Patents by Inventor Kristian Solem
Kristian Solem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200397582Abstract: An implantable medical device for transcatheter delivery is disclosed including: an anchor unit configured to be permanently anchored at a cardiac valve of a patient. At least one locking unit is provided for fixation of tissue of the cardiac valve and/or fixation of at least a part of a shape of the anchor unit and/or for connection to a further unit via the at least one coupling unit. The further unit is preferably a cardiac valve replacement or repair unit and/or a driving unit such as of a cardiac assist device. The device further includes at least one coupling unit of fixed permanent length or non-reversibly adjustable length before locking the coupling unit to the fixed permanent length for connecting the anchor unit to at least one of the locking unit. The coupling unit has a first end portion and a second end portion. The first end portion is connectable to the anchor unit, and the second end portion includes the locking unit.Type: ApplicationFiled: August 31, 2020Publication date: December 24, 2020Inventors: Kristian Solem, Jan Otto Solem, Daniel Engvall, Victoria Krüger, Martin Wolff, Jonathan Berg, André Spånberg
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Publication number: 20200390552Abstract: An implantable medical device for transcatheter delivery is disclosed including: an anchor unit configured to be permanently anchored at a cardiac valve of a patient. At least one locking unit is provided for fixation of tissue of the cardiac valve and/or fixation of at least a part of a shape of the anchor unit and/or for connection to a further unit via the at least one coupling unit. The further unit is preferably a cardiac valve replacement or repair unit and/or a driving unit such as of a cardiac assist device. The device further includes at least one coupling unit of fixed permanent length or non-reversibly adjustable length before locking the coupling unit to the fixed permanent length for connecting the anchor unit to at least one of the locking unit. The coupling unit has a first end portion and a second end portion. The first end portion is connectable to the anchor unit, and the second end portion includes the locking unit.Type: ApplicationFiled: August 31, 2020Publication date: December 17, 2020Inventors: Kristian Solem, Jan Otto Solem, Daniel Engvall, Victoria Krüger, Martin Wolff, Jonathan Berg, André Spånberg
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Patent number: 10792153Abstract: An implantable medical device is disclosed including an anchor unit configured to be permanently anchored at a cardiac valve of a patient, at least one locking unit, such as for fixation of tissue of the cardiac valve and/or fixation of at least a part of a shape of the anchor unit, and at least one coupling unit for connecting the anchor unit to at least one of the locking unit. The coupling unit has a first end portion and a second end portion, wherein the first end portion is connectable to the anchor unit, and the second end portion includes the locking unit.Type: GrantFiled: July 10, 2018Date of Patent: October 6, 2020Assignee: Syntach AGInventors: Kristian Solem, Jan Otto Solem, Daniel Engvall, Victoria Krüger, Martin Wolff, Jonathan Berg, André Spånberg
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Patent number: 10729835Abstract: A monitoring device operates on a pressure signal from a blood processing apparatus which has an extracorporeal blood circuit for pumping blood through a dialyzer, and a treatment fluid supply system for pumping a treatment fluid through the dialyzer. The monitoring device has a first input block for obtaining a first pressure signal, and a second input block for obtaining a second pressure signal. An emulation block generates, as a function of the second pressure signal, an emulated first pressure signal which emulates a concurrent signal response of the first pressure sensor, and a filtering block generates a filtered signal as a function of the first pressure signal and the emulated first pressure signal, so as to suppress, in the filtered signal compared to the first pressure signal, signal interferences originating from the treatment fluid supply system. A pulse detection block processes the filtered signal for detection of subject pulses.Type: GrantFiled: October 15, 2018Date of Patent: August 4, 2020Assignee: GAMBRO LUNDIA ABInventors: Jan Sternby, Mattias Holmer, Bo Olde, Kristian Solem, Anders Wallenborg, Per Hansson
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Publication number: 20200237990Abstract: An extracorporeal blood treatment apparatus includes a filtration unit (2) connected to a blood circuit (17) and a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e. spent dialysis fluid); a control unit (12) configured for setting a sodium concentration in the dialysis fluid and after setting the dialysis fluid at the initial set point, circulating the dialysis fluid and blood through the filtration unit (2), measuring an initial conductivity value of the dialysate at the beginning of the treatment, and calculating, based on the measured initial conductivity value and on the corresponding conductivity value of the dialysis fluid, the value of the initial plasma conductivity, said circulating of the dialysis fluid up to the calculating of the initial plasma conductivity performed by maintaining the dialysis fluid conductivity substantially constant.Type: ApplicationFiled: April 15, 2020Publication date: July 30, 2020Inventors: Paolo ROVATTI, Alessandro SURACE, Carlo Alberto LODI, Anders WALLENBORG, Anders NILSSON, Kristian SOLEM, Jan STERNBY, Thomas HERTZ
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Patent number: 10646632Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.Type: GrantFiled: May 23, 2016Date of Patent: May 12, 2020Assignee: GAMBRO LUNDIA ABInventors: Paolo Rovatti, Alessandro Surace, Carlo Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz
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Patent number: 10569005Abstract: A monitoring device detects a disruption of a fluid connection between first and second fluid containing systems using one or more pressure sensors arranged in the first fluid containing system to detect first pulses from the first fluid containing system and second pulses from the second fluid containing system. The monitoring device receives (501) pressure signal(s) from the pressure sensor(s), populates (504) signal vectors by signal segments in the pressure signal(s) and computes (505) one or more eigenvectors and/or one or more eigenvalues for the signal vectors by a source separation algorithm. The monitoring device detects (506) the disruption based on a monitoring parameter, which is computed as a function of the eigenvector(s) and/or eigenvalue(s) to be responsive to the second pulses in the pressure signal(s). The monitoring device may be associated with or included in an apparatus for extracorporeal blood processing, such as a dialysis machine.Type: GrantFiled: June 3, 2016Date of Patent: February 25, 2020Assignee: Gambro Lundia ABInventors: Kristian Solem, Bo Olde
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Publication number: 20200015969Abstract: An implantable medical device is disclosed including an anchor unit configured to be permanently anchored at a cardiac valve of a patient, at least one locking unit, such as for fixation of tissue of the cardiac valve and/or fixation of at least a part of a shape of the anchor unit, and at least one coupling unit for connecting the anchor unit to at least one of the locking unit. The coupling unit has a first end portion and a second end portion, wherein the first end portion is connectable to the anchor unit, and the second end portion includes the locking unit.Type: ApplicationFiled: July 10, 2018Publication date: January 16, 2020Inventors: Kristian Solem, Jan Otto Solem, Daniel Engvall, Victoria Krüger, Martin Wolff, Jonathan Karlsson, André Spånberg
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Publication number: 20200015970Abstract: An at least partial annuloplasty ring for transcatheter cardiac valve treatment is disclosed. The annuloplasty ring has a plurality of separate chain segments serially interlinked and articulated to a chain. The chain has a substantially elongate delivery configuration and a curved deployment configuration. At least one of said chain segments has at least one tissue anchor attached to it, wherein the tissue anchor is movably arranged at least partly within the chain segment in the delivery configuration and protrudes from the chain segment in the deployment configuration in order to anchor with cardiac tissue.Type: ApplicationFiled: July 10, 2018Publication date: January 16, 2020Inventors: Jan Otto Solem, Kristian Solem, Daniel Engvall, Victoria Krüger, Martin Wolff, Jonathan Berg, André Spånberg
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Patent number: 10507279Abstract: A control system (23) is arranged to control the operation of an apparatus (200) for extracorporeal blood treatment. The apparatus (200) comprises an extracorporeal blood circuit (20) and a connection system (C) for connecting the blood circuit (20) to the vascular system of a patient. The blood circuit (20) comprises a blood processing device (6), and at least one pumping device (3). The control system is operable to switch between a pre-treatment mode and a blood treatment mode. The blood treatment mode involves operating the blood circuit (20) to pump blood from the vascular system via the connection system (C) through the blood processing device (6) and back to the vascular system via the connection system (C). The control system (23) is operable to obtain measurement data from at least one energy transfer sensor (40) arranged to sense a transfer of energy between the patient and the connection system (C) or between the patient and the blood circuit (20).Type: GrantFiled: October 31, 2017Date of Patent: December 17, 2019Assignee: Gambro Lundia ABInventors: Bo Olde, Kristian Solem, Thomas Hertz, Jan Sternby, Anders Wieslander
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Publication number: 20190374697Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.Type: ApplicationFiled: October 27, 2017Publication date: December 12, 2019Inventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
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Patent number: 10478076Abstract: A device is configured to monitor a cardiovascular property of a subject. The device obtains measurement data from a primary pressure wave sensor arranged to detect pressure waves in an extracorporeal fluid circuit in fluid communication with the cardiovascular system of the subject. The device has a signal processor configured to generate a time-dependent monitoring signal based on the measurement data, such that the monitoring signal comprises a sequence of heart pulses, wherein each heart pulse represents a pressure wave originating from a heart beat in the subject; determine beat classification data for each heart pulse in the monitoring signal; and calculate, based at least partly on the beat classification data, a parameter value indicative of the cardiovascular property. The beat classification data may distinguish between heart pulses originating from normal heart beats and heart pulses originating from ectopic heart beats.Type: GrantFiled: December 22, 2010Date of Patent: November 19, 2019Assignee: Gambro Lundia ABInventors: Bo Olde, Kristian Solem
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Patent number: 10434236Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.Type: GrantFiled: May 23, 2016Date of Patent: October 8, 2019Assignee: Gambro Lundia ABInventors: Paolo Rovatti, Alessandro Surace, Carlo Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz
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Publication number: 20190275230Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.Type: ApplicationFiled: October 26, 2017Publication date: September 12, 2019Inventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
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Patent number: 10391225Abstract: An apparatus (1) is described for extracorporeal blood treatment, comprising a treatment unit (2), an extracorporeal blood circuit (8) and a fluid evacuation line (10). A venous chamber (12) is placed in a blood return line (7) and is arranged in use to contain a gas in an upper portion (120) and blood at a predetermined level in a lower portion. The apparatus (1) comprises a control unit (21) connected to a first pressure sensor (14) and configured to: receive from the first pressure sensor (14) a first signal (P1(t)) relating to a time variable pressure (P(t)) of the blood flow; calculate a phase shift (?) between the first signal (P1(t)) and a reference signal (P2(t)) correlated to the time variable pressure (P(t)) detected at a location distinct from the upper portion (120) of the chamber (12); monitor the volume (V) of gas in the upper portion (120) of the chamber (12) through the phase shift (?).Type: GrantFiled: December 9, 2014Date of Patent: August 27, 2019Assignee: Gambro Lundia ABInventors: Kristian Solem, David Stefani, Sture Hobro, Bo Olde
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Patent number: 10314965Abstract: A filtering device receives a signal from a pressure sensor in an extracorporeal fluid circuit connected to a subject and processes the signal to separate physiological pulses, e.g. from the subject's heart, from interference pulses, e.g. from a pump in the fluid circuit. The device repeatedly (iteratively) processes a signal segment by alternately subtracting (S3) a template signal from the signal segment, and applying a refinement processing (S6) to the resulting difference signal to generate a new template signal. By proper selection (S2) of the initial template signal, consecutive difference signals will alternately approximate the sequence of interference pulses in the signal segment and the sequence of physiological pulses in the signal segment. The refinement processing (S6) aims at alternately cleaning up unwanted residuals from interference pulses and physiological pulses, respectively, in the respective difference signal, so as to improve the accuracy of the template signal between the subtractions.Type: GrantFiled: September 8, 2014Date of Patent: June 11, 2019Assignee: GAMBRO LUNDIA ABInventors: Mattias Holmer, Bo Olde, Kristian Solem, Leif Sornmo
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Publication number: 20190046709Abstract: A monitoring device operates on a pressure signal from a blood processing apparatus which has an extracorporeal blood circuit for pumping blood through a dialyzer, and a treatment fluid supply system for pumping a treatment fluid through the dialyzer. The monitoring device has a first input block for obtaining a first pressure signal, and a second input block for obtaining a second pressure signal. An emulation block generates, as a function of the second pressure signal, an emulated first pressure signal which emulates a concurrent signal response of the first pressure sensor, and a filtering block generates a filtered signal as a function of the first pressure signal and the emulated first pressure signal, so as to suppress, in the filtered signal compared to the first pressure signal, signal interferences originating from the treatment fluid supply system. A pulse detection block processes the filtered signal for detection of subject pulses.Type: ApplicationFiled: October 15, 2018Publication date: February 14, 2019Inventors: Jan Sternby, Mattias Holmer, Bo Olde, Kristian Solem, Anders Wallenborg, Per Hansson
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Patent number: 10137233Abstract: A monitoring device (7) operates on a pressure signal from a blood processing apparatus, e.g. a dialysis machine, which has an extracorporeal blood circuit connected to a vascular system of a subject for pumping blood through a dialyzer, and a treatment fluid supply system for pumping a treatment fluid through the dialyzer. The monitoring device (7) has a first input block (50) for obtaining a first pressure signal (y) from a first pressure sensor (6a) in the extracorporeal blood circuit, and a second input block (51) for obtaining a second pressure signal (w) from a second pressure sensor (6b) in the treatment fluid supply system.Type: GrantFiled: December 11, 2013Date of Patent: November 27, 2018Assignee: GAMBRO LUNDIA ABInventors: Jan Sternby, Mattias Holmer, Bo Olde, Kristian Solem, Anders Wallenborg, Per Hansson
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Publication number: 20180296744Abstract: A monitoring device detects a disruption of a fluid connection between first and second fluid containing systems using one or more pressure sensors arranged in the first fluid containing system to detect first pulses from the first fluid containing system and second pulses from the second fluid containing system. The monitoring device receives (501) pressure signal(s) from the pressure sensor(s), populates (504) signal vectors by signal segments in the pressure signal(s) and computes (505) one or more eigenvectors and/or one or more eigenvalues for the signal vectors by a source separation algorithm. The monitoring device detects (506) the disruption based on a monitoring parameter, which is computed as a function of the eigenvector(s) and/or eigenvalue(s) to be responsive to the second pulses in the pressure signal(s). The monitoring device may be associated with or included in an apparatus for extracorporeal blood processing, such as a dialysis machine.Type: ApplicationFiled: June 3, 2016Publication date: October 18, 2018Inventors: Kristian SOLEM, Bo OLDE
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Publication number: 20180296745Abstract: A signal filtering device acquires one or more pressure signals that comprise first pulses originating from a first pulse generator associated with a fluid containing system and second pulses. The signal filtering device populates (504) signal vectors by signal segments in the pressure signal(s) and computes (505) principal components for the signal vectors by Principal Component Analysis (PCA). A filtered signal is generated by selecting (506) a first subset of principal components mainly representing the first pulses, determining (507) associated weights, and subtracting (508) the principal components in the first subset from the pressure signal as a function of the weights. Alternatively, a filtered signal is generated by selecting (506) a second subset of principal components that are excluded from the first subset, determining (507) associated weights, and combining (508) the principal components in the second subset as a function of the weights.Type: ApplicationFiled: June 3, 2016Publication date: October 18, 2018Inventors: Bo OLDE, Kristian SOLEM