Abstract: A developing roll for use in an image-forming apparatus using electrophotography includes a cylindrical core made of metal; an annular elastic layer made of rubber and arranged around the core; and an annular surface layer arranged around the elastic layer. The surface layer includes a central portion and end portions. The central portion is located at the center of the developing roll in the longitudinal direction, the end portions are located at opposite end portions of the developing roll in the longitudinal direction. A coefficient of kinetic friction of the outer peripheral surface of each end portion of the surface layer is less than or equal to 0.1, and a ten-point average roughness Rz of the outer peripheral surface of each end portion of the surface layer is less than or equal to 1.8 ?m.

Abstract: A medical diagnosis support device of an embodiment includes processing circuitry. The processing circuitry acquires first reference data based on first clinical data relating to a diagnosis result of an evaluation target and second reference data based on second clinical data relating to a comparison target diagnosis result for the evaluation target and performs an analysis process relating to the diagnosis result of the evaluation target based on the first reference data and the second reference data. The first reference data includes first data that has been referred to by a first user to obtain the diagnosis result of the evaluation target and second data that has been referred to by a diagnosis support system to obtain the diagnosis result of the evaluation target. The second reference data includes the first data that has been referred to by at least one of the first user and a second user different from the first user in order to obtain the diagnosis result of the comparison target.

Abstract: A developing roll has a metal core, an elastic layer, and a surface layer. A value X is 65.6 N/mm3 or more and a value Y is 229 ?m or more. The value X is P1/(D1×A)?P2/(D2×A). P1 is the load to displace the roll 100 ?m when a metal probe is pressed against the roll. D1 is the displacement of the roll caused by the probe under the load P1. A is the area of the probe. P2 is the load to displace a material roll by 100 ?m when the probe presses against the material roll with the core and the elastic layer and without the surface layer. D2 is the displacement of the material roll caused by the probe under the load P2. The value Y is the displacement of the roll when the probe pierces the surface layer.

Abstract: An electrophotographic photoreceptor includes a conductive substrate, and a lamination type photosensitive layer disposed on the conductive substrate and including a charge generation layer and a charge transport layer, in which the charge transport layer contains a charge transport material, at least one of a polyester resin (PEz) or a polycarbonate resin (PCz) that has at least one of a structure (Z1) represented by Formula (Z1) or a structure (Z2) represented by Formula (Z2) at at least one terminal, and a resin (X) that has at least one of a unit (X1) represented by Formula (X1) or a unit (X2) represented by Formula (X2), a mass proportion of the resin (X) in a total amount of the polyester resin (PEz), the polycarbonate resin (PCz), and the resin (X) in the charge transport layer is 0.

Abstract: A developing roll used in an electrophotographic image forming apparatus has a metal core member, an elastic layer made of a rubber disposed around the core member, and a surface layer disposed around the elastic layer. The texture aspect ratio of the surface Str of the surface layer is equal to or greater than 0.55.

Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.

Abstract: A compound indicated by formula (I) or a pharmacologically acceptable salt thereof is provided as a compound that can be a therapeutic or prophylactic drug for TRPC6-related diseases, such as nephrotic syndrome, membranous nephropathy, acute renal failure, septicemia, chronic renal failure, diabetic nephropathy, pulmonary hypertension, acute lung injury, heart failure, malignant tumor, and muscular dystrophy. (In the formula, Ar1, Ar2, X1-X3, R1, R3, R7, R8, L1, and L2 are as defined in the specifications.

Abstract: A storage apparatus configures a second transfer unit of data based on a zHL read request from a transfer unit of data based on a fiber connect read request, calculates a warranty code for the data of the second transfer unit, stores the data and the warranty code in a memory; after receiving a read request based on zHL, transfers the data together with the warranty code to a host computer if it is determined that the data of the second transfer unit, which is a target of the read request, exists in the memory; and sends a notice of an error of the read request to the host computer when the data of the second transfer unit, which is the target of the read request based on zHL, does not exist in the memory, wherein the host computer which has received the notice outputs a read request.

Abstract: A storage apparatus configures a second transfer unit of data based on a zHL read request from a transfer unit of data based on a fiber connect read request, calculates a warranty code for the data of the second transfer unit, stores the data and the warranty code in a memory; after receiving a read request based on zHL, transfers the data together with the warranty code to a host computer if it is determined that the data of the second transfer unit, which is a target of the read request, exists in the memory; and sends a notice of an error of the read request to the host computer when the data of the second transfer unit, which is the target of the read request based on zHL, does not exist in the memory, wherein the host computer which has received the notice outputs a read request.

Abstract: The purpose of the present invention is to provide a compound that has excellent CDK4/6 inhibitory activity. The present invention is a compound represented by formula (I) or a pharmaceutically acceptable salt of the compound.

Abstract: A port injection valve injects fuel into an intake passage. A base injection amount is an injection amount proportional to an amount of fresh air introduced into a cylinder of an internal combustion engine. A division process involves dividing the base injection amount into a synchronous injection amount and an asynchronous injection amount. In an intake-synchronous injection, the fuel is injected in synchronization with a period in which an intake valve is open. In an intake-asynchronous injection, the fuel is injected at a time advanced with respect to the intake-synchronous injection. In a selective correction process, the asynchronous injection amount is corrected according to a required correction amount for the base injection amount, and the synchronous injection amount is not corrected.

Abstract: A compound, represented by the following formula or a medically acceptable salt thereof, having an effect of regulating the activity of an androgen receptor. In the formula, X represents S, O; Z represents (Ra)n-A-(CR13R14)0-1—(CR11R12)0-1; A represents aryl, heteroaryl; R1 represents alkyl, cycloalkyl, alkenyl, alkynyl, alkoxyalkyl, aryl, arylalkyl, heterocycle, heterocyclic alkyl; R2 represents hydrogen, halogen, alkyl, cycloalkyl, phenyl; R3 represents hydrogen, halogen, alkyl, cycloalkyl, alkoxyalkyl, alkenyl, alkynyl, cycloalkenyl, aryl, arylalkyl, heterocycle, heterocyclic alkyl, acyl, cycloalkylcarbonyl, benzoyl, spiroalkyl, adamantyl, silyl, R31R32NCO—; R4 and R5 represent hydrogen, halogen, alkyl, phenyl, and cycloalkyl.

Abstract: In a head-up display device, in accordance with lifting and lowering operations of a combiner, each protrusion of a combiner support moves along a guide portion, causing a cover-operation member to turn about a rotary axis in a direction in which a cover is opened or closed. The guide portion includes, from top in order: a first guide portion which engages with the protrusion in a first state (use state); a second guide portion which engages with the protrusion when the cover-operation member turns; and a third guide portion which engages with the protrusion in a second state (non-use state). The angle formed by the direction in which the first guide portion extends and the direction in which the third guide portion extends is less than the angle formed by the direction in which the first guide portion extends and the direction in which the second guide portion extends.

Abstract: The purpose of the present invention is to provide a compound that has excellent CDK4/6 inhibitory activity. The present invention is a compound represented by formula (I) or a pharmaceutically acceptable salt of the compound.

Abstract: A vehicle brake hydraulic pressure control apparatus includes a base body and a solenoid valve. The solenoid valve is attached to an attachment hole which opens on one surface of the base body. A plurality of press-fitting portions that are press-fitted to an inner peripheral surface of the attachment hole are provided on an outer peripheral surface of the solenoid valve at an interval in a hole axis direction. Contact lengths, in the hole axis direction, between the inner peripheral surface of the attachment hole and two of the press-fitting portions are different from each other.

Abstract: A port injection valve injects fuel into an intake passage. A base injection amount is an injection amount proportional to an amount of fresh air introduced into a cylinder of an internal combustion engine. A division process involves dividing the base injection amount into a synchronous injection amount and an asynchronous injection amount. In an intake-synchronous injection, the fuel is injected in synchronization with a period in which an intake valve is open. In an intake-asynchronous injection, the fuel is injected at a time advanced with respect to the intake-synchronous injection. In a selective correction process, the asynchronous injection amount is corrected according to a required correction amount for the base injection amount, and the synchronous injection amount is not corrected.

Abstract: In a head-up display device, in accordance with lifting and lowering operations of a combiner, each protrusion of a combiner support moves along a guide portion, causing a cover-operation member to turn about a rotary axis in a direction in which a cover is opened or closed. The guide portion includes, from top in order: a first guide portion which engages with the protrusion in a first state (use state); a second guide portion which engages with the protrusion when the cover-operation member turns; and a third guide portion which engages with the protrusion in a second state (non-use state). The angle formed by the direction in which the first guide portion extends and the direction in which the third guide portion extends is less than the angle formed by the direction in which the first guide portion extends and the direction in which the second guide portion extends.

Abstract: A compound, represented by the following formula or a medically acceptable salt thereof, having an effect of regulating the activity of an androgen receptor. In the formula, X represents S, O; Z represents (Ra)n-A- (CR13R14)0-1—(CR11R12)0-1; A represents aryl, heteroaryl; R1 represents alkyl, cycloalkyl, alkenyl, alkynyl, alkoxyalkyl, aryl, arylalkyl, heterocycle, heterocyclic alkyl; R2 represents hydrogen, halogen, alkyl, cycloalkyl, phenyl; R3 represents hydrogen, halogen, alkyl, cycloalkyl, alkoxyalkyl, alkenyl, alkynyl, cycloalkenyl, aryl, arylalkyl, heterocycle, heterocyclic alkyl, acyl, cycloalkylcarbonyl, benzoyl, spiroalkyl, adamantyl, silyl, R31R32NCO—; R4 and R5 represent hydrogen, halogen, alkyl, phenyl, and cycloalkyl.

Abstract: The purpose of the present invention is to provide a compound having an excellent CDK4/6 inhibiting activity. The present invention is a compound represented by general formula (I) or a pharmaceutically acceptable salt thereof.

Abstract: A fixing apparatus configured to fix a coloring material attached to a recording medium by heating the recording medium by using a fixing member includes: a heater configured to heat the fixing member; an AC power source configured to apply AC voltage to the heater; a temperature detection unit configure to detect a temperature of the heater; and a power control unit configured to control drive power supplied to the heater from the AC power source by calculating an application pattern of AC voltage to be applied to the heater based on an output of the temperature detection unit, and by appropriately selecting a half wave of AC waveform from the AC power source based on the application pattern, wherein the power control unit supplies power equivalent to a waveform with a predetermined phase angle on a non-selected half wave from the AC power source to the heater.