Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.

Abstract: Methods of forming microelectronic structures using multilayer processes are disclosed. The methods comprise the use of a developer-soluble protective layer adjacent the substrate surface in a multilayer stack to protect the substrate during pattern transfer. After etching, the pattern is transferred into the developer-soluble protective layer using a developer instead of etching required by previous methods. Conventional developer-soluble anti-reflective coatings and gap-fill materials can be used to form the protective layer. Custom layers with developer solubility can also be prepared. Microelectronic structures formed by the above processes are also disclosed.

Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4, and R5 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).

Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).

Abstract: Exemplary embodiments are directed to systems, devices, methods, and computer-readable media for reducing static and dynamic power consumption of a charge pump. In one embodiment, a device may include a plurality of switches, each switch of the plurality having a gate coupled to a dedicated driver of a plurality of drivers. The device may further include at least one clamp switch coupled to at least one driver of the plurality of drivers and configured to adjust a rail voltage of the at least one driver if an input voltage is greater than a threshold voltage. In another embodiment, the device may include a plurality of multiplexers, each multiplexer of the plurality of multiplexers coupled to a portion of an associated switch of the plurality of switches and configured to disable the portion of the associated switch if a clock frequency of the charge pump is below a threshold frequency.

Abstract: A Metal-Oxide-Semiconductor Field Effect Transistor (MOSFET) is disclosed. The MOSFET includes a substrate, a well region formed in the substrate, a shallow channel layer, a channel, a gate oxide layer, a gate region, a source region, and a drain region. The shallow channel layer is formed on a portion of the well region and includes a first shallow channel region and a second shallow channel region. The channel is arranged between the first shallow channel region and the second shallow channel region and connects the first shallow channel region and the second shallow channel region. Further, the gate oxide layer is formed on a portion of the well region between the first shallow channel region and the second shallow channel region and includes a first gate oxide region and a second gate oxide region arranged on different sides of the channel.

Abstract: Embodiments of the present invention provide a web page color setting method, a web browser, and a web server. The web page color setting method is used to set a color of a web page, where the web page includes a web page background and a content background, and a color of the web page background is different from a color of the content background. With the technical solutions provided in the embodiments of the present invention, setting the web page color will not influence the color of other contents displayed by the monitor. Moreover, the process of setting the web page color is quite simple, and easy to implement. Therefore, the technical solutions can solve the problem in the prior art that it is rather inconvenient to adjust the web page color by adjusting the display color of the monitor.

Abstract: The present invention provides for compounds of formula (I) wherein A1, A2, A3, A4, X1, X2, Y1, L1, G1, Rx, and Ry have any of the values defined thereof in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).

Abstract: A method for manufacturing a bipolar transistor includes forming a first epitaxial layer on a semiconductor substrate, forming a second epitaxial layer on the first epitaxial layer, forming an oxide layer on the second epitaxial layer, etching the oxide layer to form an opening in which the second epitaxial layer is exposed, and forming a third epitaxial layer in the opening. The first and third epitaxial layers have a first-type conductivity, and the second epitaxial layer has a second-type conductivity.

Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.

Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti-apoptotic Bcl-2 protein.

Abstract: Exemplary embodiments are directed to devices and method for operating a charge pump. A method may include activating a first switch coupled between a capacitor and a ground voltage over a first period of a charging phase. The first period may coincide with a non-overlapping time between the charging phase and an output phase. The method may also include activating a second switch coupled between the capacitor and an input voltage over a second period of the charging phase, wherein the first period begins prior to the second period. Further, the method may include deactivating the second switch over a third period of the charging phase and deactivating the first switch over a fourth period of the charging phase, wherein the third period begins prior to the fourth period.

Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.

Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.

Abstract: The present invention provides new polyimide materials suitable for use in optically transparent fiber composites, ribbon composites, and optical communications applications. The polyimide compounds include monomeric repeat units comprising a fluorinated moiety and a fluorene cardo structure. The polyimides exhibit good optical transparency and have a low absolute thermo-optic coefficient (|dn/dT|).

Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.

Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti-apoptotic Bcl-2 protein.

Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti-apoptotic Bcl-2 protein.

Abstract: Compounds which inhibit the activity of anti-apoptotic Mcl-1 protein, compositions containing the compounds, and methods of treating diseases involving overexpressed or unregulated Mcl-1 protein are disclosed.

Abstract: The present invention relates to a valve assembly, the valve assembly comprising: a valve body having a first pressure chamber and a second pressure chamber, wherein the pressure of the first pressure chamber is lower than that of the second pressure chamber, and the pressure of the second pressure chamber is discharged to the first pressure chamber in response to the change of the pressure of the first pressure chamber; a blocking device arranged between the first pressure chamber and the second pressure chamber; and a valve stem arranged in the valve body with one end movably contacting the blocking device; and a diaphragm connected to the valve stem and adjacent to or arranged above the first pressure chamber; wherein when the pressure of the first pressure chamber is changed, the diaphragm forces the valve stem to move by sensing the pressure change of the first pressure chamber.