Patents by Inventor Lars Otto Uttenthal

Lars Otto Uttenthal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions comprising granulocyte-macrophage colony-stimulating factor for the treatment of inflammatory bowel disease
    Patent number: 10105415
    Abstract: The present invention provides compositions comprising granulocyte-macrophage colony-stimulating factor and fosfomycin for the treatment, prevention or alleviation of an inflammatory bowel disease such as Crohn's disease, ulcerative colitis or necrotizing enterocolitis of newborn and premature infants by administration of the compositions into the intestinal lumen.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: October 23, 2018
    Assignee: Reponex Pharmaceuticals A/S
    Inventors: Lars Heslet, Lars Otto Uttenthal
  • COMPOSITIONS FOR TREATING LUNG INFECTIONS BY AIRWAY ADMINISTRATION
    Publication number: 20180289773
    Abstract: The present invention provides compositions comprising as an essential feature granulocyte-macrophage colony-stimulating factor (GM-CSF) together with fosfomycin for the treatment of bacterial lung infections by administration via the air-ways.
    Type: Application
    Filed: June 21, 2018
    Publication date: October 11, 2018
    Inventors: Lars Heslet, Lars Otto Uttenthal
  • COMPOSITIONS FOR IMPROVING OR MAINTAINING MYOCARDIAL FUNCTION
    Publication number: 20180200208
    Abstract: Compositions comprising melatonin or derivatives thereof together with coenzyme Q10 and/or alpha-lipoic are provided for oral administration to act as a cardioprotective treatment for heart failure, myocardial ischemia, cardiomyopathies, cardiotoxicity, and in relation to cardiac interventions.
    Type: Application
    Filed: July 19, 2016
    Publication date: July 19, 2018
    Inventor: Lars Otto Uttenthal
  • Methods and Devices for Rapid Assessment of Severity of Injury
    Publication number: 20180172710
    Abstract: Methods and devices for rapid assessment of the severity of injury not due to a natural disease based upon measurement of neutrophil gelatinase-associated lipocalin (NGAL) are provided.
    Type: Application
    Filed: February 6, 2018
    Publication date: June 21, 2018
    Inventors: Kristian BANGERT, Lars Otto UTTENTHAL
  • Methods and devices for rapid assessment of severity of injury
    Patent number: 9927446
    Abstract: Methods and devices for rapid assessment of the severity of injury not due to a natural disease based upon measurement of neutrophil gelatinase-associated lipocalin (NGAL) are provided.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: March 27, 2018
    Assignee: Antibosyshop A/S
    Inventors: Kristian Bangert, Lars Otto Uttenthal
  • Melatonin for Preventing and Treating Radiation Cystitis
    Publication number: 20180055822
    Abstract: Compositions comprising melatonin and/or derivatives thereof are provided for topical administration to the epithelium of the urinary bladder by instillation into the bladder to protect against or treat bladder injury due to irradiation and/or cytotoxic agents.
    Type: Application
    Filed: March 14, 2016
    Publication date: March 1, 2018
    Inventors: Lasse Lindblad, Lars Otto Uttenthal
  • Melatonin for Preventing and Treating Radiation Vaginitis and Proctitis
    Publication number: 20180050019
    Abstract: Compositions comprising melatonin or derivatives thereof are provided for topical administration to the vaginal and/or rectal epithelium to protect against vaginal and/or rectal radiation injury due to radiotherapy.
    Type: Application
    Filed: March 7, 2016
    Publication date: February 22, 2018
    Inventor: Lars Otto Uttenthal
  • Compositions for Preventing and Treating Pulmonary Injury due to Ionizing Radiation or Cytotoxic Drugs
    Publication number: 20180000781
    Abstract: Compositions comprising melatonin or derivatives thereof for administration to the epithelium of the lower airway to protect against lung damage due to chest irradiation and/or cytotoxic chemotherapy are provided.
    Type: Application
    Filed: February 2, 2016
    Publication date: January 4, 2018
    Inventor: Lars Otto Uttenthal
  • COMPOSITIONS FOR THE TREATMENT OF PERITONITIS
    Publication number: 20170232069
    Abstract: The present invention provides compositions comprising granulocyte-macrophage colony-stimulating factor and antimicrobial agents for the treatment, pre-emptive treatment or prevention of infectious peritonitis or intra-abdominal infection by intraperitoneal administration of the compositions.
    Type: Application
    Filed: August 7, 2015
    Publication date: August 17, 2017
    Inventors: Lars Heslet, Lars Otto Uttenthal
  • COMPOSITIONS COMPRISING GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
    Publication number: 20170196937
    Abstract: The present invention provides compositions comprising granulocyte-macrophage colony-stimulating factor and fosfomycin for the treatment, prevention or alleviation of an inflammatory bowel disease such as Crohn's disease, ulcerative colitis or necrotizing enterocolitis of newborn and premature infants by administration of the compositions into the intestinal lumen.
    Type: Application
    Filed: July 24, 2015
    Publication date: July 13, 2017
    Inventors: Lars Heslet, Lars Otto Uttenthal
  • COMPOSITIONS FOR TREATING LUNG INFECTIONS BY AIRWAY ADMINISTRATION
    Publication number: 20170035850
    Abstract: The present invention provides compositions comprising as an essential feature granulocyte-macrophage colony-stimulating factor (GM-CSF) together with fosfomycin for the treatment of bacterial lung infections by administration via the airways.
    Type: Application
    Filed: March 6, 2015
    Publication date: February 9, 2017
    Applicant: Reponex Pharmaceuticals ApS
    Inventors: Lars Heslet, Lars Otto Uttenthal
  • COMPOSITIONS TO PROMOTE THE HEALING OF SKIN ULCERS AND WOUNDS
    Publication number: 20160346354
    Abstract: The present invention provides compositions comprising as an essential feature granulocyte-macrophage colony-stimulating factor (GM-CSF) together with fosfomycin for the treatment of wounds, ulcers, sores, burns and other injuries to the skin or mucous membranes of the body.
    Type: Application
    Filed: February 5, 2015
    Publication date: December 1, 2016
    Inventors: Lars Heslet, Lars Otto Uttenthal
  • Methods for Safe Administration of Nephrotoxic Agents
    Publication number: 20160109463
    Abstract: Methods for determining the risk of developing acute renal failure in a human subject by measuring human neutrophil gelatinase-associated lipocalin (NGAL) are provided.
    Type: Application
    Filed: December 29, 2015
    Publication date: April 21, 2016
    Inventors: Lars Otto UTTENTHAL, Kristian BANGERT
  • Treatment of Acute Tubular Necrosis or Acute Tubule-Interstitial Nephropathy
    Publication number: 20160003851
    Abstract: Methods for treating, monitoring and diagnosing renal disorders including measuring human neutrophil gelatinase-associated lipocalin (NGAL) are provided.
    Type: Application
    Filed: September 16, 2015
    Publication date: January 7, 2016
    Inventors: Lars Otto Uttenthal, Margarita Ghiglione Juanes, Kristian Bangert
  • Methods and Devices for Rapid Assessment of Severity of Injury
    Publication number: 20150323552
    Abstract: Methods and devices for rapid assessment of the severity of injury not due to a natural disease based upon measurement of neutrophil gelatinase-associated lipocalin (NGAL) are provided.
    Type: Application
    Filed: July 17, 2015
    Publication date: November 12, 2015
    Inventors: Kristian Bangert, Lars Otto Uttenthal
  • Determination of Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Diagnostic Marker for Renal Disorders
    Publication number: 20150132772
    Abstract: Methods for diagnosing renal disorders by measuring human neutrophil gelatinase-associated lipocalin (NGAL) are provided.
    Type: Application
    Filed: January 8, 2015
    Publication date: May 14, 2015
    Inventors: Lars Otto Uttenthal, Margarita Ghiglione Juanes, Kristian Bangert
  • Methods and Devices for Rapid Assessment of Severity of Injury
    Publication number: 20150064730
    Abstract: Methods and devices for rapid assessment of the severity of injury not due to a natural disease based upon measurement of neutrophil gelatinase-associated lipocalin (NGAL) are provided.
    Type: Application
    Filed: November 10, 2014
    Publication date: March 5, 2015
    Inventors: Kristian Bangert, Lars Otto Uttenthal
  • Methods for local treatment with factor VII
    Patent number: 8461115
    Abstract: The present invention provides methods for the local treatment of bleeding in a subject and/or reducing unwanted effects associated with the systemic administration of thrombotic agents to a subject, by local administration of FVII to the subject.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: June 11, 2013
    Assignee: Stellaris Pharmaceuticals ApS
    Inventor: Lars Otto Uttenthal
  • Methods for treating local tracheal, bronchial or alveolar bleeding or hemoptysis
    Patent number: 8431535
    Abstract: The present invention provides methods for the local treatment of tracheal, bronchial or alveolar bleeding or hemoptysis and/or reducing unwanted effects associated with systemic administration of thrombotic agents to a subject via intratracheal, intrabronchial or intraalveolar administration of a blood coagulation factor to the subject.
    Type: Grant
    Filed: September 9, 2005
    Date of Patent: April 30, 2013
    Assignee: Hoiberg A/S
    Inventors: Lars Heslet, Lars Otto Uttenthal
  • Diagnostic test for renal injury
    Patent number: 8313919
    Abstract: A method is provided of diagnosing and monitoring acute renal injury leading to acute renal failure in a human or mammalian subject by determining the ratio of the concentration of neutrophil gelatinase-associated lipocalin (NGAL) in urine to that in plasma or serum.
    Type: Grant
    Filed: March 18, 2008
    Date of Patent: November 20, 2012
    Assignee: BioPorto Diagnostics A/S
    Inventors: Lars Otto Uttenthal, Kristian Bangert