Abstract: Described herein is a capsule (1000) comprising a front cover (1100) having a front wall (1110) having a front wall top edge (1112), a first side wall (1120) having a first side wall extension (1122), a second side wall (1130) having a second side wall extension (1132), and a bottom wall (1140), where both the first and the second side walls extensions (1122, 1132) extend beyond the front wall top edge (1112) relative to the bottom wall(1140), the capsule (1000) further comprises a back cover (1200) coupled to the front cover (1100) having a back wall (1210) and a top wall (1250), where the back wall (1210) includes a recess hinge (1212), where a portion of the back wall (1210) above the position of the hinge (1212) and the top wall (1250) are configured as a back flap (1214), and where the coupled front and back covers (1100, 1200) define a capsule interior.

Abstract: This disclosure provides a technology for developing alternative protein sources for use in industrial food production. The technology evaluates naturally occurring proteins by a process that is done partly in silico and partly by empirical evaluation. A database is created in which each individual protein is characterized by vector representations of structural and functional features. Clusters of individual proteins are formed by pairwise comparison of each protein's vector representation, adjusting the degree of similarity used to define clusters until a desired number of clusters are obtained. A protein representative is selected from each cluster for evaluation by high-throughput expression and laboratory testing for a particular food function. High scoring representatives identify clusters that can be mined for additional protein candidates. Multiple cycles of the machine learning, database mining, expression and testing yield ingredients suitable for assessment as part of a commercial food product.

Abstract: This disclosure provides a technology for developing individual proteins for use in industrial processes that include food production. The technology mines sequence data from protein databases by a process that is done partly in silico. Instead of sampling and testing a vast library of compounds, machine learning and implementation narrows the field of functional candidates by predictive modeling based on known protein structure. Candidate proteins that are selected by this analysis are then produced and screened in a high-throughput manner by recombinant expression and testing to determine whether they have a target function. Multiple cycles of the machine learning, database mining, expression, and testing are done to yield potential ingredients suitable for use in the production of foods, cosmetics, agricultural feed, pharmaceutical excipients, and other industrial products.

Abstract: A blanket suspender assembly for suspending a blanket around pants of a user includes a blanket and a suspender. A strip is coupled along a full length of a top edge of the blanket. The strip is a first portion of a hook and loop fastener. The suspender comprises of a pair of straps. Each strap of the pair of straps has a front hinge and a back hinge. The suspender is placed on the shoulders of a user where the front fringe of each strap is positioned in front of the user and the back fringe of each strap is positioned behind the user. A plurality of tabs is coupled to a respective one of each front hinge and each back hinge. Each of the tabs is the second portion of the hook and loop fastener. Each of the tabs engages by hook and loop fastening with the strip.

Abstract: A blanket suspender assembly for suspending a blanket around pants of a user includes a blanket and a suspender. A strip is coupled along a full length of a top edge of the blanket. The strip is a first portion of a hook and loop fastener. The suspender comprises of a pair of straps. Each strap of the pair of straps has a front hinge and a back hinge. The suspender is placed on the shoulders of a user where the front fringe of each strap is positioned in front of the user and the back fringe of each strap is positioned behind the user. A plurality of tabs is coupled to a respective one of each front hinge and each back hinge. Each of the tabs is the second portion of the hook and loop fastener. Each of the tabs engages by hook and loop fastening with the strip.

Abstract: This disclosure provides a technology for developing alternative protein sources for use in industrial food production. The technology mines sequence data by a process that is done partly in silico. Instead of sampling and testing a vast library of compounds, machine learning and implementation narrows the field of functional candidates by predictive modeling based on known protein structure. Candidate proteins that are selected by this analysis are then produced and screened in a high-throughput manner by recombinant expression and testing to determine whether they have a target function. Multiple cycles of the machine learning, database mining, expression, and testing are done to yield potential ingredients suitable for assessment as part of a commercial food product.

Abstract: This disclosure provides a technology for developing alternative protein sources for use in industrial food production. The technology mines natural sources by a process that is done partly in silico. Instead of sampling and testing a vast library of compounds, machine learning and implementation narrows the field of functional candidates by predictive modeling based on known protein structure. Candidate proteins that are selected by this analysis are then produced and screened in a high-throughput manner by recombinant expression and testing to determine whether they have a target function. Multiple cycles of the machine learning, database mining, expression and testing are done to yield potential ingredients suitable for assessment as part of a commercial food product.

Abstract: This disclosure provides a technology for developing alternative protein sources for use in industrial food production. The technology mines natural sources by a process that is done partly in silico. Instead of sampling and testing a vast library of compounds, machine learning and implementation narrows the field of functional candidates by predictive modeling based on known protein structure. Candidate proteins that are selected by this analysis are then produced and screened in a high-throughput manner by recombinant expression and testing to determine whether they have a target function. Multiple cycles of the machine learning, database mining, expression and testing are done to yield potential ingredients suitable for assessment as part of a commercial food product.

Abstract: A liquid immersion microscope objective assembly includes an objective, a liquid delivery system for delivering an immersion liquid to a lens of the objective, and a liquid return system for removing liquid from an area around the lens. The objective may be positioned below a sample container. Liquid is delivered to the lens so as to form a bolus between the lens and the sample container. Excess liquid drains into the return system, which may be done via a notch or a V-shaped channel. Additionally, the direction of flow through the delivery system may be reversed, such that liquid may also be removed from the area around the lens via the delivery system. The assembly may also be utilized to remove liquid from the underside of the sample container. The assembly may also include a leak sensor and/or an electrowetting device.

Abstract: A liquid immersion microscope objective assembly includes an objective, a liquid delivery system for delivering an immersion liquid to a lens of the objective, and a liquid return system for removing liquid from an area around the lens. The objective may be positioned below a sample container. Liquid is delivered to the lens so as to form a bolus between the lens and the sample container. Excess liquid drains into the return system, which may be done via a notch or a V-shaped channel. Additionally, the direction of flow through the delivery system may be reversed, such that liquid may also be removed from the area around the lens via the delivery system. The assembly may also be utilized to remove liquid from the underside of the sample container. The assembly may also include a leak sensor and/or an electrowetting device.

Abstract: Techniques involve a motor assembly including a rotor and a stator. The stator includes a contact surface for contacting an outer surface of the rotor. The contact surface includes a rigid material. The motor assembly also includes at least one constraint disposed along a length of the motor assembly, where the constraint constrains a radial and/or tangential movement of the rotor relative to the stator. The at least one constraint may be disposed at one or more proximate ends of the motor assembly, and/or along the length of the motor assembly. The contact surface of the stator may have a profile including peaks and valleys, and in some embodiments, the contact surface may be treated to reduce friction and/or wear.

Abstract: A method and apparatus are disclosed for providing a coat rack, a shoe rack and a tool rack all modified from a staple commodity of construction commerce such as polyvinylchloride piping. Methods for modifying this construction material for a specific use as one of the various types of racks is disclosed along with the tools and techniques necessary for such modifications.

Abstract: A method is described for determining automatically, via a network protocol, a system topology of a network system, wherein the network system comprises a plurality of network components, wherein each of the network components support a directory protocol, and wherein the system topology comprises a respective address of each of the plurality of network components. The system topology is mapped via the directory protocol. Finally, a role-based access credential is configured for a user, via the directory protocol, wherein the role-based access credential determines which of the plurality of network components are accessible to the user.

Abstract: Algorithm-based molecular assays that involve measurement of expression levels of prognostic and/or predictive genes, or co-expressed genes thereof, from a biological sample obtained from a cancer patient, and analysis of the measured expression levels to provide information concerning the likelihood of recurrence of colorectal cancer and/or the likelihood of a beneficial response to chemotherapy for the patient are provided herein. Methods of analysis of gene expression values of prognostic and/or predictive genes, as well as methods of identifying gene expression-tumor region ratios, tumor-associated stromal surface area, and gene cliques, i.e. genes that co-express with a validated biomarker and thus may be substituted for that biomarker in an assay, are also provided.

Abstract: Techniques relate to a moving cavity motor or pump, such as a mud motor, including a rotor, a stator, and one or more apparatus for constraining (i.e., controlling or limiting) the movement of the rotor relative to the stator, where the apparatus for constraining is operable with the rotor catch. The motor may include a top sub, power section having a progressive cavity motor with a stator and rotor, a rotor catch, and an apparatus between a proximal and distal end of the rotor catch shaft. The apparatus may constrain the radial and/or tangential movement of the rotor catch shaft and the rotor.

Abstract: An apparatus for automatically conditioning a patch plate and a plenum of an electrophysiology measurement system is provided. An arm is linearly movable between a non-operative position and an operative position. An end effector mounted to one side of the arm is configured to condition the patch plate. Another end effector mounted to an opposite side of the arm is configured to condition the plenum. A linear actuator is coupled to the arm and is configured to drive movement of the arm between the operative position and the non-operative position. When the arm is positioned in the operative position, the arm is situated between the patch plate and the plenum.