Patents by Inventor Lawrence Williams

Lawrence Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11532377
    Abstract: Systems and methods for modeling a three-dimensional protein structure are disclosed. The method includes receiving a primary amino acid sequence of a three-dimensional protein, translating the primary amino acid sequence to a first vector, determining a per-residue conformation index for each amino acid residue in the primary amino acid sequence, determining a vector set for each amino acid residue in the primary amino acid sequence, and using the per-residue interaction vector set to generate a multi-dimensional matrix for the three-dimensional protein structure. The first vector includes a unique numerical descriptor value corresponding to each amino acid residue in the primary amino acid sequence. The vector set includes a plurality per-residue interaction factors corresponding to a plurality of conformation indexes for that amino acid residue.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: December 20, 2022
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Lawrence Williams, Brian Schendt
  • Patent number: 11354107
    Abstract: Some examples provide a non-transitory computer readable medium having instructions stored thereon and executable by a processor of a client computing device to receive, from a server computing device, a unique identifier associated with the client computing device. The instructions are executable by the processor to receive, at the client computing device, user input including a password associated with the unique identifier. The instructions are executable by the processor to send the password to the server computing device for verification. The instructions are executable by the processor to receive, from the server computing device, a data image for installing a desired operating system on the client computing device, and doing so according to a user selection received at the client computing device.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: June 7, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Yuan-Yang Huang, Lawrence Williams, Tian-Yan Huang
  • Publication number: 20200286581
    Abstract: Systems and methods for modeling a three-dimensional protein structure are disclosed. The method includes receiving a primary amino acid sequence of a three-dimensional protein, translating the primary amino acid sequence to a first vector, determining a per-residue conformation index for each amino acid residue in the primary amino acid sequence, determining a vector set for each amino acid residue in the primary amino acid sequence, and using the per-residue interaction vector set to generate a multi-dimensional matrix for the three-dimensional protein structure. The first vector includes a unique numerical descriptor value corresponding to each amino acid residue in the primary amino acid sequence. The vector set includes a plurality per-residue interaction factors corresponding to a plurality of conformation indexes for that amino acid residue.
    Type: Application
    Filed: March 23, 2018
    Publication date: September 10, 2020
    Inventors: Lawrence Williams, Brian Schendt
  • Patent number: 10761906
    Abstract: Examples relate to multi-device collaboration. The examples disclosed herein enable identifying, by a first computing device having a first processor, a first role to be played by the first computing device when the first computing device is connected with a second computing device having a second processor. The second computing device may play a second role when the second computing device is connected with the first computing device. The examples further enable determining, by the first computing device, when at least one predetermined triggering event occurs that causes the first role and second role to be switched such that the first role is played by the second computing device and the second role is played by the first computing device.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: September 1, 2020
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Eric Michael Lunsford, Donald Gonzalez, Lawrence Williams, Yuan-Yang Huang, Tian-Yan Huang
  • Patent number: 10379878
    Abstract: Some examples provide a method where based on physical identifier data relating to a set of physical identifiers associated with a customer-ordered computer system, purchase order data associated with the customer-ordered computer system is generated. The purchase order data describes a set of software items to be installed on the customer-ordered computer system. The purchase order data is stored on a datastore in association with a hardware identifier associated with the customer-ordered computer system. Subsequently, a software tool is sent to the customer-ordered computer system, where the software tool is configured to cause the customer-ordered computer system to obtain the purchase order data from the datastore based on the hardware identifier, and download the set of software items based on the purchase order data obtained from the datastore.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: August 13, 2019
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventor: Lawrence Williams
  • Patent number: 10265110
    Abstract: A self-locking screw with a raised root is provided. The self-locking screw has a head, a distal end, and a shaft extending between the head and the distal end. The shaft includes a thread with a plurality of turns so as to define a root, the raised root extending over the root for at least a subset of the plurality of turns proximal to the head. The raised root is removably attached to the root and detaches from the root when the self-locking screw is screwed into a substrate such that the detached raised root binds between the self-locking screw and the substrate and/or becomes embedded within the substrate.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: April 23, 2019
    Assignee: Alphatec Spine, Inc.
    Inventor: Lawrence Williams
  • Publication number: 20170344389
    Abstract: Some examples provide a method where based on physical identifier data relating to a set of physical identifiers associated with a customer-ordered computer system, purchase order data associated with the customer-ordered computer system is generated. The purchase order data describes a set of software items to be installed on the customer-ordered computer system. The purchase order data is stored on a datastore in association with a hardware identifier associated with the customer-ordered computer system. Subsequently, a software tool is sent to the customer-ordered computer system, where the software tool is configured to cause the customer-ordered computer system to obtain the purchase order data from the datastore based on the hardware identifier, and download the set of software items based on the purchase order data obtained from the datastore.
    Type: Application
    Filed: January 23, 2015
    Publication date: November 30, 2017
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventor: Lawrence Williams
  • Publication number: 20170329594
    Abstract: Some examples provide a non-transitory computer readable medium having instructions stored thereon and executable by a processor of a client computing device to receive, from a server computing device, a unique identifier associated with the client computing device. The instructions are executable by the processor to receive, at the client computing device, user input including a password associated with the unique identifier. The instructions are executable by the processor to send the password to the server computing device for verification. The instructions are executable by the processor to receive, from the server computing device, a data image for installing a desired operating system on the client computing device, and doing so according to a user selection received at the client computing device.
    Type: Application
    Filed: January 16, 2015
    Publication date: November 16, 2017
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Yuan-Yang Huang, Lawrence Williams, Tian-Yan Huang
  • Publication number: 20170293506
    Abstract: Examples relate to multi-device collaboration. The examples disclosed herein enable identifying, by a first computing device having a first processor, a first role to be played by the first computing device when the first computing device is connected with a second computing device having a second processor. The second computing device may play a second role when the second computing device is connected with the first computing device. The examples further enable determining, by the first computing device, when at least one predetermined triggering event occurs that causes the first role and second role to be switched such that the first role is played by the second computing device and the second role is played by the first computing device.
    Type: Application
    Filed: August 29, 2014
    Publication date: October 12, 2017
    Inventors: Eric Michael Lunsford, Donald Gonzalez, Lawrence Williams, Yuan-Yang Huang, Tian-Yan Huang
  • Publication number: 20170105778
    Abstract: A self-locking screw with a raised root is provided. The self-locking screw has a head, a distal end, and a shaft extending between the head and the distal end. The shaft includes a thread with a plurality of turns so as to define a root, the raised root extending over the root for at least a subset of the plurality of turns proximal to the head. The raised root is removably attached to the root and detaches from the root when the self-locking screw is screwed into a substrate such that the detached raised root binds between the self-locking screw and the substrate and/or becomes embedded within the substrate.
    Type: Application
    Filed: October 19, 2016
    Publication date: April 20, 2017
    Inventor: Lawrence Williams
  • Patent number: 9557132
    Abstract: A device for removing grease from a tubular drain includes a central member. The device also includes an overmolded structure having a plurality of overmolded wiping discs and a plurality of overmolded support structures. Each wiping disc is supported by an overmolded support on either side of each wiping disc of the plurality of wiping discs. At least one of the plurality of overmolded support structures has at least one hole configured to accept a pin to non-slidingly affix the overmolded structure to the central member. Methods for using the device and for manufacturing the device are also described.
    Type: Grant
    Filed: January 7, 2014
    Date of Patent: January 31, 2017
    Assignee: Otis Products, Inc.
    Inventors: Nicholas Williams, Lawrence Williams
  • Patent number: 9464116
    Abstract: The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.
    Type: Grant
    Filed: January 6, 2014
    Date of Patent: October 11, 2016
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Samuel J. Danishefsky, Jennifer R. Allen, Govindaswami Ragupathi, Philip O. Livingston, Lawrence Williams
  • Patent number: 9204896
    Abstract: An instrument for removing material from within the body includes a distal portion that includes an adjustable length relative to a proximal portion and a flexible member that circulates through the distal portion. The exposed portion of the flexible member extends from the distal portion to remove the material.
    Type: Grant
    Filed: July 10, 2012
    Date of Patent: December 8, 2015
    Assignee: ALPHATEC SPINE, INC.
    Inventor: Lawrence Williams
  • Publication number: 20140271817
    Abstract: The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.
    Type: Application
    Filed: January 6, 2014
    Publication date: September 18, 2014
    Applicant: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
    Inventors: Samuel J. Danishefsky, Jennifer R. Allen, Govindaswami Ragupathi, Philip O. Livingston, Lawrence Williams
  • Patent number: 8800191
    Abstract: A firearm barrel cleaning brush includes a body, a first swab portion affixed to the body, a bristle brush portion affixed to the body, and a second swab portion affixed to the body. The bristle brush portion is proximate to the first swab portion, and is positioned closer to an end of the body than the first swab portion. The second swab portion is proximate to the bristle brush portion, and is positioned closer to the end of the body than the bristle brush portion. In one embodiment, the cleaning brush is secured to a flexible cleaning rod having a pull-through handle having a base, a swivel, and a handle portion attached to the base by the swivel. The handle portion has a closed position adapted for passage through the firearm barrel, and an open position adapted for pulling the cleaning rod and barrel cleaning brush through the firearm barrel.
    Type: Grant
    Filed: January 17, 2012
    Date of Patent: August 12, 2014
    Assignee: The Otis Patent Trust
    Inventors: Lawrence Williams, Kel Shipman
  • Patent number: 8623378
    Abstract: The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: January 7, 2014
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Samuel J. Danishefsky, Jennifer R. Allen, Govindaswami Ragupathi, Philip O. Livingston, Lawrence Williams
  • Publication number: 20130018377
    Abstract: An instrument for removing material from within the body includes a distal portion that includes an adjustable length relative to a proximal portion and a flexible member that circulates through the distal portion. The exposed portion of the flexible member extends from the distal portion to remove the material.
    Type: Application
    Filed: July 10, 2012
    Publication date: January 17, 2013
    Applicant: Alphatec Spine, Inc.
    Inventor: Lawrence WILLIAMS
  • Publication number: 20120186128
    Abstract: A firearm barrel cleaning brush includes a body, a first swab portion affixed to the body, a bristle brush portion affixed to the body, and a second swab portion affixed to the body. The bristle brush portion is proximate to the first swab portion, and is positioned closer to an end of the body than the first swab portion. The second swab portion is proximate to the bristle brush portion, and is positioned closer to the end of the body than the bristle brush portion. In one embodiment, the cleaning brush is secured to a flexible cleaning rod having a pull-through handle having a base, a swivel, and a handle portion attached to the base by the swivel. The handle portion has a closed position adapted for passage through the firearm barrel, and an open position adapted for pulling the cleaning rod and barrel cleaning brush through the firearm barrel.
    Type: Application
    Filed: January 17, 2012
    Publication date: July 26, 2012
    Applicant: The Otis Patent Trust
    Inventors: Lawrence Williams, Kel Shipman
  • Patent number: 8186092
    Abstract: A firearm cleaning kit is disclosed that includes a case having first and second compartments joined along a fold line, and a fastener, such as a zipper, joining together the first and second compartments of the case. At least one of the compartments includes a pocket. A flexible cleaning rod having a first end and a second end is removably stored in the pocket. A tool compartment is secured to the fold line. The tool compartment includes a plurality of tool-holding cavities, and a firearm barrel cleaning device is secured within one of the tool-holding cavities. The barrel cleaning device includes a body portion, a swab, and a brush. The swab is fixed to a first end of the body portion, and has an outer diameter greater than an inner diameter of the firearm barrel so as to contact the barrel at all points around its circumference.
    Type: Grant
    Filed: September 1, 2009
    Date of Patent: May 29, 2012
    Assignee: The Otis Patent Trust
    Inventor: Lawrence Williams
  • Publication number: 20110206757
    Abstract: The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.
    Type: Application
    Filed: January 31, 2011
    Publication date: August 25, 2011
    Applicant: Sloan Kettering Institute for Cancer Research
    Inventors: Samuel J. Danishefsky, Jennifer R. Allen, Govindaswami Ragupathi, Philip O. Livingston, Lawrence Williams