Patents by Inventor Laurence Zitvogel

Laurence Zitvogel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of Cancer Using Tlr3 Agonists
    Publication number: 20080317811
    Abstract: The present invention relates generally to the fields of genetics and medicine. More specifically, the present invention relates to improved methods of treating cancers using a TLR3 agonist, by assessing the expression of TLR3 receptor by cancer cells.
    Type: Application
    Filed: November 18, 2005
    Publication date: December 25, 2008
    Applicant: Institut Gustave Roussy
    Inventors: Fabrice Andre, Laurence Zitvogel, Jean-Christophe Sabourin
  • TREATMENT OF CANCER USING TLR3 AGONISTS
    Publication number: 20080253998
    Abstract: The present invention relates generally to the fields of genetics and medicine. More specifically, the present invention relates to improved methods of treating cancers using a TLR3 agonist, by assessing the expression of a TLR3 receptor by cancer cells.
    Type: Application
    Filed: May 19, 2008
    Publication date: October 16, 2008
    Applicant: INSTITUT GUSTAVE ROUSSY
    Inventors: FABRICE ANDRE, Laurence Zitvogel, Jean-Christophe Sabourin
  • Treatment of cancer using TLR3 agonists
    Patent number: 7378249
    Abstract: The present invention relates generally to the fields of genetics and medicine. More specifically, the present invention relates to improved methods of treating cancers using a TLR3 agonist, by assessing the expression of a TLR3 receptor by cancer cells.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: May 27, 2008
    Assignee: Institut Gustave Roussy
    Inventors: Fabrice Andre, Laurence Zitvogel, Jean-Christophe Sabourin
  • Treatment of cancer using TLR3 agonists
    Publication number: 20060110746
    Abstract: The present invention relates generally to the fields of genetics and medicine. More specifically, the present invention relates to improved methods of treating cancers using a TLR3 agonist, by assessing the expression of a TLR3 receptor by cancer cells.
    Type: Application
    Filed: June 3, 2005
    Publication date: May 25, 2006
    Applicant: Institut Gustave Roussy
    Inventors: Fabrice Andre, Laurence Zitvogel, Jean-Christophe Sabourin
  • Methods for activating natural killer (NK) cells and means for carrying out said methods
    Patent number: 6849452
    Abstract: The present invention relates to a process for activating natural killer cells comprising bringing NK cells into contact with dendritic cells in vitro, ex vivo or in vivo. The invention also relates to cell compositions comprising activated NK cells, NK cell-dendritic cell co-cultures or dendritic cells, and to their use to stimulate the cytolytic activity of NK cells or natural immunity in vivo. The invention also relates to a NK cell stimulation factor present in the dendritic cell membrane, and to triggering media and factor(s) for dendritic cells and to their use, either alone or in combination, to stimulate NK activity, in particular in vivo. The invention can be used to control NK cell activity in vitro, ex vivo or in vivo, in particular under pathological conditions.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: February 1, 2005
    Assignee: Institut Gustave Roussy
    Inventors: Laurence Zitvogel, Nadine Fernandez
  • Sensitization process for antigen-presenting cells and means for implementing the process
    Publication number: 20040028692
    Abstract: The object of the invention is a novel sensitization process for antigen-presenting cells, novel means for implementing the process and novel membrane vesicles possessing immunogenic potency. The invention relates in particular to texosomes (vesicles derived from tumor cells) and dexosomes (vesicles derived from dendritic cells loaded or not with antigens), and their use for the vectorization and presentation of antigens in vitro or in vivo as well as in methods or compositions for the treatment of cancers and infectious, parasitic or autoimmune diseases in particular.
    Type: Application
    Filed: July 2, 2003
    Publication date: February 12, 2004
    Inventors: Laurence Zitvogel, Graca Raposo, Armelle Regnault, Sebastian Amigorena
  • Sensitization process for antigen-presenting cells and means for implementing the process
    Patent number: 6685911
    Abstract: The object of the invention is a novel sensitization process for antigen-presenting cells, novel means for implementing the process and novel membrane vesicles possessing immunogenic potency. The invention relates in particular to texosomes (vesicles derived from tumor cells) and dexosomes (vesicles derived from dendritic cells loaded or not with antigens), and their use for the vectorization and presentation of antigens in vitro or in vivo as well as in methods or compositions for the treatment of cancers and infectious, parasitic or autoimmune diseases in particular.
    Type: Grant
    Filed: March 15, 1999
    Date of Patent: February 3, 2004
    Assignees: Institut National de la Sante et de la Recherche Medicale, Institut Gustave Roussy, Centre National de la Recherche Scientifique, Institut Curie
    Inventors: Laurence Zitvogel, Graça Raposo, Armelle Regnault, Sebastian Amigorena