Abstract: A system, device and method to facilitate tying a knot are provided. In the context of a device, the device includes a fixture defining an internal passage therethrough. The fixture defines a circumferential groove opening through an interior surface of the fixture and into the internal passage. The groove includes first and second groove portions that cross one another. Opposite ends of the groove are coincident and open through an exterior surface of the fixture. With relation to a system, the system includes a fixture and a lead member supply mechanism configured to alternately feed a lead member through the groove and to withdraw the lead member from the groove once the tie member is connected thereto.

Abstract: The disclosure relates to methods and compositions for treating Type 1 diabetes, such as compositions comprising an effector domain linked to a protein that binds to MAdCAM.

Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A powered fastener driver includes a driver unit, a handle unit, and a handle extension. The handle unit is selectively and removably attachable to the driver unit. The handle extension has a first end and a second end, the handle extension being selectively and removably attachable to the driver unit at the first end, and being selectively and removably attachable to the handle unit at the second end. The powered fastener driver is adjustable between a first configuration in which the handle unit is directly attached to the driver unit, and a second configuration in which the driver unit is attached to the handle extension at the first end, and the handle unit is attached to the handle extension at the second end.

Abstract: Provided is a method, computer program product, and system for automatically assigning robotic devices to users based on need using predictive analytics. A processor may monitor activities performed by one or more users. The processor may determine, based on the monitoring, a set of activities that require assistance from a robotic device when being performed by the one or more users. The processor may match the set of activities to a set of capabilities related to a plurality of robotic devices. The processor may identify, based on the matching, a first robotic device that is capable of assisting the one or more users in performing a first activity of the set of activities. The processor may deploy the first robotic device to assist the one or more users in performing the first activity.

Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.

Abstract: A laundry treating appliance for treating laundry items according to an automatic cycle of operation can include a cabinet defining an interior and having an access opening providing access to the interior. A tub can be located within the interior and can at least partially define a liquid chamber. A drum is rotatably mounted within the liquid chamber and at least partially defines a treating chamber. A clothes mover is located within the treating chamber and rotatable about a vertical axis. The clothes mover can include a base and a barrel.

Abstract: A zero-gravity hoist system including a chain fall, a motor coupled to the chain fall and configured to drive the chain fall in one or more directions, a power supply configured to provide power to the motor, and a controller having one or more electronic processors. The one or more electronic processors are configured to measure a first force of a load in response to receiving an input, store the measured first force in a memory of the controller, measure a second force of the load, determine a difference between the second measured force and the first measured force, and adjust a height of the load based on determining that the second force differs from the first force by a predetermined threshold.

Abstract: A paint brush having an adhesive attachment that includes an engagement of a mass of adhesive within one or more pockets in a lower portion of the handle and an engagement of the mass of adhesive with an internal surface of the ferrule to form a permanent assembly. At least one flow passage fluidly connects with the pocket(s) to facilitate and/or permit flow of the adhesive into the pocket(s) during manufacturing of the paint brush. In addition, the paint brush may include an elongated upper portion having a rigid internal spine that is overlayed and surrounded with a more flexible grip.

Abstract: There are provided herein methods and products resulting therefrom. The methods include attaching a pre-fabricated porous ingrowth structure to a substrate by applying heat, or creating and bonding an in-situ-formed porous ingrowth structure from beads on a substrate by applying heat. In some embodiments, an oxidized metal surface of the substrate is diffusion hardened during the heating process. In some embodiments, a vacuum is applied during the heating process. In some embodiments, pressure is applied during the heating process. Also provided herein are assemblies for compressing the pre-fabricated porous ingrowth structure or the beads onto the substrate during the heating process.

Abstract: Apparatuses and methods related to port arbitration of a memory system are described. A memory system can receive a first number of transactions and a second transaction from a first traffic stream and a third number of transactions and a fourth transaction from a second traffic stream. The memory system can process the first number of transactions at least partially concurrently with the third number of transactions. Responsive to a total quantity of transactions of the first number of transactions and the second transaction being at least a threshold quantity of transactions, the second transaction can be processed by the memory system and, subsequent to processing the second transaction, the fourth transaction can be processed by the memory system.

Abstract: Apparatus for powder-free intra-oral 3D imaging by using a projected texture pattern. A projector projects a random texture pattern of light to teeth to be imaged, and a digital image sensor receives the projected texture pattern from the teeth. The reflected pattern of light reflects and scatters from the teeth. The texture pattern can be a grid having clusters of bright and dark blocks in a pseudo-random arrangement and can provide for powder-free intra-oral 3D imaging by using the pattern to optically simulate powder applied to the teeth. Polarizers can be used in the optical path to transmit the directly reflected light to the image sensor and suppress or discard some of the unwanted scattered light.

Abstract: Compositions and methods for chemical enhanced hydrocarbon recovery that utilize a nonionic surfactant that is a mixture of isomerized C9-11 ethoxylated alcohols.

Abstract: A profiler arranged to be used on a host vehicle. The profiler is capable of (a) receiving data collected by the profiler while traveling over a surface and (b) generating a surface profile using the data collected with no minimum speed requirement. Since there is no minimum speed requirement, the profiler is capable of generating valid, repeatable and reliable road surface profiles in situations not previously possible, such as during a stop, during acceleration of the host vehicle, during deceleration of the host vehicle, or while the host vehicle is traveling at very low speeds below thresholds typically required for prior profilers.

Abstract: A method for adjusting control parameters of a clip applier using a surgical hub is disclosed. The method comprises gathering data during a first surgical procedure, evaluating the gathered data to determine the appropriate operation of a clip applier in a subsequent surgical procedure, gathering data during the operation of the clip applier in the subsequent surgical procedure, determining if the operation of the clip applier needs to be adjusted based on the data gathered during the subsequent surgical procedure, and adjusting the operation of the clip applier based on the data gathered during the subsequent surgical procedure.

Abstract: A wireless hoist system including a first hoist device having a first motor and a first wireless transceiver and a second hoist device having a second motor and a second wireless transceiver. The wireless hoist system includes a controller in wireless communication with the first wireless transceiver and the second wireless. The controller is configured to receive a user input and determine a first operation parameter and a second operation parameter based on the user input. The controller is also configured to provide, wirelessly, a first control signal indicative of the first operation parameter to the first hoist device and provide, wirelessly, a second control signal indicative of the second operation parameter to the second hoist device. The first hoist device operates based on the first control signal and the second hoist device operates based on the second control signal.

Abstract: The present invention relates to methods and systems that use natural language processing (NLP) to read data from a file and analyze the data based on user defined parameters. According to an illustrative embodiment of the present disclosure, a system can process and analyze a data file by finding trending themes across data entries. According to a further illustrative embodiment of the present disclosure, the system can search for reoccurring or repeated words/phrases based on Ngrams (i.e., n-grams). The system can be adapted to search for Ngrams of varying length depending on the information sought and can sort the results by Ngram length.