Patents by Inventor Kyle C. Smith

Kyle C. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160244714
    Abstract: Microfluidic devices are described that include a microfluidic channel, a first array of one or more magnets above the microfluidic channel, each magnet in the first array having a magnetic pole orientation opposite to a magnetic pole orientation of an adjacent magnet in the first array, and a second array of one or more magnets beneath the microfluidic channel, each magnet in the second array having a magnetic pole orientation opposite to a magnetic pole orientation of an adjacent magnet in the second array. The first array is aligned with respect to the second array such that magnetic fields emitted by the first array and second array generate a magnetic flux gradient profile extending through the channel. An absolute value of the profile includes a first maximum and a second maximum that bound a local minimum. The local minimum is located within the microfluidic channel or less than 5 mm away from a wall of the microfluidic channel. Methods of using the new devices are also described.
    Type: Application
    Filed: October 20, 2014
    Publication date: August 25, 2016
    Inventors: Philipp S. Spuhler, Kyle C. Smith, Fabio Fachin, Thomas Alan Barber, Ravi Kapur, Mehmet Toner, Vincent Pai, Murat N. Karabacak
  • Publication number: 20160123857
    Abstract: Extracting and concentrating particles from a first fluid sample includes: providing the first fluid sample to a fluid exchange module of a microfluidic device, providing a second fluid sample to the fluid exchange module, in which the first fluid sample and the second fluid sample are provided under conditions such that particle-free portions of the first fluid sample are shifted, and an inertial lift force causes the particles in the first fluid sample to cross streamlines and transfer into the second fluid sample; passing the second fluid sample containing the transferred particles to a particle concentration module under conditions such that particle-free portions of the second fluid sample are shifted, and such that the particles within the second fluid sample are focused to a streamline within the particle concentration module.
    Type: Application
    Filed: November 3, 2015
    Publication date: May 5, 2016
    Inventors: Ravi Kapur, Kyle C. Smith, Mehmet Toner
  • Publication number: 20160121331
    Abstract: A microfluidic device includes a particle sorting region having a first, second and third microfluidic channels, a first array of islands separating the first microfluidic channel from the second microfluidic channel, and a second array of islands separating the first microfluidic channel from the third microfluidic channel, in which the island arrays and the microfluidic channels are arranged so that a first fluid is extracted from the first microfluidic channel into the second microfluidic channel and a second fluid is extracted from the third microfluidic channel into the first microfluidic channel, and so that particles are transferred from the first fluid sample into the second fluid sample within the first microfluidic channel.
    Type: Application
    Filed: November 3, 2015
    Publication date: May 5, 2016
    Inventors: Ravi Kapur, Kyle C. Smith, Mehmet Toner
  • Publication number: 20160123858
    Abstract: A microfluidic device includes: a first microfluidic channel; a second microfluidic channel extending along the first microfluidic channel; and a first array of islands separating the first microfluidic channel from the second microfluidic channel, in which each island is separated from an adjacent island in the array by an opening that fluidly couples the first microfluidic channel to the second microfluidic channel, in which the first microfluidic channel, the second microfluidic channel, and the islands are arranged so that a fluidic resistance of the first microfluidic channel increases relative to a fluidic resistance of the second microfluidic channel along a longitudinal direction of the first microfluidic channel such that, during use of the microfluidic device, a portion of a fluid sample flowing through the first microfluidic channel passes through one or more of the openings between adjacent islands into the second microfluidic channel.
    Type: Application
    Filed: November 3, 2015
    Publication date: May 5, 2016
    Inventors: Ravi Kapur, Kyle C. Smith, Mehmet Toner
  • Patent number: 9278353
    Abstract: This disclosure describes microfluidic devices that include one or more magnets, each magnet being operable to emit a magnetic field; and a magnetizable layer adjacent to the one or more magnets, in which the magnetizable layer is configured to induce a gradient in the magnetic field of at least one of the magnets. For example, the gradient can be at least 103 T/m at a position that is at least 20 ?m away from a surface of the magnetizable layer. The magnetizable layer includes a first high magnetic permeability material and a low magnetic permeability material arranged adjacent to the high magnetic permeability material. The devices also include a microfluidic channel arranged on a surface of the magnetizable layer, wherein a central longitudinal axis of the microfluidic channel is arranged at an angle to or laterally offset from an interface between the high magnetic permeability material and the low magnetic permeability material.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: March 8, 2016
    Assignee: The General Hospital Corporation
    Inventors: Kyle C. Smith, Ramin Haghgooie, Thomas Alan Barber, Ismail Emre Ozkumur, Ravi Kapur, Mehmet Toner
  • Publication number: 20150336096
    Abstract: This disclosure describes microfluidic devices that include one or more magnets, each magnet being operable to emit a magnetic field; and a magnetizable layer adjacent to the one or more magnets, in which the magnetizable layer is configured to induce a gradient in the magnetic field of at least one of the magnets. For example, the gradient can be at least 103 T/m at a position that is at least 20 ?m away from a surface of the magnetizable layer. The magnetizable layer includes a first high magnetic permeability material and a low magnetic permeability material arranged adjacent to the high magnetic permeability material. The devices also include a microfluidic channel arranged on a surface of the magnetizable layer, wherein a central longitudinal axis of the microfluidic channel is arranged at an angle to or laterally offset from an interface between the high magnetic permeability material and the low magnetic permeability material.
    Type: Application
    Filed: June 25, 2013
    Publication date: November 26, 2015
    Inventors: Kyle C. Smith, Ramin Haghgooie, Thomas Alan Barber, Ismail Emre Ozkumur, Ravi Kapur, Mehmet Toner
  • Patent number: 9166228
    Abstract: A method is provided for forming a high-capacity, high-rate lithium ion battery cathode material. The method includes providing a synthesized material of electrochemically active plate-shaped nanoparticles and adding a plurality of appropriately sized diluent particles to the plate-shaped nanoparticles to form a suspension. Any liquid is removed from the solution to form a composite material. The method also includes processing the composite material to form a high-capacity, high-rate lithium ion battery cathode material.
    Type: Grant
    Filed: November 7, 2011
    Date of Patent: October 20, 2015
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Kyle C. Smith, Timothy S. Fisher
  • Publication number: 20150155585
    Abstract: Gravity induced flow cell. The flow cell includes first and second reservoirs having a selected volume containing a flowable redox electrode. A membrane separates charged and discharged material. An energy-extraction region includes electronically conductive porous current collectors through or adjacent to which the flowable redox electrodes flow and to which charge transfer occurs. Structure is provided for altering orientation of the flow cell whereby gravity induces flow of the flowable redox electrode between the first and second reservoirs to deliver power. By varying the angle of the cell, flow rate and power delivered on discharge or the charge rate on charge may be varied.
    Type: Application
    Filed: December 2, 2014
    Publication date: June 4, 2015
    Applicant: Massachusetts Institute of Technology
    Inventors: Brandon James Hopkins, Alexander H. Slocum, Xinwei Chen, Yet-Ming Chiang, Frank Yongzhen Fan, Ahmed Helal, Zheng Li, Kyle C. Smith, W. Craig Carter
  • Patent number: 8739744
    Abstract: A compound shutter system includes a first shutter assembly having at least one louver operable to selectively open and close the first shutter assembly. The compound shutter system also includes a second shutter assembly disposed remotely from the first shutter assembly. The second shutter assembly includes at least one louver operable to selectively open and close the second shutter assembly. The compound shutter system additionally includes a drive element. The drive element operatively connects the first shutter assembly and the second shutter assembly and automatically coordinates operation of the first and second shutter assemblies. A vehicle employing the compound shutter system is also disclosed.
    Type: Grant
    Filed: September 9, 2010
    Date of Patent: June 3, 2014
    Assignee: GM Global Technology Operations LLC
    Inventors: Scott P. Charnesky, Kyle C. Smith, Jeffrey L. Konchan
  • Patent number: 8485296
    Abstract: A louver for a vehicle includes a panel having a central portion and a first outer edge portion. A hinge interconnects the central portion and the first outer edge portion. The louver rotates about a rotation axis in a first direction from an open position to a closed position. The hinge bends to allow the first outer edge portion to move relative to the central portion to reduce an effective moment arm resisting rotational movement of the louver when the louver is bound.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: July 16, 2013
    Assignee: GM Global Technology Operations LLC
    Inventors: Scott P. Charnesky, Kerry A. Charnesky, Michael J. Sigelko, Bradley K. Rogers, Kyle C. Smith
  • Publication number: 20120112132
    Abstract: A method is provided for forming a high-capacity, high-rate lithium ion battery cathode material. The method includes providing a synthesized material of electrochemically active plate-shaped nanoparticles and adding a plurality of appropriately sized diluent particles to the plate-shaped nanoparticles to form a suspension. Any liquid is removed from the solution to form a composite material. The method also includes processing the composite material to form a high-capacity, high-rate lithium ion battery cathode material.
    Type: Application
    Filed: November 7, 2011
    Publication date: May 10, 2012
    Inventors: Kyle C. Smith, Timothy S. Fisher
  • Publication number: 20120067655
    Abstract: A louver for a vehicle includes a panel having a central portion and a first outer edge portion. A hinge interconnects the central portion and the first outer edge portion. The louver rotates about a rotation axis in a first direction from an open position to a closed position. The hinge bends to allow the first outer edge portion to move relative to the central portion to reduce an effective moment arm resisting rotational movement of the louver when the louver is bound.
    Type: Application
    Filed: September 17, 2010
    Publication date: March 22, 2012
    Applicant: GM GLOBAL TECHNOLOGY OPERATIONS, INC.
    Inventors: Scott P. Charnesky, Kerry A. Charnesky, Michael J. Sigelko, Bradley K. Rogers, Kyle C. Smith
  • Publication number: 20120060776
    Abstract: A compound shutter system includes a first shutter assembly having at least one louver operable to selectively open and close the first shutter assembly. The compound shutter system also includes a second shutter assembly disposed remotely from the first shutter assembly. The second shutter assembly includes at least one louver operable to selectively open and close the second shutter assembly. The compound shutter system additionally includes a drive element. The drive element operatively connects the first shutter assembly and the second shutter assembly and automatically coordinates operation of the first and second shutter assemblies. A vehicle employing the compound shutter system is also disclosed.
    Type: Application
    Filed: September 9, 2010
    Publication date: March 15, 2012
    Applicant: GM GLOBAL TECHNOLOGY OPERATIONS, INC.
    Inventors: Scott P. Charnesky, Kyle C. Smith, Jeffrey L. Konchan
  • Publication number: 20090198231
    Abstract: Provided are methods for selecting parameters of an electrical pulse for electroporation to induce apoptosis in a tissue in need of therapeutic removal in a patient. Also provided are methods and apparatuses for treating a disease by inducing apoptosis in a tissue in need of therapeutic removal in a patient. Further provided are computer-readable media having instructions for selecting parameters of an electrical pulse for electroporation to induce apoptosis in a tissue in need of therapeutic removal in a patient.
    Type: Application
    Filed: December 6, 2008
    Publication date: August 6, 2009
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Axel T. Esser, Thiruvallur R. Gowrishankar, Kyle C. Smith, Stephen K. Burns, James C. Weaver
  • Patent number: 4853480
    Abstract: A process for the vapor phase iodination of an aromatic compound which involves combusting an alkyl aromatic iodide in the presence of oxygen to produce molecular iodine and feeding the molecular iodine and an aromatic compound to an oxyiodination reaction to iodinate aromatic compounds.
    Type: Grant
    Filed: August 6, 1987
    Date of Patent: August 1, 1989
    Assignee: Eastman Kodak Company
    Inventors: Gerald C. Tustin, Kyle C. Smith, Mark Rule