Abstract: The disclosure relates to systems and methods for vessel image analysis. The method includes receiving a set of images along a vessel acquired by a medical imaging device, and determining a sequence of centerline points along the vessel and a sequence of image patches at the respective centerline points based on the set of images. The method further includes detecting plaques based on the sequence of image patches using a first learning network. The first learning network includes an encoder configured to extract feature maps based on the sequence of image patches and a plaque range generator configured to generate a start position and an end position of each plaque based on the extracted feature maps. The method also includes classifying each detected plaque and determining a stenosis degree for the detected plaque, using a second learning network reusing at least part of the parameters of the first learning network and the extracted feature maps.

Abstract: Embodiments of the disclosure provide systems and methods for detecting an intracerebral hemorrhage (ICH). The system includes a communication interface configured to receive a sequence of image slices and an end-to-end multi-task learning model. The sequence of image slices is the head scan images of a subject acquired by an image acquisition device. The end-to-end multi-task learning model includes an encoder, a bi-directional Convolutional Recurrent Neural Network (ConvRNN), a decoder, and a classifier. The system further includes at least one processor configured to extract feature maps from each image slice using the encoder, capture contextual information between adjacent image slices using the bi-directional ConvRNN, and detect the ICH of the subject using the classifier based on the extracted feature maps of the image slices and the contextual information or segment each image slice using the decoder to obtain an ICH region based on the extracted feature maps of the image slice.

Abstract: Systems and methods for generating a centerline for an object in an image are provided. An exemplary method includes receiving an image containing the object. The method also includes detecting at least one bifurcation of the object using a trained bifurcation learning network based on the image. The method further includes extracting the centerline of the object based on a constraint condition that the centerline passes through the detected bifurcation.

Abstract: A computer-implemented method for predicting a blood vessel stenosis is disclosed. The method may include extracting a blood vessel path and its centerline based on the image of the blood vessel. The method may further include determining a candidate stenosis for the blood vessel path and identifying image blocks along the centerline of the blood vessel path within a range of candidate stenosis for the blood vessel path determined based on the candidate stenosis. The method may also include determining a degree of stenosis for the blood vessel path by applying a trained learning network comprising a convolutional neural network and a recurrent neural network on the image blocks within the range of candidate stenosis.

Abstract: Systems and methods for generating a centerline for an object in an image are provided. An exemplary method includes receiving an image containing the object. The method also includes generating a distance cost image using a trained first learning network based on the image. The method further includes detecting end points of the object using a trained second learning network based on the image. Moreover, the method includes extracting the centerline of the object based on the distance cost image and the end points of the object.

Abstract: The present disclosure provides a prediction method for a healthy radius of a blood vessel path, a prediction method for candidate stenosis of a blood vessel path, and a blood vessel stenosis degree prediction device. The prediction method for a healthy radius includes: obtaining a blood vessel radius of the blood vessel path; by a processor, detecting a radius peak of the blood vessel radius of the blood vessel path; and by the processor, predicting the healthy radius of the blood vessel path by performing a regression on the radius peak of the blood vessel radius. The blood vessel stenosis degree prediction device can, in certain embodiments, automatically determine the candidate stenosis and detect the degree of stenosis for the candidate stenosis range, significantly reduce the computation load, improve the detection efficiency and effectively avoid missed detection.

Abstract: The present disclosure relates to a method, storage medium, and system for analyzing an image sequence of a periodic physiological activity. In one implementation, the method includes receiving the image sequence acquired by an imaging device, the image sequence having a plurality of frames, and identifying a feature point in a first frame. The method further includes determining motion vectors for the feature point in the frames of the image sequence. Each motion vector for the feature point is determined based on respective locations of corresponding feature points in frames adjacent to the first frame. The method also includes determining a motion magnitude profile based on the determined motion vectors and determining a phase of each frame in the image sequence based on the motion magnitude profile.

Abstract: The disclosure relates to systems and methods for evaluating a blood vessel. The method includes receiving image data of the blood vessel acquired by an image acquisition device, and predicting, by a processor, blood vessel condition parameters of the blood vessel by applying a deep learning model to the acquired image data of the blood vessel. The deep learning model maps a sequence of image patches on the blood vessel to blood vessel condition parameters on the blood vessel, where in the mapping the entire sequence of image patches contribute to the blood vessel condition parameters. The method further includes providing the blood vessel condition parameters of the blood vessel for evaluating the blood vessel.

Abstract: A method and system can be used for disease quantification modeling of an anatomical tree structure. The method may include obtaining a centerline of an anatomical tree structure and generating a graph neural network including a plurality of nodes based on a graph. Each node corresponds to a centerline point and edges are defined by the centerline, with an input of each node being a disease related feature or an image patch for the corresponding centerline point and an output of each node being a disease quantification parameter. The method also includes obtaining labeled data of one or more nodes, the number of which is less than a total number of the nodes in the graph neural network. Further, the method includes training the graph neural network by transferring information between the one or more nodes and other nodes based on the labeled data of the one or more nodes.

Abstract: Embodiments of the disclosure provide systems and methods for biomedical image analysis. A method may include receiving a plurality of unannotated biomedical images, including a first image and a second image. The method may also include determining that the first image is in a first view and the second image is in a second view. The method may further include assigning the first image to a first processing path for the first orientation. The method may additionally include assigning the second image to a second processing path for the second view. The method may also include processing the first image in the first processing path in parallel with processing the second image in the second processing path. The first path may share processing parameters with the second path. The method may further include providing a diagnostic output based on the processing of the first image and the second image.

Abstract: Embodiments of the disclosure provide systems and methods for detecting an intracerebral hemorrhage (ICH). The system includes a communication interface configured to receive a sequence of image slices and an end-to-end multi-task learning model. The sequence of image slices is the head scan images of a subject acquired by an image acquisition device. The end-to-end multi-task learning model includes an encoder, a bi-directional Convolutional Recurrent Neural Network (ConvRNN), a decoder, and a classifier. The system further includes at least one processor configured to extract feature maps from each image slice using the encoder, capture contextual information between adjacent image slices using the bi-directional ConvRNN, and detect the ICH of the subject using the classifier based on the extracted feature maps of the image slices and the contextual information or segment each image slice using the decoder to obtain an ICH region based on the extracted feature maps of the image slice.

Abstract: The disclosure relates to systems and methods for determining blood vessel conditions. The method includes receiving a sequence of image patches along a blood vessel path acquired by an image acquisition device. The method also includes predicting a sequence of blood vessel condition parameters on the blood vessel path by applying a trained deep learning model to the acquired sequence of image patches on the blood vessel path. The deep learning model includes a data flow neural network, a recursive neural network and a conditional random field model connected in series. The method further includes determining the blood vessel condition based on the sequence of blood vessel condition parameters. The disclosed systems and methods improve the calculation of the sequence of blood vessel condition parameters through an end-to-end training model, including improving the calculation speed, reducing manual intervention for feature extraction, increasing accuracy, and the like.

Abstract: Methods and Systems for generating a centerline for an object in an image and computer readable medium are provided. The method includes receiving an image containing the object. The method also includes generating the centerline of the object by tracing a sequence of patches with a virtual agent. For each patch other than the initial patch, the method determines a current patch based on the position and action of the virtual agent at a previous patch. The method further determines a policy function and a value function based on the current patch using a trained learning network, which includes an encoder followed by a first learning network and a second learning network. The learning network is trained by maximizing a cumulative reward. The method also determines the action of the virtual agent at the current patch. Additionally, the method displays the centerline of the object.

Abstract: Embodiments of the disclosure provide systems and methods for segmenting a medical image. The system includes a communication interface configured to receive the medical image acquired by an image acquisition device. The system also includes a memory configured to store a plurality of learning networks jointly trained using first training images of a first imaging modality and second training images of a second imaging modality. The system further includes a processor, configured to segment the medical image using a segmentation network selected from the plurality of learning networks.

Abstract: The present disclosure provides a prediction method for a healthy radius of a blood vessel path, a prediction method for candidate stenosis of a blood vessel path, and a blood vessel stenosis degree prediction device. The prediction method for a healthy radius includes: obtaining a blood vessel radius of the blood vessel path; by a processor, detecting a radius peak of the blood vessel radius of the blood vessel path; and by the processor, predicting the healthy radius of the blood vessel path by performing a regression on the radius peak of the blood vessel radius. The blood vessel stenosis degree prediction device can, in certain embodiments, automatically determine the candidate stenosis and detect the degree of stenosis for the candidate stenosis range, significantly reduce the computation load, improve the detection efficiency and effectively avoid missed detection.

Abstract: The present disclosure relates to a method, storage medium, and system for analyzing an image sequence of a periodic physiological activity. In one implementation, the method includes receiving the image sequence acquired by an imaging device, the image sequence having a plurality of frames, and identifying a feature point in a first frame. The method further includes determining motion vectors for the feature point in the frames of the image sequence. Each motion vector for the feature point is determined based on respective locations of corresponding feature points in frames adjacent to the first frame. The method also includes determining a motion magnitude profile based on the determined motion vectors and determining a phase of each frame in the image sequence based on the motion magnitude profile.

Abstract: Embodiments of the disclosure provide systems and methods for processing unstructured texts in a medical record. A disclosed system includes at least one processor configured to determine a plurality of word representations of an unstructured text and tag entities in the unstructured text by performing a named entity recognition task on the plurality of word representations. The at least one processor is further configured to determine position embeddings based on positions of words in the unstructured text relative to positions of the tagged entities and concatenate the plurality of word representations with the position embeddings. The at least one processor is also configured to determine relation labels between pairs of tagged entities by performing a relationship extraction task on the concatenated word representations and position embeddings.

Abstract: Systems and methods for generating a centerline for an object in an image are provided. An exemplary method includes receiving an image containing the object. The method also includes generating a distance cost image using a trained first learning network based on the image. The method further includes detecting end points of the object using a trained second learning network based on the image. Moreover, the method includes extracting the centerline of the object based on the distance cost image and the end points of the object.

Abstract: Embodiments of the disclosure provide systems and methods for analyzing a biomedical image including at least one tree structure object. The system includes a communication interface configured to receive a learning model and a plurality of model inputs derived from the biomedical image. The biomedical image is acquired by an image acquisition device. The system further includes at least one processor configured to apply the learning model to the plurality of model inputs to analyze the biomedical image. The learning model includes a first network configured to process the plurality of model inputs to construct respective feature maps and a second network configured to process the feature maps collectively. The second network is a tree structure network that models a spatial constraint of the tree structure object.

Abstract: The present disclosure is directed to a method and device for generating anatomical labels for a physiological tree structure. The method may include receiving a 3D model and a 3D skeleton line of the physiological tree structure. The 3D model is restructured based on medical image data of the physiological tree structure acquired by an imaging device. The method further includes selecting at least one level from extracting geometrical features from a pool of selectable levels. The method also includes extracting, by a processor, geometrical features from the 3D model of the physiological tree structure along the 3D skeleton line at the selected at least one level. The method also includes generating, by the processor, anatomical labels for the physiological tree structure using a trained learning network based on the extracted geometrical features.