Abstract: A multi-fiber alignment system is provided for actively aligning optical fibers to an optical waveguide base on alignment status between each optical fiber and a corresponding optical device. Each of the optical fibers is held by bonding agent on a thermal pad from which radiation melts the bonding agent during adjustment of the optical fiber, and the optical fiber is fixed in its position by solidifying the bonding agent when being accurately aligned to a corresponding optical device.

Abstract: A system and method for fabricating an array of multiple optical fibers is disclosed. The method comprises providing a substrate having a plurality of guides formed therein each penetrating through the substrate, the substrate having one or more via holes in fluid communication with the plurality of guides. The plurality of optical fibers is disposed with respective guides, each of the optical fibers being placed with a corresponding one of the guides. An adhesive is injected into the one or more via holes, the adhesive fixing the optical fibers in the respective guides of the substrate.

Abstract: A method is provided for attaching one or more optical fibers to a retaining device. The method includes: applying a fluid to a through hole in a retaining device; disposing an optical fiber proximate an end of the through hole; developing a differential pressure in the fluid across the through hole; drawing a portion of the optical fiber into the through hole using a force associated with said differential pressure.

Abstract: The present invention provides a method of fabricating a multi-fiber array in which optical fibers are actively aligned to their target positions. The method includes providing an array member for receiving optical fibers, forming in the array member through-holes, placing the optical fibers in the respective through-holes, applying adhesive into the respective through-holes, adjusting position of each optical fiber so that the optical fibers are aligned in accordance with reference measurements, and curing the adhesive to fix the optical fibers aligned in the respective through-holes.

Abstract: This invention relates to novel (Z,Z), (Z,E) and (E,Z) olefin isomers of substituted benzylidene cycloketones and their pharmaceutically acceptable salts. The compounds of the invention are potent factor Xa inhibitors thereby acting as anticoagulants useful in a number of thrombotic disease states. Pharmaceutical compositions are proposed for the compounds.