Abstract: Novel compounds, compositions, and methods of using and preparing the same, which may be useful for treating alpha-1 antitrypsin deficiency (AATD).

Abstract: The present invention relates to, inter alia, a novel crystalline free-plate habit or morphology, processes for preparing the crystalline free-plate habit, and uses of the crystalline free-plate habit of the L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid (Compound 1) in the treatment of S1P1 receptor-associated disorders, for example, diseases and disorders mediated by lymphocytes, transplant rejection, autoimmune diseases and disorders, inflammatory diseases and disorders (e.g., acute and chronic inflammatory conditions), cancer, and conditions characterized by an underlying defect in the vascular integrity or that are associated with angiogenesis such as may be pathologic (e.g., as may occur in inflammation, tumor development, and atherosclerosis).

Abstract: Techniques for performing an upgrade can include: defining integration points, each associated with a workflow processing point of an upgrade workflow of an upgrade infrastructure or framework; and performing processing by code of the upgrade infrastructure or framework that performs the upgrade workflow to upgrade a system, wherein the upgrade includes upgrading a first feature, facility or service of the system from a current version to a new version. The processing can include: dynamically determining, at runtime during execution of the upgrade workflow by the code of the upgrade infrastructure or framework, a set of code entities associated with a first of the integration points; executing code corresponding to workflow processing points, wherein a first of the workflow processing points is associated with the first integration point; and in response to said executing reaching the first workflow processing point, invoking each code entity of the set for upgrade processing.

Abstract: An analytics module included in a processing system receives performance feedback related to a broadcast media item. The performance feedback includes metadata associated with the feedback. Based on the metadata, the analytics module distinguishes between first performance feedback provided by automated programs and second performance feedback provided by valid users. The second performance feedback is transmitted to a media proposal server, but the first performance feedback is not. The media proposal server determines, based on the second performance feedback, that the broadcast media item is to be replaced by a replacement broadcast media item.

Abstract: The present invention relates to methods of processing lignocellulosic material to obtain hemicellulose sugars, cellulose sugars, lignin, cellulose and other high-value products. Also provided are hemicellulose sugars, cellulose sugars, lignin, cellulose, and other high-value products.

Abstract: A model display stand is an apparatus that is used to display model cars in a position simulating the act of burning rubber. The apparatus includes a base panel, a propping tab, a first smoke-cloud-shaped wall, a second smoke-cloud-shaped wall, a first smoke-trail-shaped protrusion, and a second smoke-trail-shaped protrusion. The base panel serves to support portions of a model car when the model car is mounted onto the apparatus. The propping tab serves to elevate portions of the model car to display the model car in a wheelie position. The first smoke-cloud-shaped wall and the second cloud-shaped wall surround the base panel and the model car mounted onto the base panel. Along with the first smoke-trail-shaped protrusion and the second smoke-trail-shaped protrusion, the first smoke-cloud-shaped wall and the second smoke-cloud-shaped wall also serve to simulate the act of burning rubber by the model car.

Abstract: An aircraft store ejector systems and subsystems thereof. Embodiments can include a two-reservoir re-pressurization system wherein a remote reservoir is used to maintain desired pressure in a local ejector reservoir. The system can include a release valve having a vent valve and valve piston. The release valve can control release of pressurized gas to a pitch control valve. The pitch control valve can be configured to distribute the pressurized gas between two or more ejector piston assemblies. One or more of the ejector piston assemblies can include multiple concentric piston stages and piston chambers, the piston chambers configured to contain a volume of gas. The ejector piston assemblies can be configured to compress the volume of gas within the piston chambers as the piston stages are extended out from the aircraft. Such compression can provide a return force to the piston stages.

Abstract: Operations and Maintenance Design drawing maintenance, As-Built drawing conformance, and Record drawing conformance processes for protecting the integrity of dynamically modified files for Brownfield Assets through all phases of a drawing's lifecycle.

Abstract: A comprehensive addiction treatment method with a medication delivery system of subcutaneous implant of micro-pellets in patients, which may include a method of identification at an advanced video communication system through facial recognition, voice recognition and/or a recognition of an RFID microchip implanted in a patient. The identification will be transmitted over the Internet to a database at a secure server to initiate a computer program to stream video content, computer generated communication and/or a live video to be transmitted to an audio-visual system that may be capable of displaying a life-size video image of a live caregiver or a computer generated avatar of a caregiver within a three dimensional setting for real time two-way communication with apparent eye contact.

Abstract: An aircraft store ejector systems and subsystems thereof. Embodiments can include a two-reservoir re-pressurization system wherein a remote reservoir is used to maintain desired pressure in a local ejector reservoir. The system can include a release valve having a vent valve and valve piston. The release valve can control release of pressurized gas to a pitch control valve. The pitch control valve can be configured to distribute the pressurized gas between two or more ejector piston assemblies. One or more of the ejector piston assemblies can include multiple concentric piston stages and piston chambers, the piston chambers configured to contain a volume of gas. The ejector piston assemblies can be configured to compress the volume of gas within the piston chambers as the piston stages are extended out from the aircraft. Such compression can provide a return force to the piston stages.

Abstract: Techniques for performing an upgrade can include: defining integration points, each associated with a workflow processing point of an upgrade workflow; associating code entities with the integration points; and performing processing that performs the upgrade workflow to upgrade a system, wherein the upgrade includes upgrading a first feature, facility or service of the system from a current version to a new version, wherein the processing further includes: executing code corresponding to workflow processing points of the upgrade workflow, wherein a first workflow processing point of the upgrade workflow is associated with a first of the integration points; and in response to said executing reaching the first workflow processing point corresponding to the first integration point, invoking a first code entity associated with the first integration point, wherein said first code entity performs customized processing in connection with upgrading the first feature, facility or service in the system.

Abstract: Operations and Maintenance Design drawing maintenance, As-Built drawing conformance, and Record drawing conformance processes for protecting the integrity of dynamically modified files through all phases of a drawing's lifecycle.

Abstract: A universal model display stand is an apparatus that is used to display model cars in a position simulating the act of burning rubber. The apparatus includes a base panel, a propping tab, a first smoke-cloud-shaped wall, a second smoke-cloud-shaped wall, a first smoke-trail-shaped protrusion, and a second smoke-trail-shaped protrusion. The base panel serves to support portions of a model car when the model car is mounted onto the apparatus. The propping tab serves to elevate portions of the model car to display the model car in a wheelie position. The first smoke-cloud-shaped wall and the second cloud-shaped wall surround the base panel and the model car mounted onto the base panel. Along with the first smoke-trail-shaped protrusion and the second smoke-trail-shaped protrusion, the first smoke-cloud-shaped wall and the second smoke-cloud-shaped wall also serve to simulate the act of burning rubber by the model car.

Abstract: According to various embodiments, a cable and termination system includes a cable, a liquidtight conduit at least partially surrounding the cable, and a termination. The cable includes a cable core comprising three insulated phase conductors, three ground conductors, and filler interspersed within the cable core to force the ground connectors into symmetrical, geometric location with a corresponding phase conductor and a second phase conductor, and a cable wrap applied over the cable core. The termination includes a first connector, a second, reverse-threaded connector including an exterior metal body and a male metal body coupled with a collet sleeve. Various embodiments of the first connector are also described.

Abstract: According to various embodiments, a cable and termination system includes a cable, a liquidtight conduit at least partially surrounding the cable, and a termination. The cable includes a cable core comprising three insulated phase conductors, three ground conductors, and filler interspersed within the cable core to force the ground connectors into symmetrical, geometric location with a corresponding phase conductor and a second phase conductor, and a cable wrap applied over the cable core. The termination includes a first connector, a second, reverse-threaded connector including an exterior metal body and a male metal body coupled with a collet sleeve. Various embodiments of the first connector are also described.

Abstract: Techniques for performing an upgrade can include: defining integration points each associated with a workflow processing point included in an upgrade workflow; receiving command lists each include commands of an integration point; associating each command of a command list with a code entity; performing processing that performs an upgrade workflow to upgrade a system, wherein the processing includes: executing code corresponding to the upgrade workflow, wherein a workflow processing point of the workflow is associated with a first integration point; and in response to said executing reaching the workflow processing point corresponding to the first integration point, performing second processing including: executing commands of a command list associated with the first integration point; and for each command executed, invoking a corresponding code entity that performs customized processing in connection with upgrading a first feature, facility or service in the system.

Abstract: Techniques for performing an upgrade can include: defining integration points, each associated with a workflow processing point of an upgrade workflow; associating code entities with the integration points; and performing processing that performs the upgrade workflow to upgrade a system, wherein the upgrade includes upgrading a first feature, facility or service of the system from a current version to a new version, wherein the processing further includes: executing code corresponding to workflow processing points of the upgrade workflow, wherein a first workflow processing point of the upgrade workflow is associated with a first of the integration points; and in response to said executing reaching the first workflow processing point corresponding to the first integration point, invoking a first code entity associated with the first integration point, wherein said first code entity performs customized processing in connection with upgrading the first feature, facility or service in the system.

Abstract: An aircraft store ejector systems and subsystems thereof. Embodiments can include a two-reservoir re-pressurization system wherein a remote reservoir is used to maintain desired pressure in a local ejector reservoir. The system can include a release valve having a vent valve and valve piston. The release valve can control release of pressurized gas to a pitch control valve. The pitch control valve can be configured to distribute the pressurized gas between two or more ejector piston assemblies. One or more of the ejector piston assemblies can include multiple concentric piston stages and piston chambers, the piston chambers configured to contain a volume of gas. The ejector piston assemblies can be configured to compress the volume of gas within the piston chambers as the piston stages are extended out from the aircraft. Such compression can provide a return force to the piston stages.

Abstract: An aircraft store ejector systems and subsystems thereof. Embodiments can include a two-reservoir re-pressurization system wherein a remote reservoir is used to maintain desired pressure in a local ejector reservoir. The system can include a release valve having a vent valve and valve piston. The release valve can control release of pressurized gas to a pitch control valve. The pitch control valve can be configured to distribute the pressurized gas between two or more ejector piston assemblies. One or more of the ejector piston assemblies can include multiple concentric piston stages and piston chambers, the piston chambers configured to contain a volume of gas. The ejector piston assemblies can be configured to compress the volume of gas within the piston chambers as the piston stages are extended out from the aircraft. Such compression can provide a return force to the piston stages.

Abstract: A portable outdoor game that may include a ramp, a target, and one or more projectiles. The ramp may include an elongated runner and an elevation structure. The elevation structure may be positioned at one end of the runner and lift that end of the runner from a playing surface, creating an angled incline in the runner relative to the playing surface. Projectiles may roll or slide across the runner in the direction of the elevation structure. The projectiles may become airborne after traveling over the elevation structure and land within or near the target.