Abstract: Provided is a tear lipid layer stabilizer that is capable of stabilizing a tear lipid layer and allowing the tear lipid layer to sufficiently spread over a corneal surface, to thereby prevent the evaporation of a tear aqueous layer on the corneal surface, and hence is suitable for amelioration, alleviation, or treatment of evaporative dry eye symptoms caused by Meibomian gland dysfunction, an ophthalmic solution having blended therein the tear lipid layer stabilizer, and a tear lipid layer-stabilizing method using the tear lipid layer stabilizer. The tear lipid layer stabilizer includes a copolymer that has a weight-average molecular weight of from 10,000 to 5,000,000, and contains 10 mol % to 90 mol % of a constituent unit (A) based on 2-(meth)acryloyloxyethyl phosphorylcholine and 90 mol % to 10 mol % of a constituent unit (B) based on an alkyl group-containing (meth)acrylic monomer.

Abstract: Provided by the present invention is a corrigent composed of a copolymer having a weight average molecular weight of 10,000-5,000,000 and comprising 10-90 mol % of a constitution unit based on 2-(meth)acryloyloxyethylphosphoryl choline, and 90-10 mol % of a (meth)acrylic monomer containing an alkyl group, a (meth)acrylic monomer containing a quaternary ammonium group and a constitution unit based on a (meth)acrylamide monomer. The present invention also provides a composition for mouth cavity containing the corrigent.

Abstract: An oral composition for reducing dentinal hypersensitivity according to the present invention comprises a phosphorylcholine-containing polymer as an active ingredient. A general consumer can use the oral composition routinely in various forms. The oral composition is brought into contact with an oral cavity of a user to reduce the dentinal hypersensitivity.

Abstract: An elastic wave device includes a longitudinally-coupled resonator surface acoustic wave filter including first to third IDTs and a parallel trap including a surface acoustic wave resonator. The longitudinally-coupled resonator surface acoustic wave filter is asymmetric with respect to a central axis of the second IDT, the central axis extending in a direction perpendicular or substantially perpendicular to the elastic-wave propagation direction on the piezoelectric substrate. When the duty ratio of an IDT of the surface acoustic wave resonator is denoted by D0 and the duty ratios of the first to third IDTs are respectively denoted by D1 to D3, the duty ratio D0 is between the highest of the duty ratios D1 to D3 and the lowest of the duty ratios D1 to D3.

Abstract: Provided is a tear lipid layer stabilizer that is capable of stabilizing a tear lipid layer and allowing the tear lipid layer to sufficiently spread over a corneal surface, to thereby prevent the evaporation of a tear aqueous layer on the corneal surface, and hence is suitable for amelioration, alleviation, or treatment of evaporative dry eye symptoms caused by Meibomian gland dysfunction, an ophthalmic solution having blended therein the tear lipid layer stabilizer, and a tear lipid layer-stabilizing method using the tear lipid layer stabilizer. The tear lipid layer stabilizer includes a copolymer that has a weight-average molecular weight of from 10,000 to 5,000,000, and contains 10 mol % to 90 mol % of a constituent unit (A) based on 2-(meth)acryloyloxyethyl phosphorylcholine and 90 mol % to 10 mol % of a constituent unit (B) based on an alkyl group-containing (meth)acrylic monomer.

Abstract: A frame member for a vehicle comprises a first side wall, a second side wall provided on an inward side, in a vehicle width direction, of the first side wall, an upper wall and a lower wall, which are configured to form a structure of the closed cross section of the frame member together with the first and the second side walls, an upper-side lateral rib and a lower-side lateral rib, which are respectively provided between the upper and lower walls to interconnect the first and the second side walls and extend linearly, when viewed from the longitudinal direction of the frame member, an upper-side vertical rib provided to face the first side wall and interconnect the upper wall and the upper-side lateral rib, and a lower-side vertical rib provided to face the first side wall and interconnect the lower wall and the lower-side lateral rib.

Abstract: A ladder-type surface acoustic wave filter includes interdigital transducer electrodes disposed on a LiTaO3 piezoelectric substrate, and series resonators and parallel resonators defined by the interdigital transducer electrodes, and utilizes a leaky wave that propagates on the LiTaO3 piezoelectric substrate. A bandwidth ratio indicating a bandwidth of a passband of the ladder-type surface acoustic wave filter is about 2.5% or greater, and a cutoff frequency due to bulk wave radiation of one of the parallel resonators, is in a frequency range higher than the passband.

Abstract: Provided is a drug sustained-releasing medical contact lens in which a component that is water-insoluble and has pharmacological activity is retained to impart drug sustained-releasability, and which is excellent in oxygen permeability. It has been found that a drug sustained-releasing medical contact lens containing a specific amount of each of a silicone-based polymer having a specific structure and a drug having a specific solubility can achieve the above-mentioned contact lens.

Abstract: The release agent composition of the invention contains a rubber elastomer (A) and an acrylic polymer (B) containing a structural unit derived from a long-chain alkyl (meth)acrylate (b1) represented by the following formula (1): wherein R1 represents a hydrogen atom or a methyl group, and R2 represents a branched alkyl group having 10 to 30 carbon atoms.

Abstract: An object of the present invention is to provide: a novel gene (polynucleotide) encoding an FAD-conjugated glucose dehydrogenase having excellent properties that it has excellent reactivity to glucose, excellent thermal stability, and excellent substrate-recognition performance and also has a low activity for maltose; a process for the production of the enzyme using a transformant cell transfected with the gene; and a method for the determination of glucose, a reagent composition for use in the determination of glucose, a biosensor for use in the determination of glucose and others, each characterized by using the enzyme obtained.

Abstract: Provided is a biofilm formation-preventing agent that improves the sustainability of an effect of a drug, and keeps an oral environment satisfactory in a sustainable manner, without an increase in drug concentration or treatment time to prevent the maturation of dental plaque into a biofilm, and a composition for oral use containing the biofilm formation-preventing agent. More specifically, the biofilm formation-preventing agent includes a copolymer having a weight-average molecular weight of from 10,000 to 5,000,000 and containing: 10 mol % to 90 mol % of a constituent unit (A) based on 2-(meth) acryloyloxyethyl phosphorylcholine; and 90 mol % to 10 mol % of at least one kind of constituent unit selected from the group consisting of a constituent unit (B1) based on an alkyl group-containing (meth) acrylic monomer, a constituent unit (B2) based on a quaternary ammonium group-containing (meth) acrylic monomer, and a constituent unit (B3) based on a (meth) acrylamide-based monomer.

Abstract: Provided by the present invention is a corrigent composed of a copolymer having a weight average molecular weight of 10,000-5,000,000 and comprising 10-90 mol % of a constitution unit based on 2-(meth)acryloyloxyethylphosphoryl choline, and 90-10 mol % of a (meth)acrylic monomer containing an alkyl group, a (meth)acrylic monomer containing a quaternary ammonium group and a constitution unit based on a (meth)acrylamide monomer. The present invention also provides a composition for mouth cavity containing the corrigent.

Abstract: An object of the present invention is to provide: a novel gene (polynucleotide) encoding an FAD-conjugated glucose dehydrogenase having excellent properties that it has excellent reactivity to glucose, excellent thermal stability, and excellent substrate-recognition performance and also has a low activity for maltose; a process for the production of the enzyme using a transformant cell transfected with the gene; and a method for the determination of glucose, a reagent composition for use in the determination of glucose, a biosensor for use in the determination of glucose and others, each characterized by using the enzyme obtained.

Abstract: Provided is an ophthalmic solution for treatment or prevention of lid wiper epitheliopathy, which is capable of imparting sufficient lubricity to a corneal surface or a soft contact lens surface. It has been found that the above-mentioned object can be achieved by an ophthalmic solution containing, at a specific ratio, a copolymer having a structure having three kinds of different constituent units at a specific ratio.

Abstract: A release sheet 1 may include a base material 12 and a release agent layer 11 provided on the base material 12. The release agent layer 11 is composed of a cured product of a release agent composition containing 50 mass % or more of a diene-based polymer. Mooney viscosity (ML1+4 (100° C.)) of the diene-based polymer measured at 100° C. according to HS K6300 is in the range of 25 to 70, and a ratio (TCp/ML1+4 (100° C.)) of the Mooney viscosity (ML1+4 (100° C.)) and a viscosity (TCp) of a toluene solution of the diene-based polymer is 2.2 or less. This makes it possible to provide a release sheet which can sufficiently suppress adverse effects on electric components and the like, which has a small dependence of release force on peel rate and which can suppress the occurrence of zipping phenomenon, and a pressure-sensitive adhesive article having such a release sheet.

Abstract: An oral composition for reducing dentinal hypersensitivity according to the present invention comprises a phosphorylcholine-containing polymer as an active ingredient. A general consumer can use the oral composition routinely in various forms. The oral composition is brought into contact with an oral cavity of a user to reduce the dentinal hypersensitivity.

Abstract: This method is a method for manufacturing a gas turbine blade, including: producing a gas turbine blade having a cooling pass inside thereof; and partially coating an inner surface of the cooling pass with Al. The step of partially coating an inner surface of the cooling pass with Al further including: a first step of specifying a temperature range which satisfies both of oxidation resistance and fatigue strength and the temperature distribution of the inner surface of the cooling pass based on an examination result or result of a numerical analysis; a second step of setting an Al-coating-applying portion of the inner surface of the cooling pass as the temperature range specified at the first step; and a third step of applying Al coating only into the set Al-coating-applying portion.

Abstract: An object of the present invention is to provide: a novel gene (polynucleotide) encoding an FAD-conjugated glucose dehydrogenase having excellent properties that it has excellent reactivity to glucose, excellent thermal stability, and excellent substrate-recognition performance and also has a low activity for maltose; a process for the production of the enzyme using a transformant cell transfected with the gene; and a method for the determination of glucose, a reagent composition for use in the determination of glucose, a biosensor for use in the determination of glucose and others, each characterized by using the enzyme obtained.

Abstract: An object of the present invention is to provide: a novel gene (polynucleotide) encoding an FAD-conjugated glucose dehydrogenase having excellent properties that it has excellent reactivity to glucose, excellent thermal stability, and excellent substrate-recognition performance and also has a low activity for maltose; a process for the production of the enzyme using a transformant cell transfected with the gene; and a method for the determination of glucose, a reagent composition for use in the determination of glucose, a biosensor for use in the determination of glucose and others, each characterized by using the enzyme obtained.