Abstract: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as melanoma, prostate cancer, breast cancer, bone cancer, renal cell carcinoma, and hematologic cancer.

Abstract: Provided are a three-dimensional reconstruction method, apparatus and system of a dynamic scene, a server and a medium. The method includes: acquiring multiple continuous depth image sequences of the dynamic scene, where the multiple continuous depth image sequences are captured by an array of drones equipped with depth cameras; fusing the multiple continuous depth image sequences to establish a three-dimensional reconstruction model of the dynamic scene; obtaining target observation points of the array of drones through calculation according to the three-dimensional reconstruction model and current poses of the array of drones; and instructing the array of drones to move to the target observation points to capture, and updating the three-dimensional reconstruction model according to multiple continuous depth image sequences captured by the array of drones at the target observation points.

Abstract: A method for refurbishing a wind turbine includes positioning a new tower support mount on an existing foundation of the wind turbine, the existing foundation including an existing foundation pad and an existing tower support mount at least partially embedded in the existing foundation pad. The method further includes inserting a plurality of anchors through the new tower support mount.

Abstract: The present disclosure relates to user plane link establishment methods. One example method includes sending, by a first base station, an obtaining request associated with user equipment to a second base station, receiving, by the first base station, a response message corresponding to the obtaining request, where the response message includes a peer address associated with the user equipment, and establishing, by the first base station and based on the peer address, a user plane link corresponding to the user equipment.

Abstract: A method for refurbishing a wind turbine includes positioning a new tower support mount on an existing foundation of the wind turbine, the existing foundation including an existing foundation pad and an existing tower support mount at least partially embedded in the existing foundation pad. The method further includes inserting a plurality of anchors through the new tower support mount.

Abstract: Described herein are selective inhibitors of FGFR4, pharmaceutical compositions including such compounds, and combinations with other therapeutic agents, such as CDK inhibitors (e.g., CDK4/6 inhibitors), and methods of using such combinations.

Abstract: A big data processing system includes a workload trimming function that separates out from among a set of identified anomalies, those that are clearly outliers, rather than ones residing within clusters of anomalies as mapped within an anomalies distribution space. The outlier anomalies are not subjected to a computationally-intensive anomalies aggregating process and thus, processing resources are conserved.

Abstract: Embodiments of the present invention disclose a push information pre-selecting method and apparatus. The method includes: based on historical push data of push information including a plurality of push information items, determining a feature for calculating a predicted value, and a weight corresponding to the feature; calculating a standard deviation of the feature; determining a fluctuation probability of the standard deviation; calculating the predicted value based on the weight, the standard deviation, and the fluctuation probability, the standard deviation and the fluctuation probability being used for calculating a fluctuation value for correcting the weight; based on the predicted value, selecting push information items satisfying a preset condition; and pushing the selected push information items to a target user.

Abstract: A big data processing system includes a workload trimming function that separates out from among a set of identified anomalies, those that are clearly outliers, rather than ones residing within clusters of anomalies as mapped within an anomalies distribution space. The outlier anomalies are not subjected to a computationally-intensive anomalies aggregating process and thus, processing resources are conserved.

Abstract: The present disclosure is a system for monitoring power that has a unified polyphase distribution transformer monitoring (PDTM) device that interfaces with at least three electrical conductors electrically connected to a transformer. In addition, the PDTM device measures a current and a voltage of each of the three electrical conductors. Additionally, the system has logic that calculates values indicative of power corresponding to the transformer based upon the currents and the voltages measured and transmit data indicative of the calculated values.

Abstract: The present disclosure is a system for monitoring power that has a unified polyphase distribution transformer monitoring (PDTM) device that interfaces with at least three electrical conductors electrically connected to a transformer. In addition, the PDTM device measures a current and a voltage of each of the three electrical conductors. Additionally, the system has logic that calculates values indicative of power corresponding to the transformer based upon the currents and the voltages measured and transmit data indicative of the calculated values.

Abstract: The present disclosure is a system for monitoring power that has a unified polyphase distribution transformer monitoring (PDTM) device that interfaces with at least three electrical conductors electrically connected to a transformer. In addition, the PDTM device measures a current and a voltage of each of the three electrical conductors. Additionally, the system has logic that calculates values indicative of power corresponding to the transformer based upon the currents and the voltages measured and transmit data indicative of the calculated values.

Abstract: Under one aspect, a system includes circuitry that digitizes and Fourier transforms first and second beams and outputs first and second sets of spectral bins. Each bin may include a portion of a group of signals or interference. The circuitry compares the collective power levels of each set of spectral bins to a predetermined threshold, and excises at least one bin of that set that contains the interference if the collective power level of that set exceeds the predetermined threshold. The circuitry determines an angular location of the interference based on excised bins, combines remaining bins with weights selected to form a null in a pattern of the first and second beams that is aligned with the interference's angular location, and inversely Fourier transforms the combined remaining bins and outputs the group of signals less any interference that was excised or excluded by the null.

Abstract: The present disclosure is a system for monitoring power that has a unified polyphase distribution transformer monitoring (PDTM) device that interfaces with at least three electrical conductors electrically connected to a transformer. In addition, the PDTM device measures a current and a voltage of each of the three electrical conductors. Additionally, the system has logic that calculates values indicative of power corresponding to the transformer based upon the currents and the voltages measured and transmit data indicative of the calculated values.

Abstract: Under one aspect of the present invention, a system for processing a group of signals and interference includes (a) an analog-to-digital (A/D) converter for digitizing the group of signals and the interference; (b) a Fourier transform circuit for obtaining a Fourier transform of the digitized group of signals and the interference and to provide as output spectral bins, at least one of which contains the interference; (c) a power analysis circuit for comparing the collective power level of the spectral bins to a predetermined threshold, and if the collective power level exceeds the predetermined threshold, and for excising at least one bin that contains the interference; and (d) an inverse Fourier transform circuit for obtaining an inverse Fourier transform of the remaining spectral bins and outputting a digitized group of signals less the interference in any excised spectral bin.

Abstract: Under one aspect of the present invention, a system for processing a group of signals and interference includes (a) an analog-to-digital (A/D) converter for digitizing the group of signals and the interference; (b) a Fourier transform circuit for obtaining a Fourier transform of the digitized group of signals and the interference and to provide as output spectral bins, at least one of which contains the interference; (c) a power analysis circuit for comparing the collective power level of the spectral bins to a predetermined threshold, and if the collective power level exceeds the predetermined threshold, and for excising at least one bin that contains the interference; and (d) an inverse Fourier transform circuit for obtaining an inverse Fourier transform of the remaining spectral bins and outputting a digitized group of signals less the interference in any excised spectral bin.

Abstract: Under one aspect of the present invention, a system for processing a group of signals and interference includes (a) an analog-to-digital (A/D) converter for digitizing the group of signals and the interference; (b) a Fourier transform circuit for obtaining a Fourier transform of the digitized group of signals and the interference and to provide as output spectral bins, at least one of which contains the interference; (c) a power analysis circuit for comparing the collective power level of the spectral bins to a predetermined threshold, and if the collective power level exceeds the predetermined threshold, and for excising at least one bin that contains the interference; and (d) an inverse Fourier transform circuit for obtaining an inverse Fourier transform of the remaining spectral bins and outputting a digitized group of signals less the interference in any excised spectral bin.

Abstract: A system for monitoring power in accordance with the present disclosure has a first transformer monitoring device that interfaces with a first electrical conductor electrically connected to a transformer at a first location on a power grid. The first transformer measures a first current through the first electrical conductor and a first voltage associated with the first electrical conductor. In addition, the system has a second transformer monitoring device that interfaces with a second electrical conductor electrically connected to the transformer. The second transformer measures a second current through the second electrical conductor and a second voltage associated with the second electrical conductor. Further, the system has logic configured to calculate values indicative of power corresponding to the transformer based upon the first current and the first voltage and the second current and the second voltage.

Abstract: System and method for managing and specifying hardware implementation of a graphical program. A graphical program that implements an algorithm is stored in a memory of a computer system. The graphical program meets one or more first specified implementation requirements and is targeted for deployment to a programmable hardware element. A plurality of sets of descriptive directives are also stored in the memory, where the descriptive directives are associated with the graphical program and specify one or more additional specified implementation requirements, e.g., memory resource implementations, optimization directives, and so forth, where the additional directives result from programmatic and/or user-specification. Each set of descriptive directives is useable by a synthesis tool to generate a respective hardware configuration program for deployment to the graphical programmable hardware element.

Abstract: The present disclosure relates to methods of developing terpene synthase variants through engineered host cells. Particularly, the disclosure provides methods of developing terpene synthase variants with improved in vivo performance that are useful in the commercial production of terpene products. Further encompassed in the present disclosure are superior terpene synthase variants and host cells comprising such terpene synthase variants.