Patents by Inventor Laurie Brewer

Laurie Brewer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Secreted protein HCEJQ69
    Publication number: 20030044851
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: December 12, 2001
    Publication date: March 6, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Ying-Fei Wei, Paul E. Young, Kimberly A. Florence, Daniel R. Soppet, Laurie A. Brewer, Gregory A. Endress, Kenneth C. Carter, Michael Mucenski, Reinhard Ebner, David W. LaFleur, Henrik S. Olsen, Yanggu Shi, Paul A. Moore, George A. Komatsoulis
  • Secreted protein HT5GJ57
    Publication number: 20030040088
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: October 29, 2001
    Publication date: February 27, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, George Komatsoulis, Roxanne D. Duan, Craig A. Rosen, Paul A. Moore, Yanggu Shi, David W. LaFleur, Reinhard Ebner, Henrik S. Olsen, Laurie A. Brewer, Kimberly A. Florence, Paul E. Young, Michael Mucenski, Gregory A. Endress, Daniel R. Soppet
  • Precerebellin-like protein
    Patent number: 6525174
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: February 25, 2003
    Assignee: Human Genome Sciences, Inc.
    Inventors: Paul Young, John M. Greene, Ann M. Ferrie, Steven M. Ruben, Craig A. Rosen, Jing-Shan Hu, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer, Paul A. Moore, Yanggu Shi, Charles Florence, Kimberly Florence, David W. Lafleur, Jian Ni, Ping Fan, Ying-Fei Wei, Carrie L. Fischer, Daniel R. Soppet, Yi Li, Zhizhen Zeng, Hla Kyaw, Guo-Liang Yu, Ping Feng, Patrick J. Dillon, Gregory A. Endress, Kenneth C. Carter
  • Secreted Protein HODAZ50
    Publication number: 20030027132
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: September 4, 1998
    Publication date: February 6, 2003
    Inventors: STEVEN M. RUBEN, CRAIG A. ROSEN, CARRIE L. FISCHER, DANIEL R. SOPPET, KENNETH C. CARTER, DANIEL R. BEDNARIK, GREGORY A. ENDRESS, GUO-LIANG YU, JIAN NI, PING FENG, PAUL E. YOUNG, JOHN M. GREENE, ANN M. FERRIE, ROXANNE DUAN, JING-SHAN HU, KIMBERLY A. FLORENCE, HENRIK S. OLSEN, REINHARD EBNER, LAURIE A. BREWER, YANGGU SHI
  • Secreted protein HLHFP03
    Publication number: 20030022185
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: October 25, 2001
    Publication date: January 30, 2003
    Inventors: Carrie L. Fischer, Craig A. Rosen, Daniel R. Soppet, Steven M. Ruben, Hla Kyaw, Yi Li, Zhizhen Zeng, David W. LaFleur, Paul A. Moore, Yanggu Shi, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer
  • Secreted protein HT5GJ57
    Publication number: 20030017500
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: October 29, 2001
    Publication date: January 23, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, George Komatsoulis, Roxanne D. Duan, Craig A. Rosen, Paul A. Moore, Yanggu Shi, David W. LaFleur, Reinhard Ebner, Henrik Olsen, Laurie A. Brewer, Kimberly A. Florence, Paul Young, Michael Mucenski, Gregory A. Endress, Daniel R. Soppet
  • 90 human secreted proteins
    Publication number: 20030003555
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: February 1, 2001
    Publication date: January 2, 2003
    Inventors: Steven M. Ruben, Daniel R. Soppet, Reinhard Ebner, Henrik S. Olsen, Paul E. Young, John M. Greene, Ann M. Ferrie, Guo-Liang Yu, Jian Ni, Craig A. Rosen, Laurie A. Brewer, Fouad Janat
  • Secreted protein HRGDF73
    Publication number: 20020164669
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: October 19, 2001
    Publication date: November 7, 2002
    Inventors: Steven M. Ruben, Craig A. Rosen, Carrie L. Fischer, Daniel R. Soppet, Kenneth C. Carter, Daniel P. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer, Yanggu Shi
  • 94 Human Secreted Proteins
    Patent number: 6475753
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: November 5, 2002
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Ying-Fei Wei, Paul Young, Kimberly Florence, Daniel R. Soppet, Laurie A. Brewer, Gregory A. Endress, Kenneth C. Carter, Michael Mucenski, Reinhard Ebner, David W. Lafleur, Henrik Olsen, Yanggu Shi, Paul A. Moore, George Komatsoulis
  • Secreted protein HNFGF20
    Patent number: 6476195
    Abstract: The present invention relates to novel human secreted protein (HNFGF20). Polypeptides of the invention are duseful in dianosis and treatment of disorders affecting the immune system.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: November 5, 2002
    Assignee: Human Genome Sciences, Inc.
    Inventors: George Komatsoulis, Craig A. Rosen, Steven M. Ruben, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Ying-Fei Wei, Jian Ni, Kimberly A. Florence, Paul Young, Laurie A. Brewer, Daniel R. Soppet, Gregory A. Endress, Reinhard Ebner, Henrik Olsen, Michael Mucenski
  • 186 human secreted proteins
    Patent number: 6420526
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Grant
    Filed: September 8, 1998
    Date of Patent: July 16, 2002
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Carrie L. Fischer, Daniel P. Soppet, Kenneth C. Carter, Daniel R. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer, Paul A. Moore, Yanggu Shi, David W. Lafleur, Yi Li, Zhizhen Zeng, Hla Kyaw
  • Novel Metalloproteinases
    Publication number: 20020042119
    Abstract: The present invention relates to novel metalloproteinase-like proteins. In particular, isolated nucleic acid molecules are provided encoding the human TACE-like and matrilysin-like proteins. TACE-like and matrilysin-like polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TACE-like and matrilysin-like activity. Also provided are diagnostic methods for detecting cancer and therapeutic methods for cancer and other disorders characterized by an over or under production of these metalloproteinases.
    Type: Application
    Filed: September 13, 2001
    Publication date: April 11, 2002
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Steve Ruben, Laurie Brewer, Reiner Gentz, Craig Rosen
  • Metalloproteinases
    Patent number: 6312937
    Abstract: The present invention relates to novel metalloproteinase- like proteins. In particular, isolated nucleic acid molecules are provided encoding the human TACE-like and matrilysin-like proteins. TACE-like and matrilysin-like polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TACE-like and matrilysin-like activity. Also provided are diagnostic methods for detecting cancer and therapeutic methods for cancer and other disorders characterized by an over or under production of these metalloproteinases.
    Type: Grant
    Filed: August 11, 1999
    Date of Patent: November 6, 2001
    Assignee: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Steve Ruben, Laurie Brewer, Reiner Gentz, Craig Rosen
  • 36 human secreted proteins
    Publication number: 20010012889
    Abstract: The present invention relates to 36 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: December 20, 2000
    Publication date: August 9, 2001
    Inventors: David W. LaFleur, Daniel R. Soppet, Henrik Olsen, Steven M. Ruben, Jian Ni, Craig A. Rosen, Laurie A. Brewer, Roxanne Duan, Reinhard Ebner
  • Metalloproteinases
    Patent number: 6046031
    Abstract: The present invention relates to novel metalloproteinase-like proteins. In particular, isolated nucleic acid molecules are provided encoding the human TACE-like and matrilysin-like proteins. TACE-like and matrilysin-like polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TACE-like and matrilysin-like activity. Also provided are diagnostic methods for detecting cancer and therapeutic methods for cancer and other disorders characterized by an over or under production of these metalloproteinases.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: April 4, 2000
    Assignee: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Steve Ruben, Laurie Brewer, Reiner Gentz, Craig Rosen