Patents by Inventor Lars Adolfsson

Lars Adolfsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11234828
    Abstract: A prosthesis for reconstruction of a distal radioulnar joint, after resection of a part of the ulna, includes a first prosthesis member, fixation members and a second prosthesis member. The first prosthesis member is configured for fixation to the distal end portion of the ulna. The fixation members are configured to extend into the radius via said distal end portion of the ulna for locking said distal end portion of the ulna to the radius. The second prosthesis member is configured for fixation to the ulna close to said distal end portion of the ulna. The second prosthesis member is also configured to extend into said space for being joined with the first prosthesis member in a manner which allows said first and second prosthesis members to at least pivot and rotate relative to each other.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: February 1, 2022
    Assignee: SWEMAC INNOVATION AB
    Inventors: Henrik Hansson, Lars Oster, Michael Ullman, Lars Adolfsson
  • Patent number: 11123466
    Abstract: The present invention is directed to a method for removing cytokines and/or pathogens from blood or blood serum (blood) by contacting the blood with a solid, essentially non microporous substrate which has been surface treated with heparin, heparan sulfate and/or other molecules or chemical groups (the adsorbent media or media) having a binding affinity for the cytokine or pathogen(s) to be removed (the adsorbates), and wherein the size of the interstitial channels within said media is balanced with the amount of media surface area and the surface concentration of binding sites on the media in order to provide adequate adsorptive capacity while also allowing relatively high flow rates of blood through the adsorbent media.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: September 21, 2021
    Assignee: ExThera Medical Corporation
    Inventors: Robert S. Ward, Keith R. McCrea, Olle Larm, Lars Adolfsson
  • Patent number: 10639413
    Abstract: A blood filtration method, system, device and media for removing gram negative bacteria from the blood wherein the media includes a substrate coated with mannose optionally in constitution with substrate coated with heparin.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: May 5, 2020
    Assignee: Exthera Medical Corporation
    Inventors: Keith McCrea, Robert Ward, Olle Larm, Lars Adolfsson
  • Publication number: 20190254833
    Abstract: A prosthesis (1) for reconstruction of a distal radioulnar joint after resection of a part of the ulna close to a distal end portion (U1) thereof, comprises a first prosthesis member (2), fixation means (3) and a second prosthesis member (4). The first prosthesis member (2) is configured for fixation to the distal end portion (U1) of the ulna. The fixation means (3) are configured to extend into the radius via said distal end portion of the ulna for locking said distal end portion of the ulna to the radius. The second prosthesis member (4) is configured for fixation to the ulna (U2) proximally of a space (US) which is defined between the distal end portion (U1) of the ulna and the ulna proximally of said space by the resection of said part of the ulna close to said distal end portion of the ulna.
    Type: Application
    Filed: October 28, 2016
    Publication date: August 22, 2019
    Inventors: Henrik Hansson, Lars Oster, Michael Ullman, Lars Adolfsson
  • Publication number: 20190038826
    Abstract: A blood filtration method, system, device and media for removing gram negative bacteria from the blood wherein the media includes a substrate coated with mannose optionally in constitution with substrate coated with heparin.
    Type: Application
    Filed: August 2, 2018
    Publication date: February 7, 2019
    Applicant: ExThera Medical Corporation
    Inventors: KEITH MCCREA, ROBERT WARD, OLLE LARM, LARS ADOLFSSON
  • Publication number: 20180361050
    Abstract: The present invention is directed to a method for removing cytokines and/or pathogens from blood or blood serum (blood) by contacting the blood with a solid, essentially non micro-porous substrate which has been surface treated with heparin, heparan sulfate and/or other molecules or chemical groups (the adsorbent media or media) having a binding affinity for the cytokine or pathogen(s) to be removed (the adsorbates), and wherein the size of the interstitial channels within said media is balanced with the amount of media surface area and the surface concentration of binding sites on the media in order to provide adequate adsorptive capacity while also allowing relatively high flow rates of blood through the adsorbent media.
    Type: Application
    Filed: August 27, 2018
    Publication date: December 20, 2018
    Applicant: EXTHERA MEDICAL CORPORATION
    Inventors: ROBERT S. WARD, Keith R. McCREA, Olle LARM, Lars ADOLFSSON
  • Patent number: 10086126
    Abstract: The present invention is directed to a method for removing cytokines and/or pathogens from blood or blood serum (blood) by contacting the blood with a solid, essentially non microporous substrate which has been surface treated with heparin, heparan sulfate and/or other molecules or chemical groups (the adsorbent media or media) having a binding affinity for the cytokine or pathogen(s) to be removed (the adsorbates), and wherein the size of the interstitial channels within said media is balanced with the amount of media surface area and the surface concentration of binding sites on the media in order to provide adequate adsorptive capacity while also allowing relatively high flow rates of blood through the adsorbent media.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: October 2, 2018
    Assignee: ExThera Medical Corporation
    Inventors: Robert S Ward, Keith R McCrea, Olle Larm, Lars Adolfsson
  • Patent number: 9669150
    Abstract: The present invention relates to a device for extracorporeal removal of harmful agents from blood or blood com-Components, comprising full length heparin immobilized on a solid substrate by covalent end point attachment. The present invention also relates to a method for extracorporeal removal of a harmful agent from mammalian blood or blood components. The present invention further relates to a process for covalent end point attachment of full length heparin to a solid substrate.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: June 6, 2017
    Assignee: EXTHERA MEDICAL CORPORATION
    Inventors: Olle Larm, Tomas Bergstrom, Jonas Axelsson, Lars Adolfsson, Robert S. Ward, Keith McCrae
  • Publication number: 20160331886
    Abstract: The present invention is directed to a method for removing cytokines and/or pathogens from blood or blood serum (blood) by contacting the blood with a solid, essentially non micro-porous substrate which has been surface treated with heparin, heparan sulfate and/or other molecules or chemical groups (the adsorbent media or media) having a binding affinity for the cytokine or pathogen(s) to be removed (the adsorbates), and wherein the size of the interstitial channels within said media is balanced with the amount of media surface area and the surface concentration of binding sites on the media in order to provide adequate adsorptive capacity while also allowing relatively high flow rates of blood through the adsorbent media.
    Type: Application
    Filed: June 30, 2016
    Publication date: November 17, 2016
    Applicant: EXTHERA MEDICAL CORPORATION
    Inventors: ROBERT S. WARD, Keith R. McCrea, Olle Larm, Lars Adolfsson
  • Patent number: 9408962
    Abstract: The present invention is directed to a method for removing cytokines and/or pathogens from blood or blood serum (blood) by contacting the blood with a solid, essentially non microporous substrate which has been surface treated with heparin, heparan sulfate and/or other molecules or chemical groups (the adsorbent media or media) having a binding affinity for the cytokine or pathogen(s) to be removed (the adsorbates), and wherein the size of the interstitial channels within said media is balanced with the amount of media surface area and the surface concentration of binding sites on the media in order to provide adequate adsorptive capacity while also allowing relatively high flow rates of blood through the adsorbent media.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: August 9, 2016
    Assignee: EXTHERA MEDICAL CORPORATION
    Inventors: Robert S. Ward, Keith R. McCrea, Olle Larm, Lars Adolfsson
  • Publication number: 20160101229
    Abstract: A blood filtration method, system, device and media for removing gram negative bacteria from the blood wherein the media includes a substrate coated with mannose optionally in constitution with substrate coated with heparin.
    Type: Application
    Filed: December 17, 2015
    Publication date: April 14, 2016
    Applicant: EXTHERA MEDICAL CORPORATION
    Inventors: KEITH MCCREA, ROBERT WARD, OLLE LARM, LARS ADOLFSSON
  • Patent number: 8906883
    Abstract: A composition having an ionic complex of chitosan and a negatively charged polysaccharide, selected from the group consisting of heparin, heparan sulfate and dextran sulfate, for use in the treatment of mucositis in a mammalian subject, to a method of preventing or treating mucositis in a mammalian subject, by applying topically a composition having an ionic complex of chitosan and a negatively charged polysaccharide, selected from the group consisting of heparin, heparan sulfate and dextran sulfate. The composition further relates to a pharmaceutical composition for topical administration of an ionic complex of chitosan and heparin.
    Type: Grant
    Filed: June 10, 2010
    Date of Patent: December 9, 2014
    Assignee: Exthera AB
    Inventors: Lars Adolfsson, Olle Larm, Anders Westermark
  • Publication number: 20140231357
    Abstract: The present invention is directed to a method for removing cytokines and/or pathogens from blood or blood serum (blood) by contacting the blood with a solid, essentially non microporous substrate which has been surface treated with heparin, heparan sulfate and/or other molecules or chemical groups (the adsorbent media or media) having a binding affinity for the cytokine or pathogen(s) to be removed (the adsorbates), and wherein the size of the interstitial channels within said media is balanced with the amount of media surface area and the surface concentration of binding sites on the media in order to provide adequate adsorptive capacity while also allowing relatively high flow rates of blood through the adsorbent media.
    Type: Application
    Filed: April 24, 2014
    Publication date: August 21, 2014
    Applicant: EXTHERA MEDICAL CORPORATION
    Inventors: Robert S Ward, Keith R. McCrea, Olle Larm, Lars Adolfsson
  • Patent number: 8758286
    Abstract: The present invention is directed to a method for removing cytokines and/or pathogens from blood or blood serum (blood) by contacting the blood with a solid, essentially non micro-porous substrate which has been surface treated with heparin, heparan sulfate and/or other molecules or chemical groups (the adsorbent media or media) having a binding affinity for the cytokine or pathogen(s) to be removed (the adsorbates), and wherein the size of the interstitial channels within said media is balanced with the amount of media surface area and the surface concentration of binding sites on the media in order to provide adequate adsorptive capacity while also allowing relatively high flow rates of blood through the adsorbent media.
    Type: Grant
    Filed: December 1, 2010
    Date of Patent: June 24, 2014
    Assignee: Exthera Medical Corporation
    Inventors: Robert S Ward, Keith R. McCrea, Olle Larm, Lars Adolfsson
  • Publication number: 20140131276
    Abstract: The present invention relates to a device for extracorporeal removal of harmful agents from blood or blood com-Components, comprising full length heparin immobilized on a solid substrate by covalent end point attachment. The present invention also relates to a method for extracorporeal removal of a harmful agent from mammalian blood or blood components. The present invention further relates to a process for covalent end point attachment of full length heparin to a solid substrate.
    Type: Application
    Filed: January 15, 2014
    Publication date: May 15, 2014
    Inventors: Olle LARM, Tomas Bergström, Jonas AXELSSON, Lars ADOLFSSON, Robert S. WARD, Keith MCCREA
  • Patent number: 8663148
    Abstract: The present invention relates to a device for extracorporeal removal of harmful agents from blood or blood components, comprising full length heparin immobilized on a solid substrate by covalent end point attachment. The present invention also relates to a method for extracorporeal removal of a harmful agent from mammalian blood or blood components. The present invention further relates to a process for covalent end point attachment of full length heparin to a solid substrate.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: March 4, 2014
    Assignee: Exthera Medical Corporation
    Inventors: Olle Larm, Tomas Bergström, Jonas Axelsson, Lars Adolfsson, Robert S. Ward, Keith McCrea
  • Publication number: 20120077773
    Abstract: A composition having an ionic complex of chitosan and a negatively charged polysaccharide, selected from the group consisting of heparin, heparan sulfate and dextran sulfate, for use in the treatment of mucositis in a mammalian subject, to a method of preventing or treating mucositis in a mammalian subject, by applying topically a composition having an ionic complex of chitosan and a negatively charged polysaccharide, selected from the group consisting of heparin, heparan sulfate and dextran sulfate. The composition further relates to a pharmaceutical composition for topical administration of an ionic complex of chitosan and heparin.
    Type: Application
    Filed: June 10, 2010
    Publication date: March 29, 2012
    Applicant: EXTHERA AB
    Inventors: Lars Adolfsson, Olle Larm, Anders Westermark
  • Publication number: 20110184377
    Abstract: The present invention is directed to a method for removing cytokines and/or pathogens from blood or blood serum (blood) by contacting the blood with a solid, essentially non micro-porous substrate which has been surface treated with heparin, heparan sulfate and/or other molecules or chemical groups (the adsorbent media or media) having a binding affinity for the cytokine or pathogen(s) to be removed (the adsorbates), and wherein the size of the interstitial channels within said media is balanced with the amount of media surface area and the surface concentration of binding sites on the media in order to provide adequate adsorptive capacity while also allowing relatively high flow rates of blood through the adsorbent media.
    Type: Application
    Filed: December 1, 2010
    Publication date: July 28, 2011
    Applicant: EXTHERA MEDICAL, LLC
    Inventors: Robert S. WARD, Keith R. MCCREA, Olle Larm, Lars Adolfsson
  • Publication number: 20100249689
    Abstract: The present invention relates to a device for extracorporeal removal of harmful agents from blood or blood components, comprising full length heparin immobilized on a solid substrate by covalent end point attachment. The present invention also relates to a method for extracorporeal removal of a harmful agent from mammalian blood or blood components. The present invention further relates to a process for covalent end point attachment of full length heparin to a solid substrate.
    Type: Application
    Filed: June 18, 2008
    Publication date: September 30, 2010
    Applicant: EXTHERA MEDICAL LLC
    Inventors: Olle Larm, Tomas Bergström, Jones Axelsson, Lars Adolfsson, Robert S. Ward, Keith Mccrea
  • Patent number: 7573892
    Abstract: The invention relates to a switch or router (10) connected to and centrally situated adjacent to a voice over Internet protocol box (22) in a premise connected in a broadband network standard. It comprises an interface (14) to a category infrastructure for distribution of data to flats and offices in premises. The category infrastructure (12, 16) comprises four twisted wire pairs to every flat and office, whereby two pairs are utilized by the broadband standard. Voice over Internet is connected through a first cable interface (50) with multiple connections, and a second cable interface (60) connected and wired together in a registered jack (18, 52) with a category infrastructure. Two of the wire pairs (62) provide two voice over Internet protocol subscription possibilities to every flat and office and two of the broadband connections (64).
    Type: Grant
    Filed: July 11, 2005
    Date of Patent: August 11, 2009
    Assignee: B2 Bredband AB
    Inventor: Lars Adolfsson