Abstract: A transition metal dichalcogenide (TMD) transistor includes a substrate, an n-type two-dimensional (2D) TMD layer, a metal source electrode, a metal drain electrode, and a gate dielectric. The substrate has a top portion that is an insulating layer, and the n-type 2D TMD layer is on the insulating layer. The metal source electrode, the metal drain electrode, and the gate dielectric are on the n-type 2D TMD layer. The metal gate electrode is on top of the gate dielectric and is between the metal source electrode and the metal drain electrode.

Abstract: A substrate processing method is provided. The substrate processing method comprises loading a substrate onto a substrate support inside a chamber, forming a plasma inside the chamber, providing a first DC pulse signal to an electromagnet that generates a magnetic field inside the chamber and processing the substrate with the plasma, wherein the first DC pulse signal is repeated at a first period including a first section and a second section subsequent to the first section, the first DC pulse signal has a first level during the first section, and the first DC pulse signal has a second level different from the first level during the second section.

Abstract: A solid state optical beam steering device including a body of electro-optical material wherein the body of electro-optical material comprises any material of a class of hydrogen-doped phase-change metal oxide and wherein the body has a first face and a second face opposite the first face, a first transparent resistive sheet on the first face of the body of electro optic material, wherein the first transparent resistive sheet has a first side and a second side, and a transparent conductor on the second face of the body of electro optic material, wherein the transparent conductor is coupled to the second side of the first transparent resistive sheet.

Abstract: Provided is a method performed by a least one computing device for a message service. The method comprises receiving a transmission request for a compound message which is a bundled message comprising a parent message and a plurality of child messages, obtaining permission information for a sender of the compound message, determining whether to allow each of the child messages to be sent based on the permission information and controlling transmission of the compound message based on the determination result.

Abstract: The present invention provides a pharmaceutical composition for preventing or treating inflammatory diseases, containing, as an active ingredient, stem cells overexpressing SOD3. The present inventor has ascertained that mesenchymal stem cells (MSCs) overexpressing SOD3 have a stronger antioxidant activity and immune regulatory function than normal MSCs, and thus the MSCs overexpressing SOD3 can be an effective treatment agent for inflammatory diseases, autoimmune diseases, organ transplant rejection and the like.

Abstract: A 3-dimensional (3D) printing device using a support body composition including a curing agent includes a support body, a structure body, and a controller, in which the support body composition includes a curing agent configured to cure the structure body.

Abstract: The present invention provides methods for treating or ameliorating metabolic diseases, cholestatic liver diseases, or organ fibrosis, which comprises administering to a subject a therapeutically effective amount of a pharmaceutical composition comprising an isoxazole derivative, a racemate, an enantiomer, or a diastereoisomer thereof, or a pharmaceutically acceptable salt of the derivative, the racemate, the enantiomer, or the diastereoisomer.

Abstract: Adenosine receptor (e.g., A2A and/or A1 receptor) antagonist compounds and compositions including said compounds are disclosed. The present disclosure also provides methods of using said compounds and compositions for modulating (e.g., inhibiting or antagonizing) A2A and/or A1 receptor in a biological system. The compounds and compositions find use in various therapeutic applications including the treatment of central nervous system or neurodegenerative diseases, such as Parkinson's disease. The compounds and compositions may also find use in various therapeutic applications including the treatment of cancer and in immuno-oncology.

Abstract: Proposed are a timber-concrete composite slab with a notched plywood shear connector and a manufacturing method thereof. The timber-concrete composite slab may include a plurality of shear connectors disposed with gaps in a width direction, and a plurality of tension members made of wood and each coupled to lower portions of any one and another adjacent one of the shear connectors between the adjacent shear connectors. The timber-concrete composite slab may also include a plurality of heat insulators each bonded or inserted between upper portions of any one and another adjacent one of the shear connectors, and concrete poured in a predetermined height over the shear connectors.

Abstract: The present invention relates to a composition for preparing a decellularized scaffold, including nano graphene oxide. The present inventors crosslinked nano graphene oxide to a decellularized liver scaffold to strengthen the properties of the scaffold and suppress protease activity of the scaffold, and thus have established an optimum crosslinking condition exhibiting the effects of anti-inflammation and polarization to M2 macrophages. That is, since it is confirmed that nano graphene oxide strengthens the durability of the scaffold so that biodegradation is suppressed and, simultaneously, inflammatory responses that may occur after transplantation are minimized, it is expected that nano graphene oxide can be effectively used in the production and transplantation of clinically applicable artificial organs.

Abstract: Provided is a method for constructing an atopic dermatitis skin organoid from human pluripotent stem cells. It was observed that ALI-skin organoids of the presently claimed subject matter formed skin cells, appendages, neural cells, adipocytes, and the like in similar structures to those in the real skin and exhibited greatly improved follicle growth, compared to skin organoids constructed by existing culture methods. In addition, as a result of treatment with Staphylococcus aureus to construct an atopic dermatitis model, a good simulation was made of the characteristics of atopic dermatitis, such as damaged skin barriers, increased epithelium-derived cytokines and downregulated epidermal stem cell expression, causing Staphylococcus aureus colonies, and the like. Thus, the skin organoid of the presently claimed subject matter is expected to find advantageous applications as a real skin model and an atopic dermatitis model.

Abstract: Adenosine receptor (e.g., A2A and/or A1 receptor) antagonist compounds and compositions including said compounds are disclosed. The present disclosure also provides methods of using said compounds and compositions for modulating (e.g., inhibiting or antagonizing) A2A and/or A1 receptor in a biological system. The compounds and compositions find use in various therapeutic applications including the treatment of central nervous system or neurodegenerative diseases, such as Parkinson's disease. The compounds and compositions may also find use in various therapeutic applications including the treatment of cancer and in immuno-oncology.

Abstract: The present invention relates to an anti-inflammatory composition comprising a graphene nano-structure as an active ingredient. Specifically, the present invention relates to a pharmaceutical composition for preventing or treating an inflammatory disease, and a cosmetic composition or feed composition for preventing or improving an inflammatory disease, which include the anti-inflammatory composition, and a method of treating an inflammatory disease, including administering the composition to a subject in need thereof.

Abstract: The present disclosure provides androgen receptor (AR) and phosphodiesterase 5 (PDE-5) inhibitor compounds of the formula (I): and compositions including said compounds. The compounds can provide dual functionality for inhibiting AR and inhibiting PDE-5. The present disclosure also provides methods of using said compounds and compositions for inhibiting AR and PDE-5 in a biological system or biological sample. Also provided are methods of preparing said compounds and compositions, and synthetic precursors of said compounds.

Abstract: The present invention relates to a method of manufacturing an animal cartilage-derived injectable composition, an injectable composition manufactured by the method, and a use thereof. The injectable composition of the present invention includes a collagen-containing biomaterial in a formulation injectable into joint cavity and may induce cartilage tissue regeneration by repairing tissue via direct injection to a target region without surgical incision. In addition, the injectable composition may be used as a therapeutic agent for arthritis by alleviating osteoarthritis not only because the animal cartilage-derived extracellular matrix contained in the injectable composition protects articular cartilage tissue but also because an environment capable of regenerating damaged articular tissue is created by inducing differentiation of intra-articular stem cells into chondrocytes.

Abstract: Proposed is a moisture control module for an automobile lamp, the moisture control module includes a moisture absorption composition in the accommodating part and seals the moisture absorption composition with a breathable film and a cover, thereby reducing mounting time, space, and cost as compared with a pouch type absorbent. In addition, the moisture absorption performance continues for a long time, and when used in a closed device, which is prone to dew condensation inside according to temperature changes, especially when used in automobile lamps, the internal humidity is kept low, so that dew condensation does not occur inside, and at the same time, has the effect of preventing damage to the packaging material, etc.

Abstract: Provided is a method for producing highly functional artificial organs, including blood vessels capable of carrying perfusate, by using aptamers. The aptamers, according to the presently claimed subject matter, enhance blood vessel adhesion ability, viability, angiogenesis potential, and the like when used as a coating agent of a decellularized scaffold, and thus can more efficiently reconstruct vasculature than existing antibodies. Therefore, a vascularized artificial liver produced using the aptamers exhibits the effects of reducing thrombogenesis in vivo as well as enhancing liver function, and thus is expected to be applied as a method for treating diseases by using artificial organs produced using the aptamers according to the presently claimed subject matter.

Abstract: The present invention provides a pharmaceutical composition for preventing or treating inflammatory diseases, containing, as an active ingredient, stem cells overexpressing SOD3. The present inventor has ascertained that mesenchymal stem cells (MSCs) overexpressing SOD3 have a stronger antioxidant activity and immune regulatory function than normal MSCs, and thus the MSCs overexpressing SOD3 can be an effective treatment agent for inflammatory diseases, autoimmune diseases, organ transplant rejection and the like.

Abstract: A cartridge for a high intensity focused ultrasound (HIFU) device and a piezoelectric linear motor are disclosed. By using the cartridge for a HIFU device according to the present invention, a transducer module is coupled to a piezoelectric linear motor driveable in water and embedded in the cartridge, heat generated when a conventional step motor is driven is fundamentally removed, an additional cooling fan is not needed, ultra-low power consumption and ultra-precise transfer can be realized, and thus an effective procedure can be performed. A skin beauty device may include ultrasound and high frequency units, apply a high frequency to a skin to be treated so as to crack a stratum corneum, and apply ultrasound to the skin to be treated, and thus a medicament drug can easily penetrate the treated skin. In addition, the piezoelectric linear motor in which a piezoelectric actuator and a moving shaft are stably coupled is provided.

Abstract: Proposed is a moisture control module for an automobile lamp, the moisture control module includes a moisture absorption composition in the accommodating part and seals the moisture absorption composition with a breathable film and a cover, thereby reducing mounting time, space, and cost as compared with a pouch type absorbent. In addition, the moisture absorption performance continues for a long time, and when used in a closed device, which is prone to dew condensation inside according to temperature changes, especially when used in automobile lamps, the internal humidity is kept low, so that dew condensation does not occur inside, and at the same time, has the effect of preventing damage to the packaging material, etc.