Abstract: The present invention relates to a heteroaryl derivative compound and a use thereof. Since the heteroaryl derivative of the present invention exhibits excellent inhibitory activity against EGFR, the heteroaryl derivative can be usefully used as a therapeutic agent for EGFR-associated diseases.

Abstract: In one example, an electronic device includes a semiconductor sensor device having a cavity extending partially inward from one surface to provide a diaphragm adjacent an opposite surface. A barrier is disposed adjacent to the one surface and extends across the cavity, the barrier has membrane with a barrier body and first barrier strands bounded by the barrier body to define first through-holes. The electronic device further comprises one or more of a protrusion pattern disposed adjacent to the barrier structure, which can include a plurality of protrusion portions separated by a plurality of recess portions; one or more conformal membrane layers disposed over the first barrier strands; or second barrier strands disposed on and at least partially overlapping the first barrier strands. The second barrier strands define second through-holes laterally offset from the first through-holes. Other examples and related methods are also disclosed herein.

Abstract: Provided is an anti-mesothelin chimeric antigen receptor that specifically binds to mesothelin. The anti-mesothelin chimeric antigen receptor according to an aspect exhibits a specific binding ability for mesothelin, and thus, may be useful for preventing or treating cancer in which mesothelin is overexpressed.

Abstract: Provided is an anti-mesothelin chimeric antigen receptor that specifically binds to mesothelin. The anti-mesothelin chimeric antigen receptor according to an aspect exhibits a specific binding ability for mesothelin, and thus, may be useful for preventing or treating cancer in which mesothelin is overexpressed.

Abstract: Provided is a refrigerator which allows a pivoting bar to pivot to seal a gap between a pair of doors regardless of whether the door at which the pivoting bar is not installed between the pair of doors is open or closed. The refrigerator includes a guide device which induces the pivoting bar to pivot. Here, the guide device includes a rack that is moved forward and backward linearly depending on opening and closing of the second door and includes a second magnet built therein, a pinion gear engaged with the rack and pivoting when the rack is moved linearly, and a guide unit which includes a guide groove guiding a guide protrusion and is engaged with the pinion gear to move linearly in a direction opposite to that of the rack to allow the pivoting bar to pivot when the pinion gear pivots.

Abstract: A method for manufacturing a battery. According to the method, a combination of binder resin composition and organic solvent causing low dissolution of polymer may be selected before manufacturing a battery. The binder resin composition, organic solvent or both may be applied to the manufacture of a battery to prevent degradation of adhesion of battery devices, and an increase in resistance caused by an increase in viscosity of an electrolyte.

Abstract: The present disclosure provides an energy-saving technology using switching of current of an electrode terminal, which is applied to a capacitive deionization (CDI) water purification apparatus, and control of switching of the current. The water purification apparatus includes a case 110 having an inlet 113 formed in one side thereof and an outlet 115 formed in the opposite side thereof, a plurality of electrode plates 120 accommodated in the case and stacked on one another, and an electrode terminal 130 selectively and electrically connected to the plurality of electrode plates and configured to allow direct current to flow therethrough.

Abstract: Provided is a refrigerator which allows a pivoting bar to pivot to seal a gap between a pair of doors regardless of whether the door at which the pivoting bar is not installed between the pair of doors is open or closed. The refrigerator includes a guide device which induces the pivoting bar to pivot. Here, the guide device includes a rack that is moved forward and backward linearly depending on opening and closing of the second door and includes a second magnet built therein, a pinion gear engaged with the rack and pivoting when the rack is moved linearly, and a guide unit which includes a guide groove guiding a guide protrusion and is engaged with the pinion gear to move linearly in a direction opposite to that of the rack to allow the pivoting bar to pivot when the pinion gear pivots.

Abstract: Provided is an anti-mesothelin chimeric antigen receptor specifically binding to mesothelin. The anti-mesothelin chimeric antigen receptor according to an aspect exhibits an ability to specifically bind to mesothelin, and thus may be usefully applied to preventing or treating mesothelin-overexpressing cancers.

Abstract: A conductive material pre-dispersed slurry for a secondary battery electrode includes: a conductive material; a dispersant for dispersing the conductive material; and a solvent mixed with the conductive material and the dispersant. The dispersant includes a cellulose-based compound and a vinyl-based or acrylic compound, and the cellulose-based compound and the vinyl-based or acrylic compound in the dispersant have a weight ratio of about 25:1 to 1:25.

Abstract: Disclosed are a deionization electrode having ion adsorption layers and ion selective membranes formed at opposite ends thereof, an electrode module configured such that deionization electrodes are stacked, and a deionization unit having electrode modules received therein to separate ions from water. The deionization electrode includes a current collector configured to have a circular flat structure, the current collector having a first hole formed therein, a first porous adsorption layer located on one surface of the current collector, the first adsorption layer being configured to have a flat structure, a second porous adsorption layer located on the other surface of the current collector, the second adsorption layer being configured to have a flat structure, a first ion selective membrane located on the surface of the first adsorption layer, and a second ion selective membrane located on the surface of the second adsorption layer.

Abstract: A separator for an electrochemical device, where the separator includes a semi-crystalline and/or amorphous polymer, such as polyvinyl acetate and polyethylene-co-vinyl acetate, as a binder polymer of an inorganic coating layer. The surfaces of the inorganic particles are at least partially coated with a coupling agent. Therefore, it is possible to prevent the inorganic particles from being detached from the inorganic coating layer. In addition, phase separation is accelerated under a humidified condition in manufacturing the separator so that the surface of the separator may be provided with an adhesive portion in which a large amount of binder polymer is distributed. As a result, the separator may have improved binding force to an electrode.

Abstract: A separator for a secondary battery having improved force of binding to an electrode, and more particularly a separator for a secondary battery including a porous polymer separator substrate and an inorganic layer on at least one surface of the separator substrate. The inorganic layer includes an inorganic material particles and a binder. The binder is a hollow type binder.

Abstract: A separator for an electrochemical device, including a porous polymer substrate and an inorganic coating layer on at least one surface of the porous polymer substrate. The inorganic coating layer includes inorganic particles and a binder resin. The binder resin includes a PVAc-containing first binder resin and a PVDF-containing second binder resin.

Abstract: A separator including a porous polymer substrate having a first surface and a second surface opposite the first surface; a porous coating layer on at least one surface of the porous polymer substrate; and a conductive coating layer on a surface of the porous coating layer opposite the surface of the porous coating layer facing the first surface of the porous polymer substrate. The porous coating layer includes a plurality of inorganic particles and a first binder polymer totally or partially on the surfaces of the inorganic particles to interconnect and fix the inorganic particles. The conductive coating layer includes single-walled carbon nanotubes (SWCNTs) and a second binder polymer.

Abstract: A separator for a lithium secondary battery and a method for manufacturing the same. The separator for a lithium secondary battery includes: a porous polymer substrate; and a porous coating layer on at least one surface of the porous polymer substrate. The porous coating layer includes inorganic particles, a fluorine-containing binder polymer (A), and an ethylenic copolymer (B) having an ethylene monomer-derived repeating unit (a) and a vinyl acetate monomer-derived repeating unit (b). It is possible to provide a separator having improved adhesion peel strength between the porous coating layer and the porous polymer substrate and improved adhesion Lami strength to an electrode at the same time and a method for manufacturing the same by using an ethylenic copolymer having predetermined characteristics.

Abstract: A method for manufacturing a separator for a lithium secondary battery. Particularly, the method for manufacturing a separator for a lithium secondary battery includes the steps of: preparing a slurry for forming a porous coating layer. The porous coating layer includes inorganic particles dispersed in an asymmetric linear ketone solvent and a binder polymer, including a first binder polymer and a second binder polymer, dissolved therein; and applying the slurry for forming a porous coating layer onto a porous polymer substrate having a plurality of pores, followed by drying. The slurry for forming a porous coating layer may be prepared by dissolving a first binder polymer and a second binder polymer having predetermined properties in an asymmetric ketone solvent, and a separator may be obtained by using the slurry for forming a porous coating layer.

Abstract: The present invention provides a dent-resistant cold-rolled steel sheet having excellent dent-resistance properties. According to one embodiment of the present invention, the dent-resistant cold-rolled steel sheet includes, by weight, carbon (C): 0.005% to 0.03%, manganese (Mn): 1.0% to 2.5%, aluminum (Al): 0.2% to 0.8%, sum of chromium (Cr) and molybdenum (Mo): 0.3% to 1.5%, sum of niobium (Nb) and titanium (Ti): 0.001% to 0.01%, phosphorus (P): greater than 0% to 0.02%, sulfur (S): greater than 0% to 0.01%, and the balance of iron (Fe) and other unavoidable impurities, wherein a yield strength (YP) of 195 MPa or greater, a tensile strength (ST) of 340 MPa or greater, elongation (El) of 33% or greater, and a bake hardening (BH) amount of 40 MPa or greater are satisfied.

Abstract: An apparatus and a method for controlling a vehicle includes a driveshaft that transmits a drive torque generated by a drive motor to a wheel, a sensor that obtains a speed of the vehicle, and a controller that monitors the drive torque to determine a change amount of the drive torque, determines a change in a torsion angle of the driveshaft based on the change amount of the drive torque, and determines whether wheel slip occurs based on an amount of speed change of the drive motor according to the change in the torsion angle of the driveshaft. Accordingly, it is possible to accurately determine wheel slip according to the friction of a road surface, providing safe driving to the driver.

Abstract: Provided is an anti-mesothelin chimeric antigen receptor specifically binding to mesothelin. The anti-mesothelin chimeric antigen receptor according to an aspect exhibits an ability to specifically bind to mesothelin, and thus may be usefully applied to preventing or treating mesothelin-overexpressing cancers.