Patents by Inventor Lawrence Williams
Lawrence Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11532377Abstract: Systems and methods for modeling a three-dimensional protein structure are disclosed. The method includes receiving a primary amino acid sequence of a three-dimensional protein, translating the primary amino acid sequence to a first vector, determining a per-residue conformation index for each amino acid residue in the primary amino acid sequence, determining a vector set for each amino acid residue in the primary amino acid sequence, and using the per-residue interaction vector set to generate a multi-dimensional matrix for the three-dimensional protein structure. The first vector includes a unique numerical descriptor value corresponding to each amino acid residue in the primary amino acid sequence. The vector set includes a plurality per-residue interaction factors corresponding to a plurality of conformation indexes for that amino acid residue.Type: GrantFiled: March 23, 2018Date of Patent: December 20, 2022Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEYInventors: Lawrence Williams, Brian Schendt
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Patent number: 11354107Abstract: Some examples provide a non-transitory computer readable medium having instructions stored thereon and executable by a processor of a client computing device to receive, from a server computing device, a unique identifier associated with the client computing device. The instructions are executable by the processor to receive, at the client computing device, user input including a password associated with the unique identifier. The instructions are executable by the processor to send the password to the server computing device for verification. The instructions are executable by the processor to receive, from the server computing device, a data image for installing a desired operating system on the client computing device, and doing so according to a user selection received at the client computing device.Type: GrantFiled: January 16, 2015Date of Patent: June 7, 2022Assignee: Hewlett-Packard Development Company, L.P.Inventors: Yuan-Yang Huang, Lawrence Williams, Tian-Yan Huang
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Publication number: 20200286581Abstract: Systems and methods for modeling a three-dimensional protein structure are disclosed. The method includes receiving a primary amino acid sequence of a three-dimensional protein, translating the primary amino acid sequence to a first vector, determining a per-residue conformation index for each amino acid residue in the primary amino acid sequence, determining a vector set for each amino acid residue in the primary amino acid sequence, and using the per-residue interaction vector set to generate a multi-dimensional matrix for the three-dimensional protein structure. The first vector includes a unique numerical descriptor value corresponding to each amino acid residue in the primary amino acid sequence. The vector set includes a plurality per-residue interaction factors corresponding to a plurality of conformation indexes for that amino acid residue.Type: ApplicationFiled: March 23, 2018Publication date: September 10, 2020Inventors: Lawrence Williams, Brian Schendt
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Patent number: 10761906Abstract: Examples relate to multi-device collaboration. The examples disclosed herein enable identifying, by a first computing device having a first processor, a first role to be played by the first computing device when the first computing device is connected with a second computing device having a second processor. The second computing device may play a second role when the second computing device is connected with the first computing device. The examples further enable determining, by the first computing device, when at least one predetermined triggering event occurs that causes the first role and second role to be switched such that the first role is played by the second computing device and the second role is played by the first computing device.Type: GrantFiled: August 29, 2014Date of Patent: September 1, 2020Assignee: Hewlett-Packard Development Company, L.P.Inventors: Eric Michael Lunsford, Donald Gonzalez, Lawrence Williams, Yuan-Yang Huang, Tian-Yan Huang
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Patent number: 10379878Abstract: Some examples provide a method where based on physical identifier data relating to a set of physical identifiers associated with a customer-ordered computer system, purchase order data associated with the customer-ordered computer system is generated. The purchase order data describes a set of software items to be installed on the customer-ordered computer system. The purchase order data is stored on a datastore in association with a hardware identifier associated with the customer-ordered computer system. Subsequently, a software tool is sent to the customer-ordered computer system, where the software tool is configured to cause the customer-ordered computer system to obtain the purchase order data from the datastore based on the hardware identifier, and download the set of software items based on the purchase order data obtained from the datastore.Type: GrantFiled: January 23, 2015Date of Patent: August 13, 2019Assignee: Hewlett-Packard Development Company, L.P.Inventor: Lawrence Williams
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Patent number: 10265110Abstract: A self-locking screw with a raised root is provided. The self-locking screw has a head, a distal end, and a shaft extending between the head and the distal end. The shaft includes a thread with a plurality of turns so as to define a root, the raised root extending over the root for at least a subset of the plurality of turns proximal to the head. The raised root is removably attached to the root and detaches from the root when the self-locking screw is screwed into a substrate such that the detached raised root binds between the self-locking screw and the substrate and/or becomes embedded within the substrate.Type: GrantFiled: October 19, 2016Date of Patent: April 23, 2019Assignee: Alphatec Spine, Inc.Inventor: Lawrence Williams
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Publication number: 20170344389Abstract: Some examples provide a method where based on physical identifier data relating to a set of physical identifiers associated with a customer-ordered computer system, purchase order data associated with the customer-ordered computer system is generated. The purchase order data describes a set of software items to be installed on the customer-ordered computer system. The purchase order data is stored on a datastore in association with a hardware identifier associated with the customer-ordered computer system. Subsequently, a software tool is sent to the customer-ordered computer system, where the software tool is configured to cause the customer-ordered computer system to obtain the purchase order data from the datastore based on the hardware identifier, and download the set of software items based on the purchase order data obtained from the datastore.Type: ApplicationFiled: January 23, 2015Publication date: November 30, 2017Applicant: Hewlett-Packard Development Company, L.P.Inventor: Lawrence Williams
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Publication number: 20170329594Abstract: Some examples provide a non-transitory computer readable medium having instructions stored thereon and executable by a processor of a client computing device to receive, from a server computing device, a unique identifier associated with the client computing device. The instructions are executable by the processor to receive, at the client computing device, user input including a password associated with the unique identifier. The instructions are executable by the processor to send the password to the server computing device for verification. The instructions are executable by the processor to receive, from the server computing device, a data image for installing a desired operating system on the client computing device, and doing so according to a user selection received at the client computing device.Type: ApplicationFiled: January 16, 2015Publication date: November 16, 2017Applicant: Hewlett-Packard Development Company, L.P.Inventors: Yuan-Yang Huang, Lawrence Williams, Tian-Yan Huang
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Publication number: 20170293506Abstract: Examples relate to multi-device collaboration. The examples disclosed herein enable identifying, by a first computing device having a first processor, a first role to be played by the first computing device when the first computing device is connected with a second computing device having a second processor. The second computing device may play a second role when the second computing device is connected with the first computing device. The examples further enable determining, by the first computing device, when at least one predetermined triggering event occurs that causes the first role and second role to be switched such that the first role is played by the second computing device and the second role is played by the first computing device.Type: ApplicationFiled: August 29, 2014Publication date: October 12, 2017Inventors: Eric Michael Lunsford, Donald Gonzalez, Lawrence Williams, Yuan-Yang Huang, Tian-Yan Huang
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Publication number: 20170105778Abstract: A self-locking screw with a raised root is provided. The self-locking screw has a head, a distal end, and a shaft extending between the head and the distal end. The shaft includes a thread with a plurality of turns so as to define a root, the raised root extending over the root for at least a subset of the plurality of turns proximal to the head. The raised root is removably attached to the root and detaches from the root when the self-locking screw is screwed into a substrate such that the detached raised root binds between the self-locking screw and the substrate and/or becomes embedded within the substrate.Type: ApplicationFiled: October 19, 2016Publication date: April 20, 2017Inventor: Lawrence Williams
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Patent number: 9557132Abstract: A device for removing grease from a tubular drain includes a central member. The device also includes an overmolded structure having a plurality of overmolded wiping discs and a plurality of overmolded support structures. Each wiping disc is supported by an overmolded support on either side of each wiping disc of the plurality of wiping discs. At least one of the plurality of overmolded support structures has at least one hole configured to accept a pin to non-slidingly affix the overmolded structure to the central member. Methods for using the device and for manufacturing the device are also described.Type: GrantFiled: January 7, 2014Date of Patent: January 31, 2017Assignee: Otis Products, Inc.Inventors: Nicholas Williams, Lawrence Williams
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Patent number: 9464116Abstract: The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.Type: GrantFiled: January 6, 2014Date of Patent: October 11, 2016Assignee: Sloan-Kettering Institute for Cancer ResearchInventors: Samuel J. Danishefsky, Jennifer R. Allen, Govindaswami Ragupathi, Philip O. Livingston, Lawrence Williams
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Patent number: 9204896Abstract: An instrument for removing material from within the body includes a distal portion that includes an adjustable length relative to a proximal portion and a flexible member that circulates through the distal portion. The exposed portion of the flexible member extends from the distal portion to remove the material.Type: GrantFiled: July 10, 2012Date of Patent: December 8, 2015Assignee: ALPHATEC SPINE, INC.Inventor: Lawrence Williams
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Publication number: 20140271817Abstract: The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.Type: ApplicationFiled: January 6, 2014Publication date: September 18, 2014Applicant: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCHInventors: Samuel J. Danishefsky, Jennifer R. Allen, Govindaswami Ragupathi, Philip O. Livingston, Lawrence Williams
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Patent number: 8800191Abstract: A firearm barrel cleaning brush includes a body, a first swab portion affixed to the body, a bristle brush portion affixed to the body, and a second swab portion affixed to the body. The bristle brush portion is proximate to the first swab portion, and is positioned closer to an end of the body than the first swab portion. The second swab portion is proximate to the bristle brush portion, and is positioned closer to the end of the body than the bristle brush portion. In one embodiment, the cleaning brush is secured to a flexible cleaning rod having a pull-through handle having a base, a swivel, and a handle portion attached to the base by the swivel. The handle portion has a closed position adapted for passage through the firearm barrel, and an open position adapted for pulling the cleaning rod and barrel cleaning brush through the firearm barrel.Type: GrantFiled: January 17, 2012Date of Patent: August 12, 2014Assignee: The Otis Patent TrustInventors: Lawrence Williams, Kel Shipman
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Patent number: 8623378Abstract: The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.Type: GrantFiled: January 31, 2011Date of Patent: January 7, 2014Assignee: Sloan-Kettering Institute for Cancer ResearchInventors: Samuel J. Danishefsky, Jennifer R. Allen, Govindaswami Ragupathi, Philip O. Livingston, Lawrence Williams
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Publication number: 20130018377Abstract: An instrument for removing material from within the body includes a distal portion that includes an adjustable length relative to a proximal portion and a flexible member that circulates through the distal portion. The exposed portion of the flexible member extends from the distal portion to remove the material.Type: ApplicationFiled: July 10, 2012Publication date: January 17, 2013Applicant: Alphatec Spine, Inc.Inventor: Lawrence WILLIAMS
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Publication number: 20120186128Abstract: A firearm barrel cleaning brush includes a body, a first swab portion affixed to the body, a bristle brush portion affixed to the body, and a second swab portion affixed to the body. The bristle brush portion is proximate to the first swab portion, and is positioned closer to an end of the body than the first swab portion. The second swab portion is proximate to the bristle brush portion, and is positioned closer to the end of the body than the bristle brush portion. In one embodiment, the cleaning brush is secured to a flexible cleaning rod having a pull-through handle having a base, a swivel, and a handle portion attached to the base by the swivel. The handle portion has a closed position adapted for passage through the firearm barrel, and an open position adapted for pulling the cleaning rod and barrel cleaning brush through the firearm barrel.Type: ApplicationFiled: January 17, 2012Publication date: July 26, 2012Applicant: The Otis Patent TrustInventors: Lawrence Williams, Kel Shipman
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Patent number: 8186092Abstract: A firearm cleaning kit is disclosed that includes a case having first and second compartments joined along a fold line, and a fastener, such as a zipper, joining together the first and second compartments of the case. At least one of the compartments includes a pocket. A flexible cleaning rod having a first end and a second end is removably stored in the pocket. A tool compartment is secured to the fold line. The tool compartment includes a plurality of tool-holding cavities, and a firearm barrel cleaning device is secured within one of the tool-holding cavities. The barrel cleaning device includes a body portion, a swab, and a brush. The swab is fixed to a first end of the body portion, and has an outer diameter greater than an inner diameter of the firearm barrel so as to contact the barrel at all points around its circumference.Type: GrantFiled: September 1, 2009Date of Patent: May 29, 2012Assignee: The Otis Patent TrustInventor: Lawrence Williams
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Publication number: 20110206757Abstract: The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.Type: ApplicationFiled: January 31, 2011Publication date: August 25, 2011Applicant: Sloan Kettering Institute for Cancer ResearchInventors: Samuel J. Danishefsky, Jennifer R. Allen, Govindaswami Ragupathi, Philip O. Livingston, Lawrence Williams