanism is provided for adjusting the distance between each gripper and its corresponding gripper base to correspond to the thickness of a product to be gripped. The gripper mechanism is operative to simultaneously adjust all of the gripper stations.

Abstract: A light beam deflection unit is formed of a light-transmissive deflection prism extending in the direction of an optical axis and of a carrier prism. The deflection prism has a light entry face oriented essentially perpendicular to the optical axis, a reflection face proceeding obliquely relative to the optical axis and a light exit face. The carrier prism is joined to the deflection prism at the reflection face and supplements the latter to form a composite unit essentially symmetrical relative to the optical axis that is seated rotatable around the optical axis. For the purpose of reducing air turbulence upon rotation of the composite unit, a hollow-cylindrical element whose cylinder axis essentially coincides with the optical axis and whose inside diameter at least corresponds to the diameter of the light beam incident onto the light entry face and that is connected to the composite unit is arranged in front of the light entry face.

Abstract: A compound having the formula (I), a physiologically tolerable salt of the compound having the formula (I) and/or a steroisomeric form of the compound having the formula (I), in which one residue R.sup.1 or R.sup.2 stands for the formula (II), are suitable for preparing medicaments for the therapy of inflammations, asthma, rheumatoid diseases and auto-immune diseases.

Abstract: Compounds of formula I, ##STR1## wherein the substituents R.sub.1 -R.sub.4 and a have the given meanings and show an activity against inflammatory conditions.

Abstract: An apparatus for transporting and a dependable deceleration of folded products, e.g. before being fed to a second longitudinal fold, including two groups of belts, each of which contains upper and lower belts, supplemented by a further belt group containing only upper belts. These belts of the further belt group are guided parallel to the lower belts of the first belt group at a distance which is greater than the product thickness.

Abstract: Lipid-selective antioxidants of the formula I(A).sub.a (L)(X).sub.a, (I),in whichA=an antioxidative component,L=a bridging member,X=a lipophilic componenta and a'=independently of one another the numbers 1 or 2.The compounds are used for the protection of lipid-containing substances against oxidation and in pharmaceuticals for the prophylaxis and treatment of diseases in which bioradicals are involved, in particular of coronary, circulatory and vascular diseases.

Abstract: Lipid-selective antioxidants of the formula I(A).sub.a (L)(X).sub.a, (I),in whichA=an antioxidative component,L=a bridging member,X=a lipophilic componenta and a'=independently of one another the numbers 1 or 2.The compounds are used for the protection of lipid-containing substances against oxidation and in pharmaceuticals for the prophylaxis and treatment of diseases in which bioradicals are involved, in particular of coronary, circulatory and vascular diseases.

Abstract: A system for inerting a casting vessel, such as a traversable ladle or torpedo vessel, used for transporting molten metal, the vessel being positioned below the molten metal outlet opening at a transfer station, and the vessel cavity being flushed with an inert gas both prior to the molten metal inletting and during the inflow of the molten metal in such a manner as to avoid contact between the molten metal surface and the vessel and the atomospheric oxygen. A blowpipe is arranged in the vicinity of the molten metal outlet opening but does not intersect the molten metal stream, is located outside the free space profile of the vessel at least during the approach and return of the vessel, and terminates a distance from the vessel inlet opening and produces at its terminal end an inert gas stream which enters the cavity of the vessel adjacent the molten metal stream at an acute angle.