Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.

Abstract: Provided is a boron nitride sintered body having a porous structure, the boron nitride sintered body including a lump particle formed by aggregation of primary particles of boron nitride and having a particle diameter of 15 ?m or more. Provided is a method for manufacturing a boron nitride sintered body, the method including: a nitriding step of firing a raw material powder containing boron carbide in an atmosphere containing nitrogen to obtain a fired product including lump particles each having a core part with primary particles of boron carbonitride aggregated and a shell part surrounding the core part; and a firing step of molding and heating a blend containing the fired product including lump particles and a sintering aid to obtain the boron nitride sintered body having a porous structure and including lump particles of boron nitride.

Abstract: Provided is a boron nitride sintered body including: a plurality of coarse particles each having a length of 20 ?m or more; and fine particles smaller than the plurality of coarse particles, in which, when viewed in a cross-section, the plurality of coarse particles intersect with each other. Provided is a method for manufacturing a boron nitride sintered body, the method including: a raw material preparation step of firing a mixture containing boron carbonitride and a boron compound in a nitrogen atmosphere to obtain lump boron nitride having an average particle diameter of 10 to 200 ?m; and a sintering step of molding and heating a blend containing the lump boron nitride and a sintering aid to obtain a boron nitride sintered body including coarse particles each having a length of 20 ?m or more in a cross-section and fine particles smaller than the coarse particles.

Abstract: Provided is a method for manufacturing a composite body, the method including: a nitriding step of firing a boron carbide powder in a nitrogen atmosphere to obtain a fired product containing boron carbonitride; a sintering step of molding and heating a blend containing the fired product and a sintering aid to obtain a boron nitride sintered body including boron nitride particles and pores; and an impregnating step of impregnating the boron nitride sintered body with a resin composition, the composite body having the boron nitride sintered body and a resin filled in at least some of the pores of the boron nitride sintered body.

Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.

Abstract: Provided is a boron nitride sintered body including boron nitride particles and pores, the boron nitride sintered body having a sheet shape and a thickness of less than 2 mm. Provided is a method for manufacturing a boron nitride sintered body, the method including a sintering step of molding and heating a blend containing a boron carbonitride powder and a sintering aid to obtain a sheet-shaped boron nitride sintered body including boron nitride particles and pores, in which a thickness of the boron nitride sintered body obtained in the sintering step is less than 2 mm.

Abstract: A bonded substrate includes a substrate, a metal plate forming a stacked state with the substrate, and bonding member. The metal plate has a first surface on the substrate side and a second surface opposite; wherein an edge of the first surface is located outside an edge of the second. The bonding member is disposed between the substrate and plate to bond the plate and substrate, and protrudes from the edge over an entire periphery of the plate. In cut surfaces obtained by cutting the bonded substrate, a peripheral surface length (A) from a portion corresponding to a peripheral edge of the first surface to a corresponding portion of the second, protrusion length of the bonding member, and thickness (C) of the metal plate satisfy first and second expressions. 0.032?B/(A+B)?0.400??(First Expression) 0.5(mm)?C?2.

Abstract: A ceramic-copper composite having a flat plate shape, including: a ceramic layer; a copper layer; and a brazing material layer present between the ceramic layer and the copper layer, in which a specified Expression (1) is satisfied in a cut surface of the copper layer obtained when the ceramic-copper composite is cut at a plane perpendicular to a main surface of the ceramic-copper composite, where S(102)% is an area ratio occupied by copper crystals having a crystal orientation of which an inclination from a crystal orientation of (102) plane is within 10°, S(101)% is an area ratio occupied by copper crystals having a crystal orientation of which an inclination from a crystal orientation of (101) plane is within 10°, S(111)% is an area ratio occupied by copper crystals having a crystal orientation of which an inclination from a crystal orientation of (111) plane is within 10°, and S(112)% is an area ratio occupied by copper crystals having a crystal orientation of which an inclination from a crystal orientati

Abstract: A silicon nitride substrate includes silicon nitride and magnesium, in which when a surface of the silicon nitride substrate is analyzed with an X-ray fluorescence spectrometer under the specific Condition I, XB/XA is 0.8 or more and 1.0 or less.

Abstract: A scribe line is formed on a first surface of a nitride ceramic base material by a laser. Next, the nitride ceramic base material is divided along the scribe line. The scribe line includes a plurality of recessed portions. The plurality of recessed portions are formed in a row on the first surface of the nitride ceramic base material. A depth of each of the plurality of recessed portions is equal to or greater than 0.70 times and equal to or smaller than 1.10 times an opening width of each of the plurality of recessed portions. The opening width of each of the plurality of recessed portions is equal to or greater than 1.00 times and equal to or smaller than 1.10 times an inter-center distance of the plurality of recessed portions.

Abstract: A ceramic green sheet including a plurality of substrate forming regions. A barcode or a two-dimensional code is drawn in a portion of the ceramic green sheet. The barcode or the two-dimensional code is obtained by encoding one or more of the following information. Information relating to raw materials used when the ceramic green sheet is produced, information relating to molding conditions of the ceramic green sheet, information relating to a release agent used when a plurality of the ceramic green sheets are stacked, or a serial number.

Abstract: Provided is a powder fuel supply apparatus comprising a distributor (84) that branches supplied powder fuel to a plurality of branch tubes (82), a plurality of burners (126a) connected to downstream ends (82a) of the plurality of branch tubes (82), respectively, to supply char into a gasification furnace that gasifies the powder fuel, a flow nozzle (85) provided in each of the plurality of branch tubes (82), to apply pressure loss to char flow in the branch tube (82), a differential pressure gauge (86) that measures a differential pressure generated by the flow nozzle (85), and a control unit that determines decrease in flow velocity of the char flow based on the differential pressure obtained by the differential pressure gauge (86).

Abstract: A method for manufacturing a single sheet-type green sheet includes a transporting step of transporting a strip-shaped green sheet that contains ceramic along a longitudinal direction thereof, and an irradiation step of irradiating the transported strip-shaped green sheet with a laser beam to cut the strip-shaped green sheet, thereby obtaining a single sheet-type green sheet.

Abstract: A bonded substrate includes a substrate, a metal plate forming a stacked state with the substrate, and bonding member. The metal plate has a first surface on the substrate side and a second surface opposite; wherein an edge of the first surface is located outside an edge of the second. The bonding member is disposed between the substrate and plate to bond the plate and substrate, and protrudes from the edge over an entire periphery of the plate. In cut surfaces obtained by cutting the bonded substrate, a peripheral surface length (A) from a portion corresponding to a peripheral edge of the first surface to a corresponding portion of the second, protrusion length of the bonding member, and thickness (C) of the metal plate satisfy first and second expressions. 0.032?B/(A+B)?0.400??(First Expression) 0.5 (mm)?C?2.

Abstract: A ceramic-copper composite having a flat plate shape, including: a ceramic layer; a copper layer; and a brazing material layer present between the ceramic layer and the copper layer. When a region having a length of 1,700 ?m in a long-side direction is a region P on a cut surface of the ceramic-copper composite obtained when the ceramic-copper composite is cut with a plane perpendicular to a main surface of the ceramic-copper composite, an average crystal grain size D1 of copper crystals at least partially present in a region P1 within 50 ?m on a side of the copper layer from an interface between the ceramic layer and the brazing material layer in the region P is 30 ?m or more and 100 ?m or less.

Abstract: An object of the present invention is to provide a pulverized coal drying system for a pulverizer, a pulverized coal drying method therefor, a pulverized coal drying program, a pulverizer, and an integrated gasification combined cycle capable of stably drying a carbonaceous feedstock irrespective of the type of the carbonaceous feedstock to be used. There is provided a controller (50) of a pulverizer (10) that dries a supplied carbonaceous feedstock by using a drying fluid and includes a flow rate controller that controls the flow rate of the drying fluid within upper and lower limits of the flow rate of the drying fluid that are set to dry a plurality of types or the carbonaceous feedstock having different moisture contents in such a way that the temperature of the drying fluid discharged from the pulverizer (10) approaches a target temperature.

Abstract: The object is to provide a powder fuel feed apparatus, a gasifier unit, and an integrated gasification combined cycle and a control method of a powder fuel feed apparatus that can suppress deformation of a sintered metal filter with simple and inexpensive configuration. An embodiment includes: a distributor pipe (89) in which a mixed gas containing moisture and a gas in which pulverized coal and nitrogen transported with the pulverized coal are mixed is transported; and a diluting nitrogen system (90) that, when a flow velocity of the mixed gas is less than a predetermined threshold, additionally supplies a diluting nitrogen to a mixing chamber (97) connected to the distributor pipe (89) and forming a part of the distributor pipe (89), and the diluting nitrogen system (90) continuously supplies a predetermined flow rate of the diluting nitrogen to the mixing chamber (97).

Abstract: A pressurizing nozzle includes a nozzle body; a filter that is provided to be perpendicular to the central axis direction of the nozzle body so as to cover the internal cross section of the nozzle body at the leading end portion on one end of the nozzle body and that is made of sintered metal having a prescribed thickness in the central axis direction; a retainer having an annular shape that is mounted to the leading end portion of the nozzle body so as to be disassemble and that fixes the outer circumferential portion of the filter via a pair of sealing parts; and a sealing portion that is disposed along the outer circumferential end face of the filter and that seals a fluid from flowing from the outer circumferential face toward the outside in the radial direction through the filter.

Abstract: A char discharge unit is for discharging char discharged from a filtration unit into a char storage unit in which a pressure is at least temporarily higher pressure than that in the filtration unit. The char discharge unit includes a char discharge line connected to a lower side of the filtration unit in a vertical direction and connected to the char storage unit; a lock hopper installed at an intermediary point of the char discharge line to temporarily store the char; an admission valve installed in the char discharge line between the lock hopper and the filtration unit; a control valve installed in the char discharge line between the lock hopper and the char storage unit; and a control device configured to close the control valve when the admission valve is open, and to close the admission valve when the control valve is open.