Abstract: A cloud computing system is described that communicates with a virtual machine to reattach the face of a patient to brain imaging data before the brain imaging data is transmitted for display on a brain navigation system.

Abstract: Disclosed are techniques for identifying and displaying spatial relationships between a seed parcel and other parcels in a patient's brain. A method can include obtaining connectivity data characterizing, for each pair of parcels including a first parcel and a second parcel from a group of parcels, a connectivity metric measuring a relationship between the first and second parcels in the patient's brain, obtaining brain atlas data, identifying a seed parcel from the group of parcels, determining one or more other parcels in the group of parcels having a connectivity metric with the seed parcel that satisfies a threshold connectivity metric condition to provide at least one seed-connected parcel, and for the seed-connected parcel, providing the brain atlas data and an indication of a degree of the connectivity metric between the seed parcel and seed-connected parcel for display as an overlay on a visualization of the brain atlas data.

Abstract: Porphyrin photosensitizers including 5,15-di(naphthalimide) moieties useful for photocatalytic hydrogen evolution, compositions including the same, and methods of use thereof.

Abstract: Provided herein are porphyrinato-lanthanide complexes useful as theranostic agents and methods of preparation and use thereof. The porphyrinato-lanthanide complexes are useful in the treatment and imaging of cancer.

Abstract: The present invention provides a sabot (8) comprising a first material structure (12, 14) and a second material structure, wherein the first material structure is a lattice and wherein the second material structure is a solid. A munition (100) and a method of manufacturing a sabot are also provided.

Abstract: A cloud computing system is described that communicates with a virtual machine to reattach the face of a patient to brain imaging data before the brain imaging data is transmitted for display on a brain navigation system.

Abstract: The present invention provides a sabot (8) comprising a first material structure (12, 14) and a second material structure, wherein the first material structure is a lattice and wherein the second material structure is a solid. A munition (100) and a method of manufacturing a sabot are also provided.

Abstract: A cloud computing system is described that communicates with a virtual machine to reattach the face of a patient to brain imaging data before the brain imaging data is transmitted for display on a brain navigation system.

Abstract: Provided herein are porphyrinato-lanthanide complexes useful as theranostic agents and methods of preparation and use thereof. The porphyrinato-lanthanide complexes are useful in the treatment and imaging of cancer.

Abstract: The present disclosure relates to porphyrin containing carbon quantum dots useful for bioimaging and/or phytodynamic therapy.

Abstract: The present disclosure relates to porphyrin small molecules that can be represented by, e.g., a compound of Formula IV designed and synthesized for bulk heterojunction (BHJ) organic solar cells (OSCs). Provided are synthesized materials with strong and ordered self-assembly property, leading to form bi-continuous, interpenetrating networks which are required for efficient charge separation and transport in organic solar cells. The power conversion efficiency (PCE) of the solar cells devices based on the embodiments of the present disclosure have the highest PCE among the solution-processed BHJ solar cell based on porphyrin small molecules to date.

Abstract: The present disclosure relates to porphyrin containing carbon quantum dots useful for bioimaging and/or phytodynamic therapy.

Abstract: The present disclosure relates to porphyrin small molecules substitutes designed and synthesized for bulk heterojunction (BHJ) organic solar cells (OSCs). Provided are synthesized materials with strong and ordered self-assembly property, leading to form bi-continuous, interpenetrating networks which are required for efficient charge separation and transport in organic solar cells. The power conversion efficiency (PCE) of the solar cells devices based on the embodiments of the present disclosure have the highest PCE among the solution-processed BHJ solar cell based on porphyrin small molecules up to date.

Abstract: The present invention relates to a new generation of PDT agents based on porphyrin-lanthanide complexes with specific functional groups which can specifically localize on particular tumors, and their PDT processes can be monitored via NIR emission from erbium. In particular, the present invention provides a multi-modal lanthanide-porphyrin PDT agent (Er—R3) that are capable of killing the bladder tumor cells selectivity via 1O2 from porphyrin moiety and affording the fluorescence imaging simultaneously upon Er—R3 binding with the integrin ?v?3 isoform in bladder cancer cells.

Abstract: The present invention relates to a new generation of PDT agents based on porphyrin-lanthanide complexes with specific functional groups which can specifically localize on particular tumors, and their PDT processes can be monitored via NIR emission from erbium. In particular, the present invention provides a multi-modal lanthanide-porphyrin PDT agent (Er—R3) that are capable of killing the bladder tumor cells selectivity via 1O2 from porphyrin moiety and affording the fluorescence imaging simultaneously upon Er—R3 binding with the integrin ?v?3 isoform in bladder cancer cells.

Abstract: The present invention discloses a new modality of photodynamic therapy (PDT) through the design of the present invention's truly dual-functional—PDT and imaging—gadolinium complex (Gd—N) with a molecular formula of: which can target cancer, cells specifically. The present invention provides a PDT drug that can specifically localize on the anionic cell membrane of cancer cells in which its laser-excited photoemission signal can be monitored without triggering the phototoxic generation of reactive oxygen species—singlet oxygen—prior to due excitation. The present invention also provides the use of Gd—N as a tumor selective PDT photosensitizer modality.

Abstract: The present invention discloses a new modality of photodynamic therapy (PDT) through the design of the present invention's truly dual-functional—PDT and imaging—gadolinium complex (Gd-N) with a molecular formula of: which can target cancer, cells specifically. The present invention provides a PDT drug that can specifically localize on the anionic cell membrane of cancer cells in which its laser-excited photoemission signal can be monitored without triggering the phototoxic generation of reactive oxygen species—singlet oxygen—prior to due excitation. The present invention also provides the use of Gd-N as a tumor selective PDT photosensitizer modality.

Abstract: The presently disclosed subject matter relates to methods and compositions for protecting healthy cells from damage due to DNA damaging agents. In particular, the presently disclosed subject matter relates to the protective action of selective cyclin dependent kinase 4/6 (CDK4/6) inhibitors administered to subjects that have been exposed to or that are at risk of exposure to DNA damage.

Abstract: A method for setting boot up configuration in an embedded system includes pulling the DP data pin of a USB interface to the ground by the embedded system, pulling the DM data pin of the USB interface to the ground by the embedded system, and booting up the embedding system into a special mode when at least one of the DP data pin or the DM data pin is externally pulled up above a threshold value.

Abstract: Methods and compounds for production of cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV are provided.