Abstract: Systems, apparatus and methods are provided for the real-time positional manipulation of stereoscopic (3D) subtitles in a stereoscopic viewing environment. A stereoscopic subtitling workstation is provided for creating stereoscopic subtitling content for use with stereoscopic video content in which stereoscopic subtitling content can be manipulated and adjusted in real-time in a stereoscopic viewing environment to set the desired viewing position and appearance parameters for the stereoscopic subtitling content. The stereoscopic subtitling workstation may further automatically analyze the stereoscopic video content and automatically generate optimal viewing parameters for the stereoscopic subtitling content, including its 3D offset, according to desired appearances and interaction between such content.

Abstract: A method of servicing subsea equipment comprising positioning a reaction chamber about the subsea equipment having a plug therein, wherein positioning the reaction chamber substantially isolates an area about the subsea equipment from an environment external to the reaction chamber, providing one or more reactants to the reaction chamber, and allowing a reaction to proceed between the reactants, wherein the reaction produces sufficient heat to eliminate the plug. A system for removing plugs from subsea equipment comprising a support vessel, a reaction chamber supported by the support vessel and positioned adjacent the subsea equipment having a plug therein, wherein the reaction chamber is configured to substantially isolate an area about the subsea equipment having a plug therein from an environment external to the reaction chamber, and one or more exothermically-reacting chemical reactants present within the reaction chamber.

Abstract: Compounds of the formula (I): wherein R1, R2, R4 and R13 are as defined or a pharmaceutically or veterinarily acceptable salt or polymorph thereof, or a pharmaceutically or veterinarily acceptable solvate or pro-drug thereof: are potent and selective inhibitors of type 5 cyclic guanosine 3?,5?-monophosphate phosphodiesterase (cGMP PDE5) and have utility in the treatment of, inter alia, male erectile dysfunction (MED) and female sexual dysfunction (FSD).

Abstract: A process for the preparation of Compounds of the formula (1): wherein R1, R2, R4 and R13 are as defined or a pharmaceutically or veterinarily acceptable salt or polymorph thereof, or a pharmaceutically or veterinarily acceptable solvate or pro-drug thereof: are potent and selective inhibitors of type 5 cyclic guanosine 3?,5?-monophosphate phosphodiestbrase (cGMP PDE5) and have utility in the treatment of, inter alia, male erectile dysfunction (MED) and female sexual dysfunction (FSD).

Abstract: A computer mouse 10 has magnetic orientation features. It comprises a body 11 in which is located a mechanism 13 for sensing the x and y movement of the body and a compassing device 16 for determining the magnetic orientation of the body. The mouse has a processor 40 for receiving and processing x and y movement data and magnetic orientation data. The processor sends the processed data to a transmitter 15 located in the body. The transmitter is wireless and sends signals based on the x and y data and the magnetic orientation data in real time.

Abstract: A process is provide for the preparation of compounds of formula (I) herein comprising reacting a compound of formula (III), (IV) or (V) wherein the variables are as defined in the specification. The reaction is conducted in the presence of −OR3 and a hydroxide trapping agent or in the case of compounds of formula (IV) reacting in the presence of an auxiliary base and a hydroxide trapping agent.

Abstract: Compounds of the formula (1): 1

Abstract: A computer mouse 10 has magnetic orientation features. It comprises a body 11 in which is located a mechanism 13 for sensing the x and y movement of the body and a compassing device 16 for determining the magnetic orientation of the body. The mouse has a processor 40 for receiving and processing x and y movement data and magnetic orientation data. The processor sends the processed data to a transmitter 15 located in the body. The transmitter is wireless and sends signals based on the x and y data and the magnetic orientation data in real time.

Abstract: An automotive hinge facilitates substantially rotary motion of a closure panel relative to a fixed body structure by means of a single resilient member configured to carry all required structural and operational loadings.

Abstract: A “one-pot” process is described herein for the production of pyrazole compounds of general formula (II) comprising the steps of reacting a compound of general formula (III) with an acylating agent in the presence of a base and an optional activating agent followed by the addition of a hydrazine compound in situ.

Abstract: Compounds of the formula (I): wherein R1, R2, R4 and R13 are as defined or a pharmaceutically or veterinarily acceptable salt or polymorph thereof, or a pharmaceutically or veterinarily acceptable solvate or pro-drug thereof: are potent and selective inhibitors of type 5 cyclic guanosine 3′,5′-monophosphate phosphodiesterase (cGMP PDE5) and have utility in the treatment of, inter alia, male erectile dysfunction (MED) and female sexual dysfunction (FSD).

Abstract: A “one-pot” process is described herein for the production of pyrazole compounds of general formula (II) 1

Abstract: An automatic suspension lockout assembly for bicycles comprises a pedal, crankarm, chainwheel, crankshaft and bearing assembly compliantly mounted to a frame such that a combination of pedaling forces and uphill bicycle inclination creates a small motion suitable for controlling a hydraulic valve in a shock absorber of the bicycle suspension assembly resulting in lockout of the suspension.

Abstract: A “one-pot” process is described herein for the production of pyrazole compounds of general formula (II) 1

Abstract: A polymorph of 1-{6-ethoxy-5-[3-ethyl-6,7-dihydro-2-(2-methoxyethyl)-7-oxo-2H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-pyridylsulfonyl}-4-ethylpiperazine.

Abstract: A “one-pot” process is described herein for the production of pyrazole compounds of general formula (II) comprising the steps of reacting a compound of general formula (III) with an acylating agent in the presence of a base and an optional activating agent followed by the addition of a hydrazine compound in situ.

Abstract: A polymorph of 1-{6-ethoxy-5-[3-ethyl-6,7-dihydro-2-(2-methoxyethyl)-7-oxo-2H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-pyridylsulfonyl}-4-ethylpiperazine.

Abstract: A process is provided for the preparation of compounds of formula (I) herein comprising reacting a compound of formula (II), (III), (IV) or (V) in the presence of −OR3 and a hydroxide trapping agent or in the case of compounds of formula (IV) reacting in the presence of an auxiliary base and a hydroxide trapping agent (i.e. −OR3 is substituted by the auxiliary base), wherein X is a leaving group and R1 to R4 are as defined.

Abstract: A “one-pot” process is described herein for the production of pyrazole compounds of general formula (II) 1

Abstract: An automotive hinge facilitates substantially rotary motion of a closure panel relative to a fixed body structure by means of a single resilient member configured to carry all required structural and operational loadings.