Abstract: The present invention pertains to a method for the identification of genetic variants that are associated with the severity of an infectious disease. The invention further pertains to a set of genetic factors associated with the severity of Human respiratory syncytial virus (HRSV) infection, for example in human infants. The genetic polymorphisms identified according to the present invention are for use in the diagnostic of infectious diseases and patient stratification in order to avoid or reduce the occurrence of fatal events during infection or to elect the most appropriate therapeutic approach to treat the disease.

Abstract: The present invention is directed to use of the GLP-1 receptor agonist semaglutide in medical therapy for the treatment of non-alcoholic steatohepatitis.

Abstract: A weighted average execution time associated with each execution stage of a plurality of execution stages used to process a plurality of frames in parallel is obtained. The processing of each of the plurality of frames is performed at each of the plurality of execution stages in a sequential order, starting with an initial execution stage and continuing with each subsequent execution stage. A first largest weighted average execution time associated with one of the plurality of execution stages is determined. A delay to the initial execution stage prior to processing a first next frame is applied. The delay is determined based on the first largest weighted average execution time.

Abstract: Method for registering and updating an electronically stored and versioned alpha digital document (A) in a digital document register by storing, for each version, not the document but a public ownership key; a digital document hash value; and a digital document signature. The invention is characterised by the steps a) providing a first document version, defined in a document description language to have a defined rendered graphic representation; b) registering said first version; c) providing a second document version by adding a reversibly added part to said first document version, said second version comprising a second set of metadata; and d) registering said second version, in that said second metadata is embedded in the second version without affecting said graphic representation, in that at least a part of the reversibly added part can be unambiguously generated based on the second metadata, and in that the registering in step d comprises storing a hash of the second metadata.

Abstract: An adjustable shelf system includes a vertical support member with slots therein, brackets each having at least one rearward hook engageable into a said slot, a shroud behind and about opposing sides of the vertical support member, and a cover member separable into strips configured for placement over the front face of the vertical support member and mateable with the shroud above and below the brackets.

Abstract: An adjustable shelf system includes a vertical support member with slots therein, brackets each having at least one rearward hook engageable into a said slot, a shroud behind and about opposing sides of the vertical support member, and a cover member separable into strips configured for placement over the front face of the vertical support member and mateable with the shroud above and below the brackets.

Abstract: An anchor assembly includes an anchor body for insertion into a wall. A toggle member has an aperture therethrough and is slidable and pivotable relative to the anchor body. The toggle member is configured to have a first position slid forward aligned longitudinally with the anchor body, a second position slid forward and pivoted relative to the anchor body when the fastener engages the toggle member pivoting it relative to the anchor body, and a third position slid rearward and pivoted relative to the anchor body when the fastener enters the toggle member aperture and drives the toggle member rearward to engage the toggle member with the anchor body.

Abstract: Method for registering an electronically stored digital document (A), comprising the steps of a) providing to an owning party a digital document and a private ownership key, which private ownership key is a private key in an asymmetric cryptographic key pair also comprising a corresponding public ownership key; b) calculating a digital document hash value based upon the document (A); c) the owning party using the private ownership key to calculate a digital document signature of the document (A); d) digitally storing in an electronic digital document register not the document (A), but the document signature as well as the public ownership key and the document hash value. The invention also relates to a system.

Abstract: Prediction methods and systems including a central processing unit including a data acquisition unit configured to acquire experimental data of a parameter characterizing the time-dependent phenomenon, a data acquisition unit configured to acquire digital data of the parameter characterizing the phenomenon, and a data processing unit configured to combine the experimental data and the digital data, by using a proper orthogonal decomposition POD that makes it possible to obtain an effective prediction of the time-dependent phenomenon, combining the advantages of the experimental data (accuracy) and those of the digital data (spatial resolution).

Abstract: Method for registering an electronically stored digital document (A), comprising the steps of a) providing to an owning party a digital document and a private ownership key, which private ownership key is a private key in an asymmetric cryptographic key pair also comprising a corresponding public ownership key; b) calculating a digital document hash value based upon the document (A); c) the owning party using the private ownership key to calculate a digital document signature of the document (A); d) digitally storing in an electronic digital document register not the document (A), but the document signature as well as the public ownership key and the document hash value. The invention also relates to a system.

Abstract: An endoscope optic including: an outer tube having an opening at an end face in an end region of the outer tube, a fiber tube disposed in the opening, the fiber tube containing an objective lens, and a fiber bundle for illuminating a region in front of the objective lens, the fiber bundle being provided at an outer periphery of the objective lens, wherein a distal end region of the fiber bundle being arranged in a distal aperture in the fiber tube, the aperture being surrounded by material of the fiber tube.

Abstract: A method of observing a solid sample (100) with a microscope (300), comprising engaging a rotating portion (110) with a first part (104) of the sample (100), holding a second part (106) of the sample (100), and rotating the rotating portion (110) so as to rotate the first part (104) of the sample (100) relative to the second part (106) of the sample (100).

Abstract: A device has a canister for attaching to a fuel container with a wick holder passing through the canister for holding a wick in a position to draw fuel from the reservoir for combustion proximate the top cap. A snuffer in the canister has a sleeve extendible from a first retracted position to a second extended position, the second extended position extending the sleeve partially beyond the wick holder. When the canister is upright the snuffer remains in the first lowered position and when the canister is tilted beyond a predetermined angle the spring moves the sleeve to the second extended position.

Abstract: A self extinguishing torch mechanism has a stationary tube with an opening at an upper end thereof, and a wick tube concentrically rigidly affixed inside the stationary tube defining a space therebetween. A sliding tube is situated coaxially around wick tube the within the space defined between the wick tube and stationary tube. A biasing member extends the sliding member through the opening at the upper end of the stationary tube when the stationary tube is overturned.

Abstract: This invention relates to tubing and a method for heat exchange between a first fluid which is in the tubing and a second tubing which is outside of the tubing. The tubing extends between a first end portion and a second end portion. The tubing includes an inner tube and an outer tube which is arranged on the outside of the inner tube. The inner tube being connected to the outer tube in a fluid-tight manner at the first end portion. The first end portion being surrounded by and attached to a fluid-supply pipe and there being in the second end portion, a passage between the inner tube and the outer tube.

Abstract: A device has a canister for attaching to a fuel container with a wick holder passing through the canister for holding a wick in a position to draw fuel from the reservoir for combustion proximate the top cap. A snuffer in the canister has a sleeve extendible from a first retracted position to a second extended position, the second extended position extending the sleeve partially beyond the wick holder. When the canister is upright the snuffer remains in the first lowered position and when the canister is tilted beyond a predetermined angle the spring moves the sleeve to the second extended position.

Abstract: A device includes a flame bowl with a snuffer sleeve situated therein. The snuffer sleeve has a lowered position allowing a wick to burn freely and a raised position wherein the sleeve impedes oxygen flow to the wick, the snuffer sleeve being biased toward the raised position. A shelf extends from the snuffer sleeve to receive a movable weight that rests on the shelf when the flame bowl is upright and the snuffer sleeve is moved to the lowered position. The movable weight retains the snuffer sleeve in the lowered position while the flame bowl remains upright but moves to allow the snuffer sleeve to extend to the raised position when the flame bowl departs from the upright position more than a predetermined amount.

Abstract: A device has a canister for attaching to a fuel container with a wick holder passing through the canister for holding a wick in a position to draw fuel from the reservoir for combustion proximate the top cap. A snuffer in the canister has a sleeve extendible from a first retracted position to a second extended position, the second extended position extending the sleeve partially beyond the wick holder. When the canister is upright the snuffer remains in the first lowered position and when the canister is tilted beyond a predetermined angle the spring moves the sleeve to the second extended position.

Abstract: A self extinguishing torch mechanism has a stationary tube with an opening at an upper end thereof, and a wick tube concentrically rigidly affixed inside the stationary tube defining a space therebetween. A sliding tube is situated coaxially around wick tube the within the space defined between the wick tube and stationary tube.

Abstract: An endoscope optic including: an outer tube having an opening at an end face in an end region of the outer tube, a fiber tube disposed in the opening, the fiber tube containing an objective lens, and a fiber bundle for illuminating a region in front of the objective lens, the fiber bundle being provided at an outer periphery of the objective lens, wherein a distal end region of the fiber bundle being arranged in a distal aperture in the fiber tube, the aperture being surrounded by material of the fiber tube.