Patents by Inventor Laura A. Brown

Laura A. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of osteochondral diseases using postpartum-derived cells and products thereof
    Publication number: 20060154366
    Abstract: Cells derived from postpartum tissue and methods for their isolation and induction to differentiate to cells of a chondrogenic or osteogenic phenotype are provided by the invention. The invention further provides cultures and compositions of the postpartum-derived cells and products such as lysates related thereto. The postpartum-derived cells of the invention and products related thereto have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications, for example, in the treatment of bone and cartilage conditions such as osteoarthritis.
    Type: Application
    Filed: December 22, 2005
    Publication date: July 13, 2006
    Inventors: Laura Brown, Sridevi Dhanaraj, Agnieszka Seyda
  • Pharmaceutical composition and method for treating a joint-capsule arthropathy
    Publication number: 20060122150
    Abstract: A pharmaceutical composition for use in treating a joint-capsule arthropathy comprising an effective amount of one or more of a locally administered, optionally encapsulated therapeutic agent in admixture with a hyaluronic acid delivery vehicle and a method for use thereof in treating a joint-capsule arthropathy by intra-articular injection.
    Type: Application
    Filed: September 30, 2005
    Publication date: June 8, 2006
    Inventors: Dennis Argentieri, Demetrius Carter, Laura Brown, Jeffrey Geesin, John Siekierka, Han Cui
  • A LOW THERMAL BUDGET (MOL) LINER, A SEMICONDUCTOR DEVICE COMPRISING SAID LINER AND METHOD OF FORMING SAID SEMICONDUCTOR DEVICE
    Publication number: 20050221612
    Abstract: The present invention is directed to a low thermal budget MOL liner to be used in the fabrication of a semiconductor device. The low thermal budget MOL liner of the present invention, which is formed by treating a titanium-deposited layer with an in-situ plasma nitridization step, results in a significantly improved high performance device as the need for the higher thermal annealing process presently used in the making of such devices can be avoided. The present invention is further directed to a method of making the resulting semiconductor device, as well as the semi-conductor device itself.
    Type: Application
    Filed: April 5, 2004
    Publication date: October 6, 2005
    Applicants: INTERNATIONAL BUSINESS MACHINES CORPORATION, ADVANCED MICRO DEVICES, INC.
    Inventors: Laura Brown, Fen Jamin, Kin-Sang Lam, Ying Li, Yun Wang, Horatio Wildman, Kwong Wong
  • Transdiscal administration of cycline compounds
    Publication number: 20050038001
    Abstract: The present invention relates to injecting a cycline compound into a diseased intervertebral disc.
    Type: Application
    Filed: August 13, 2003
    Publication date: February 17, 2005
    Applicant: DePuy Spine, Inc.
    Inventors: Mohamed Attawia, Thomas DiMauro, Hassan Serhan, Melissa Grace, Sudhakar Kadiyala, David Urbahns, Scott Bruder, Gregory Collins, Laura Brown, Jeff Geesin, Pamela Plouhar, Catherine Smith, John Siekierka
  • Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints
    Publication number: 20050025765
    Abstract: The present invention relates to trans-capsularly administering into a diseased joint a high specificity antagonist selected from the group consisting of: i) an inhibitor of a pro-inflammatory interleukin; ii) an inhibitor of TNF-? synthesis; iii) an inhibitor of membrane-bound TNF-?; iv) an inhibitor of a natural receptor of TNF-?; v) an inhibitor of NO synthase, vi) an inhibitor of PLA2 enzyme; vii) an anti-proliferative agent; viii) an anti-oxidant; ix) an apoptosis inhibitor selected from the group consisting of EPO mimetic peptides, EPO mimetibodies, IGF-I, IGF-II, and caspase inhibitors, and x) an inhibitor of MMPs; and xi) an inhibitor of p38 kinase.
    Type: Application
    Filed: July 30, 2003
    Publication date: February 3, 2005
    Applicant: DePuy Spine, Inc.
    Inventors: Thomas DiMauro, Mohamed Attawia, Hassan Serhan, Martin Reynolds, Melissa Grace, Sudhakar Kadiyala, David Urbahns, Scott Bruder, Gregory Collins, Laura Brown, Jeff Geesin, Pamela Plouhar, Catherine Smith, John Siekierka
  • Toilet brush
    Patent number: D318955
    Type: Grant
    Filed: January 22, 1990
    Date of Patent: August 13, 1991
    Inventor: Laura Brown