Abstract: An identity certificate may be issued to a blockchain node. The issuance may include issuing a first identity certificate to a first terminal and receiving a second identity certificate issuance request that is from the first terminal. A second identity certificate may be issued to the first terminal, and a third identity certificate issuance request is received from the second terminal. A third identity certificate is issued to the second terminal, so that the second terminal forwards the third identity certificate to the third terminal.

Abstract: Disclosed are a cranial CT-based grading method and a corresponding system, which relate to the field of medical imaging. The cranial CT-based grading method as disclosed solves the problems of relatively great subjective disparities and poor operability in eye-balling ASPECTS assessment. The grading method includes: determining frames where target image slices are located from to-be-processed multi-frame cranial CT data; extracting target areas; performing infarct judgment on each target area included in the target areas to output an infarct judgment outcome regarding the target area; and outputting a grading outcome based on infarct judgment outcomes regarding all target areas.

Abstract: A microprobe is provided that includes a microsphere optical resonator operatively coupled to a nanoscatterer. The microsphere optical resonator includes a back surface and a front surface opposite the front surface. The front surface is configured to receive a focused laser beam, and the nanoscatterer is positioned adjacent to the back surface.

Abstract: A first and a second gate structure each extend in a first direction. A first and a second conductive contact extend in the first direction and are separated from the first and second gate structures in a second direction. A first isolation structure extends in the second direction and separates the first gate structure from the second gate structure. A second isolation structure extends in the second direction and separates the first conductive contact from the second conductive contact. The first gate structure is electrically coupled to a first electrical node. The second gate structure is electrically coupled to a second electrical node different from the first electrical node. The first conductive contact is electrically coupled to the second electrical node. The second conductive contact is electrically coupled to the first electrical node.

Abstract: Described and provided herein are novel antibodies for Claudin 18.2. Also described and provided are pharmaceutical compositions of the antibodies and methods of use for the treatment of cancer.

Abstract: A method of transmitting at least one optical signal through an add-drop filter includes directing the at least one optical signal into a first tapered optical fiber of the add-drop filter. The add-drop filter includes an active resonator side-coupled between the first tapered optical fiber and a second tapered optical fiber, and the active resonator is doped with at least one rare earth ion. A tuned optical gain is produced by delivering a tuned amount of pump laser energy to the at least one rare earth ion at a sub-lasing level, the tuned optical gain configured to compensate an intrinsic loss of the active resonator.

Abstract: An a system and method for chaos transfer between multiple detuned signals in a resonator mediated by chaotic mechanical oscillation induced stochastic resonance where at least one signal is strong and where at least one signal is weak and where the strong and weak signal follow the same route, from periodic oscillations to quasi-periodic and finally to chaotic oscillations, as the strong signal power is increased.

Abstract: An acousto-optic imaging system may include at least one transducer that transmits an ultrasound signal having a fundamental frequency ƒ. The acousto-optic imaging system includes at least one optical sensor that may produce one or more optical responses upon receiving harmonic-related ultrasound echoes corresponding to the transmitted ultrasound signal. For example, the one or more optical sensors may have a bandwidth ranging from at least ƒ/M to Nƒ, where M and N are integers greater than 1.

Abstract: A first and a second gate structure each extend in a first direction. A first and a second conductive contact extend in the first direction and are separated from the first and second gate structures in a second direction. A first isolation structure extends in the second direction and separates the first gate structure from the second gate structure. A second isolation structure extends in the second direction and separates the first conductive contact from the second conductive contact. The first gate structure is electrically coupled to a first electrical node. The second gate structure is electrically coupled to a second electrical node different from the first electrical node. The first conductive contact is electrically coupled to the second electrical node. The second conductive contact is electrically coupled to the first electrical node.

Abstract: An ultrasound device may include ultrasound transducer array that include one or more array elements of a first type and one or more array elements of a second type different from the first type. The first type may include a transducer configured to transmit acoustic waves. The second type may include an optical sensor. The array elements of the first and second types are configured to detect acoustic echoes corresponding to the transmitted acoustic waves.

Abstract: An integrated circuit is disclosed. The integrated circuit includes a first resonator, a second resonator, and a coupling element. The first resonator has a first terminal and a second terminal, where the first resonator comprises a gain resistor, a gain capacitor, and a gain inductor in parallel and electrically coupling the first terminal with the second terminal. The second resonator has a third terminal and a fourth terminal, where the second resonator includes a loss resistor, a loss capacitor, and a loss inductor in parallel and electrically coupling the third terminal with the fourth terminal. The coupling element selectively couples the first terminal of the first resonator with the third terminal of the second resonator.

Abstract: An apparatus may include one or more optical fibers, one or more optical waveguides, and multiple resonator nodes arranged in an array of sensing locations. Each resonator node may include an optical coupling between an optical waveguide and an optical fiber having a set of resonant frequencies at a respective sensing location. Each resonator node may be further configured to communicate a set of signals corresponding to at least one shift in the set of resonant frequencies in the optical fiber at the respective sensing location.

Abstract: Systems and methods for measuring a temperature using an optical whispering gallery mode (WGM) resonator are disclosed. The system includes a WGM resonator operatively coupled to a tunable laser source and a detector, as well as a computing device. The computing device is configured to transform a transmission spectrum from the detector into a measured barcode that includes a matrix of values indicative of at least one characteristic of the transmission spectrum. The computing device is further configured to transform the measured barcode into a temperature based on a relative collective shift of the measured barcode from a reference barcode selected from a predetermined library of reference barcodes.

Abstract: A power supply circuit is configured to supply power to a display panel. The power supply circuit includes a receiver circuit and a transmitter circuit. The receiver circuit is configured to couple the display panel and output a hot plugging signal. The transmitter circuit is configured to receive the hot plugging signal and couple a power circuit. The transmitter circuit is further configured to communicate the receiver circuit to generate an enable signal. The hot plugging signal and the enable signal are configured to control whether a first voltage signal from the power circuit is transmitted to the receiver circuit and the display panel via the transmitter circuit.

Abstract: Described and provided herein are novel antibodies for Claudin 18.2. Also described and provided are pharmaceutical compositions of the antibodies and methods of use for the treatment of cancer.

Abstract: A cerium-zirconium-aluminum-based composite material, a cGPF catalyst and a preparation method thereof are provided. The cerium-zirconium-aluminum-based composite material adopts a stepwise precipitation method, firstly preparing an aluminum-based pre-treated material, then coprecipitating the aluminum-based pre-treated material with zirconium and cerium sol, and finally roasting at high temperature to obtain the cerium-zirconium-aluminum-based composite material. The cerium-zirconium-aluminum-based composite material has better compactness and higher density, and when it is used in cGPF catalyst, it occupies a smaller volume of pores on the catalyst carrier, such that cGPF catalyst has lower back pressure and better ash accumulation resistance, which is beneficial to large-scale application of cGPF catalyst.

Abstract: Sensing apparatuses and method of making the sensing apparatuses are disclosed herein. In some variations, a sensing apparatus can comprise at least one optical waveguide, and at least one whispering gallery mode (WGM) resonator configured to propagate a set of WGMs, where the WGM resonator communicates to the at least one optical waveguide a set of signals corresponding to the set of WGMs. In some variations, a polymer structure may encapsulate the at least one WGM resonator and/or the at least one optical waveguide. Furthermore, in some variations, the WGM resonator(s) may have one or more selectable modes with different bandwidth and sensitivity for sensing, which may, for example, enable tailoring the sensing apparatus to specific applications having certain bandwidth and/or sensitivity requirements.

Abstract: Techniques are described herein that are capable of providing a modularized acoustic probe that includes multiple acoustic transducers that have discrete substrates. A first acoustic transducer is configured to generate an acoustic signal and to transmit the acoustic signal toward an object. The second acoustic transducer is configured to detect a reflected acoustic signal, which results from the acoustic signal reflecting from the object, and to convert the reflected acoustic signal to an electrical signal. The first and second acoustic transducers have respective discrete substrates. In an example, the second acoustic transducer may not be configured to generate acoustic signals. In another example, the first and second acoustic transducers may be in respective first and second rows of a two-row transducer array. In accordance with this example, the first and second acoustic transducers may be designed to have an acoustic parameter having respective first and second parameter values.

Abstract: Optical whispering gallery mode (WGM) resonator-based acoustic sensors, imaging systems that make use of the acoustic sensors, and methods of detecting ultrasound waves using the acoustic sensors are disclosed.

Abstract: Provided is a protein comprising an antibody or antigen-binding fragment and an interleukin molecule operably linked to the antibody or antigen-binding fragment. The antibody or antigen-binding fragment specifically binds to an immune checkpoint protein. The interleukin molecule is IL-10.