Abstract: Apparatus and methods for high performance liquid chromatography. The apparatus includes a preparation loop comprising two linear stepping pumps, a sample loop comprising a sample injector, a chromatography column, and a detector device. The detector device can include a flash lamp, a flow cell, and a light sensor comprising an entrance slit, a grating; and a charge-coupled device array.

Abstract: Disclosed herein is a device for characterizing a biological sample or an airborne sample. According to embodiments of the present disclosure, the device comprises an electrospray source, a mass analyzer, a charge detector, and optionally, an ion guide. The present device is useful in analyzing the particle population in the biological or airborne sample based on the mass to charge (m/z) ratio and the charge (z) of each particle. Also disclosed herein are the methods of making a diagnosis of cancer by use of the present device, and methods of determining the mass distribution of particles in an airborne sample.

Abstract: A mattress for patient care. The mattress includes a number of compressible cells and a number of sensors corresponding to the number of compressible cells. Each compressible cell is configured to contact, when inflated, a user in a contact area of a plurality of contact areas of the user. Each sensor is configured to generate a number of measurements, wherein each measurement relates to the contact area of a corresponding compressible cell. Each sensor is further configured to send the number of measurements to a pressure control device.

Abstract: Disclosed herein is a device for characterizing a biological sample or an airborne sample. According to embodiments of the present disclosure, the device comprises an electrospray source, a mass analyzer, a charge detector, and optionally, an ion guide. The present device is useful in analyzing the particle population in the biological or airborne sample based on the mass to charge (m/z) ratio and the charge (z) of each particle. Also disclosed herein are the methods of making a diagnosis of cancer by use of the present device, and methods of determining the mass distribution of particles in an airborne sample.

Abstract: An adjustable container carrying strap structure includes a strip-shaped carrying strap and a container sleeving assembly. The strip-shaped carrying strap includes a first end, a second end, and a carrying strap body. The container sleeving assembly includes two sleeve ropes and an adjusting element, where each sleeve rope includes a first rope end, a second rope end, and a rope body, the first rope end of each sleeve rope is connected to the first end, the second rope end of each sleeve rope is connected to the second end, and the adjusting element is assembled on the two rope bodies of the two sleeve ropes, so that the adjusting element, the two rope bodies, and the first end of the strip-shaped carrying strap encircle a container sleeving hole. The adjusting element can slide relatively along the two rope bodies so as to adjust the size of the container sleeving hole.

Abstract: An adjustable container carrying strap structure includes a strip-shaped carrying strap and a container sleeving assembly. The strip-shaped carrying strap includes a first end, a second end, and a carrying strap body. The container sleeving assembly includes two sleeve ropes and an adjusting element, where each sleeve rope includes a first rope end, a second rope end, and a rope body, the first rope end of each sleeve rope is connected to the first end, the second rope end of each sleeve rope is connected to the second end, and the adjusting element is assembled on the two rope bodies of the two sleeve ropes, so that the adjusting element, the two rope bodies, and the first end of the strip-shaped carrying strap encircle a container sleeving hole. The adjusting element can slide relatively along the two rope bodies so as to adjust the size of the container sleeving hole.

Abstract: The invention provides a method of treating or reducing the severity of thyroid-associated ophthalmopathy (TAO), also known as thyroid eye disease (TED) or Graves' ophthalmopathy or orbitopathy (GO), or a symptom or aspect thereof, in subjects that have undergone prior treatment for TAO, TED, or GO, and either did not respond to said prior treatment or relapsed after said prior treatment. The invention also provides antibodies, or antigen binding fragments thereof, and pharmaceutical compositions useful in the disclosed methods.

Abstract: Apparatus and methods for high performance liquid chromatography. The apparatus includes a preparation loop comprising two linear stepping pumps, a sample loop comprising a sample injector, a chromatography column, and a detector device. The detector device can include a flash lamp, a flow cell, and a light sensor comprising an entrance slit, a grating; and a charge-coupled device array.

Abstract: Disclosed herein are anti-RGMa antibodies and methods of using these antibodies to treat multiple sclerosis, including relapsing forms of multiple sclerosis such as relapsing-remitting multiple sclerosis or relapsing-secondary progressive multiple sclerosis.

Abstract: A mattress for patient care. The mattress includes a number of compressible cells and a number of sensors corresponding to the number of compressible cells. Each compressible cell is configured to contact, when inflated, a user in a contact area of a plurality of contact areas of the user. Each sensor is configured to generate a number of measurements, wherein each measurement relates to the contact area of a corresponding compressible cell. Each sensor is further configured to send the number of measurements to a pressure control device.

Abstract: Apparatus and methods for high performance liquid chromatography. The apparatus includes a preparation loop comprising two linear stepping pumps, a sample loop comprising a sample injector, a chromatography column, and a detector device. The detector device can include a flash lamp, a flow cell, and a light sensor comprising an entrance slit, a grating; and a charge-coupled device array.

Abstract: A retractable safety syringe includes a retractable needle hub holding a needle and having a first guiding means; and a hollow barrel having a second guiding means set correspondingly to the first guiding means; and a collapsible plunger comprising of a first plunger element having a protrusion releasably coupled with a second plunger element having a longitudinal slot with a pinched zone to curb the movement of said protrusion; and a spring disposed between the needle hub and hollow barrel and acts between the needle hub and the hollow barrel. The uncoupling of the collapsible plunger triggers the retraction mechanism to enable the needle hub to retract into the barrel by the decompression force of a spring. The reliability of retraction is further improved by a longitudinal slot and a protrusion to facilitate the retreating of the collapsible plunger in an orderly way.

Abstract: A stability analyzing apparatus is in cooperation with a DC power system having a bus terminal connected to at least a load, and comprises a perturbation signal generating module, a signal processing module and a determining module. The perturbation signal generating module generates a perturbation signal injected into the bus terminal to obtain a transfer function of the bus terminal impedance. The signal processing module is electrically connected to the perturbation signal generating module and calculates the slope of the transfer function of the bus terminal impedance to obtain a transfer function of the bus terminal impedance slope. The determining module is electrically connected to the signal processing module and determines the stability tendency of the DC power system according to the transfer function of the bus terminal impedance slope. A stability analyzing method is also disclosed.

Abstract: Disclosed herein are anti-RGMa antibodies and methods of using these antibodies to treat multiple sclerosis, including relapsing forms of multiple sclerosis such as relapsing-remitting multiple sclerosis or relapsing-secondary progressive multiple sclerosis.

Abstract: The present disclosure provides methods of utilizing Syk inhibiting compounds in the treatment for graft versus host disease (GVHD) in a human, including acute graft versus host disease (aGVHD) and chronic graft versus host disease (cGVHD), including the use of compounds selected from the group consisting of the formulas below:

Abstract: Apparatus and methods for creating a pulsed ion beam. The pulsed ion beam can be used for performing mass spectrometry. A pulsed solenoid valve can provide a pulsed ion beam from an electrospray in a pre-vacuum chamber. The pulsed ion beam can enter a high vacuum region and a mass analyzer for mass spectrometry.

Abstract: Apparatus and methods for automatic amino acid sequencing of a glycopeptide by mass spectrometry. The glycopeptide is fragmented by higher energy collision dissociation fragmentation, and sequentially fragmented by collision induced dissociation fragmentation. The glycopeptide Y1 ion is isolated, and the mass spectra of fragmented glycopeptide Y1 ions provide mass spectral peaks corresponding to the amino acid sequence of the glycopeptide.

Abstract: An AC/DC conversion circuit of a power conversion apparatus receives an AC signal and has a switching element. A voltage sensing circuit generates a voltage reference signal according to an AC voltage signal. A harmonic generation circuit generates a harmonic injection signal according to the voltage reference signal. A subtraction circuit of a maximum power tracking circuit outputs a first DC signal and a second DC signal according to the voltage reference signal. An arithmetic circuit outputs a reference signal. A current sensing circuit outputs a feedforward signal according to one phase of an AC current signal. A current control circuit outputs an error signal according to the reference signal and the feedforward signal. A pulse width modulation circuit outputs a control signal to control the switching element according to the error signal and the harmonic injection signal, so that an aerogenerator operates at the maximum power approximation line.

Abstract: Methods and apparatuses for portable mass spectrometry are disclosed. The apparatuses comprise at least one source of ionized analyte, at least one frequency scanning subsystem, at least one detector, and optionally at least one vacuum pump, and are portable. In some embodiments, the apparatuses comprise multiple sources of ionized analyte and/or are configured to obtain mass spectra of a large analyte, such as analyte with an m/z ratio of at least 105, or analyte with a molecular weight of at least 105 Da, as well as mass spectra of small molecule analyte. In some embodiments, the methods comprise obtaining mass spectra with a portable apparatus described above.

Abstract: Apparatus and methods for automatic amino acid sequencing of a glycopeptide by mass spectrometry. The glycopeptide is fragmented by higher energy collision dissociation fragmentation, and sequentially fragmented by collision induced dissociation fragmentation. The glycopeptide Y1 ion is isolated, and the mass spectra of fragmented glycopeptide Y1 ions provide mass spectral peaks corresponding to the amino acid sequence of the glycopeptide.