Abstract: The purpose of the present invention is to provide a compound having an excellent CDK4/6 inhibiting activity. The present invention is a compound represented by general formula (I) or a pharmaceutically acceptable salt thereof.

Abstract: An image formation apparatus comprising: a belt member suspended by a plurality of supporting rotating bodies and thus rotating; a cleaning member removing toner adhering to the belt member; a tray receiving waste toner removed from the belt member by the cleaning member; a vibration mechanism vibrating the tray to move the waste toner toward a lower side of the tray; a steering control mechanism to perform movement control to move the belt member in an axial direction of the supporting rotating bodies while the belt member rotates; and a vibration adjustment mechanism to change a manner of vibration of the vibration mechanism, based on the movement control by the steering control mechanism.

Abstract: An image formation apparatus comprising: a belt member suspended by a plurality of supporting rotating bodies and thus rotating; a cleaning member removing toner adhering to the belt member; a tray receiving waste toner removed from the belt member by the cleaning member; a vibration mechanism vibrating the tray to move the waste toner toward a lower side of the tray; a steering control mechanism to perform movement control to move the belt member in an axial direction of the supporting rotating bodies while the belt member rotates; and a vibration adjustment mechanism to change a manner of vibration of the vibration mechanism, based on the movement control by the steering control mechanism.

Abstract: When changing the turn-on/off patterns, a controller of a fixing device sets a control interval of the turn-on/off pattern so as to be longer than a first period of time that does not exert any influence to a flicker value and to be shorter than a second period of time that does not exert any influence to a response to temperature control. The controller of the fixing device selects a third turn-on/off pattern in which power difference between power of a first turn-on/off pattern before the change in the turn-on/off pattern and power of a second turn-on/off pattern after the change in the turn-on/off pattern is smaller than a set reference power difference.

Abstract: A sheet humidification apparatus includes a detect sensor that detects a position of a sheet which is being conveyed; a humidifier that changes a humidification amount and humidifies the sheet; and a controller that controls the humidifier such that a first region on a front end side of the sheet in a conveyance direction is humidified with a first humidification amount, and a second region of the sheet other than the first region is humidified with a second humidification amount larger than the first humidification amount in accordance with a position of the sheet detected by the detect sensor.

Abstract: A fixing apparatus configured to fix a coloring material attached to a recording medium by heating the recording medium by using a fixing member includes: a heater configured to heat the fixing member; an AC power source configured to apply AC voltage to the heater; a temperature detection unit configure to detect a temperature of the heater; and a power control unit configured to control drive power supplied to the heater from the AC power source by calculating an application pattern of AC voltage to be applied to the heater based on an output of the temperature detection unit, and by appropriately selecting a half wave of AC waveform from the AC power source based on the application pattern, wherein the power control unit supplies power equivalent to a waveform with a predetermined phase angle on a non-selected half wave from the AC power source to the heater.

Abstract: A sheet humidification apparatus includes a detect sensor that detects a position of a sheet which is being conveyed; a humidifier that changes a humidification amount and humidifies the sheet; and a controller that controls the humidifier such that a first region on a front end side of the sheet in a conveyance direction is humidified with a first humidification amount, and a second region of the sheet other than the first region is humidified with a second humidification amount larger than the first humidification amount in accordance with a position of the sheet detected by the detect sensor.

Abstract: The present invention relates to a novel compound having a function of inhibiting ROR? activity. The present invention also relates to pharmaceutical composition comprising the compound, a use of the compound in treating or preventing autoimmune diseases, inflammatory diseases, metabolic diseases, or cancer diseases.

Abstract: A fixing apparatus included in an image forming apparatus includes a fixing heater that performs heat fixing, a control unit that controls the fixing heater based on control patterns, a temperature sensor that detects temperature of the fixing heater, and a voltage detection unit that detects a voltage that is applied to the fixing heater. In each control pattern, turn-on period of the fixing heater and turn-off period of the fixing heater are set according to a control cycle of a half cycle duty control. The control unit controls the switching unit to turn on or off the fixing heater using a combination of the control patterns each satisfying a standard for preventing a flicker during each control period of time that is integral multiplication of the control cycle according to the temperature of the fixing heater and the voltage value allied to the fixing heater.

Abstract: When changing the turn-on/off patterns, a controller of a fixing device sets a control interval of the turn-on/off pattern so as to be longer than a first period of time that does not exert any influence to a flicker value and to be shorter than a second period of time that does not exert any influence to a response to temperature control. The controller of the fixing device selects a third turn-on/off pattern in which power difference between power of a first turn-on/off pattern before the change in the turn-on/off pattern and power of a second turn-on/off pattern after the change in the turn-on/off pattern is smaller than a set reference power difference.

Abstract: An image forming apparatus is provided with a fixing unit in which flickers can be effectively reduced while inhibiting electric current imbalance. The fixing unit comprises a fixing heater, a switching unit for switching the fixing heater on/off with an AC power source, and a control unit which controls the switching unit to switch in units of the half wave period of the AC power source AC, and a storing unit for storing a plurality of energization patterns which define the ways of performing the switch control. Each energization pattern corresponds to a control cycle which contains a three or more odd number of the half wave periods each of which is either an OFF period and an ON period, and all the half wave periods of the smaller in number of the ON periods and the OFF periods are not successively arranged.

Abstract: The present invention relates to a novel compound having a function of inhibiting ROR? activity. The present invention also relates to pharmaceutical composition comprising the compound, a use of the compound in treating or preventing autoimmune diseases, inflammatory diseases, metabolic diseases, or cancer diseases.

Abstract: A fixing apparatus included in an image forming apparatus includes a fixing heater that performs heat fixing, a control unit that controls the fixing heater based on control patterns, a temperature sensor that detects temperature of the fixing heater, and a voltage detection unit that detects a voltage that is applied to the fixing heater. In each control pattern, turn-on period of the fixing heater and turn-off period of the fixing heater are set according to a control cycle of a half cycle duty control. The control unit controls the switching unit to turn on or off the fixing heater using a combination of the control patterns each satisfying a standard for preventing a flicker during each control period of time that is integral multiplication of the control cycle according to the temperature of the fixing heater and the voltage value allied to the fixing heater.

Abstract: An image forming apparatus having: an endless fixing belt; a heating member heating the fixing belt; a support member maintaining the fixing belt substantially circular; a pressing member in contact with the fixing belt to form a fixing nip portion; a temperature sensor; a position detector; a storage storing temperatures and positions of the fixing belt detected by the temperature sensor and the position detector; and a control unit. The control unit is operable in a characteristic storing mode and in a fixing mode. In the characteristic storing mode, temperatures of the fixing belt associated with positions are detected, and the detected temperatures and positions are stored in the storage. In the fixing mode, temperatures of the fixing nip portion are predicted with reference to the temperatures and positions stored in the storage, and the heating member is controlled such that the predicted temperatures become a target temperature.

Abstract: A fixing device for fixing an unfixed toner image on a recording sheet by passing the recording sheet through a fixing nip and applying heat and pressure to the recording sheet, the fixing device comprising: a heater including a resistance heater part and a supporting member, the resistance heater part having a positive resistance-temperature characteristic in a temperature range above a predetermined level, and the supporting member being insulative and supporting the resistance heater part such that the resistance heater part applies heat to the recording sheet; a current detector detecting a current supplied to the resistance heater part; and an abnormality determiner determining whether the resistance heater part has an abnormality, based on an initial current detected by the current detector at a predetermined time after a beginning of power supply to the resistance heater part and before the temperature of the resistance heater part reaches the predetermined level.

Abstract: A heater control device that performs phase control of AC power and supplies phase-controlled power to a heater, the heater control device including: a control unit configured to, in the phase control, gradually increase an on-duty ratio until a target power amount is supplied to the heater; and a judgment unit configured to judge whether or not the on-duty ratio is within a predetermined range of on-duty ratios including a 50% on-duty ratio. The control unit (i) increases the on-duty ratio by a first amount while the on-duty ratio is within the predetermined range, and (ii) increases the on-duty ratio by a second amount while the on-duty ratio is not within the predetermined range. The first amount is greater than the second amount.

Abstract: The present invention relates to compounds of the formula and pharmaceutically acceptable salts, solvates or tautomers thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds, and the uses of such compounds, in particular for the treatment of pain.

Abstract: An image forming apparatus is provided with a fixing unit in which flickers can be effectively reduced while inhibiting electric current imbalance. The fixing unit comprises a fixing heater, a switching unit for switching the fixing heater on/off with an AC power source, and a control unit which controls the switching unit to switch in units of the half wave period of the AC power source AC, and a storing unit for storing a plurality of energization patterns which define the ways of performing the switch control. Each energization pattern corresponds to a control cycle which contains a three or more odd number of the half wave periods each of which is either an OFF period and an ON period, and all the half wave periods of the smaller in number of the ON periods and the OFF periods are not successively arranged.

Abstract: A vehicle brake hydraulic pressure control apparatus includes a base body and a solenoid valve. The solenoid valve is attached to an attachment hole which opens on one surface of the base body. A plurality of press-fitting portions that are press-fitted to an inner peripheral surface of the attachment hole are provided on an outer peripheral surface of the solenoid valve at an interval in a hole axis direction. Contact lengths, in the hole axis direction, between the inner peripheral surface of the attachment hole and two of the press-fitting portions are different from each other.

Abstract: An apparatus for multi-energy tissue quantification includes an x-ray imaging system comprises an x-ray source configured to emit a beam of x-rays toward an object to be imaged, a detector configured to receive the x-rays attenuated by the object, and a data acquisition system (DAS) operably coupled to the detector. A computer operably connected to the x-ray source and the DAS is programmed to cause the x-ray source to emit x-rays at each of a first kVp and a second kVp toward the detector, acquire x-ray data from x-rays emitted at the first and second kVp through a region of interest (ROI), and perform a first multi-material decomposition based on the acquired x-ray data. The computer is also programmed to quantify a volume fraction of a first material in the ROI based on the first multi-material decomposition and display the volume fraction of the first material to a user.