Patents by Inventor Kyungmoo Ryu

Kyungmoo Ryu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220105353
    Abstract: An implantable lead includes a lead body, electrical conductors, and a lead anchor. The lead body includes an electrode segment configured to be positioned along a pericardial membrane of a heart and including a plurality of electrodes configured to at least one of sense electrical signals from the heart or deliver therapy to the heart. The electrical conductors extend through the lead body between distal and proximal ends of the lead body, and are configured to electrically couple the electrodes to a pulse generator. The lead anchor is configured to be secured to a chest wall. The electrical conductors extend through the lead anchor, and the electrode segment extends from the lead anchor to the pericardial membrane. The electrode segment includes a transition portion that is configured to extend a depth into a mediastinum and a contoured portion to extend alongside and curve about the pericardial membrane.
    Type: Application
    Filed: October 5, 2020
    Publication date: April 7, 2022
    Inventors: Gene A. Bornzin, Zoltan Somogyi, Kyungmoo Ryu
  • Patent number: 11291400
    Abstract: A computer implemented method and system to detect P-waves in cardiac activity is provided. The system includes memory to store specific executable instructions. One or more processors are configured to execute the specific executable instructions for obtaining far field cardiac activity (CA) signals for a series of beats, applying a P-wave template to at least one sub-segment of the CA signals to obtain an alignment indicator and calculating an amplitude dependence (AD) indicator based at least in part on the P-wave template and the at least one sub-segment. The system analyzes the alignment indicator based on a first criteria, compares the AD indicator with a second criteria, designates a candidate P-wave to be an actual P-wave based on the analyzing and comparing and records results of the designating.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: April 5, 2022
    Assignee: Pacesetter, Inc.
    Inventors: Gene A. Bornzin, Chunlan Jiang, Jong Gill, Xiaoyi Min, Kyungmoo Ryu, Gabriel A. Mouchawar
  • Patent number: 11291834
    Abstract: A subcutaneous implantable medical device and method (SIMD) provided. A pulse generator (PG) is configured to be positioned subcutaneously within a lateral region of a chest of a patient. The PG has a housing that includes a PG electrode. The PG has an electronics module. An elongated lead is electrically coupled to the pulse generator. The elongated lead includes a first electrode that is configured to be positioned along a first parasternal region proximate a sternum of the patient and a second electrode that is configured to be positioned at an anterior region of the patient. The first and second electrodes are coupled to be electrically common with one another. The electronics module is configured to provide electrical shocks for antiarrhythmic therapy along at least one shocking vector between the PG electrode and the first and second electrodes.
    Type: Grant
    Filed: August 3, 2020
    Date of Patent: April 5, 2022
    Assignee: Pacesetter, Inc.
    Inventors: Xiaoyi Min, Kyungmoo Ryu, Keith Victorine, Stuart Rosenberg, Gene A. Bornzin
  • Publication number: 20220040484
    Abstract: A system and method for managing atrial-ventricular (AV) delay adjustments are provided and includes electrodes configured to be located proximate to an atrial (A) site and at least one of a left bundle branch (LBB) site or a HIS site. An IMD has a header that includes a right atrial (RA) header port, a right ventricular (RV) header port and a left ventricular (LV) header port. The system includes memory configured to store program instructions and one or more processors that, when configured to execute the program instructions measure an AV interval corresponding to an interval between an atrial paced (Ap) event or an atrial sensed (As) event and a sensed ventricular (Vs) event.
    Type: Application
    Filed: August 10, 2020
    Publication date: February 10, 2022
    Inventors: Wenwen Li, Nima Badie, Luke C. McSpadden, Yun Qiao, Avi Fischer, Kyungmoo Ryu
  • Publication number: 20220008724
    Abstract: A method and device for dynamic device based AV delay adjustment are provided. The method provides electrodes that are configured to be located proximate to an atrial (A) site and a right ventricular (RV) site. The method utilizes one or more processors, in an implantable medical device (IMD), for detecting an atrial paced (Ap) event or atrial sensed (As) event. The method determines a measured AV interval corresponding to an interval between the Ap event or the As event and a ventricular sensed event and calculates a percentage-based (PB) offset based on the measured AV interval. The method automatically dynamically adjusting an AV delay, utilized by the IMD, based on the measured AV interval and the PB offset and manages a pacing therapy, utilized by the IMD, based on the AV delay after the adjusting operation.
    Type: Application
    Filed: September 28, 2021
    Publication date: January 13, 2022
    Inventors: Nima Badie, Jan O. Mangual-Soto, Luke C. McSpadden, Aditya Goil, Kyungmoo Ryu
  • Patent number: 11221373
    Abstract: Methods, devices and program products are provided for determining an early battery depletion condition for a battery powered device. The method determines a charge consumption drawn externally from a battery cell by the device for a select period of time, obtains a measured cell voltage for the battery cell of the medical device, calculates a projected cell voltage based on the charge consumption and usage conditions, and declares an early depletion condition based on a relation between the measured and projected cell voltages.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: January 11, 2022
    Assignee: PACESETTER, INC.
    Inventors: Avi Fischer, Gene A. Bornzin, Thomas F. Strange, Xing Pei, Aditya Goil, Fady Dawoud, Kyungmoo Ryu, Joseph Beauvais, Gabriel Mouchawar, Richard Williamson
  • Publication number: 20210379385
    Abstract: System and methods are provided for determining a stimulation threshold for closed loop spinal cord stimulation (SCS). The system and methods provide a lead coupled to an implantable pulse generator (IPG). The system and methods deliver SCS pulses from the IPG to the lead electrodes in accordance with an SCS therapy and determine an evoked compound action potential (ECAP) amplitude based on an ECAP waveform resulting from the SCS therapy. The system and methods increase the SCS therapy by increasing at least one of an amplitude, a duration, and number of the SCS pulses associated with the SCS therapy. The system and methods also include iteratively repeat the delivering, determining and increasing operations until the ECAP amplitude exhibits a downward trend divergence. The system and methods define a stimulation threshold based on the ECAP amplitude at the trend divergence.
    Type: Application
    Filed: August 24, 2021
    Publication date: December 9, 2021
    Inventors: Wenbo Hou, Fujian Qu, Stuart Rosenberg, Kyungmoo Ryu
  • Publication number: 20210369191
    Abstract: Described herein are methods, devices, and systems that use electrogram (EGM) or electrocardiogram (ECG) data for sleep apnea detection. An apparatus and method detect potential apnea events (an apnea or hypopnea event) using a signal indicative of cardiac electrical activity of a patient's heart, such as an EGM or ECG. Variations in one or more morphological or temporal features of the signal over several cardiac cycles are determined and used to detect a potential apnea event in a measurement period. Checks can then be made for a number of factors which could result in a false detection of an apnea event and if such factors are not present, an apnea event is recorded. Described herein are also methods, devices, and systems for classifying a patient as being asleep or awake, which can be used to selectively enable and disable sleep apnea detection monitoring, as well as in other manners.
    Type: Application
    Filed: April 20, 2021
    Publication date: December 2, 2021
    Applicant: Pacesetter, Inc.
    Inventors: Jong Gill, Prakrit Shrestha, Kyungmoo Ryu
  • Publication number: 20210370078
    Abstract: Described herein are methods for use with an implantable system including at least an atrial leadless pacemaker (aLP). Also described herein are specific implementations of an aLP, as well as implantable systems including an aLP. In certain embodiments, the aLP senses a signal from which cardiac activity associated with a ventricular chamber can be detected by the aLP itself based on feature(s) of the sensed signal. The aLP monitors the sensed signal for an intrinsic or paced ventricular activation within a ventricular event monitor window. In response to the aLP detecting an intrinsic or paced ventricular activation itself from the sensed signal within the ventricular event monitor window, the aLP resets an atrial escape interval timer that is used by the aLP to time delivery of an atrial pacing pulse if an intrinsic atrial activation is not detected within an atrial escape interval.
    Type: Application
    Filed: May 14, 2021
    Publication date: December 2, 2021
    Applicant: Pacesetter, Inc.
    Inventors: Xiaoyi Min, Weiqun Yang, Benjamin T. Persson, Nima Badie, Kyungmoo Ryu, Gabriel Mouchawar
  • Publication number: 20210345935
    Abstract: A system for verifying a candidate pathologic episode of a patient is provided. The system includes an accelerometer configured to be implanted in the patient, the accelerometer configured to obtain accelerometer data along at least one axis. The system also includes a memory configured to store program instructions and one or more processors. When executing the program instructions, the one or more processors are configured to obtain a biological signal and identify a candidate pathologic episode based on the biological signal, analyze the accelerometer data to identify a physical action experienced by the patient, and verify the candidate pathologic episode based on the physical action.
    Type: Application
    Filed: March 5, 2021
    Publication date: November 11, 2021
    Inventors: Jong Gill, Kyungmoo Ryu, Fady Dawoud
  • Publication number: 20210345900
    Abstract: A computer implemented method and system to detect P-waves in cardiac activity is provided. The system includes memory to store specific executable instructions. One or more processors are configured to execute the specific executable instructions for obtaining far field cardiac activity (CA) signals for a series of beats, applying a P-wave template to at least one sub-segment of the CA signals to obtain an alignment indicator and calculating an amplitude dependence (AD) indicator based at least in part on the P-wave template and the at least one sub-segment. The system analyzes the alignment indicator based on a first criteria, compares the AD indicator with a second criteria, designates a candidate P-wave to be an actual P-wave based on the analyzing and comparing and records results of the designating.
    Type: Application
    Filed: May 11, 2020
    Publication date: November 11, 2021
    Inventors: Gene A. Bornzin, Chunlan Jiang, Jong Gill, Xiaoyi Min, Kyungmoo Ryu, Gabriel A. Mouchawar
  • Publication number: 20210330239
    Abstract: Computer implemented methods and systems for monitoring cardiac activity (CA) signals, for a series of beats, over first and second sensing channels having different first and second detection thresholds, respectively. The methods and systems also include analyzing the CA signals over the first and second sensing channels utilizing the first and second detection thresholds, respectively, during an event prediction window to detect a presence of sensed events. The methods and systems also include determining amplitudes of the sensed events detected. The methods and systems also include calculating at least one of an amplitude distribution or amplitude trend for the sensed events detected over the first and second channels and adjusting at least one of the first or second detection thresholds based on the at least one of the amplitude distribution or amplitude trend.
    Type: Application
    Filed: March 4, 2021
    Publication date: October 28, 2021
    Inventors: Hanbiao Wang, Xing Pei, Kyungmoo Ryu
  • Patent number: 11154719
    Abstract: A method and device for dynamic device based AV delay adjustment are provided. The method provides electrodes that are configured to be located proximate to an atrial (A) site and a right ventricular (RV) site. The method utilizes one or more processors, in an implantable medical device (IMD), for detecting an atrial paced (Ap) event or atrial sensed (As) event. The method determines a measured AV interval corresponding to an interval between the Ap event or the As event and a ventricular sensed event and calculates a percentage-based (PB) offset based on the measured AV interval. The method automatically dynamically adjusting an AV delay, utilized by the IMD, based on the measured AV interval and the PB offset and manages a pacing therapy, utilized by the IMD, based on the AV delay after the adjusting operation.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: October 26, 2021
    Assignee: Pacesetter, Inc.
    Inventors: Nima Badie, Jan O. Mangual-Soto, Luke C. McSpadden, Aditya Goil, Kyungmoo Ryu
  • Patent number: 11129993
    Abstract: A computer implemented method and system for detecting arrhythmias in cardiac activity are provided. The method is under control of one or more processors configured with specific executable instructions. The method obtains cardiac activity (CA) signals at the electrodes of an implantable medical device (IMD) in connection multiple cardiac beats and with different IMD orientations relative to gravitational force. The method obtains acceleration signatures at a sensor of the IMD that are indicative of heart sounds generated during the cardiac beats. The method obtains device location information at the IMD, with respect to the gravitational force during the cardiac beats. The method groups the acceleration signatures associated with the first and second set of cardiac beats into the corresponding one of first and second posture bins based on the device location information.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: September 28, 2021
    Assignee: Pacesetter, Inc.
    Inventors: Xiaoyi Min, Kyungmoo Ryu, Thanh Tieu, Gene A. Bornzin, Stuart Rosenberg
  • Patent number: 11045643
    Abstract: Methods and devices include making an incision at a single site of a patient. The single site located at an anterior of a chest or abdomen. The method also includes inserting a tunneling tool through the incision at the single site and preparing a first tunnel to a subcutaneous posterior location. A path of the first tunnel at least one of i) extends over a plurality of Intercostal gaps of the chest or ii) extends along and within one of the intercostal gaps. The method also includes positioning a first lead having an electrode within the first tunnel and preparing a second tunnel to a subcutaneous parasternal location along the chest. The method also includes positioning a second lead having an electrode within the second tunnel and positioning a pulse generator within a subcutaneous pocket and operatively coupling the first and second leads to the pulse generator.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: June 29, 2021
    Assignee: Pacesetter, Inc.
    Inventors: Avi Fischer, Xiaoyi Min, Kyungmoo Ryu, Gene A. Bornzin, Keith Victorine, Stuart Rosenberg, Shubha Asopa
  • Patent number: 10850107
    Abstract: Systems and methods of performing cardio resynchronization therapy (CRT) on a patient heart include the use of a stimulation system having at least one processor, at least one memory, a pulse generator, a stimulating electrode disposed in proximity to a His bundle of the patient heart, and a sensing electrode adapted to sense electrical activity of the left ventricle (LV) of the patient heart. CRT is provided by applying, using the pulse generator and through the stimulating electrode, a His bundle pacing (HBP) impulse having a first impulse energy. The sensing electrode is then used to measure an LV activation time in response to the HBP impulse. At least one setting of the pulse generator is modified based on the LV activation time such that a subsequent HBP impulse may be provided by the pulse generator via the stimulating electrode using a modified impulse energy.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: December 1, 2020
    Assignee: PACESETTER, INC.
    Inventors: Wenwen Li, Gene A. Bornzin, Nima Badie, Stuart Rosenberg, Luke C. McSpadden, Kyungmoo Ryu
  • Publication number: 20200360688
    Abstract: A subcutaneous implantable medical device and method (SIMD) provided. A pulse generator (PG) is configured to be positioned subcutaneously within a lateral region of a chest of a patient. The PG has a housing that includes a PG electrode. The PG has an electronics module. An elongated lead is electrically coupled to the pulse generator. The elongated lead includes a first electrode that is configured to be positioned along a first parasternal region proximate a sternum of the patient and a second electrode that is configured to be positioned at an anterior region of the patient. The first and second electrodes are coupled to be electrically common with one another. The electronics module is configured to provide electrical shocks for antiarrhythmic therapy along at least one shocking vector between the PG electrode and the first and second electrodes.
    Type: Application
    Filed: August 3, 2020
    Publication date: November 19, 2020
    Inventors: Xiaoyi Min, Kyungmoo Ryu, Keith Victorine, Stuart Rosenberg, Gene A. Bornzin
  • Patent number: 10765860
    Abstract: A subcutaneous implantable medical device and method (SIMD) provided. A pulse generator (PG) is configured to be positioned subcutaneously within a lateral region of a chest of a patient. The PG has a housing that includes a PG electrode. The PG has an electronics module. An elongated lead is electrically coupled to the pulse generator. The elongated lead includes a first electrode that is configured to be positioned along a first parasternal region proximate a sternum of the patient and a second electrode that is configured to be positioned at an anterior region of the patient. The first and second electrodes are coupled to be electrically common with one another. The electronics module is configured to provide electrical shocks for antiarrhythmic therapy along at least one shocking vector between the PG electrode and the first and second electrodes.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: September 8, 2020
    Assignee: Pacesetter, Inc.
    Inventors: Xiaoyi Min, Kyungmoo Ryu, Keith Victorine, Stuart Rosenberg, Gene A. Bornzin
  • Patent number: 10758730
    Abstract: Methods, devices and program products are provided for controlling a left univentricular (LUV) pacing therapy using an implantable medical device. Electrodes are configured to be located proximate to an atrial (A) site, left ventricular (LV) site and right ventricular (RV) site of the heart. A conduction different ? is determined based on i) an atrial-ventricular conduction delay (ARRV) between the A site and the RV site, and ii) an atrial-ventricular conduction delay (ARLV) between the A site and the LV site. A correction term ? is based on intrinsic inter-ventricular conduction delay (IVCD) between the LV and RV. An LV atrial-ventricular pacing (AVLV) delay is set based on the conduction difference ?, a pacing latency PL and the correction term ? and manages the LUV pacing therapy based on the AVLV delay, wherein the LUV pacing therapy lacks pacing in the RV.
    Type: Grant
    Filed: August 8, 2017
    Date of Patent: September 1, 2020
    Assignee: Pacesetter, Inc.
    Inventors: Xiaoyi Min, Kyungmoo Ryu, Stuart Rosenberg, David Muller
  • Publication number: 20200254238
    Abstract: Methods for implanting a pulse generator (PG) within a pectoral region of a chest of a patient and devices having the PG. The PG has a housing that includes a PG electrode. Methods also include implanting at least one lead having first and second electrode segments with the first electrode segment positioned along an anterior of the chest of the patient and the second electrode segment positioned along at least one of a posterior of the patient or a side of the patient. The first and second electrode segments are positioned subcutaneously at or below an apex of a heart of the patient, wherein the PG electrode and the first and second electrode segments are configured to provide electrical shocks for antiarrhythmic therapy.
    Type: Application
    Filed: April 27, 2020
    Publication date: August 13, 2020
    Inventors: Xiaoyi Min, Avi Fischer, Kyungmoo Ryu, Gabriel A. Mouchawar