Patents by Inventor Koichi Matsubara
Koichi Matsubara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11949952Abstract: A television receiver 101 is connected to two or more wireless terminals via a communication line. A controller 214 and a network I/F 212 in the television receiver 101 send pieces of login information entered from the two or more wireless terminals to the content distribution server and obtain pieces of content list information each generated by the content distribution server based on the pieces of login information. An aggregated content list in which the obtained pieces of content list information are aggregated is generated. The display 210 displays the aggregated content list. The content list information includes content available for viewing on the information terminal connected to the communication line. The aggregated content list includes content available for viewing on the two or more information terminals in which the pieces of content list information are aggregated.Type: GrantFiled: March 25, 2022Date of Patent: April 2, 2024Assignee: MAXELL, LTD.Inventors: Masahiro Kageyama, Takashi Matsubara, Koichi Hamada
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Patent number: 11914910Abstract: A non-transitory computer readable medium storing a program causing a computer, which reproduces a color tone of a printed matter and displays the color tone on a screen before printing, to realize a function of acquiring a density value of a color material that develops a color by absorption of a specific wavelength component and a property of paper related to the absorption of the specific wavelength component, and a function of displaying an image that reproduces the color tone of the printed matter based on the density value and the property of the paper.Type: GrantFiled: August 3, 2022Date of Patent: February 27, 2024Assignee: FUJIFILM Business Innovation Corp.Inventors: Koichi Matsubara, Yuichi Nishikuni, Shinya Takaishi, Daichi Kurotsu
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Patent number: 11858987Abstract: An objective of the present invention is to obtain two types of substantively homogeneous cancer stem cell populations which can be characterized using the cell surface marker Lgr5, and to provide cancer therapeutics using an antibody against a cell membrane molecule specifically expressed in these cancer stem cells by identifying said cell membrane molecule. A further objective is to provide, using an antibody against a cell membrane molecule specifically expressed in cancer stem cells, a reagent for detecting cancer stem cells, and a method for diagnosing and sorting cancer patients. The present inventors discovered that highly pure large intestine cancer stem cells (CSC) can be obtained in a large quantity, and identified the two types of conditions of large intestine CSCs distinguishable through Lgr5 expression. Moreover, the present inventors discovered that an antibody against a cell membrane molecule specifically expressed in said cancer stem cells can damage said cells.Type: GrantFiled: June 26, 2020Date of Patent: January 2, 2024Assignee: Chugai Seiyaku Kabushiki KaishaInventors: Tatsumi Yamazaki, Hisafumi Okabe, Shinta Kobayashi, Takeshi Watanabe, Koichi Matsubara, Osamu Natori, Atsuhiko Kato, Masami Suzuki
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Publication number: 20230326080Abstract: A non-transitory computer readable medium storing a program causing a computer, which reproduces a color tone of a printed matter and displays the color tone on a screen before printing, to realize a function of generating an image in which the color tone of the printed matter is reproduced based on a first component reflected by a metallic color material and a second component transmitted through the color material and reflected by paper.Type: ApplicationFiled: August 15, 2022Publication date: October 12, 2023Applicant: FUJIFILM Business Innovation Corp.Inventors: Shinya TAKAISHI, Koichi MATSUBARA, Yuichi NISHIKUNI, Daichi KUROTSU
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Publication number: 20230308593Abstract: A non-transitory computer readable recording medium records program for causing a computer that reproduces an image of a printed matter before printing and displays the image on a screen to implement: a changing function of, in a case where a first image generated according to a density value of a color material and a second image representing a surface of a sheet to be used for printing are combined to generate an image of a printed matter, changing appearance of the second image, according to a total amount of the color material to be used for printing the corresponding first image, for each pixel position.Type: ApplicationFiled: March 3, 2023Publication date: September 28, 2023Applicant: FUJIFILM Business Innovation Corp.Inventors: Daichi KUROTSU, Yuichi Nishikuni, Koichi Matsubara, Shinya Takaishi
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Publication number: 20230305776Abstract: A non-transitory computer readable medium storing a program causing a computer, which reproduces a color tone of a printed matter and displays the color tone on a screen before printing, to realize a function of acquiring a density value of a color material that develops a color by absorption of a specific wavelength component and a property of paper related to the absorption of the specific wavelength component, and a function of displaying an image that reproduces the color tone of the printed matter based on the density value and the property of the paper.Type: ApplicationFiled: August 3, 2022Publication date: September 28, 2023Applicant: FUJIFILM Business Innovation Corp.Inventors: Koichi MATSUBARA, Yuichi NISHIKUNI, Shinya TAKAISHI, Daichi KUROTSU
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Publication number: 20230085803Abstract: An objective of the present invention is to provide non-human animal models of cancer pathology, which mimic the hierarchical organization, cancer progression process, or biological property of human cancer tissues, and uses thereof. To achieve the objective described above, first, the present inventors transplanted cells of NOG-established cancer lines into NOG mice and morphologically observed the resulting tissue organization. As a result, the non-human animal models were demonstrated to exhibit pathologies (the hierarchical organization, cancer progression process, or biological properties of the cancer cells) similar to that of human cancer. Specifically, the present inventors succeeded in preparing non-human animal models exhibiting pathologies more similar to a human cancer, and cell culture systems using NOG-established cancer cell lines where the in vitro cell morphology is more similar to that of human cancer.Type: ApplicationFiled: November 22, 2022Publication date: March 23, 2023Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHAInventors: Masami Suzuki, Koichi Matsubara, Atsuhiko Kato, Chie Kato, Shinta Kobayashi, Yu Jau Chen, Masaki Yamazaki
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Patent number: 11536713Abstract: An objective of the present invention is to provide non-human animal models of cancer pathology, which mimic the hierarchical organization, cancer progression process, or biological property of human cancer tissues, and uses thereof. To achieve the objective described above, first, the present inventors transplanted cells of NOG-established cancer lines into NOG mice and morphologically observed the resulting tissue organization. As a result, the non-human animal models were demonstrated to exhibit pathologies (the hierarchical organization, cancer progression process, or biological properties of the cancer cells) similar to that of human cancer. Specifically, the present inventors succeeded in preparing non-human animal models exhibiting pathologies more similar to a human cancer, and cell culture systems using NOG-established cancer cell lines where the in vitro cell morphology is more similar to that of human cancer.Type: GrantFiled: December 24, 2010Date of Patent: December 27, 2022Assignee: Chugai Seiyaku Kabushiki KaishaInventors: Masami Suzuki, Koichi Matsubara, Atsuhiko Kato, Chie Kato, Shinta Kobayashi, Yu Jau Chen, Masaki Yamazaki
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Patent number: 11124773Abstract: The purpose of the present invention is to provide: a cancer stem cell mass from which cells incapable of forming cancer are substantially removed and which has a characteristic property of reproducing a layered structure of a cancer tissue; a process for producing the cancer stem cell mass; and use of the cancer stem cell mass. For achieving the purpose, the present inventors grew a human cancer tissue repeatedly in a NOG mouse, separated cancer cells from the grown cancer tissue, and made a comparison of various cancer cell culture processes with each other. As a result, a cancer stem cell composition which is homogeneous and is substantially free of the coexistence of cells capable of forming cancer and cells incapable of forming cancer in a mixed state can be produced successively by employing an attached culture process using a serum-free stem cell culture medium rather than a generally employed floating culture process, and consequently the present invention has been accomplished.Type: GrantFiled: October 6, 2011Date of Patent: September 21, 2021Assignee: CHUGAI SEIYAKU KABUSHIKI KAISHAInventors: Tatsumi Yamazaki, Hisafumi Okabe, Shinta Kobayashi, Yu Jau Chen, Atsuhiko Kato, Masami Suzuki, Koichi Matsubara
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Patent number: 10999478Abstract: An image processing apparatus includes a receiver and a correcting unit. The receiver receives a first read value and a second read value. The first read value indicates a result of reading a first color by a reader from a recording medium in which the first color is applied to a first area in which in-plane density unevenness is confirmable within the recording medium. The second read value indicates a result of reading a second color by the reader. The second color is different from the first color and is applied to a second area that is substantially the same as the first area in a superimposed manner. The correcting unit corrects in-plane density unevenness of the second color applied to the first color in the superimposed manner based on the first read value received by the receiver and the second read value received by the receiver.Type: GrantFiled: July 26, 2019Date of Patent: May 4, 2021Assignee: FUJI XEROX CO., LTD.Inventors: Tomohiko Takei, Koichi Matsubara, Yuma Motegi, Kazuhiko Horikawa, Ryosuke Yonesaka
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Patent number: 10934351Abstract: An objective of the present invention is to obtain two types of substantively homogeneous cancer stem cell populations which can be characterized using the cell surface marker Lgr5, and to provide cancer therapeutics using an antibody against a cell membrane molecule specifically expressed in these cancer stem cells by identifying said cell membrane molecule. A further objective is to provide, using an antibody against a cell membrane molecule specifically expressed in cancer stem cells, a reagent for detecting cancer stem cells, and a method for diagnosing and sorting cancer patients. The present inventors discovered that highly pure large intestine cancer stem cells (CSC) can be obtained in a large quantity, and identified the two types of conditions of large intestine CSCs distinguishable through Lgr5 expression. Moreover, the present inventors discovered that an antibody against a cell membrane molecule specifically expressed in said cancer stem cells can damage said cells.Type: GrantFiled: February 12, 2016Date of Patent: March 2, 2021Assignee: CHUGAI SEIYAKU KABUSHIKI KAISHAInventors: Tatsumi Yamazaki, Hisafumi Okabe, Shinta Kobayashi, Takeshi Watanabe, Koichi Matsubara, Osamu Natori, Atsuhiko Kato, Masami Suzuki
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Publication number: 20200385686Abstract: The purpose of the present invention is to provide: a cancer stem cell mass from which cells incapable of forming cancer are substantially removed and which has a characteristic property of reproducing a layered structure of a cancer tissue; a process for producing the cancer stem cell mass; and use of the cancer stem cell mass. For achieving the purpose, the present inventors grew a human cancer tissue repeatedly in a NOG mouse, separated cancer cells from the grown cancer tissue, and made a comparison of various cancer cell culture processes with each other. As a result, a cancer stem cell composition which is homogeneous and is substantially free of the coexistence of cells capable of forming cancer and cells incapable of forming cancer in a mixed state can be produced successively by employing an attached culture process using a serum-free stem cell culture medium rather than a generally employed floating culture process, and consequently the present invention has been accomplished.Type: ApplicationFiled: August 14, 2020Publication date: December 10, 2020Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHAInventors: Tatsumi Yamazaki, Hisafumi Okabe, Shinta Kobayashi, Yu Jau Chen, Atsuhiko Kato, Masami Suzuki, Koichi Matsubara
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Publication number: 20200325222Abstract: An objective of the present invention is to obtain two types of substantively homogeneous cancer stem cell populations which can be characterized using the cell surface marker Lgr5, and to provide cancer therapeutics using an antibody against a cell membrane molecule specifically expressed in these cancer stem cells by identifying said cell membrane molecule. A further objective is to provide, using an antibody against a cell membrane molecule specifically expressed in cancer stem cells, a reagent for detecting cancer stem cells, and a method for diagnosing and sorting cancer patients. The present inventors discovered that highly pure large intestine cancer stem cells (CSC) can be obtained in a large quantity, and identified the two types of conditions of large intestine CSCs distinguishable through Lgr5 expression. Moreover, the present inventors discovered that an antibody against a cell membrane molecule specifically expressed in said cancer stem cells can damage said cells.Type: ApplicationFiled: June 26, 2020Publication date: October 15, 2020Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHAInventors: Tatsumi Yamazaki, Hisafumi Okabe, Shinta Kobayashi, Takeshi Watanabe, Koichi Matsubara, Osamu Natori, Atsuhiko Kato, Masami Suzuki
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Publication number: 20200304689Abstract: An image processing apparatus includes a receiver and a correcting unit. The receiver receives a first read value and a second read value. The first read value indicates a result of reading a first color by a reader from a recording medium in which the first color is applied to a first area in which in-plane density unevenness is confirmable within the recording medium. The second read value indicates a result of reading a second color by the reader. The second color is different from the first color and is applied to a second area that is substantially the same as the first area in a superimposed manner. The correcting unit corrects in-plane density unevenness of the second color applied to the first color in the superimposed manner based on the first read value received by the receiver and the second read value received by the receiver.Type: ApplicationFiled: July 26, 2019Publication date: September 24, 2020Applicant: FUJI XEROX CO., LTD.Inventors: Tomohiko TAKEI, Koichi MATSUBARA, Yuma MOTEGI, Kazuhiko HORIKAWA, Ryosuke YONESAKA
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Patent number: 10675815Abstract: A data processing apparatus includes: a receiving unit that receives first data defining a shape and a color of a three-dimensional object; and a generating unit, wherein when two or more color components interfere with each other in one voxel as a result of performing a halftoning process for each of plural color components based on color information in the first data, the generating unit generates color voxel data by assigning any one of the two or more color components in the first data as color information of the one voxel, using a density ratio of colors corresponding to the two or more color components in the first data.Type: GrantFiled: July 11, 2017Date of Patent: June 9, 2020Assignee: FUJI XEROX CO., LTD.Inventors: Koichi Matsubara, Kenji Hara, Ryosuke Yonesaka
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Patent number: 10632681Abstract: A data processing apparatus includes: a receiving unit: that receives first data defining a shape and a color of a three-dimensional object; and a generating unit, wherein when two or snore color components interfere with each other in one voxel as a result of performing a halftoning process for each of plural color components based on color information in the first data, the generating unit generates color voxel data by assigning any one of the two or more color components as color information of the one voxel and assigning the remaining color components of the two or more color components as color information of voxels present around the one voxel.Type: GrantFiled: July 11, 2017Date of Patent: April 28, 2020Assignee: FUJI XEROX CO., LTD.Inventors: Koichi Matsubara, Kenji Hara, Ryosuke Yonesaka
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Patent number: 10181217Abstract: A data processing apparatus includes a receiving unit that receives first data that defines a shape of and a color of a surface of a three-dimensional object on each specific surface region of the three-dimensional object, and a generating unit that generates color voxel data from the first data. The generating unit assigns plural color components to plural surface voxels in accordance with color information on the color of the surface in the first data, starting with surface voxels, in a priority order of the color components from one having a lower lightness value to another having a higher lightness value, and does not assign an achromatic color component to a surface voxel if a density of the color of the surface in the first data is less than 100 percent.Type: GrantFiled: October 11, 2017Date of Patent: January 15, 2019Assignee: FUJI XEROX CO., LTD.Inventors: Ryosuke Yonesaka, Koichi Matsubara, Kenji Hara
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Patent number: 10018630Abstract: An objective of the present invention is to provide: a cancer stem cell isolated using a cell marker; a substantively homogeneous cancer stem cell population including said cancer stem cell; and a method of preparing said cancer stem cell population. Another objective of the present invention is to provide: a method for separating cancer stem cells with a high proliferative potential and those with a low proliferative potential; a method for inducing cancer stem cells to have a different proliferative potential; and cancer stem cells separated or induced by these separation or induction methods. A further objective of the present invention is to provide: a method of screening for pharmaceuticals using said cancer stem cell or cancer stem cell population; a method for detecting the presence of said cancer stem cell or cancer stem cell population and for identifying or quantifying the same.Type: GrantFiled: September 7, 2012Date of Patent: July 10, 2018Assignees: CHUGAI SEIYAKU KABUSHIKI KAISHA, PHARMALOGICALS RESEARCH PTE. LTD.Inventors: Tatsumi Yamazaki, Hisafumi Okabe, Shinta Kobayashi, Takeshi Watanabe, Koichi Matsubara, Atsuhiko Kato, Masami Suzuki
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Publication number: 20180104899Abstract: A data processing apparatus includes: a receiving unit: that receives first data defining a shape and a color of a three-dimensional object; and a generating unit, wherein when two or snore color components interfere with each other in one voxel as a result of performing a halftoning process for each of plural color components based on color information in the first data, the generating unit generates color voxel data by assigning any one of the two or more color components as color information of the one voxel and assigning the remaining color components of the two or more color components as color information of voxels present around the one voxel.Type: ApplicationFiled: July 11, 2017Publication date: April 19, 2018Applicant: FUJI XEROX CO., LTD.Inventors: Koichi MATSUBARA, Kenji HARA, Ryosuke YONESAKA
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Publication number: 20180108170Abstract: A data processing apparatus includes an accepting unit that accepts first data defining, for each specific surface region, a shape of a three-dimensional object and a color of a surface of the three-dimensional object; and a generating unit that generates color voxel data from the accepted first data, the generating unit generating the color voxel data so that color information indicative of presence of a color is given to inner voxels within a larger depth from a surface voxel in a region of the first data where a density of the color of the surface is higher than in a region of the first data where the density of the color of the surface is lower.Type: ApplicationFiled: May 5, 2017Publication date: April 19, 2018Applicant: FUJI XEROX CO., LTD.Inventors: Koichi MATSUBARA, Kenji HARA, Ryosuke YONESAKA