Abstract: The present disclosure relates to compositions, methods of making, and methods of using a modified silk-based composition having a selectively tunable hydrophobicity. The provided compositions include silk fibroin having a haloalkyl substituent. The haloalkyl substituent is coupled to an amino acid of the silk fibroin though a linking agent.

Abstract: A non-transitory computer readable medium (107, 127) stores instructions readable and executable by at least one electronic processor (101, 113) to: retrieve, based on a query for a current service case, a plurality of the historical service case records (130) for historical service cases; rank the retrieved historical case service records to generate a ranked list (134) of historical service cases; extract service actions from the historical service case records for the ranked list of historical cases; recommend a plurality of recommended service actions for the current service case based on the service actions extracted from the historical service case records for the ranked list of historical service cases; and display, on a display device (105) of a remote electronic processing device (102) operable by a service engineer, a user interface (UI) (136) having user-selectable windows for displaying the ranked list of historical service cases and the recommended service actions.

Abstract: The present application provides methods for preparing soluble lipidated ligand agents comprising a ligand entity and a lipid entity, and in some embodiments, provides relevant parameters of each of these components, thereby enabling appropriate selection of components to assemble active agents for any given target of interest.

Abstract: The present disclosure relates to, among other things, compositions and methods for treating an inflammatory condition including, but not limited to, ocular inflammation, dry eye disease, and ocular neuropathic pain. One aspect of the present disclosure relates to a composition comprising (a) chemerin or a fragment or analog thereof and (b) a lipid entity linked to the chemerin or fragment or analog thereof.

Abstract: The present application provides methods for preparing soluble lipidated ligand agents comprising a ligand entity and a lipid entity, and in some embodiments, provides relevant parameters of each of these components, thereby enabling appropriate selection of components to assemble active agents for any given target of interest.

Abstract: The present disclosure relates to, among other things, compositions and methods for treating an inflammatory condition including, but not limited to, ocular inflammation, dry eye disease, and ocular neuropathic pain. One aspect of the present disclosure relates to a composition comprising (a) chemerin or a fragment or analog thereof and (b) a lipid entity linked to the chemerin or fragment or analog thereof.

Abstract: Techniques for notifying parent accounts of problematic interactions by teens is described. For example, a social networking system may receive, from a first account, an indication of a problematic interaction. Based at least in part on receiving the indication, the social networking system may cause presentation, to the first account, of a prompt to notify a second account associated with the first account of the interaction. Based at least in part on receiving a confirmation from the first account, the social networking system may then send, to the second account, a notification of the problematic interaction.

Abstract: Techniques enabling accounts of a social networking system to monitor online interactions by supervised accounts across multiple platforms are described. For example, a social networking system (SNS) may receive, from a first account, a request to invite a second account to join a Family Center (FC) so the FC includes data associated with first and second platforms of the SNS. The SNS may receive, from the second account, an indication to accept the request to join the FC associating the first and second accounts via the FC. In some examples, the SNS may receive, from the second account, a request to access the FC. Based on receiving the request to access the FC, the SNS may cause presentation to the second account of interaction data associated with interactions between the first account and the first platform of the SNS and the first account and the second platform of the SNS.

Abstract: Techniques for notifying parent accounts of problematic interactions by teens is described. For example, a social networking system may receive, from a first account of the social networking system, an indication of an interaction between the first account and a content item. Based on determining that the interaction is a problematic interaction, the social networking system may send, to a second account associated with the first account, a notification of the problematic interaction. The social networking system may cause presentation, to the second account, of a selectable control associated with one or more resources regarding addressing the problematic interaction.

Abstract: Described embodiments provide systems, methods, non-transitory computer-readable medium for using a single sign-on (SSO) to access an application. A client application on a client device in communication with an identity provider and an application on a remote computing device. The client application can authenticate a user via an identity provider to establish an authentication session. The client application can identify a request to access a uniform resource locator (URL) of the application hosted on the remote computing device. The client application can determine that a configuration of the client application identifies a remapped URL for the URL is available. The client application can access the remapped URL instead of the URL to cause the user to use the authentication session of the identity provider and be redirected from the identity provider to a link of the application on the remote computing device.

Abstract: The present disclosure relates to, among other things, compounds and methods for treating neuropathic pain, ocular pain, ocular inflammation, and/or dry eye and methods of detecting mutations in specific G-protein coupled receptors, such as missense mutations, and determining the extent to which these mutations alter the pharmacological response of the G-protein coupled receptor.

Abstract: A hybrid drivetrain is provided. The hybrid drivetrain comprises a power source, a transmission, and a tandem axle assembly. The transmission includes a primary clutch and is drivingly engaged with the power source. The tandem axle assembly includes a first axle and a second axle and is drivingly engaged with the transmission. One of the transmission and the tandem axle assembly includes a first motor generator in electrical communication with a battery. The first motor generator and the primary clutch facilitate operating the hybrid drivetrain as a hybrid drivetrain in a plurality of operating modes. The hybrid drivetrain may further comprise second and third motor generators in electrical communication with the battery to facilitate operating the hybrid drivetrain in a plurality of operating modes.

Abstract: The present disclosure relates to compositions, methods of making, and methods of using a modified silk-based composition having a selectively tunable hydrophobicity. The provided compositions include silk fibroin having a haloalkyl substituent. The haloalkyl substituent is coupled to an amino acid of the silk fibroin though a linking agent.

Abstract: Described is a method in a cloud-based system for implementing changes to flow engine software that executes user-specific flows for a plurality of users. The method includes: receiving a request to load and execute a user-specific flow; identifying an API version identifier for the user-specific flow; loading the user-specific flow; determining whether a software change to the flow engine software should be applied when executing the user-specific flow based on the API version identifier; and executing the user-specific flow using the flow engine software with the software change when it is determined, based on the API version identifier, that the software change to the flow engine software should be applied.

Abstract: A system and method for dynamically shaping an inter-datacenter traffic. The method encompasses receiving, one or more inter-datacenter data packets of the inter-datacenter traffic, wherein each inter-datacenter data packet is associated with a corresponding application and/or application interaction. The method thereafter encompasses identifying, one or more target application flow policies for said each inter-datacenter data packet from one or more application flow policies pre-stored in one or more eBPF maps. The method thereafter leads to dynamically marking, a priority for said each inter-datacenter data packet using an eBPF XDP techstack, based at least on the identified one or more target application flow policies. Further the method encompasses transmitting to an edge router, said each inter-datacenter data packet with the corresponding marked priority.

Abstract: Method and system relating to firewall configuration have been discussed. According to an embodiment, a method comprises specifying at least one firewall configuration at a first server at which the at least one firewall configuration is to be enforced; to a plurality of servers, distributing the at least one specified firewall configuration along with a set of parameters to identify the plurality of servers at which the at least one specified firewall configuration has to be enforced; receiving a data packet by a second server of the plurality of servers from the first server; and comparing the at least one specified firewall configuration with a default set of firewall configuration while receiving the data packet by the second server of the plurality of servers from the first server.

Abstract: Described embodiments provide systems, methods, non-transitory computer-readable medium for using a single sign-on (SSO) to access an application. A client application on a client device in communication with an identity provider and an application on a remote computing device. The client application can authenticate a user via an identity provider to establish an authentication session. The client application can identify a request to access a uniform resource locator (URL) of the application hosted on the remote computing device. The client application can determine that a configuration of the client application identifies a remapped URL for the URL is available. The client application can access the remapped URL instead of the URL to cause the user to use the authentication session of the identity provider and be redirected from the identity provider to a link of the application on the remote computing device.

Abstract: Described embodiments provide systems and methods for accessing a web application hosted in an intranet from outside said intranet. A server hosting a domain name service configured for the intranet can receive a request from a client that is outside the intranet to access the web application. The request may include a fully qualified domain name (FQDN) of the web application in the intranet. Responsive to the FQDN of the web application in the intranet, the server may send a notification to an access service, to cause the access service to pre-establish a connection to the intranet. Responsive to the FQDN of the web application in the intranet, the server may direct the client to send a handshake message to the access service to request access to the web application.

Abstract: A system [100] and method [200] for migration of virtual machine(s). The method [200] encompasses identifying, the virtual machine(s) hosted under a first server unit configured in a network to migrate to a second server unit. The method [200] thereafter comprises broadcasting in the network, a GARP response generated by one of the virtual machine(s) and the first server unit. Further the method [200] comprises enabling, an IP forwarding on the second server unit. The method [200] thereafter encompasses enabling, a Proxy ARP on a first network node associated with the first server unit and a second network node associated with the second server unit. Further the method [200] comprises migrating, the virtual machine(s) to the second server unit from the first server unit based at least on the GARP, the enabled IP forwarding and the enabled Proxy ARP.