Patents by Inventor Laura P. W. Ranum

Laura P. W. Ranum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEOTIDE REPEAT EXPANSION-ASSOCIATED POLYPEPTIDES AND USES THEREOF
    Publication number: 20170198020
    Abstract: Isolated polypeptides that are endogenously expressed from nucleotide repeat expansions are disclosed. In some cases, the polypeptides include polypeptide repeats. In some cases, the polypeptide repeats include at least five contiguous repeats of a single amino acid. In other cases, the repeats include at least six contiguous amino acids of a tetra- or penta-amino acid repeat block.
    Type: Application
    Filed: March 21, 2017
    Publication date: July 13, 2017
    Inventors: Laura P.W. Ranum, Tao Zu
  • Spinocerebellar ataxia type 8 and methods of detection
    Patent number: 9556488
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: January 31, 2017
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • NUCLEOTIDE REPEAT EXPANSION-ASSOCIATED POLYPEPTIDES AND USES THEREOF
    Publication number: 20150011729
    Abstract: Isolated polypeptides that are endogenously expressed from nucleotide repeat expansions are disclosed. In some cases, the polypeptides include polypeptide repeats. In some cases, the polypeptide repeats include at least five contiguous repeats of a single amino acid. In other cases, the repeats include at least six contiguous amino acids of a tetra- or penta-amino acid repeat block.
    Type: Application
    Filed: July 7, 2014
    Publication date: January 8, 2015
    Inventors: Laura P.W. Ranum, Tao Zu
  • SPINOCEREBELLAR ATAXIA TYPE 8 AND METHODS OF DETECTION
    Publication number: 20140322711
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Application
    Filed: April 28, 2014
    Publication date: October 30, 2014
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Laura P.W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • Spinocerebellar ataxia type 8 and methods of detection
    Patent number: 8748096
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: June 10, 2014
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • SPINOCEREBELLAR ATAXIA TYPE 8 AND METHODS OF DETECTION
    Publication number: 20130230849
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Application
    Filed: August 20, 2012
    Publication date: September 5, 2013
    Applicant: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • NUCLEOTIDE REPEAT EXPANSION-ASSOCIATED POLYPEPTIDES AND USES THEREOF
    Publication number: 20130115603
    Abstract: Isolated polypeptides that are endogenously expressed from nucleotide repeat expansions are disclosed. In some cases, the polypeptides include polypeptide repeats. In some cases, the polypeptide repeats include at least five contiguous repeats of a single amino acid. In other cases, the repeats include at least six contiguous amino acids of a tetra- or penta-amino acid repeat block.
    Type: Application
    Filed: April 1, 2010
    Publication date: May 9, 2013
    Applicant: Regents of the University of Minnesota
    Inventors: Laura P.W. Ranum, Tao Zu
  • SPINOCEREBELLAR ATAXIA TYPE 8 AND METHODS OF DETECTION
    Publication number: 20130029335
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Application
    Filed: August 20, 2012
    Publication date: January 31, 2013
    Applicant: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • Spinocerebellar ataxia type 8 and methods of detection
    Patent number: 8247173
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Grant
    Filed: June 21, 2010
    Date of Patent: August 21, 2012
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • NUCLEOTIDE REPEAT EXPANSION-ASSOCIATED POLYPEPTIDES AND USES THEREOF
    Publication number: 20120094299
    Abstract: Isolated polypeptides that are endogenously expressed from nucleotide repeat expansions are disclosed. In some cases, the polypeptides include polypeptide repeats. In some cases, the polypeptide repeats include at least five contiguous repeats of a single amino acid. In other cases, the repeats include at least six contiguous amino acids of a tetra- or penta-amino acid repeat block.
    Type: Application
    Filed: April 1, 2010
    Publication date: April 19, 2012
    Applicant: Regents of the University of Minnesota
    Inventors: Laura P.W. Ranum, Tao Zu
  • SPINOCEREBELLAR ATAXIA TYPE 8 AND METHODS OF DETECTION
    Publication number: 20100317015
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Application
    Filed: June 21, 2010
    Publication date: December 16, 2010
    Applicant: Regents of the University of Minnesota
    Inventors: LAURA P.W. RANUM, MICHAEL D. KOOB, KELLIE A. BENZOW, MELINDA L. MOSELEY-ALLDREDGE
  • Spinocerebellar ataxia type 8 and methods of detection
    Patent number: 7741458
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Grant
    Filed: February 24, 2003
    Date of Patent: June 22, 2010
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • Identification of a gene associated with spinocerebellar ataxia type 5 and methods of use
    Patent number: 7527931
    Abstract: The present invention provides methods that include analyzing an SCA5 polynucleotide, and determining whether the SCA5 polynucleotide includes a mutation. The methods may be used to identify a subject that is at risk or not at risk for developing spinocerebellar ataxia type 5. The present invention also provides isolated polynucleotides having a mutation present in an SCA5 polynucleotide.
    Type: Grant
    Filed: February 22, 2006
    Date of Patent: May 5, 2009
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Yoshio Ikeda, Katherine A. Dick, John W. Day, Lawrence J. Schut
  • Intron associated with myotonic dystrophy type 2 and methods of use
    Patent number: 7442782
    Abstract: The present invention provides methods for identifying individuals not at risk for developing myotonic dystrophy type 2 (DM2), and individuals that have or at risk for developing DM2. The present invention also provides isolated polynucleotides that include a repeat tract within intron 1 of the zinc finger protein 9.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: October 28, 2008
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, John W. Day, Christina Liquori
  • SCA7 gene and methods of use
    Patent number: 7118893
    Abstract: The present invention provides diagnostic methods of identifying individuals at risk and not at risk of developing spinocerebellar ataxia type 7. The present invention also provides for methods for identifying expanded repeats, and the DNA flanking the expanded repeats, from genomic DNA.
    Type: Grant
    Filed: February 3, 2003
    Date of Patent: October 10, 2006
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Melinda L. Moseley-Alldredge, Kellie A. Benzow
  • Intron associated with myotonic dystrophy type 2 and methods of use
    Patent number: 6902896
    Abstract: The present invention provides methods for identifying individuals not at risk for developing myotonic dystrophy type 2 (DM2), and individuals that have or are at risk for developing DM2. The present invention also provides isolated polynucleotides that include a repeat tract within intron 1 of the zinc finger protein 9.
    Type: Grant
    Filed: May 10, 2002
    Date of Patent: June 7, 2005
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, John W. Day, Christina Liquori
  • Spinocerebellar ataxia type 8 and methods of detection
    Publication number: 20030235841
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Application
    Filed: February 24, 2003
    Publication date: December 25, 2003
    Applicant: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • SCA7 gene and methods of use
    Publication number: 20030180768
    Abstract: The present invention provides diagnostic methods of identifying individuals at risk and not at risk of developing spinocerebellar ataxia type 7. The present invention also provides for methods for identifying expanded repeats, and the DNA flanking the expanded repeats, from genomic DNA.
    Type: Application
    Filed: February 3, 2003
    Publication date: September 25, 2003
    Applicant: Regents of the University of Minnesota
    Inventors: Laura P.W. Ranum, Michael D. Koob, Melinda L. Moseley-Alldredge, Kellie A. Benzow
  • Intron associated with myotonic dystrophy type 2 and methods of use
    Publication number: 20030108887
    Abstract: The present invention provides methods for identifying individuals not at risk for developing myotonic dystrophy type 2 (DM2), and individuals that have or at risk for developing DM2. The present invention also provides isolated polynucleotides that include a repeat tract within intron 1 of the zinc finger protein 9.
    Type: Application
    Filed: May 10, 2002
    Publication date: June 12, 2003
    Inventors: Laura P.W. Ranum, John W. Day, Christina Liquori
  • Spinocerebellar ataxia type 8 and methods of detection
    Patent number: 6524791
    Abstract: The present invention provides an isolated nucleic acid molecule containing a a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Grant
    Filed: October 28, 1998
    Date of Patent: February 25, 2003
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge