Abstract: Nasal cannula assemblies for providing respiratory therapy to patients are provided. A nasal cannula assembly can include a cannula, an optional manifold which may be removable, a gas supply tube, and a securement mechanism. Securement mechanisms can include headgear straps, cheek pads, or an adhesive nose strip. A nasal cannula assembly can also include a lanyard, lanyard clip, and/or lanyard connector to help support the weight of a main gas delivery conduit.

Abstract: There is disclosed system for oxygenating a patient in relation to anaesthesia using high flow gas delivery. The system has a flow source, and a controller for determining oxygenation requirements of the patient before or during anaesthesia. A method of oxygenating a patient in relation to anaesthesia using high flow gas delivery is also disclosed. The method determines oxygenation requirements of the patient before or during anaesthesia.

Abstract: A suspension system for supporting a body relative to at least four points, including: a respective front left, front right, back left and back right support arrangement between the respective point and the body, each respective support arrangement including a respective resilience arrangement and a respective control ram, each respective control ram including a respective compression chamber forming at least part of a respective compression control volume; a control arrangement including a first and a second diagonal reversible pump for displacing fluid between diagonally opposite compression control volumes. Each respective resilience arrangement can include a respective damping arrangement to restrict and/or selectively prevent compression and/or expansion of at least a portion of the respective resilience arrangement. Each respective control ram can further include a respective rebound chamber, the front control rams being cross connected and the back control rams being cross connected.

Abstract: The present invention provides methods of treating glioblastoma by administering an adenoviral vector that conditionally expresses IL-12 via gene switch under control of an oral activator ligand.

Abstract: A method, system, and computer program product for enabling a digital search is provided. The method includes monitoring, in response to receiving authorization from a user, Web search results of a user, social media accounts, and media sources. In response data indicating an importance of world related factors with respect to the user is received. The data is analyzed with respect to results of the monitoring and an associated metadata model and modeling software application personalized for the user is generated. A search request associated with initiating a Web search for a product or service is initiated and the modeling software application is executed with respect to the metadata model and Web search. Personalized Web search results are generated and presented to the user. The personalized Web search results indicate entities associated with providing the product or service for the user via Internet based commerce Websites.

Abstract: An improved article of footwear of the invention includes an upper, an adjustable closure system affixed to the upper, the closure system having a guide member having a first groove portion and a second groove portion, a fastening member positioned opposite the guide member and having at least two tensioning members, and removable cable assembly connecting the guide member and the fastening member, wherein the cable assembly extends sequentially through the first groove portion of the guide member, a first tensioning member of the fastening member, the second groove portion of the guide member, and a second tensioning member of the fastening member, a bottom secured to the upper, a stabilizing member positioned between the upper and the bottom, wherein the stabilizing member has a base portion and at least one of a lateral support portion and a medial support portion extending upwardly from opposing sides of the base portion.

Abstract: A method, system, and computer program product for enabling a digital search is provided. The method includes monitoring, in response to receiving authorization from a user, Web search results of a user, social media accounts, and media sources. In response data indicating an importance of world related factors with respect to the user is received. The data is analyzed with respect to results of the monitoring and an associated metadata model and modeling software application personalized for the user is generated. A search request associated with initiating a Web search for a product or service is initiated and the modeling software application is executed with respect to the metadata model and Web search. Personalized Web search results are generated and presented to the user. The personalized Web search results indicate entities associated with providing the product or service for the user via Internet based commerce Websites.

Abstract: Systems, methods, computer-readable medium, vehicles, and engines provided herein include or implement flexible engine monitoring features. In one aspect, a user-modifiable file containing selected parameters is uploaded to a vehicle having a propulsion system, such as an engine. A computing device associated with the engine generates, without modifying reporting software or any other software, a parameter reporting list that includes the selected parameters. During operation, parameter values for the selected parameters are recorded. In another aspect, a data query is transmitted to an aerial vehicle while in-flight. The data query includes a user-modifiable file that contains selected parameters for which parameter values are to be recorded. A computing device associated with the engine generates, without modifying reporting software or any other software, a parameter reporting list that includes the selected parameters.

Abstract: An improved article of footwear of the invention includes an upper, an adjustable closure system affixed to the upper, the closure system having a guide member having a first groove portion and a second groove portion, a fastening member positioned opposite the guide member and having at least two tensioning members, and removable cable assembly connecting the guide member and the fastening member, wherein the cable assembly extends sequentially through the first groove portion of the guide member, a first tensioning member of the fastening member, the second groove portion of the guide member, and a second tensioning member of the fastening member, a bottom secured to the upper, a stabilizing member positioned between the upper and the bottom, wherein the stabilizing member has a base portion and at least one of a lateral support portion and a medial support portion extending upwardly from opposing sides of the base portion.

Abstract: A method of attaching an adapter to a polynucleotide comprising: providing a double stranded polynucleotide comprising a single stranded break point within its polynucleotide sequence; contacting said double stranded polynucleotide with an exonuclease to form a single stranded region initiated at said break point; attaching an adapter to said single stranded region.

Abstract: An assembly for use in an electrical power distribution system includes a housing that includes an interior space; an electrical apparatus in the interior space, the electrical apparatus including an electrical connection mechanism that is configured to move between at least two positions; an observation port through the housing, the observation port being configured to allow visual observation of the electrical connection mechanism in the interior space from an exterior of the housing; and an optical guide between the interior space and a light source. The light source is outside of the interior space and the optical guide is configured to deliver light from the light source to the interior space when the light source emits light.

Abstract: An improved article of footwear of the invention includes an upper, an adjustable closure system affixed to the upper, the closure system having a guide member having a first groove portion and a second groove portion, a fastening member positioned opposite the guide member and having at least two tensioning members, and removable cable assembly connecting the guide member and the fastening member, wherein the cable assembly extends sequentially through the first groove portion of the guide member, a first tensioning member of the fastening member, the second groove portion of the guide member, and a second tensioning member of the fastening member, a bottom secured to the upper, a stabilizing member positioned between the upper and the bottom, wherein the stabilizing member has a base portion and at least one of a lateral support portion and a medial support portion extending upwardly from opposing sides of the base portion.

Abstract: A toy construction system comprising toy construction elements comprising coupling members (20) for detachably interconnecting the toy construction elements to create spatial structures (40), the toy construction system comprises at least a first type of toy construction elements (10), the first type of toy construction elements can be coupled to each other, wherein that the first type of toy construction elements is configured to be detected by a touch screen (60), and when toy construction elements are coupled to each other so as to form a spatial structure, the toy construction elements of the first type define a touch point pattern recognizable by the touch screen.

Abstract: An assembly for use in an electrical power distribution system includes a housing that includes an interior space; an electrical apparatus in the interior space, the electrical apparatus including an electrical connection mechanism that is configured to move between at least two positions; an observation port through the housing, the observation port being configured to allow visual observation of the electrical connection mechanism in the interior space from an exterior of the housing; and an optical guide between the interior space and a light source. The light source is outside of the interior space and the optical guide is configured to deliver light from the light source to the interior space when the light source emits light.

Abstract: An improved article of footwear of the invention includes an upper, an adjustable closure system affixed to the upper, the closure system having a guide member having a first groove portion and a second groove portion, a fastening member positioned opposite the guide member and having at least two tensioning members, and removable cable assembly connecting the guide member and the fastening member, wherein the cable assembly extends sequentially through the first groove portion of the guide member, a first tensioning member of the fastening member, the second groove portion of the guide member, and a second tensioning member of the fastening member, a bottom secured to the upper, a stabilizing member positioned between the upper and the bottom, wherein the stabilizing member has a base portion and at least one of a lateral support portion and a medial support portion extending upwardly from opposing sides of the base portion.

Abstract: There is provided an optical fiber for providing increased sensitivity in sensing applications by increasing the Rayleigh backscatter coefficient of the fiber while maintaining tolerable levels of signal attenuation (e.g., less than 20% over 10 km). Such an optical fiber comprises a core, a first cladding layer and a second cladding layer. The core comprises at least one core dopant selected from the range of: germanium, phosphorus, aluminium, boron, fluorine. The at least one core dopant is used to increase the core refractive index and enhance the core Rayleigh backscatter coefficient. The first cladding layer comprises at least one dopant selected from: germanium, phosphorus, aluminium, boron, fluorine; wherein at least one first cladding layer dopant is used to reduce the first cladding layer refractive index. The signal attenuation generated in the fiber is less than 20% over 1 km.

Abstract: A toy construction system comprising toy construction elements comprising coupling members (20) for detachably interconnecting the toy construction elements to create spatial structures (40), the toy construction system comprises at least a first type of toy construction elements (10), the first type of toy construction elements can be coupled to each other, wherein that the first type of toy construction elements is configured to be detected by a touch screen (60), and when toy construction elements are coupled to each other so as to form a spatial structure, the toy construction elements of the first type define a touch point pattern recognizable by the touch screen.

Abstract: An insulated switchgear module is disclosed. In one example, the module comprises a vacuum interrupter, current exchange assembly, and end conductors disposed within an insulated housing. The insulated housing further comprises a tank containing an actuator mechanism for actuating the current exchange assembly. An insulating tray within the housing separates the vacuum interrupter from the components in the tank. The insulated tray has a shape that corresponds with the shape of the vacuum interrupter and the shape of the housing.

Abstract: An example method includes introducing a movable inline inspection device into a pipeline, the movable inline inspection device having a housing that defines a conduit therein which provides fluid communication through the movable inline inspection device in the form of a bypass fluid, the conduit having one or more optical computing devices arranged thereon for monitoring the bypass fluid, wherein each optical computing device has at least one integrated computational element arranged therein, generating an output signal corresponding to a characteristic of the bypass fluid with at least one detector arranged within each optical computing device, receiving the output signal from each optical computing device with a signal processor communicably coupled to the at least one detector of each optical computing device, and determining with the signal processor the characteristic of the bypass fluid detected by each optical computing device.