Abstract: The present disclosure pertains to a portable handheld pressure support system configured to deliver a pressurized flow of breathable gas to the airway of a subject. The pressure support system is configured to treat COPD and/or other patients suffering from dyspnea and/or other conditions. The pressure support system is configured to be small and lightweight so that a subject may carry the system and use the system as needed without requiring a device to be worn on the face. The present disclosure contemplates that the portable handheld pressure support system may be used to treat symptoms and/or conditions related to dyspnea, and/or for other uses. In one embodiment, the system comprises one or more of a pressure generator, a subject interface, one or more sensors, one or more processors, a user interface, electronic storage, a portable power source, a housing, a handle, and/or other components.

Abstract: The disclosure pertains to determining a melatonin level in a biological sample of a subject with a determination system. The determination system comprises a melatonin analyzer, a temperature sensor, and a controller. The method comprises providing a first biological sample from the subject to the melatonin analyzer; generating one or more output signals conveying information related to a temperature of the analyzer; controlling the temperature of the analyzer based on the output signals to be within a pre-determined temperature range, such that responsive to the temperature of the analyzer being outside the pre-determined temperature range, the controlling comprises cooling and/or heating the analyzer to bring and maintain the temperature within the pre-determined temperature range; and responsive to the temperature of the analyzer being within the pre-determined temperature range, facilitating determination of a melatonin level of the first biological sample with the analyzer.

Abstract: Disclosed is a method for determining onset of a sleep-related analyte. The method includes: obtaining first surrogate measurement(s) of a sleep-related analyte based on signal(s) obtained via sensor(s) during a first time period of observation; obtaining second surrogate measurement(s) of the sleep-related analyte based on signal(s) obtained via sensor(s) during a second time period of observation; determining a first surrogate function or value based on the first surrogate measurement(s) and a second surrogate function or value based on the second surrogate measurement(s); and predicting an onset of the sleep-related analyte for a first individual based on the first surrogate function or value and the second surrogate function or value such that the prediction of the onset of the sleep-related analyte is performed without determining an absolute concentration value for the sleep-related analyte.

Abstract: The present disclosure pertains to a pillow system (40), in particular a pillow system that surrounds the subject's head. In some embodiments, the pillow system provides sound suppression. In some embodiments used with positive airways pressure (“PAP”) systems, the pillow system includes a tube that delivers breathable gas to a mask.

Abstract: The present disclosure pertains to a pillow system, in particular a pillow system that surrounds the subject's head, and moves with the subject. In some embodiments, the pillow system provides sound suppression. In some embodiments used with positive airways pressure (“PAP”) systems, the pillow system includes a tube that delivers breathable gas to a mask.

Abstract: An oxygen liquefier system may be configured to defrost an oxygen line included therein. The system may include one or more sieve beds, a liquid oxygen reservoir, an oxygen line, a controller, a heating apparatus, and/or other components. The one or more sieve beds are configured to extract oxygen from air obtained from an ambient environment. The liquid oxygen reservoir is configured to store oxygen extracted at the one or more sieve beds that has been liquefied. The oxygen line is configured to provide fluid communication between the one or more sieve beds and the liquid oxygen reservoir. The controller is configured to detect a blockage caused by frozen liquid within the oxygen line based on a liquid oxygen production rate. The heating apparatus is configured to defrost the oxygen line to melt frozen liquid within the oxygen line responsive to the detection of the blockage.

Abstract: A Dewar system is configured to liquefy a flow of fluid, and to store the liquefied fluid. The Dewar system is disposed within a single, portable housing. Disposing the components of the Dewar system within the single housing enables liquefied fluid to be transferred between a heat exchange assembly configured to liquefy fluid and a storage assembly configured to store liquefied fluid in an enhanced manner. In one embodiment, the flow of fluid liquefied and stored by the Dewar system is oxygen (e.g., purified oxygen), nitrogen, and/or some other fluid.

Abstract: A fluid is liquefied from a gaseous state to a liquid state, and the liquefied fluid is stored. In one embodiment, the fluid is oxygen. Mechanisms are employed that enhance the durability, longevity, reliability, efficiency, of a system used to liquefy the fluid.

Abstract: A fluid is liquefied from a gaseous state to a liquid state, and the liquefied fluid is stored. In one embodiment, the fluid is oxygen. Mechanisms are employed that enhance the durability, longevity, reliability, efficiency, of a system used to liquefy the fluid.

Abstract: A Dewar system is configured to liquefy a flow of fluid, and to store the liquefied fluid. The Dewar system is disposed within a single, portable housing. Disposing the components of the Dewar system within the single housing enables liquefied fluid to be transferred between a heat exchange assembly configured to liquefy fluid and a storage assembly configured to store liquefied fluid in an enhanced manner. In one embodiment, the flow of fluid liquefied and stored by the Dewar system is oxygen (e.g., purified oxygen), nitrogen, and/or some other fluid.

Abstract: The present disclosure pertains to a pillow system (40), in particular a pillow system that surrounds the subject's head. In some embodiments, the pillow system provides sound suppression. In some embodiments used with positive airways pressure (“PAP”) systems, the pillow system includes a tube that delivers breathable gas to a mask.

Abstract: The present disclosure pertains to a pillow system, in particular a pillow system that surrounds the subject's head, and moves with the subject. In some embodiments, the pillow system provides sound suppression. In some embodiments used with positive airways pressure (“PAP”) systems, the pillow system includes a tube that delivers breathable gas to a mask.

Abstract: The present disclosure pertains to a portable handheld pressure support system configured to deliver a blending gas enriched pressurized flow of breathable gas to the airway of a subject. The pressure support system is configured to treat patients suffering from dyspnea and/or other conditions. The therapy provided to dyspnea patients is configured to be used as needed by a subject to rapidly alleviate shortness of breath. The pressure support system is configured to be small and lightweight so that the subject may carry the system and use the system as needed without requiring a device to be worn on the face. In some embodiments, the system comprises one or more of a pressure generator, a subject interface, a blending gas inlet port, one or more sensors, a valve, one or more processors, a user interface, electronic storage, a portable power source, a housing, a handle, and/or other components.

Abstract: The present disclosure pertains to a portable handheld pressure support system configured to deliver a pressurized flow of breathable gas to the airway of a subject. The pressure support system is configured to treat COPD and/or other patients suffering from dyspnea and/or other conditions. The pressure support system is configured to be small and lightweight so that a subject may carry the system and use the system as needed without requiring a device to be worn on the face. The present disclosure contemplates that the portable handheld pressure support system may be used to treat symptoms and/or conditions related to dyspnea, and/or for other uses. In one embodiment, the system comprises one or more of a pressure generator, a subject interface, one or more sensors, one or more processors, a user interface, electronic storage, a portable power source, a housing, a handle, and/or other components.

Abstract: An oxygen liquefier system may be configured to defrost an oxygen line included therein. The system may include one or more sieve beds, a liquid oxygen reservoir, an oxygen line, a controller, a heating apparatus, and/or other components. The one or more sieve beds are configured to extract oxygen from air obtained from an ambient environment. The liquid oxygen reservoir is configured to store oxygen extracted at the one or more sieve beds that has been liquefied. The oxygen line is configured to provide fluid communication between the one or more sieve beds and the liquid oxygen reservoir. The controller is configured to detect a blockage caused by frozen liquid within the oxygen line based on a liquid oxygen production rate. The heating apparatus is configured to defrost the oxygen line to melt frozen liquid within the oxygen line responsive to the detection of the blockage.

Abstract: A fluid is liquefied from a gaseous state to a liquid state, and the liquefied fluid is stored. In one embodiment, the fluid is oxygen. Mechanisms are employed that enhance the durability, longevity, reliability, efficiency, of a system used to liquefy the fluid.

Abstract: A Dewar system is configured to liquefy a flow of fluid, and to store the liquefied fluid. The Dewar system is disposed within a single, portable housing. Disposing the components of the Dewar system within the single housing enables liquefied fluid to be transferred between a heat exchange assembly configured to liquefy fluid and a storage assembly configured to store liquefied fluid in an enhanced manner. In one embodiment, the flow of fluid liquefied and stored by the Dewar system is oxygen (e.g., purified oxygen), nitrogen, and/or some other fluid.

Abstract: A fluid is liquefied from a gaseous state to a liquid state, and the liquefied fluid is stored. In one embodiment, the fluid is oxygen. Mechanisms are employed that enhance the durability, longevity, reliability, efficiency, of a system used to liquefy the fluid.

Abstract: A fluid is liquefied from a gaseous state to a liquid state, and the liquefied fluid is stored. In one embodiment, the fluid is oxygen. Mechanisms are employed that enhance the durability, longevity, reliability, efficiency, of a system used to liquefy the fluid.

Abstract: A fluid is liquefied from a gaseous state to a liquid state, and the liquefied fluid is stored. In one embodiment, the fluid is oxygen. Mechanisms are employed that enhance the durability, longevity, reliability, efficiency, of a system used to liquefy the fluid.