Patents by Inventor Lars-Erik Peters

Lars-Erik Peters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6667165
    Abstract: Methods for improving sensitivity and specificity of polynucleotide synthesis are disclosed. The method includes reversibly blocking thermophilic polymerase activity with non-nucleic acid polyanions in a temperature dependent manner. The methods control target specific primer extension throughout all stages of a DNA or RNA amplification reaction. Corresponding compositions and kits are disclosed.
    Type: Grant
    Filed: November 13, 2001
    Date of Patent: December 23, 2003
    Assignee: Eppendorf AG
    Inventor: Lars-Erik Peters
  • Publication number: 20030092135
    Abstract: Methods for improving sensitivity and specificity of polynucleotide synthesis are disclosed. The method includes reversibly blocking thermophilic polymerase activity with non-nucleic acid polyanions in a temperature dependent manner. The methods control target specific primer extension throughout all stages of a DNA or RNA amplification reaction. Corresponding compositions and kits are disclosed.
    Type: Application
    Filed: November 13, 2001
    Publication date: May 15, 2003
    Applicant: Eppendorf AG
    Inventor: Lars-Erik Peters
  • Patent number: 6037465
    Abstract: A universal process is disclosed for extracting and purifying nucleic acids from extremely small amounts of highly contaminated various biological and other starting materials. The invention has applications in forensic medicine, medical diagnosis, molecular biology, biochemistry, genetic technology and all related fields. The process is characterized in that nucleic acid-containing materials are lysed, the lysate is incubated with a non-porous, non-structured, highly disperse, homogeneous and chemically pure SiO.sub.2 substrate, the substrate is isolated with the bound nucleic acids and washed with a buffer solution, then the nucleic acids are dissolved from the substrate by a buffer with a lower salt concentration. Lysis of the material and nucleic acid immobilization are preferably carried out in a reaction vessel. The substrate particles have a size of 7-40 nm, preferably 40 nm, and a specific surface from 50-300 g/m.sup.2, preferably 50 g/m.sup.2.
    Type: Grant
    Filed: December 16, 1996
    Date of Patent: March 14, 2000
    Assignee: Invitek GmbH
    Inventors: Timo Hillebrand, Peter Bendzko, Lars-Erik Peters