Patents by Inventor Kunlin Cao

Kunlin Cao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11847547
    Abstract: Methods and Systems for generating a centerline for an object in an image and computer readable medium are provided. The method includes receiving an image containing the object. The method also includes generating the centerline of the object, by a processor, using a reinforcement learning network configured to predict movement of a virtual agent that traces the centerline in the image. The reinforcement learning network is further configured to perform at least one auxiliary task that detects a bifurcation in a trajectory of the object. The reinforcement learning network is trained by maximizing a cumulative reward and minimizing an auxiliary loss of the at least one auxiliary task. Additionally, the method includes displaying the centerline of the object.
    Type: Grant
    Filed: March 11, 2022
    Date of Patent: December 19, 2023
    Assignee: SHENZHEN KEYA MEDICAL TECHNOLOGY CORPORATION
    Inventors: Xin Wang, Youbing Yin, Qi Song, Junjie Bai, Yi Lu, Yi Wu, Feng Gao, Kunlin Cao
  • Patent number: 11776149
    Abstract: A computer-implemented method for predicting a blood vessel stenosis is disclosed. The method may include extracting a blood vessel path and its centerline based on the image of the blood vessel. The method may further include determining a candidate stenosis for the blood vessel path and identifying image blocks along the centerline of the blood vessel path within a range of candidate stenosis for the blood vessel path determined based on the candidate stenosis. The method may also include determining a degree of stenosis for the blood vessel path by applying a trained learning network comprising a convolutional neural network and a recurrent neural network on the image blocks within the range of candidate stenosis.
    Type: Grant
    Filed: April 22, 2021
    Date of Patent: October 3, 2023
    Assignee: KEYA MEDICAL TECHNOLOGY CO., LTD.
    Inventors: Xin Wang, Youbing Yin, Junjie Bai, Yuwei Li, Yi Lu, Kunlin Cao, Qi Song
  • Patent number: 11748902
    Abstract: Systems and methods for generating a centerline for an object in an image are provided. An exemplary method includes receiving an image containing the object. The method also includes detecting at least one bifurcation of the object using a trained bifurcation learning network based on the image. The method further includes extracting the centerline of the object based on a constraint condition that the centerline passes through the detected bifurcation.
    Type: Grant
    Filed: May 26, 2021
    Date of Patent: September 5, 2023
    Assignee: SHENZHEN KEYA MEDICAL TECHNOLOGY CORPORATION
    Inventors: Junjie Bai, Zhihui Guo, Youbing Yin, Xin Wang, Yi Lu, Kunlin Cao, Qi Song, Xiaoyang Xu, Bin Ouyang
  • Patent number: 11748879
    Abstract: Embodiments of the disclosure provide systems and methods for detecting a medical condition of a subject. The system includes a communication interface configured to receive a sequence of images acquired from the subject by an image acquisition device and an end-to-end multi-task learning model. The end-to-end multi-task learning model includes an encoder, a Convolutional Recurrent Neural Network (ConvRNN), and at least one of a decoder and a classifier. The system further includes at least one processor configured to extract feature maps from the images using the encoder, capture contextual information between adjacent images in the sequence using the ConvRNN, and detect medical condition of the subject using the classifier based on the extracted feature maps of the image slices and the contextual information or segment each image slice using the decoder to obtain a region of interest indicative of the medical condition based on the extracted feature maps.
    Type: Grant
    Filed: September 21, 2021
    Date of Patent: September 5, 2023
    Assignee: KEYAMED NA, INC.
    Inventors: Feng Gao, Youbing Yin, Danfeng Guo, Pengfei Zhao, Xin Wang, Hao-Yu Yang, Yue Pan, Yi Lu, Junjie Bai, Kunlin Cao, Qi Song, Xiuwen Yu
  • Publication number: 20230177677
    Abstract: The present disclosure relates to a method, a device and a medium for performing vessel segmentation in a medical image. The method may comprise acquiring a medical image for vessel segmentation containing multiple parts, each of which contains vessels with different structural attributes. The method may comprise dividing the medical image into sub-medical images according to the parts by using a processor. The method may comprise determining individual vessel segmentation result for each part by means of using the vessel segmentation model corresponding to the part based on the sub-medical image of the part by using the processor. The method may comprise obtaining a vessel segmentation result of the medical image by means of fusing the individual vessel segmentation results of the sub-medical images of the parts by the processor.
    Type: Application
    Filed: May 11, 2022
    Publication date: June 8, 2023
    Applicant: Shenzhen Keya Medical Technology Corporation
    Inventors: Shaofeng Yuan, Xiaomeng Huang, Tong Zheng, Yuwei Li, Kunlin Cao, Liwei Wang
  • Publication number: 20230037338
    Abstract: The present disclosure is directed to a computer-implemented method and system for anatomical tree structure analysis. The method includes receiving model inputs for a set of positions in an anatomical tree structure. The method further includes applying, by a processor, a learning network to the model inputs. The learning network comprises a set of encoders and a neural network modeling the anatomical tree structure, wherein each encoder provides features extracted from the model input at a corresponding position. The neural network has a plurality of nodes constructed according to the anatomical tree structure and each node is configured to process the extracted features from one or more of the encoders. The method additionally includes providing an output of the learning network as an analysis result of the anatomical tree structure analysis.
    Type: Application
    Filed: October 21, 2022
    Publication date: February 9, 2023
    Applicant: Keya Medical Technology Co., Ltd.
    Inventors: Xin Wang, Youbing Yin, Kunlin Cao, Junjie Bai, Yi Lu, Bin Ouyang, Qi Song
  • Patent number: 11574122
    Abstract: Embodiments of the disclosure provide systems and methods for processing unstructured texts in a medical record. A disclosed system includes at least one processor configured to determine a plurality of word representations of an unstructured text and tag entities in the unstructured text by performing a named entity recognition task on the plurality of word representations. The at least one processor is further configured to determine position embeddings based on positions of words in the unstructured text relative to positions of the tagged entities and concatenate the plurality of word representations with the position embeddings. The at least one processor is also configured to determine relation labels between pairs of tagged entities by performing a relationship extraction task on the concatenated word representations and position embeddings.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: February 7, 2023
    Assignee: SHENZHEN KEYA MEDICAL TECHNOLOGY CORPORATION
    Inventors: Feng Gao, Changsheng Liu, Yue Pan, Youbing Yin, Kunlin Cao, Qi Song
  • Publication number: 20230005113
    Abstract: A method for medical image data enhancement is provided.
    Type: Application
    Filed: May 10, 2022
    Publication date: January 5, 2023
    Applicant: SHENZHEN KEYA MEDICAL TECHNOLOGY CORPORATION
    Inventors: Guang LI, Jinchen LI, Chengwei SUN, Cong CHEN, Kunlin CAO, Qi SONG
  • Publication number: 20220415510
    Abstract: A method and system can be used for disease quantification modeling of an anatomical tree structure. The method may include obtaining a centerline of an anatomical tree structure and generating a graph neural network including a plurality of nodes based on a graph. Each node corresponds to a centerline point and edges are defined by the centerline, with an input of each node being a disease related feature or an image patch for the corresponding centerline point and an output of each node being a disease quantification parameter. The method also includes obtaining labeled data of one or more nodes, the number of which is less than a total number of the nodes in the graph neural network. Further, the method includes training the graph neural network by transferring information between the one or more nodes and other nodes based on the labeled data of the one or more nodes.
    Type: Application
    Filed: August 24, 2022
    Publication date: December 29, 2022
    Applicant: Keya Medical Technology Co., Ltd.
    Inventors: Xin WANG, Youbing Yin, Junjie Bai, Qi Song, Kunlin Cao, Yi Lu, Feng Gao
  • Patent number: 11538161
    Abstract: The disclosure relates to systems and methods for evaluating a blood vessel. The method includes receiving image data of the blood vessel acquired by an image acquisition device, and predicting, by a processor, blood vessel condition parameters of the blood vessel by applying a deep learning model to the acquired image data of the blood vessel. The deep learning model maps a sequence of image patches on the blood vessel to blood vessel condition parameters on the blood vessel, where in the mapping the entire sequence of image patches contribute to the blood vessel condition parameters. The method further includes providing the blood vessel condition parameters of the blood vessel for evaluating the blood vessel.
    Type: Grant
    Filed: September 8, 2020
    Date of Patent: December 27, 2022
    Assignee: SHENZHEN KEYA MEDICAL TECHNOLOGY CORPORATION
    Inventors: Xin Wang, Youbing Yin, Kunlin Cao, Yuwei Li, Junjie Bai, Xiaoyang Xu
  • Patent number: 11508460
    Abstract: The present disclosure is directed to a computer-implemented method and system for anatomical tree structure analysis. The method includes receiving model inputs for a set of positions in an anatomical tree structure. The method further includes applying, by a processor, a set of encoders to the model inputs. Each encoder is configured to extract features from the model input at a corresponding position. The method also includes applying, by the processor, a tree structured network to the extracted features. The tree structured network has a plurality of nodes each connected to one or more of the encoders, and information propagates among the nodes of the tree structured network according to spatial constraints of the anatomical tree structure. The method additionally includes providing an output of the tree structured network as an analysis result of the anatomical tree structure analysis.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: November 22, 2022
    Assignee: KEYA MEDICAL TECHNOLOGY CO., LTD.
    Inventors: Xin Wang, Youbing Yin, Kunlin Cao, Junjie Bai, Yi Lu, Bin Ouyang, Qi Song
  • Publication number: 20220366679
    Abstract: The present disclosure relates to a training method and a training system for training a learning network for medical image analysis. The training method includes: acquiring an original training data set for a learning network with a predetermined structure; performing, by a processor, a pre-training on the learning network using the original training data set to obtain a pre-trained learning network; evaluating, by the processor, the pre-trained learning network to determine whether the pre-trained learning network has an evaluation defect; when the pre-trained learning network has the evaluation defect, performing, by the processor, a data augmentation on the original training data set for the existing evaluation defect; and performing, by the processor, a refined training on the pre-trained learning network using a data augmented training data set.
    Type: Application
    Filed: December 29, 2021
    Publication date: November 17, 2022
    Applicant: Shenzhen Keya Medical Technology Corporation
    Inventors: Junhuan Li, Ruoping LI, Ling Hou, Pengfei Zhao, Yuwei Li, Kunlin Cao, Qi Song
  • Patent number: 11494908
    Abstract: The present disclosure relates to a medical image analysis method, a medical image analysis device, and a computer-readable storage medium. The medical image analysis method includes receiving a medical image acquired by a medical imaging device; determining a navigation trajectory by performing navigation processing on the medical image based on an analysis requirement, the analysis requirement indicating a disease to be analyzed; extracting an image block set along the navigation trajectory; extracting image features using a first learning network based on the image block set; and determining an analysis result using a second learning network based on the image features and the navigation trajectory.
    Type: Grant
    Filed: August 20, 2021
    Date of Patent: November 8, 2022
    Assignee: SHENZHEN KEYA MEDICAL TECHNOLOGY CORPORATION
    Inventors: Ruoping Li, Pengfei Zhao, Junhuan Li, Bin Ouyang, Yuwei Li, Kunlin Cao, Qi Song
  • Patent number: 11462326
    Abstract: A method and system can be used for disease quantification modeling of an anatomical tree structure. The method may include obtaining a centerline of an anatomical tree structure and generating a graph neural network including a plurality of nodes based on a graph. Each node corresponds to a centerline point and edges are defined by the centerline, with an input of each node being a disease related feature or an image patch for the corresponding centerline point and an output of each node being a disease quantification parameter. The method also includes obtaining labeled data of one or more nodes, the number of which is less than a total number of the nodes in the graph neural network. Further, the method includes training the graph neural network by transferring information between the one or more nodes and other nodes based on the labeled data of the one or more nodes.
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: October 4, 2022
    Assignee: KEYA MEDICAL TECHNOLOGY CO., LTD.
    Inventors: Xin Wang, Youbing Yin, Junjie Bai, Qi Song, Kunlin Cao, Yi Lu, Feng Gao
  • Publication number: 20220301154
    Abstract: The present disclosure relates to a medical image analysis method, a medical image analysis device, and a computer-readable storage medium. The medical image analysis method includes receiving a medical image acquired by a medical imaging device; determining a navigation trajectory by performing navigation processing on the medical image based on an analysis requirement, the analysis requirement indicating a disease to be analyzed; extracting an image block set along the navigation trajectory; extracting image features using a first learning network based on the image block set; and determining an analysis result using a second learning network based on the image features and the navigation trajectory.
    Type: Application
    Filed: August 20, 2021
    Publication date: September 22, 2022
    Applicant: SHENZHEN KEYA MEDICAL TECHNOLOGY CORPORATION
    Inventors: Ruoping LI, Pengfei ZHAO, Junhuan LI, Bin OUYANG, Yuwei LI, Kunlin CAO, Qi SONG
  • Patent number: 11416994
    Abstract: Embodiments of the disclosure provide systems and methods for biomedical image analysis. A method may include receiving a plurality of unannotated biomedical images, including a first image and a second image. The method may also include determining that the first image is in a first view and the second image is in a second view. The method may further include assigning the first image to a first processing path for the first orientation. The method may additionally include assigning the second image to a second processing path for the second view. The method may also include processing the first image in the first processing path in parallel with processing the second image in the second processing path. The first path may share processing parameters with the second path. The method may further include providing a diagnostic output based on the processing of the first image and the second image.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: August 16, 2022
    Assignee: KEYAMED NA, INC.
    Inventors: Feng Gao, Hao-Yu Yang, Youbing Yin, Yue Pan, Xin Wang, Junjie Bai, Yi Wu, Kunlin Cao, Qi Song
  • Publication number: 20220222812
    Abstract: The present disclosure provides a method, a device, and a non-transitory computer-readable storage medium for detecting a medical condition of an organ. The method includes obtaining 2D image sequences of the organ in a plurality of different directions and applying a plurality of classification branches to the 2D image sequences. Each classification branch receives a 2D image sequence of one direction and provides a classification result with respect to that direction. Each classification branch includes a convolutional neural network configured to extract first image features from the corresponding 2D image sequence and a recurrent neural network configured to extract second image features from the first image features. The method further includes fusing the classification results provided by the plurality of classification branches for detecting the medical condition.
    Type: Application
    Filed: September 23, 2021
    Publication date: July 14, 2022
    Applicant: Shenzhen Keya Medical Technology Corporation
    Inventors: Jinchen LI, Guang LI, Chengwei SUN, Kunlin CAO, Qi SONG
  • Publication number: 20220198226
    Abstract: Methods and Systems for generating a centerline for an object in an image and computer readable medium are provided. The method includes receiving an image containing the object. The method also includes generating the centerline of the object, by a processor, using a reinforcement learning network configured to predict movement of a virtual agent that traces the centerline in the image. The reinforcement learning network is further configured to perform at least one auxiliary task that detects a bifurcation in a trajectory of the object. The reinforcement learning network is trained by maximizing a cumulative reward and minimizing an auxiliary loss of the at least one auxiliary task. Additionally, the method includes displaying the centerline of the object.
    Type: Application
    Filed: March 11, 2022
    Publication date: June 23, 2022
    Applicant: SHENZHEN KEYA MEDICAL TECHNOLOGY CORPORATION
    Inventors: Xin Wang, Youbing Yin, Qi Song, Junjie Bai, Yi Lu, Yi Wu, Feng Gao, Kunlin Cao
  • Patent number: 11308362
    Abstract: Methods and Systems for generating a centerline for an object in an image and computer readable medium are provided. The method includes receiving an image containing the object. The method also includes generating the centerline of the object by tracing a sequence of patches with a virtual agent. For each patch other than the initial patch, the method determines a current patch based on the position and action of the virtual agent at a previous patch. The method further determines a policy function and a value function based on the current patch using a trained learning network, which includes an encoder followed by a first learning network and a second learning network. The learning network is trained by maximizing a cumulative reward. The method also determines the action of the virtual agent at the current patch. Additionally, the method displays the centerline of the object.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: April 19, 2022
    Assignee: SHENZHEN KEYA MEDICAL TECHNOLOGY CORPORATION
    Inventors: Xin Wang, Youbing Yin, Qi Song, Junjie Bai, Yi Lu, Yi Wu, Feng Gao, Kunlin Cao
  • Publication number: 20220005192
    Abstract: Embodiments of the disclosure provide systems and methods for detecting a medical condition of a subject. The system includes a communication interface configured to receive a sequence of images acquired from the subject by an image acquisition device and an end-to-end multi-task learning model. The end-to-end multi-task learning model includes an encoder, a Convolutional Recurrent Neural Network (ConvRNN), and at least one of a decoder and a classifier. The system further includes at least one processor configured to extract feature maps from the images using the encoder, capture contextual information between adjacent images in the sequence using the ConvRNN, and detect medical condition of the subject using the classifier based on the extracted feature maps of the image slices and the contextual information or segment each image slice using the decoder to obtain a region of interest indicative of the medical condition based on the extracted feature maps.
    Type: Application
    Filed: September 21, 2021
    Publication date: January 6, 2022
    Applicant: KEYAMED NA, INC.
    Inventors: Feng GAO, Youbing Yin, Danfeng Guo, Pengfei Zhao, Xin Wang, Hao-Yu Yang, Yue Pan, Yi Lu, Junjie Bai, Kunlin Cao, Qi Song, Xiuwen Yu