Abstract: An interchangeable ring system is provided. The interchangeable ring system includes a shank and a head. The shank includes a receiving hole, and the head includes a peg. The peg is removably inserted into the receiving hole such that the head is secured on the shank. The shank includes a clamp at least partially extending into the receiving hole.

Abstract: A side pocket mandrel for use in a gas lift system is configured to improve the recovery of petroleum fluids from a well. The side pocket mandrel includes an upper assembly joint, a lower assembly joint, and a central portion that has a total length (LT). The side pocket mandrel further comprises a central bore extending through the side pocket mandrel along a central longitudinal axis that extends through the upper and lower assembly joints. The side pocket mandrel further includes a tool channel offset from the central bore and a side pocket tube linearly aligned with the tool channel and configured to receive a gas lift valve. The side pocket mandrel further includes a pair of primary flow blocks that each have a length (LFa) that is at least 35% of the total length (LT) of the central portion of the side pocket mandrel.

Abstract: Examples described herein generally relate to a system and methods for providing a digital therapeutic for treatment of psychological aspects of an oncological condition. The digital therapeutic may generate a user interface on a user device. The user interface includes a fictional health care provider avatar and plurality of fictional patient avatars. Each fictional patient avatar associated with a distinct patient archetype. The digital therapeutic may output a prompt from the fictional health care provider avatar. The digital therapeutic may output an avatar response to the prompt from at least one selected avatar of the plurality of fictional patient avatars based on the distinct patient archetype associated with the selected avatar. The digital therapeutic may receive, from the patient, a patient response to the prompt. The digital therapeutic may select a subsequent prompt or avatar response to output based on the patient response to the prompt.

Abstract: Examples described herein generally relate to a system and methods for registering a user with an online service. An application server receives, from a health care provider, first patient identifying information and second patient identifying information for a new account. The server transmits a message to the patient based on the second patient identifying information, the message including a unique access code for the patient. The server receives, from a client application via a secure link, a user access code and user identifying information. The server verifies that the user access code matches the unique access code and the user identifying information matches the first patient identifying information. The server requests, in response to the verifying, a new username and password via the client application. The server associates the new username and password with the new account, the online service, the first and second patient identifying information.

Abstract: Cells derived from postpartum tissue and methods for their isolation and induction to differentiate to cells of a chondrogenic or osteogenic phenotype are provided by the invention. The invention further provides cultures and compositions of the postpartum-derived cells and products such as lysates related thereto. The postpartum-derived cells of the invention and products related thereto have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications, for example, in the treatment of bone and cartilage conditions such as osteoarthritis.

Abstract: Provided herein are sphingolipid compounds that are useful for activating natural killer T cells. Also provided are methods for treating or preventing a disease or disorder that is treatable by activating the immune system by stimulating natural killer T cells. The compounds are therefore useful for treating or reducing the likelihood of occurrence of an immune diseases and disorders, such as autoimmune diseases or disorders. The compounds may also be used for treating or reducing the likelihood of occurrence of a microbial infection or for treating or reducing the likelihood of occurrence of a cancer in a subject by administering the sphingolipid compounds described herein.

Abstract: Cells derived from postpartum tissue and products thereof having the potential to support cells of and/or differentiate to cells of a soft tissue lineage, and methods of preparation and use of those postpartum tissue-derived cells, are provided by the invention. The invention also provides methods for the use of such postpartum-derived cells and products related thereto in therapies for conditions of soft tissue.

Abstract: A testing apparatus for testing a user's sustained attention comprises at least one stimulus-provider and a controller for controlling the stimulus-provider to provide at least one target stimulus, wherein the controller is configured to perform at least one operating procedure and the or each operating procedure comprises controlling the stimulus-provider to provide a sequence of target stimuli to the user.

Abstract: Provided herein are sphingolipid compounds that are useful for activating natural killer T cells. Also provided are methods for treating or preventing a disease or disorder that is treatable by activating the immune system by stimulating natural killer T cells. The compounds are therefore useful for treating or reducing the likelihood of occurrence of an immune diseases and disorders, such as autoimmune diseases or disorders. The compounds may also be used for treating or reducing the likelihood of occurrence of a microbial infection or for treating or reducing the likelihood of occurrence of a cancer in a subject by administering the sphingolipid compounds described herein.

Abstract: A testing apparatus for testing a user's sustained attention comprises at least one stimulus-provider and a controller for controlling the stimulus-provider to provide at least one target stimulus, wherein the controller is configured to perform at least one operating procedure and the or each operating procedure comprises controlling the stimulus-provider to provide a sequence of target stimuli to the user.

Abstract: Methods are provided for the fabrication of abrupt and tunable offset spacers for improved transistor short channel control. The methods include the formation of a gate electrode within a dielectric layer, with only a top portion of the gate electrode exposed. Silicon is added on the top portion of the gate electrode, by selective epitaxial growth, for example. Etching of the dielectric layer is performed with added silicon at the top portion of the gate electrode serving as a silicon mask to prevent etching of the dielectric layer directly underneath the silicon mask, which includes overhangs over the gate electrode sidewalls. The etching creates offset spacers in a production-worthy manner, and can be used to form offset spacers that are asymmetrical in width. By running the methodology in a microloading regime, wider offset spacers may be created on narrower polysilicon gate features, thereby improving Vt roll-off.

Abstract: Novel sequence tagged sites (STSs), probes and primers useful, e.g., for detecting the presence or absence of an STS in a sample, and methods of using these STSs, probes and primers, e.g., in methods of detecting alterations in the Y chromosome are disclosed. These compositions are also useful in methods of diagnosing or aiding in the diagnosis and/or cause of reduced sperm count and in methods of predicting or aiding in the prediction of the likelihood of success of infertility treatments.

Abstract: Methods are provided for the fabrication of abrupt and tunable offset spacers for improved transistor short channel control. The methods include the formation of a gate electrode within a dielectric layer, with only a top portion of the gate electrode exposed. Silicon is added on the top portion of the gate electrode, by selective epitaxial growth, for example. Etching of the dielectric layer is performed with added silicon at the top portion of the gate electrode serving as a silicon mask to prevent etching of the dielectric layer directly underneath the silicon mask, which includes overhangs over the gate electrode sidewalls. The etching creates offset spacers in a production-worthy manner, and can be used to form offset spacers that are asymmetrical in width. By running the methodology in a microloading regime, wider offset spacers may be created on narrower polysilicon gate features, thereby improving Vt roll-off.

Abstract: The method for forming a semiconductor device arrangement with raised source/drains includes depositing a raised source/drain layer on a substrate, followed by a sacrificial layer on the raised source/drain layer. A trench is formed in the sacrificial layer and the raised source/drain layer, and sidewall spacers are formed within the trench. A replacement gate is formed between the sidewall spacers and the sacrificial layer is removed to expose the raised source/drain regions. The sidewall spacers may then be removed from the sidewalls of the replacement gate, leaving the replacement gate a defined distance from the raised source/drain regions.

Abstract: Cleaning sheets comprise an additive that is selected to enhance the pick up and retention of particulate material from surfaces, while minimizing the amount of residue left on the surface being cleaned. If the type of additive and level of additive on the cleaning sheet are not carefully selected, the sheet will leave a residue on the surface being cleaned resulting in filming and streaking of the surface that is unacceptable to consumers. The additive is preferably selected from the group consisting of a wax, an oil, and mixtures thereof. Cleaning implements comprise a mop head having a resilient bottom surface, a portion of which preferably has a substantially smooth curved profile or crown which engages a removable cleaning sheet.

Abstract: A method of treatment of osteoarthritis is described, where a therapeutically effective amount of a composition having biodegradable microparticles in an aqueous vehicle is delivered into the intra-articular space of a joint. In one aspect, the microparticle-containing composition is injected into the synovial fluid-containing portion of an affected joint.

Abstract: Cleaning sheets comprise an additive that is selected to enhance the pick up and retention of particulate material from surfaces, while minimizing the amount of residue left on the surface being cleaned. If the type of additive and level of additive on the cleaning sheet are not carefully selected, the sheet will leave a residue on the surface being cleaned resulting in filming and streaking of the surface that is unacceptable to consumers. The additive is preferably selected from the group consisting of a wax, an oil, and mixtures thereof. Cleaning implements comprise a mop head having a resilient bottom surface, a portion of which preferably has a substantially smooth curved profile or crown which engages a removable cleaning sheet.

Abstract: Disposable cleaning sheets for removing debris from a surface comprise a substrate and a plurality of protrusions affixed to the substrate, wherein the cleaning sheet is removably attachable to a cleaning implement. The protrusions are preferably hook-shaped. The preferred hook-shaped protrusions can be made of certain thermoplastic resins and can have certain geometric configurations. The protrusions can be affixed to the substrate via a variety of process and are preferably affixed to the substrate in one or more zones of the substrate. Methods of removing debris from a surface comprise contacting the surface with a cleaning sheet of the present invention.

Abstract: Novel sequence tagged sites (STSs), probes and primers useful, e.g., for detecting the presence or absence of an STS in a sample, and methods of using these STSs, probes and primers, e.g., in methods of detecting alterations in the Y chromosome are disclosed. These compositions are also useful in methods of diagnosing or aiding in the diagnosis and/or cause of reduced sperm count and in methods of predicting or aiding in the prediction of the likelihood of success of infertility treatments.

Abstract: Cells derived from postpartum tissue and products thereof having the potential to support cells of and/or differentiate to cells of a soft tissue lineage, and methods of preparation and use of those postpartum tissue-derived cells, are provided by the invention. The invention also provides methods for the use of such postpartum-derived cells and products related thereto in therapies for conditions of soft tissue.