Patents by Inventor Laura P. W. Ranum

Laura P. W. Ranum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SCA7 gene and methods of use
    Patent number: 6514755
    Abstract: The present invention provides diagnostic methods of identifying individuals at risk and not at risk of developing spinocerebellar ataxia type 7. The present invention also provides for methods for identifying expanded repeats, and the DNA flanking the expanded repeats, from genomic DNA.
    Type: Grant
    Filed: October 6, 2000
    Date of Patent: February 4, 2003
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Melinda L. Mosely-Alldredge, Kellie A. Benzow
  • SCA7 gene and method of use
    Patent number: 6280938
    Abstract: The present invention provides diagnostic methods of identifying individuals at risk and not at risk of developing spinocerebellar ataxia type 7. The present invention also provides for methods for identifying expanded repeats, and the DNA flanking the expanded repeats, from genomic DNA.
    Type: Grant
    Filed: August 18, 1998
    Date of Patent: August 28, 2001
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Melinda L. Moseley-Alldredge, Kellie A. Benzow
  • Gene sequence for spinocerebellar ataxia type 1 and method for diagnosis
    Patent number: 5834183
    Abstract: The present invention provides an isolated DNA molecule of the autosomal dominant spinocerebellar ataxia type 1 gene, which is located within the short arm of chromosome 6. This isolated DNA molecule is preferably located within a 3.36 kb EcoRI fragment, i.e., an EcoRI fragment containing about 3360 base pairs, of the SCA1 gene. The isolated sequences contain a CAG repeat region. The number of CAG trinucleotide repeats (n) is .ltoreq.36, preferably n=19-36, for normal individuals. For an affected individual n>36, preferably n.gtoreq.43.
    Type: Grant
    Filed: June 28, 1994
    Date of Patent: November 10, 1998
    Assignee: Regents of the University of Minnesota
    Inventors: Harry T. Orr, Laura P. W. Ranum, Ming-yi Chung, Huda Y. Zoghbi
  • Gene sequence for spinocerebellar ataxia type 1 and method for diagnosis
    Patent number: 5741645
    Abstract: The present invention provides an isolated DNA sequence of the short arm of chromosome 6 which is located within the autosomal dominant spinocerebellar ataxia type 1 gene. This isolated DNA sequence is preferably located within a 3.36 kb EcoRI fragment, i.e., an EcoRI fragment containing about 3360 base pairs, of the SCA1 gene. The isolated sequence preferably contains a CAG repeat region. The number of CAG trinucleotide repeats (n) is.ltoreq.36, preferably n=19-36, for normal individuals. For an affected individual n>36, preferably n.gtoreq.43.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: April 21, 1998
    Assignee: Regents of the University of Minnesota
    Inventors: Harry T. Orr, Laura P. W. Ranum, Ming-Yi Chung, Huda Y. Zoghbi